66 completed, 26 unknown, 13 recruiting, 10 not yet recruiting. 80 Not applicable, 11 Phase 3, 7 Phase 2, 4 Phase 4, 1 Phase 1.
Follow Tension-Type Headache: new trials by email Literature Review of Tension-Type Headache trials Research Report on Tension-Type Headache
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevalence of Primary Headache in Multiple Sclerosis Patients Multiple Sclerosis, Primary Headache Disorders | Not yet recruiting | Assiut University | 100 | 2026-10-01 | 2026-09-17 | |
| Influence of Osteopathic Intervention on Cervical Muscles in Tension Headaches in Women Placebo Technique, Stretching technique, Inhibition of the suboccipital - Tension Headaches | Not applicable | Not yet recruiting | Escola Superior de Tecnologia da Saúde do Porto | 43 | 2026-09-01 | 2026-06-25 |
| Tension-type Headache and Its Association Tension-Type Headache, Sleep Disturbance | Not yet recruiting | Assiut University | 199 | 2026-08-10 | 2026-08-24 | |
| Fire Needling Plus Filiform Needling for Chronic Migraine With Comorbid Tension-Type Headache filiform needling, fire needling combined with filiform needling - Chronic Migraine, Tension-type Headache | Not applicable | Not yet recruiting | Beijing Hospital of Traditional Chinese Medicine | 88 | 2026-08-01 | 2026-06-08 |
| Efficacy of a Multimodal Physiotherapy Program and Mobile-App Guided Meditation in Adults With Frequent or Chronic Tension-Type Headache Multimodal Physiotherapy for Tension-Type Headache, Guided Meditation Using Insight Timer App - Tension-Type Headache, Chronic Tension-type Headache | Not applicable | Not yet recruiting | Universidad de Granada | 78 | 2026-07-01 | 2026-05-11 |
| Temple Massager System Study in Women Ages 35-65 Temple Massager System - Tension Headaches, Stress | Completed | Meisch Temple Massager, Inc. | 68 | 2026-06-10 | 2026-09-23 | |
| High- vs Standard-Dose Intravenous Magnesium for Acute Headache Magnesium Sulfate 2 grams, Magnesium Sulfate 4 G, Paracetamol 1 g - Acute Headache, Migraine | Not applicable | Recruiting | University of Monastir | 300 | 2026-06-01 | 2026-08-21 |
| Pericranial and General Sensitivity in Patients With Primary Headache Pericranial Tenderness Assessment, Pressure Pain Threshold Assessment, Temporomandibular Disorder Assessment - Primary Headache Disorders, Tension Headache | Enrolling by invitation | Universitat Internacional de Catalunya | 120 | 2026-03-31 | 2026-04-07 | |
| Effect of Laser Acupuncture on Tension Headache in Post-Pubertal Females Low energy laser acupuncture, Myofascial release technique - Tension Headache | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-02-20 | 2026-02-18 |
| Treatment of Tension-type Headache by Zhixuan Analgesic Tablets Zhixuan Analgesic Tablet, Placebo - Frequent Episodic Tension-Type Headache | Phase 4 | Recruiting | Tongji Hospital | 212 | 2026-01-01 | 2026-10-14 |
| Desvenlafaxine for Preventive Treatment of Frequent Episodic Tension-type Headache Desvenlafaxine, Placebo - Tension Type Headache | Not applicable | Active not recruiting | Tongji Hospital | 432 | 2025-12-01 | 2026-01-22 |
| BioTenCer: Biofeedback as Preventive Treatment in Tension Type Headache Cerebri-TTH biofeedback, headache diary - Tension Type Headache | Not applicable | Recruiting | Helse Nord-Trøndelag HF | 300 | 2025-10-17 | 2026-07-21 |
| Effect of Manuel Therapy on Tension Type Headache in Menopausal and Premenopasual Women Manuel Therapy - Tension Type Headache | Not applicable | Recruiting | Necmettin Erbakan University | 50 | 2025-10-01 | 2026-05-20 |
| Turkish Version of the Headache Screening Questionnaire Headache Screening Questionare - Migraine, Tension Type Headache | Not yet recruiting | Başakşehir Çam & Sakura City Hospital | 200 | 2025-07-15 | 2025-07-15 | |
| 0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment 0.5% Bupivacaine HCl, standard IV treatment for headache - Headache, Migraine | Phase 3 | Not yet recruiting | HCA Florida North Florida Hospital | 100 | 2025-05-01 | 2025-04-24 |
