10 completed, 10 unknown, 7 recruiting, 2 active not recruiting. 10 Not applicable, 8 Phase 4, 4 Phase 2, 4 Phase 3.
Follow Angina Pectoris, Variant: new trials by email Literature Review of Angina Pectoris, Variant trials Research Report on Angina Pectoris, Variant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Invasive Evaluation and Phenotype-Guided Treatment of ANOCA in Women Invasive Coronary Functional and Morphological Assessment, Pharmacological treatment will be individualized according to the invasive coronary phenotype identified. Treatment may include antianginal therapy, vasodilator therapy, endothelial function-targeted - ANOCA - Angina With Non-obstructive Coronary Arteries, Coronary Microvascular Dysfunction (CMD) | Not applicable | Not yet recruiting | Hospital de Clínicas Dr. Manuel Quintela | 50 | 2026-05-15 | 2026-05-18 |
| The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina Pectoris Vericiguat - Vasospastic Angina | Phase 2 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 57 | 2025-02-10 | 2026-07-29 |
| Cardioneuroablation for Variant Angina cardioneuroablation - Variant Angina | Not applicable | Active not recruiting | Zhibing Lu | 16 | 2025-02-07 | 2025-11-25 |
| POLish Registry of CArdioneuroablation and CArdioneuromodulation cardioneuroablation, SN sparing hybrid ablation, Cardiac sympathetic denervation - Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS | Recruiting | SABAMED Medical Center Ltd. | 1000 | 2024-11-21 | 2025-09-29 | |
| Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm Endothelin Receptor Antagonist, Placebo control - Coronary Spasm | Phase 2 / Phase 3 | Enrolling by invitation | Radboud University Medical Center | 100 | 2024-11-11 | 2024-11-18 |
| Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries Amlodipine, Nebivolol, Placebo - Angina Pectoris, Microvascular Angina | Phase 2 / Phase 3 | Recruiting | Stanford University | 150 | 2024-10-10 | 2024-11-27 |
| Transcutaneous Electrical Nerve Stimulation in Patients With Angina and Non-Obstructive Coronary Arteries Transcutaneous Electrical Nerve Stimulation - Microvascular Angina, Vasospastic Angina | Not applicable | Unknown | Catharina Ziekenhuis Eindhoven | 20 | 2024-03-13 | 2024-05-06 |
| Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic ANOCA, ANOCA - Angina With Non-obstructive Coronary Arteries | Recruiting | University Hospital, Motol | 1000 | 2023-04-20 | 2025-08-05 | |
| ReACHallenge Trial: Acetylcholine Rechallenge After Pretreatment With Vasoactive Drugs Acetylcholine rechallenge - Angina Pectoris, Variant, Angina Pectoris; Spasm-Induced | Not applicable | Unknown | University Hospital, Antwerp | 30 | 2023-01-09 | 2023-01-19 |
| Assessing the Effect of the 'Wavy' Application, on Stress and Burden of Disease in Women With INOCA Wavy stress application - Stress, Ischemia | Not applicable | Completed | Radboud University Medical Center | 117 | 2022-08-01 | 2024-01-19 |
| Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease Bisoprolol, Diltiazem, Placebo - Coronary Microvascular Dysfunction, Microvascular Angina | Phase 4 | Unknown | Charite University, Berlin, Germany | 132 | 2022-03-04 | 2022-03-24 |
| Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial). Coronary angiography, OCT imaging, Percutaneous coronary intervention (PCI): - Myocardial Infarction With Non-Obstructive Coronary Arteries | Phase 4 | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 120 | 2021-07-01 | 2024-07-26 |
| iCorMicA - Stratified Medicine in Angina Disclosure of IDP results, IDP performed but results not disclosed - Microvascular Angina, Angina, Stable | Not applicable | Recruiting | NHS Greater Glasgow and Clyde | 1500 | 2020-12-30 | 2026-04-09 |
| Coronary Microcirculatory Disease and Inflammation in Patients With Chronic Coronary Syndrome and no Significant Coronary Artery Stenosis Comprehensive functional diagnostics of coronary circulation - Coronary Artery Disease, Ischemia and No Obstructive Coronary Arteries | Unknown | Bartlomiej Guzik | 160 | 2020-07-24 | 2022-04-06 | |
