28 completed, 5 terminated, 5 unknown, 1 active not recruiting. 40 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 40 | Completed 28, Terminated 5, Unknown 5, Active not recruiting 1, Withdrawn 1 |
Follow Obsessive-Compulsive Disorder: new trials by email Literature Review of Obsessive-Compulsive Disorder trials Research Report on Obsessive-Compulsive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NAC for Treatment-Resistant OCD and Other Related Disorders N-Acetylcysteine Tablets, Placebo Oral Tablet - Obsessive Compulsive Disorder (OCD) | Phase 4 | Active not recruiting | Guangdong Provincial People's Hospital | 90 | 2022-06-22 | 2025-09-03 |
| Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome Guanfacine Extended Release, Placebo - Prader-Willi Syndrome, Aggression | Phase 4 | Completed | Maimonides Medical Center | 15 | 2020-12-17 | 2024-08-19 |
| Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS Naproxen Sodium, Placebo - PANDAS, Anxiety Disorder | Phase 4 | Terminated | Massachusetts General Hospital | 2 | 2020-10-20 | 2026-05-20 |
| Predicting Treatment Response in Patients With OCD selective serotonin reuptake inhibitor - Obsessive-Compulsive Disorder | Phase 4 | Completed | University of Sao Paulo | 250 | 2018-10-10 | 2024-02-28 |
| Probiotic Treatment in Adult Obsessive-Compulsive Disorder Probiotic Formula (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175), Placebo - Obsessive-Compulsive Disorder | Phase 4 | Terminated | McMaster University | 15 | 2018-09-01 | 2021-09-10 |
| A Study to Evaluate the Benefit of Octagam 5%® in Subjects With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) IVIG - Pediatric Acute-Onset Neuropsychiatric Syndrome, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections | Phase 4 | Unknown | IMMUNOe Research Centers | 21 | 2017-11-24 | 2019-11-19 |
| Effects of Ondansetron in Obsessive-compulsive and Tic Disorders Ondansetron, Placebo - Obsessive-Compulsive Disorder, Tic Disorders | Phase 4 | Completed | NYU Langone Health | 110 | 2017-06-16 | 2024-05-03 |
| Fear Conditioned Response in Healthy Subjects and in OCD Patients Pre and Post Treatment With Sertraline. Sertraline Hydrochloride - Obsessive-Compulsive Disorder | Phase 4 | Completed | University of Sao Paulo | 69 | 2016-12-01 | 2021-04-27 |
| Brief Intervention for OCD Fears Propanolol, Placebo - Obsessive-compulsive Disorder | Phase 4 | Withdrawn | New York State Psychiatric Institute | 2016-06-01 | 2023-04-18 | |
| Translational Approach to the Understanding and Treatment of Obsessive-Compulsive Disorder (OCD). Can D-Cycloserine Enhance and Stabilize the Treatment-response in Relapsed and Non-responding OCD-patients? D-Cycloserine, Placebo - Obsessive-Compulsive Disorder | Phase 4 | Completed | Haukeland University Hospital | 163 | 2015-11-01 | 2021-02-11 |
| Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients Fluoxetine, Sertraline, Paroxetine - Obsessive-Compulsive Disorder, Anxiety Disorders | Phase 4 | Completed | Shanghai Mental Health Center | 78 | 2014-01-01 | 2022-09-09 |
| Methylphenidate Hydrochloride Controlled-Release Tablets Augmentation Strategy for Patients With Obsessive Compulsive Disorder Fluvoxamine+Methylphenidate hydrochloride, Fluvoxamine+sugar pill - Obsessive Compulsive Disorder | Phase 4 | Completed | Guangdong Provincial People's Hospital | 60 | 2013-10-01 | 2015-10-23 |
| D-Cycloserine as an Adjunct to Internet-CBT for OCD D-Cycloserine, Placebo - Obsessive-compulsive Disorder | Phase 4 | Completed | Christian Rück | 128 | 2012-08-01 | 2016-12-12 |
| Deep Brain Stimulation for Obsessive Compulsive Disorder (OCD PMCF) Reclaim® Deep Brain Stimulation - Obsessive Compulsive Disorder | Phase 4 | Completed | MedtronicNeuro | 32 | 2010-04-01 | 2018-01-23 |
| Ondansetron Augmentation in Treatment-resistant OCD Ondansetron - Obsessive Compulsive Disorder | Phase 4 | Completed | Institute of Neuroscience, Florence, Italy | 21 | 2009-12-01 | 2011-02-24 |