| The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin An aqueous solution containing CBD and CBN, The aqueous solution of placebo - Myalgia, Muscle Pain | Phase 2 / Phase 3 | Enrolling by invitation | Wroclaw Medical University | 42 | 2025-04-01 | 2026-03-06 |
| Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin Blood CB1, CB2, TRPV-1 concentration measurement - Myalgia, Muscle Pain | Enrolling by invitation | Wroclaw Medical University | 102 | 2025-04-01 | 2026-03-06 | |
| Muscle Function and Tenderness Differences in Headache Patients Muscle function - Migraine, Tension Headache | Enrolling by invitation | Danish Headache Center | 90 | 2025-02-28 | 2025-03-10 | |
| to Stuidy the Effect of Cognitive Behavior Threapy CBT on Problematic Smartphone Use Patients With Tension Type Headache cognitive behavioral therapy, sub-occipital inhibitory pressure, deep friction massage - Tension Type Headache, Smartphone Addiction | Not applicable | Completed | Hatem Mostafa | 64 | 2025-01-29 | 2026-09-16 |
| Forward Head Posture Differences in Tension Headaches forward head posture , resting scapular alignment and dynamic scapular kinematics - Tension-Type Headache | Active not recruiting | Cairo University | 50 | 2025-01-16 | 2026-07-24 |
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Migraine Disorders (44) · Headache (27) · Headache Disorders (11) · Cluster Headache (8) · Headache Disorders, Primary (8) · Fibromyalgia (6) · Neck Pain (6) · Chronic Pain (5) · Pain (5) · Post-Traumatic Headache (5) · Depression (4) · Facial Pain (4) · Headache Disorders, Secondary (4) · Motor Activity (4)
Brain Diseases (131) · Central Nervous System Diseases (131) · Nervous System Diseases (131) · Headache Disorders, Primary (123) · Headache Disorders (120) · Pathological Conditions, Signs and Symptoms (49) · Neurologic Manifestations (48) · Signs and Symptoms (48) · Pain (40) · Muscular Diseases (12) · Musculoskeletal Diseases (12) · Behavior (10) · Neuromuscular Diseases (9) · Pathologic Processes (9) · Trigeminal Autonomic Cephalalgias (8)
Musculoskeletal Manipulations (7) · Dry Needling (6) · Exercise (5) · Massage (3) · Myofascial Release Therapy (3) · Combined Modality Therapy (2) · Control Groups (2) · Electroacupuncture (2) · Exercise Therapy (2) · High-Energy Shock Waves (2) · Longitudinal Studies (2) · Manipulation, Spinal (2) · Metoclopramide (2) · Resistance Training (2) · Yoga (2)
Danish Headache Center (8) · University of Valencia (6) · Cairo University (5) · Ankara City Hospital Bilkent (2) · Assiut University (2) · Duke University (2) · Escola Superior de Tecnologia da Saúde do Porto (2) · Gazi University (2) · GlaxoSmithKline (2) · Helse Nord-Trøndelag HF (2) · Montefiore Medical Center (2) · National and Kapodistrian University of Athens (2) · Riphah International University (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Tongji Hospital (2)
United States (20) · Turkey (Türkiye) (18) · Spain (13) · Denmark (9) · China (7) · Egypt (7) · Belgium (5) · Pakistan (5) · Canada (4) · Norway (3) · United Kingdom (3) · Brazil (2) · Germany (2) · Greece (2) · Italy (2)
Albert Moraska, PhD (2) · Kaiming Liu, Doctor (2) · Alessandro Ugolini, DDS (1) · Andrea Nackley, PhD (1) · Anuj Bhatia, MD FRCPC (1) · Barbara Cagnie, Prof. Dr. (1) · Benjamin W. Friedman, MD,MS (1)
PMID 12841373, PMID 16052775, PMID 16183246, PMID 16553016, PMID 17165292, PMID 17323720, PMID 17475943, PMID 17602994, PMID 18187725, PMID 18331805, PMID 19272275, PMID 19548407, PMID 19775434, PMID 20194385, PMID 20647241, PMID 20961685, PMID 21837291, PMID 22253751, PMID 22364327, PMID 22467991, PMID 22480810, PMID 23115152, PMID 23385700, PMID 23427844, PMID 23567060, PMID 23643652, PMID 23756884, PMID 23771276, PMID 23953215, PMID 24110501, PMID 24168714, PMID 24235894, PMID 24247058, PMID 24269982, PMID 24392483, PMID 24596907, PMID 24635459, PMID 24785463, PMID 24843394, PMID 24864394, PMID 24923944, PMID 24942041, PMID 25004051, PMID 25191887, PMID 25283030, PMID 25329141, PMID 25363423, PMID 25416461, PMID 25440210, PMID 25512839
2019 (1), R01HD096331 (1), R21AT004469 (1), UL1TR001082 (1)