| Immunomodulatory Therapy & VSA glucocorticosteroids and/or intravenous immunoglobulin - Vasospastic Angina | Completed | Dao Wen Wang | 71 | 2018-10-01 | 2024-11-20 | |
| Myocardial Ischemia Without Obstructive Coronary Stenoses Invasive coronary endothelium-dependent and non-endothelium-dependent physiological assessment - Myocardial Ischemia, Non-Obstructive Coronary Atherosclerosis | Recruiting | Hospital San Carlos, Madrid | 600 | 2017-11-08 | 2021-04-26 | |
| Coronary Microvascular Function and CT Coronary Angiography (CorCTCA) Stratified medicine involving a diagnostic intervention - Angina, Stable, Angina Pectoris, Variant | Not applicable | Active not recruiting | NHS National Waiting Times Centre Board | 250 | 2017-08-31 | 2024-10-29 |
| Statin Therapy In Patients With Vasospastic Angina Atorvastatin, Placebo - Angina Pectoris, Variant, Statins, HMG-CoA | Phase 4 | Withdrawn | Seung-Jung Park | 2017-07-01 | 2017-06-15 | |
| BVS Implantation in Patients With Variant Angina and MODerate Coronary Artery Disease BVS+OMT - Angina Pectoris, Variant | Phase 4 | Withdrawn | Seung-Jung Park | 2017-04-19 | 2024-01-02 | |
| Time Gain in the Diagnosis Myocardial Infarction by Troponin Point of Care Testing in the Emergency Room Laboratory based troponin test, Point of care based troponin test 1, Point of care based troponin test 2 - Non STEMI, Angina Pectoris | Completed | Ziekenhuis Oost-Limburg | 66 | 2017-02-01 | 2021-04-21 |
Showing 20 of 34. Sign in to see all of them.
Microvascular Angina (10) · Angina Pectoris (6) · Angina, Stable (6) · Coronary Artery Disease (4) · Ischemia (3) · Myocardial Ischemia (3) · Angina, Unstable (2) · Coronary Vasospasm (2) · Hypertension (2) · MINOCA (2) · Non-ST Elevated Myocardial Infarction (2) · Autonomic Nervous System Diseases (1) · Death, Sudden, Cardiac (1) · Hypotension, Orthostatic (1)
Cardiovascular Diseases (34) · Chest Pain (34) · Heart Diseases (34) · Neurologic Manifestations (34) · Pain (34) · Pathological Conditions, Signs and Symptoms (34) · Signs and Symptoms (34) · Vascular Diseases (34) · Angina, Unstable (32) · Myocardial Ischemia (31) · Angina Pectoris (28) · Pathologic Processes (8) · Coronary Disease (5) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4)
Amlodipine (4) · Atorvastatin (4) · Adrenergic beta-Antagonists (2) · Cilostazol (2) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (2) · Percutaneous Coronary Intervention (2) · Anticoagulants (1) · Ascorbic Acid (1) · Bisoprolol (1) · Bosentan (1) · Calcium Channel Blockers (1) · Defibrillators, Implantable (1) · Diltiazem (1) · Endothelin Receptor Antagonists (1) · Nebivolol (1)
Korea Otsuka Pharmaceutical Co., Ltd. (3) · Radboud University Medical Center (2) · Roxane Laboratories (2) · Samsung Medical Center (2) · Seung-Jung Park (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Bartlomiej Guzik (1) · Catharina Ziekenhuis Eindhoven (1) · Charite University, Berlin, Germany (1) · Dao Wen Wang (1) · Dong-A University (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hospital San Carlos, Madrid (1) · Hospital de Clínicas Dr. Manuel Quintela (1) · Kee-joon Choi (1)
South Korea (11) · Netherlands (5) · United States (4) · China (3) · Poland (3) · Belgium (2) · Switzerland (2) · United Kingdom (2) · Czechia (1) · Germany (1) · Ireland (1) · Italy (1) · Spain (1) · Uruguay (1)
Colin Berry, MBChB, PhD (1) · Hernan Mejia-Renteria, MD, PhD (1) · Hyo-Soo Kim, Kim (1) · Hyun-chul Gwon, MD,PhD (1) · Jacek Legutko, MD, PhD, Professor (1) · Javier Escaned, MD, PhD (1) · Jennifer Tremmel, MD (1) · June Hong Kim, MD (1) · Junghong Kim, MD (1) · Katriona Brooksbank, PhD (1) · Marta Kornaszewska, MD (1) · Moo Hyun Kim, M.D. (1) · Nicola Cosentino, MD (1)
PMID 16357399, PMID 19716193, PMID 22236508, PMID 22247633, PMID 23453453, PMID 24934484, PMID 25273915, PMID 27414736, PMID 35734824, PMID 36534493, PMID 36807273, PMID 37795617, PMID 39297854, PMID 39508144, PMID 39691038, PMID 40274007, PMID 40308206, PMID 41826400, PMID 42034271, PMID 42409349, PMID 42517514, PMID 42670734