10 enrolling by invitation. 10 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Enrolling by invitation 10 |
| Phase 2 | 5 | Enrolling by invitation 5 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy Test of Curcuminoid Standardized Turmeric Capsules to Improving Inflammatory Biomarkers in Osteoarthritis Genu Curcuminoid Standardized Turmeric Capsules, Placebo - Osteoarthritis | Phase 2 / Phase 3 | Enrolling by invitation | Gadjah Mada University | 72 | 2025-06-01 | 2025-09-19 |
| The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin An aqueous solution containing CBD and CBN, The aqueous solution of placebo - Myalgia, Muscle Pain | Phase 2 / Phase 3 | Enrolling by invitation | Wroclaw Medical University | 42 | 2025-04-01 | 2026-03-06 |
| RCT to Test Regional Anesthesia Effect on Decreased Opiate Use Bupivacaine, Saline (NaCl 0,9 %) (placebo) - Postoperative Pain | Phase 3 | Enrolling by invitation | United States Naval Medical Center, Portsmouth | 50 | 2024-12-01 | 2025-10-09 |
| Personalized Evaluation of Susptected Myocardial Ischemia Clinical Likelihood (CL) Model-Based Diagnostic Strategy, Standard of care treatment - Chronic Coronary Syndrome, Angina Pectoris | Phase 3 | Enrolling by invitation | Gødstrup Hospital | 2000 | 2024-11-20 | 2025-12-19 |
| Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm Endothelin Receptor Antagonist, Placebo control - Coronary Spasm | Phase 2 / Phase 3 | Enrolling by invitation | Radboud University Medical Center | 100 | 2024-11-11 | 2024-11-18 |
| Extended Oral Tranexamic Acid After Total Knee Arthroplasty Tranexamic acid, Placebo - Osteo Arthritis Knee, Pain, Postoperative | Phase 3 | Enrolling by invitation | Campbell Clinic | 120 | 2024-09-17 | 2026-08-13 |
| NSAIDS Following Elective Lumbar Spine Fusion Ketorolac, Naproxen, Standard Postoperative Pain Management - NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion | Phase 3 | Enrolling by invitation | Rothman Institute Orthopaedics | 428 | 2024-07-08 | 2026-08-04 |
| Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion Exparel, Bupivacain - Back Pain, Surgery-Complications | Phase 2 / Phase 3 | Enrolling by invitation | Foundation for Orthopaedic Research and Education | 76 | 2024-04-30 | 2026-09-09 |
| Efficacy of Liposomal Bupivacaine Post Septorhinoplasty Liposomal Bupivacaine, 0.25% bupivacaine with 1:200,000 epinephrine, Placebo - Saline solution - Rhinoplasty, Pain Management | Phase 3 | Enrolling by invitation | Jessyka Lighthall | 72 | 2024-02-05 | 2026-04-03 |
| Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride - Pain, Postoperative, Opioid Use | Phase 2 / Phase 3 | Enrolling by invitation | Rutgers, The State University of New Jersey | 150 | 2024-01-11 | 2026-02-17 |
Pain, Postoperative (5) · Angina Pectoris (2) · Agnosia (1) · Angina Pectoris, Variant (1) · Arteriosclerosis (1) · Back Pain (1) · Coronary Artery Disease (1) · Facial Pain (1) · Headache (1) · Heart Diseases (1) · Myalgia (1) · Myocardial Ischemia (1) · Osteoarthritis (1) · Tension-Type Headache (1)
Neurologic Manifestations (10) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (10) · Pathologic Processes (5) · Postoperative Complications (5) · Cardiovascular Diseases (3) · Chest Pain (2) · Heart Diseases (2) · Musculoskeletal Diseases (2) · Nervous System Diseases (2) · Vascular Diseases (2) · Angina, Unstable (1) · Arterial Occlusive Diseases (1) · Arthritis (1)
Bupivacaine (4) · Bosentan (1) · Cannabinol (1) · Endothelin Receptor Antagonists (1) · Epinephrine (1) · Ketorolac (1) · Naproxen (1) · Sodium Chloride (1) · Tranexamic Acid (1) · microcrystalline cellulose (1)
Campbell Clinic (1) · Foundation for Orthopaedic Research and Education (1) · Gadjah Mada University (1) · Gødstrup Hospital (1) · Jessyka Lighthall (1) · Radboud University Medical Center (1) · Rothman Institute Orthopaedics (1) · Rutgers, The State University of New Jersey (1) · United States Naval Medical Center, Portsmouth (1) · Wroclaw Medical University (1)
United States (6) · Denmark (1) · Indonesia (1) · Netherlands (1) · Poland (1)
Christopher Holland, MD, MS (1) · Jessyka Lighthall, MD (1) · John Small, MD (1) · Leonard Y Lee, MD (1) · Peter Damman, MD, PhD (1) · Tokunbo I Ayeni, MD (1)