23 completed, 5 unknown, 2 terminated, 2 withdrawn. 34 Phase 3, 9 Phase 2.
Follow Obsessive-Compulsive Disorder: new trials by email Literature Review of Obsessive-Compulsive Disorder trials Research Report on Obsessive-Compulsive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors Memantine, ComB Behavioral Therapy - Skin-Picking, Trichotillomania (Hair-Pulling Disorder) | Phase 2 / Phase 3 | Active not recruiting | University of Chicago | 26 | 2023-08-02 | 2026-07-07 |
| Ventral Capsulotomy for Intractable OCD Laser Interstitial Thermal Therapy - Obsessive-Compulsive Disorder | Phase 3 | Enrolling by invitation | Butler Hospital | 50 | 2022-06-21 | 2023-01-26 |
| Memantine for Refractory OCD Patients Memantine Oral Tablet, Placebo - Obsessive-Compulsive Disorder | Phase 3 | Unknown | University of Roma La Sapienza | 20 | 2021-09-01 | 2021-08-20 |
| Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder Troriluzole (BHV-4157) - Obsessive Compulsive Disorder | Phase 3 | Terminated | Biohaven Pharmaceuticals, Inc. | 772 | 2021-03-30 | 2026-02-25 |
| A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder Troriluzole, Placebo - Obsessive-Compulsive Disorder | Phase 3 | Completed | Biohaven Pharmaceuticals, Inc. | 589 | 2021-01-29 | 2026-05-22 |
| Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder Troriluzole, Placebo - Obsessive-Compulsive Disorder | Phase 3 | Completed | Biohaven Pharmaceuticals, Inc. | 456 | 2020-12-22 | 2026-01-07 |
| Vortioxetine for the Treatment of Hoarding Disorder Vortioxetine Tablets - Hoarding Disorder | Phase 3 | Withdrawn | Noam Soreni | 2019-08-01 | 2024-02-02 | |
| Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors Dronabinol, Placebo - Trichotillomania, Skin-Picking | Phase 2 / Phase 3 | Completed | University of Chicago | 50 | 2018-10-01 | 2022-06-02 |
| Tolcapone in Obsessive Compulsive Disorder Tolcapone 200 MG - Obsessive-Compulsive Disorder | Phase 2 / Phase 3 | Completed | University of Chicago | 20 | 2018-03-20 | 2022-04-07 |
| Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder Troriluzole, Placebo - Obsessive-Compulsive Disorder | Phase 2 / Phase 3 | Completed | Biohaven Pharmaceuticals, Inc. | 426 | 2017-12-19 | 2026-01-22 |
| Pharmacogenetics in Primary Care Psychotropics Pharmacogenetic testing - Depression, Obsessive-Compulsive Disorder | Phase 3 | Unknown | University of Arizona | 130 | 2017-08-15 | 2017-07-28 |
| Novel Deep Brain Stimulation in Ventral Capsule and Stratum for Refractory Obsessive-Compulsive Disorder deep brain stimulation system - Obsessive-Compulsive Disorder | Phase 2 / Phase 3 | Unknown | Ruijin Hospital | 8 | 2015-10-01 | 2016-12-06 |
| Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation Transcranial Magentic Stimulation - Obsessive-Compulsive Disorder | Phase 3 | Unknown | Butler Hospital | 19 | 2015-06-01 | 2023-12-14 |
| Safety and Effectiveness of Capsulotomy in Refractory OCD Anterior Capsulotomy - Obsessive-Compulsive Disorder | Phase 2 / Phase 3 | Unknown | Ruijin Hospital | 30 | 2015-04-01 | 2015-04-28 |
| China Refractory Obsessive-Compulsive Disorder Deep Brain Stimulation Study Bilateral Nucleus Accumbens DBS (Suzhou Sceneray), Sham Bilateral Nucleus Accumbens DBS - Obsessive Compulsive Disorder | Phase 2 / Phase 3 | Withdrawn | Ruijin Hospital | 2015-04-01 | 2016-12-06 | |
