163 completed, 41 unknown, 22 recruiting, 19 terminated. 134 Not applicable, 32 Phase 4, 27 Phase 2, 20 Phase 3, 12 Phase 1.
Follow Panic Disorder: new trials by email Literature Review of Panic Disorder trials Research Report on Panic Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial to Evaluate the Efficacy and Safety of Meltz, a Digital Therapeutic Device, for Improving Panic Symptoms in Patients With Panic Disorder Meltz, Sham Application - Panic Disorder, Agoraphobia | Not applicable | Not yet recruiting | AIMNEXT | 120 | 2026-10-01 | 2026-10-23 |
| Non-Coding RNAs Gene Expression in Psychiatric Disorders Reverse Transcription Quantitative Polymerase Chain Reaction - Schizophrenia Disorders, Major Depression | Not yet recruiting | Carmen Concerto | 384 | 2026-09-01 | 2026-06-23 | |
| Serotonin Variants & Gut Microbiota in Mental Health SNP Genotyping and Gut Metagenomics - Major Depressive Disorder (MDD, Anxiety Disorder, Generalized | Not yet recruiting | Neurobiologix | 30 | 2026-07-01 | 2026-06-10 | |
| Efficacy of Expectancy Focused Exposure Therapy for Anxiety Disorders Expectancy Focused Exposure, Anxiety Focused Exposure - Anxiety Disorders, Panic Disorder | Not applicable | Recruiting | University of Chile | 203 | 2026-07-01 | 2026-08-07 |
| Psychoeducation Based on Acceptance and Commitment Therapy Acceptance and Commitment Therapy-Based Psychoeducation, control group - Panic Disorder | Not applicable | Completed | Muğla Sıtkı Koçman University | 50 | 2026-06-21 | 2026-10-13 |
| Testing a Precision Psychotherapy System for Low-income Patients Pre-treatment psychotherapy recommendations - Major Depressive Disorder, Dysthymic Disorder | Not applicable | Not yet recruiting | National Council of Scientific and Technical Research, Argentina | 111 | 2026-02-01 | 2021-11-18 |
| Stepped Care Treatment for Anxiety Resilience Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A) - Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD) | Not applicable | Recruiting | Andrew Wiese | 106 | 2026-01-05 | 2026-03-02 |
| Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders Internet-Delivered Cognitive Behavioral Therapy - ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Specific Phobia | Not applicable | Recruiting | Lund University | 48 | 2025-12-12 | 2026-02-20 |
| Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders H pylori stool test, Bacterial stool analysis - Anxiety, Panic Disorder | Completed | University of Toronto | 500 | 2025-12-10 | 2026-04-29 | |
| Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings. Team-delivered, exposure-based CBT - Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders | Not applicable | Recruiting | Bradley Hospital | 501 | 2025-11-01 | 2026-07-31 |
| Anxiety Skills Study Cognitive therapy, Behavioral therapy, Mindfulness-based therapy - Anxiety, Anxiety Acute | Not applicable | Recruiting | Ohio State University | 600 | 2025-10-20 | 2026-08-19 |
| Preoperative Pregabalin vs Gabapentin in Elderly Undergoing Surgry,Controlled Trial One hour prior to admission to the operating room, patients will receive the study medication (as premedication) by mouth with a sip of water; - Anxiety, Anxiety Disorder (Panic Disorder or GAD) | Not applicable | Not yet recruiting | Cairo University | 84 | 2025-09-15 | 2025-07-04 |
| Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety Disorders Metacognitive therapy (MCT), Unified protocol (UP) - Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD) | Not applicable | Not yet recruiting | Karolinska Institutet | 114 | 2025-08-01 | 2025-05-14 |
| IL-33, sST2, and CRP in Panic Disorder Panic Disorder | Completed | Elazığ Mental Health and Diseases Hospital | 71 | 2025-07-07 | 2026-10-26 | |
| Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy - Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence | Not applicable | Active not recruiting | Baylor College of Medicine | 174 | 2025-07-01 | 2026-07-30 |
| Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in Adults Dexmedetomidine, Placebo - Dexmedetomidine, Panic Attacks | Not applicable | Completed | Tongji University | 40 | 2025-06-26 | 2026-10-16 |
| Stepped Versus Stratified Care for Anxiety Disorders in Youth Internet-delivered cognitive-behavioral therapy, Personalized in-person cognitive-behavioral therapy - Social Anxiety Disorder, Separation Anxiety Disorder | Not applicable | Recruiting | Region Skane | 556 | 2025-06-19 | 2026-02-27 |
| Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method Mindful Self-Compassion - Anxiety Disorders, Generalized Anxiety Disorder | Not applicable | Recruiting | Georgetown University | 80 | 2025-06-01 | 2026-05-05 |
| Investigations of Factors Associated With Treatment Response and Prognosis in Anxiety Disorders Psychiatric scale assessments, VR-Based Behavioral Assessment, Brain MRI - Panic Disorder | Not yet recruiting | Kangbuk Samsung Hospital | 185 | 2025-05-15 | 2025-04-30 | |
| α-N-acetylgalactosaminidase Levels in Panic Disorder No intervention was assigned as part of the research protocol. - Panic Disorder | Completed | Elazığ Mental Health and Diseases Hospital | 66 | 2025-05-01 | 2026-06-29 |
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Anxiety Disorders (122) · Generalized Anxiety Disorder (106) · Phobia, Social (80) · Agoraphobia (48) · Depression (42) · Stress Disorders, Post-Traumatic (40) · Depressive Disorder, Major (32) · Obsessive-Compulsive Disorder (32) · Phobia, Specific (21) · Anxiety, Separation (13) · Mental Disorders (12) · Bipolar Disorder (10) · Dysthymic Disorder (10) · Alcoholism (9)
Mental Disorders (253) · Anxiety Disorders (143) · Phobic Disorders (89) · Behavior (58) · Mood Disorders (46) · Behavioral Symptoms (45) · Trauma and Stressor Related Disorders (40) · Stress Disorders, Traumatic (37) · Pathological Conditions, Signs and Symptoms (35) · Depressive Disorder (33) · Signs and Symptoms (23) · Nervous System Diseases (20) · Neurodevelopmental Disorders (20) · Pathologic Processes (19) · Chemically-Induced Disorders (14)
Cognitive Behavioral Therapy (34) · Paroxetine (15) · Sertraline (9) · Alprazolam (8) · Exercise (7) · Cycloserine (5) · Escitalopram (5) · Behavior Therapy (4) · Risperidone (4) · Waiting Lists (4) · Bibliotherapy (3) · Biofeedback, Psychology (3) · Clonazepam (3) · Duloxetine Hydrochloride (3) · Implosive Therapy (3)
National Institute of Mental Health (NIMH) (9) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (7) · Massachusetts General Hospital (6) · Karolinska Institutet (5) · Universidade Federal do Rio de Janeiro (5) · VA Office of Research and Development (5) · Boston University Charles River Campus (4) · Charite University, Berlin, Germany (4) · Georgetown University (4) · Laureate Institute for Brain Research, Inc. (4) · Samsung Medical Center (4) · University of Pittsburgh (4) · University of Texas at Austin (4) · Amager Hospital (3) · Baylor College of Medicine (3)
United States (108) · Canada (21) · Sweden (13) · Germany (10) · Turkey (Türkiye) (9) · United Kingdom (8) · Brazil (7) · South Korea (7) · Netherlands (6) · Norway (6) · Romania (5) · Denmark (4) · Spain (4) · Taiwan (4) · China (3)
Michael Van Ameringen, MD, FRCPC (4) · Ellen Teng, PhD (3) · Anca Dobrean, Ph.D. (2) · Andreas Frick, PhD (2) · Antonio E Nardi, MD (2) · Arun Ravindran, MD, PhD (2) · Bruce L. Rollman, MD, MPH (2) · Bum-Hee Yu, M.D., Ph.D. (2) · Daniel F Gros, PhD MA BS (2) · Daniel S Pine, M.D. (2) · Elizabeth Hoge, MD (2) · Ellen Teng, Ph.D (2) · Fong-Lin Jang, M.D. (2)
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R01MH059395 (2), 2016 (1), 2019 (1), 2023 (1), DP1MH116506 (1), K23MH001831 (1), K23MH001849 (1), K23MH133063 (1), P50MH077928 (1), R01HL133149 (1), R01MH045963 (1), R01MH045964 (1), R01MH045965 (1), R01MH045966 (1), R01MH065413 (1)