| Effectiveness of Sertraline and Cognitive Behavioral Therapy in Treating Pediatric Obsessive-Compulsive Disorder Regular Titration, Placebo, Slow Titration - Obsessive-Compulsive Disorder | Phase 4 | Completed | University of Florida | 56 | 2009-02-01 | 2013-03-12 |
| A Study of Pregabalin (Lyrica) Augmentation in Serotonin Reuptake Inhibitor-Refractory Obsessive Compulsive Disorder pregabalin, Placebo - Obsessive-Compulsive Disorder | Phase 4 | Completed | McMaster University | 15 | 2009-01-01 | 2019-06-18 |
| Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD) Luvox CR, Behavioral Therapy - Obsessive Compulsive Disorder | Phase 4 | Unknown | Rogers Center for Research & Training, Inc. | 50 | 2008-09-01 | 2008-09-04 |
| Comparison of Effects Between Conventional Dose and High Dose Escitalopram on Clinical Improvement in Patients With Obsessive-compulsive Disorder escitalopram - Obsessive Compulsive Disorder | Phase 4 | Completed | Seoul National University Hospital | 176 | 2008-09-01 | 2011-08-08 |
| Ondansetron in Treatment Resistant Obsessive Compulsive Disorder (OCD) ondansetron - Obsessive Compulsive Disorder | Phase 4 | Completed | Institute of Neuroscience, Florence, Italy | 14 | 2008-03-01 | 2011-02-24 |
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Anxiety Disorders (6) · Trichotillomania (3) · Autoimmune Diseases (2) · Disruptive, Impulse Control, and Conduct Disorders (2) · Excoriation Disorder (2) · Mental Disorders (2) · Panic Disorder (2) · Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (2) · Tic Disorders (2) · Tourette Syndrome (2) · Abnormalities, Multiple (1) · Aggression (1) · Agoraphobia (1) · Alcoholism (1)
Mental Disorders (38) · Anxiety Disorders (34) · Neurodevelopmental Disorders (5) · Behavior (3) · Central Nervous System Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Disruptive, Impulse Control, and Conduct Disorders (3) · Movement Disorders (3) · Nervous System Diseases (3) · Basal Ganglia Diseases (2) · Behavioral Symptoms (2) · Brain Diseases (2) · Genetic Diseases, Inborn (2) · Heredodegenerative Disorders, Nervous System (2)
Fluoxetine (5) · Sertraline (5) · Escitalopram (4) · Dexetimide (3) · Fluvoxamine (3) · Ondansetron (3) · Sugars (3) · Behavior Therapy (2) · Citalopram (2) · Clomipramine (2) · Cycloserine (2) · Paroxetine (2) · Quetiapine Fumarate (2) · Selective Serotonin Reuptake Inhibitors (2) · Topiramate (2)
Massachusetts General Hospital (6) · University of Sao Paulo (5) · McMaster University (3) · Guangdong Provincial People's Hospital (2) · Hamilton Health Sciences Corporation (2) · Institute of Neuroscience, Florence, Italy (2) · University of Florida (2) · Butler Hospital (1) · Christian Rück (1) · Creighton University (1) · Geha Mental Health Center (1) · Haukeland University Hospital (1) · IMMUNOe Research Centers (1) · Maimonides Medical Center (1) · MedtronicNeuro (1)
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Michael Van Ameringen, MD, FRCPC (3) · Darin D Dougherty, MD (2) · Juliana B Diniz, MD (2) · Stefano Pallanti, MD (2) · Andreas Wahl-Kordon, MD (1) · Antonio Higueras, MD (1) · Benjamin D. Greenberg, MD, PhD (1) · Bjarne Hansen (1) · Blair Simpson, MD (1) · Cristina B Silva, Psychologist (1) · Dan Stein (1) · Deepan Singh, MD (1) · Diana Radu-Djurfeldt (1) · Emily Stern, PhD (1)
PMID 19578654, PMID 34582562, PMID 13638508, PMID 14399272, PMID 19422759, PMID 19958042, PMID 20441724, PMID 20579510, PMID 20816027, PMID 21586916, PMID 21907540, PMID 22020357, PMID 22841131, PMID 23031804, PMID 23128051, PMID 23948637, PMID 24184429, PMID 25535011, PMID 25637377, PMID 25970252, PMID 26495770, PMID 2684084, PMID 32789516, PMID 33601937, PMID 38689256, PMID 40133857, PMID 41068703, PMID 41425659, PMID 444788, PMID 8290681
2005 (2), R01MH045802 (1), R01MH078594 (1), U01MH076179 (1)