| A Phase 3 Study of Fluvoxamine (SME3110) in Pediatric/Adolescent Patients With Obsessive Compulsive Disorder Fluvoxamine maleate, Placebo - Obsessive Compulsive Disorder | Phase 3 | Completed | AbbVie | 38 | 2013-08-14 | 2017-12-04 |
| D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD) Cognitive-behavioral therapy, d-cycloserine, Pill placebo - Obsessive-compulsive Disorder | Phase 3 | Completed | University of South Florida | 142 | 2011-06-01 | 2018-01-23 |
| Deep Brain Stimulation and Obsessive-compulsive Disorder Deep Brain Stimulation (DBS) - Obsessive-Compulsive Disorder | Phase 3 | Completed | University Hospital, Bordeaux | 31 | 2011-04-04 | 2020-02-06 |
| Intravenous Immunoglobulin for PANDAS Gamunex Intravenous Immunoglobulin, Placebo - Obsessive-Compulsive Disorder, Children | Phase 3 | Completed | National Institute of Mental Health (NIMH) | 48 | 2011-01-01 | 2020-03-17 |
| Comparison of DBS Targets in Obsessive-compulsive Disorder Deep brain stimulation - Obsessive-Compulsive Disorder | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 8 | 2010-10-01 | 2016-05-18 |
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Anxiety Disorders (4) · Generalized Anxiety Disorder (4) · Anxiety, Separation (2) · Excoriation Disorder (2) · Phobia, Social (2) · Trichotillomania (2) · Asperger Syndrome (1) · Autistic Disorder (1) · Autoimmune Diseases (1) · Compulsive Behavior (1) · Depression (1) · Hoarding Disorder (1) · Obsessive Behavior (1) · Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (1)
Mental Disorders (34) · Anxiety Disorders (30) · Behavior (4) · Behavioral Symptoms (4) · Disruptive, Impulse Control, and Conduct Disorders (2) · Neurodevelopmental Disorders (2) · Phobic Disorders (2) · Self-Injurious Behavior (2) · Autism Spectrum Disorder (1) · Child Development Disorders, Pervasive (1) · Immune System Diseases (1) · Impulsive Behavior (1)
Cognitive Behavioral Therapy (6) · Fluvoxamine (3) · Memantine (3) · Relaxation Therapy (3) · Sertraline (3) · Behavior Therapy (2) · Counseling (2) · Cycloserine (2) · Deep Brain Stimulation (2) · Escitalopram (2) · Psychotherapy (2) · Citalopram (1) · Clomipramine (1) · Dronabinol (1) · Family Therapy (1)
Biohaven Pharmaceuticals, Inc. (4) · National Institute of Mental Health (NIMH) (3) · Ruijin Hospital (3) · University of Chicago (3) · University of South Florida (3) · Butler Hospital (2) · Duke University (2) · Rhode Island Hospital (2) · Abarbanel Mental Health Center (1) · AbbVie (1) · Assistance Publique - Hôpitaux de Paris (1) · AstraZeneca (1) · Massachusetts General Hospital (1) · Noam Soreni (1) · University Hospital, Bordeaux (1)
United States (21) · China (4) · Canada (3) · France (2) · Italy (2) · Netherlands (2) · Spain (2) · United Kingdom (2) · Germany (1) · Israel (1)
Bomin Sun, MD, PhD (2) · Alexander Bystritsky, MD (1) · Bomin Sun, MD,PhD (1) · Edna B. Foa, PhD (1) · Eric A Storch, Ph.D. (1) · Eric Storch, Ph.D. (1) · Eric Storch, PhD (1) · Gregory Chasson, PhD (1) · Herbert E Ward, MD (1) · Jennifer B. Freeman, PhD (1) · John C. Piacentini, PhD (1)
PMID 10465680, PMID 16490414, PMID 18090508, PMID 18356758, PMID 18356759, PMID 19183470, PMID 19204653, PMID 20855047, PMID 21934055, PMID 22024003, PMID 23063327, PMID 23357440, PMID 23525525, PMID 23774008, PMID 24759852, PMID 25457929, PMID 27166296, PMID 27663941, PMID 28412602, PMID 29100251, PMID 29233751, PMID 34582562, PMID 34825898, PMID 37166948, PMID 37243560
R01MH055121 (1), R01MH055126 (1), R01MH079217 (1), R10MH055121 (1), R21MH060669 (1)