240 completed, 43 recruiting, 32 unknown, 19 terminated. 228 Not applicable, 49 Phase 2, 34 Phase 3, 24 Phase 4, 16 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Uncovering Neurocognitive Mechanisms and Enhancement of Exposure-based Fear Learning With Cognitive Training Cognitive training - Anxiety, Fear Extinction | Not applicable | Not yet recruiting | University of California, San Diego | 120 | 2027-01-01 | 2026-09-04 |
| Caplyta Versus Placebo for Adults With Social Anxiety Disorder Lumateperone 42 mg, Placebo - Social Anxiety Disorder (SAD) | Phase 4 | Recruiting | Jason Careri | 40 | 2026-09-10 | 2026-09-15 |
| Efficacy of Expectancy Focused Exposure Therapy for Anxiety Disorders Expectancy Focused Exposure, Anxiety Focused Exposure - Anxiety Disorders, Panic Disorder | Not applicable | Recruiting | University of Chile | 203 | 2026-07-01 | 2026-08-07 |
| Efficacy of Attention Bias Modification vs. Placebo for Social Anxiety Disorder Dot-Probe Attention Bias Modification (ABM), Placebo Training - Social Anxiety Disorder (SAD), Attention Bias Modification Treatment (ABMT) | Not applicable | Recruiting | Tel Aviv University | 90 | 2026-06-15 | 2026-06-24 |
| Safety Behavior Fading Versus Progressive Muscle Relaxation for Appearance Concerns Safety Behavior Fading for Appearance Concerns, Progressive Muscle Relaxation - Body Dysmorphic Disorder, Eating Disorders | Not applicable | Active not recruiting | Florida State University | 300 | 2026-05-29 | 2026-09-30 |
| Effectiveness of an AI-Integrated Proactive Thought Control Intervention for Young Adults With Social Anxiety Disorder AI-Proactive thought control, Cognitive Behavior Therapy, Active Control - Social Anxiety Disorder (SAD) | Not applicable | Completed | Farah Shahzadi | 75 | 2026-03-14 | 2026-09-09 |
| Brief Interpretation Bias Modification for Social Anxiety Disorder in Pakistani Young Adults: An Experimental Evaluation WSAP-based interpretation bias modification, WSAP interpretation control condition - Social Anxiety Disorder, Interpretation Bias | Not applicable | Not yet recruiting | Ather Mujitaba | 130 | 2026-02-01 | 2026-02-12 |
| Testing a Precision Psychotherapy System for Low-income Patients Pre-treatment psychotherapy recommendations - Major Depressive Disorder, Dysthymic Disorder | Not applicable | Not yet recruiting | National Council of Scientific and Technical Research, Argentina | 111 | 2026-02-01 | 2021-11-18 |
| Metacognitive Therapy Compared to Cognitive-behavioral Therapy Transdiagnostic metacognitive therapy, Disorder-specific cognitive-behavioral therapy - Generalized Anxiety Disorder, Social Anxiety Disorder | Not applicable | Recruiting | Karolinska Institutet | 30 | 2026-01-28 | 2026-08-18 |
| Stepped Care Treatment for Anxiety Resilience Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A) - Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD) | Not applicable | Recruiting | Andrew Wiese | 106 | 2026-01-05 | 2026-03-02 |
| An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms Digital software application for cognitive performance and activity measurement (QbMobile, investigational device) - Bi-Polar Disorder, Autism Spectrum Disorder (ASD) | Suspended | Qbtech AB | 300 | 2026-01-01 | 2026-09-25 | |
| Online Radical Acceptance Intervention for Social Anxiety Disorder Radical Acceptance, Relaxation Skills - Social Anxiety Disorder (SAD) | Not applicable | Recruiting | University of Haifa | 100 | 2025-12-16 | 2026-05-06 |
| Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders Internet-Delivered Cognitive Behavioral Therapy - ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Specific Phobia | Not applicable | Recruiting | Lund University | 48 | 2025-12-12 | 2026-02-20 |
| Intermittent Theta Burst Stimulation of the Prefrontal Cortex in Social Anxiety Disorder Active Intermittent Theta-Burst Stimulation (iTBS), Sham Intermittent Theta-Burst Stimulation (iTBS) - Social Anxiety Disorder (SAD) | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 100 | 2025-12-09 | 2026-03-12 |
| A Study of NTX-1472 in Social Anxiety Disorder NTX-1472, Placebo - Social Anxiety Disorder (SAD) | Phase 2 | Recruiting | Newleos Therapeutics, Inc. | 100 | 2025-12-09 | 2026-07-09 |
| Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings. Team-delivered, exposure-based CBT - Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders | Not applicable | Recruiting | Bradley Hospital | 501 | 2025-11-01 | 2026-07-31 |
| Virtual Reality Based Cognitive Behavioral Therapy for Social Anxiety Among Youths in Hong Kong VR intervention - Social Anxiety Disorder (SAD), Social Phobia | Not applicable | Not yet recruiting | Hong Kong Shue Yan University | 90 | 2025-11-01 | 2025-09-15 |
| Anxiety Skills Study Cognitive therapy, Behavioral therapy, Mindfulness-based therapy - Anxiety, Anxiety Acute | Not applicable | Recruiting | Ohio State University | 600 | 2025-10-20 | 2026-08-19 |
| Using TMS to Understand Neural Processes of Social Motivation TMS - Social Avoidant Behavior, Major Depressive Disorder | Not applicable | Recruiting | Auburn University | 40 | 2025-09-30 | 2026-03-03 |
| Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder VQW-765, Placebo - Social Anxiety Disorder (SAD) | Phase 3 | Active not recruiting | Vanda Pharmaceuticals | 500 | 2025-09-22 | 2026-08-17 |
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Anxiety Disorders (132) · Generalized Anxiety Disorder (119) · Panic Disorder (80) · Obsessive-Compulsive Disorder (43) · Anxiety, Separation (40) · Agoraphobia (39) · Stress Disorders, Post-Traumatic (32) · Phobia, Specific (30) · Depression (25) · Depressive Disorder, Major (25) · Phobic Disorders (24) · Dysthymic Disorder (12) · Psychological Well-Being (10) · Autism Spectrum Disorder (9)
Mental Disorders (357) · Phobic Disorders (339) · Anxiety Disorders (231) · Neurodevelopmental Disorders (56) · Behavior (43) · Mood Disorders (38) · Trauma and Stressor Related Disorders (34) · Stress Disorders, Traumatic (31) · Behavioral Symptoms (26) · Depressive Disorder (26) · Pathological Conditions, Signs and Symptoms (16) · Chemically-Induced Disorders (15) · Child Development Disorders, Pervasive (15) · Signs and Symptoms (13) · Nervous System Diseases (12)
Cognitive Behavioral Therapy (47) · Therapeutics (11) · Paroxetine (10) · Sertraline (10) · Implosive Therapy (8) · Quetiapine Fumarate (6) · Virtual Reality Exposure Therapy (6) · Cannabidiol (5) · Cycloserine (5) · Waiting Lists (5) · Dexetimide (4) · Escitalopram (4) · Exercise (4) · Sugars (4) · Autogenic Training (3)
GlaxoSmithKline (11) · Karolinska Institutet (9) · Tel Aviv University (9) · Florida State University (7) · Massachusetts General Hospital (7) · University of California, Los Angeles (7) · University of South Florida (7) · University of Texas at Austin (7) · New York State Psychiatric Institute (6) · University of Michigan (6) · VistaGen Therapeutics, Inc. (6) · University of California, San Diego (5) · Babes-Bolyai University (4) · Baylor College of Medicine (4) · Boston University Charles River Campus (4)
United States (185) · Canada (29) · Sweden (25) · Israel (14) · Germany (13) · United Kingdom (11) · Denmark (10) · Norway (10) · Romania (7) · China (5) · Netherlands (5) · Turkey (Türkiye) (5) · Brazil (4) · Japan (4) · Pakistan (4)
Yair Bar-Haim, PhD (7) · Michael Van Ameringen, MD, FRCPC (6) · Arun Ravindran, MD, PhD (4) · Eric A Storch, Ph.D. (4) · Franklin Schneier, MD (3) · Per Carlbring, PhD (3) · Per Carlbring, Professor (3) · Angela Fang, PhD (2) · Daniel F Gros, PhD MA BS (2) · Diana Koszycki, PhD (2) · Elizabeth Hoge, MD (2) · Gerhard Andersson, Professor (2) · Gisele G Manfro, MD, PhD (2) · Jasper Smits, Ph.D. (2)
PMID 42743597, PMID 24098630, PMID 2885745, PMID 31430688, PMID 34693989, PMID 38754336, PMID 40208666, PMID 10052767, PMID 12694427, PMID 14584861, PMID 15157814, PMID 15330942, PMID 15341364, PMID 15562916, PMID 15691340, PMID 16268999, PMID 16540816, PMID 17539717, PMID 17891261, PMID 18030084, PMID 18974308, PMID 19157776, PMID 19212970, PMID 19222311, PMID 19508270, PMID 19829198, PMID 20013046, PMID 20018493, PMID 20046862, PMID 20051130, PMID 20146834, PMID 20206470, PMID 20483968, PMID 21367351, PMID 21391024, PMID 21464362, PMID 21483704, PMID 21676694, PMID 21762829, PMID 22122292, PMID 22152230, PMID 22233247, PMID 22245618, PMID 22304968, PMID 22320999, PMID 22348135, PMID 22362158, PMID 22404963, PMID 22420873, PMID 22647314
P50MH080215 (2), R01MH075889 (2), R01MH076074 (2), R34MH073004 (2), R34MH100468 (2), 2014 (1), 2016 (1), 2018 (1), 2023 (1), 2025 (1), F32MH129076 (1), K01MH072952 (1), K23DA048181 (1), K23MH076198 (1), K23MH133063 (1)