39 completed, 5 unknown, 4 active not recruiting, 4 recruiting. 39 Not applicable, 8 Phase 2, 5 Phase 3, 3 Phase 1, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stepped Care Treatment for Anxiety Resilience Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A) - Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD) | Not applicable | Recruiting | Andrew Wiese | 106 | 2026-01-05 | 2026-03-02 |
| An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms Digital software application for cognitive performance and activity measurement (QbMobile, investigational device) - Bi-Polar Disorder, Autism Spectrum Disorder (ASD) | Suspended | Qbtech AB | 300 | 2026-01-01 | 2026-09-25 | |
| Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders Internet-Delivered Cognitive Behavioral Therapy - ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Specific Phobia | Not applicable | Recruiting | Lund University | 48 | 2025-12-12 | 2026-02-20 |
| Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings. Team-delivered, exposure-based CBT - Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders | Not applicable | Recruiting | Bradley Hospital | 501 | 2025-11-01 | 2026-07-31 |
| Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy - Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence | Not applicable | Active not recruiting | Baylor College of Medicine | 174 | 2025-07-01 | 2026-07-30 |
| Stepped Versus Stratified Care for Anxiety Disorders in Youth Internet-delivered cognitive-behavioral therapy, Personalized in-person cognitive-behavioral therapy - Social Anxiety Disorder, Separation Anxiety Disorder | Not applicable | Recruiting | Region Skane | 556 | 2025-06-19 | 2026-02-27 |
| Schema Therapy for Treatment-resistant Anxiety Disorders Individual Schema Therapy, TAU - Anxiety Disorders | Not applicable | Not yet recruiting | Amsterdam UMC, location VUmc | 172 | 2024-09-01 | 2024-03-07 |
| Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA) Cognitive Behavioral Therapy, Treatment as Usual - Anxiety, Autism Spectrum Disorder | Not applicable | Completed | Baylor College of Medicine | 32 | 2024-01-15 | 2026-09-02 |
| Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship - Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood | Not applicable | Active not recruiting | Baylor College of Medicine | 100 | 2023-09-14 | 2026-09-02 |
| Effects on Recovery of Children of Intravenous Formulation of Fentanyl Citrate and Midazolam Orally for Premedication Fentanyl Citrate - Separation Anxiety | Not applicable | Active not recruiting | Alexandria University | 60 | 2022-03-01 | 2024-11-29 |
| Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder Standard SPACE, Bibliotherapy, low therapist contact SPACE - Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood | Not applicable | Completed | Baylor College of Medicine | 68 | 2021-07-01 | 2025-03-04 |
| S-ketamin Premedication in Pediatric EENT Surgery S-ketamine 0.3, S-ketamine 0.5, S-ketamine 2 - Emotions, Separation Anxiety | Early Phase 1 | Completed | Eye & ENT Hospital of Fudan University | 320 | 2021-03-01 | 2022-04-27 |
| Partners in Caring for Anxious Youth Cognitive Behavioral Therapy (CBT), Combination therapy (COMB) - Anxiety, Separation, Anxiety, Generalized | Phase 3 | Active not recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 468 | 2021-02-09 | 2026-07-01 |
| Virtual Reality System for Anxiety and OCD VR System, Control - Anxiety, Obsessive-Compulsive Disorder | Not applicable | Completed | Minnesota HealthSolutions | 45 | 2020-11-01 | 2024-10-15 |
| Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety Cognitive Bias Modification for Interpretations (CBM-I), Interpretation Control Condition (ICC) - Anxiety Disorders | Not applicable | Completed | University of Denver | 50 | 2020-06-20 | 2025-03-05 |
| Youth Mayo Clinic Anxiety Coach Randomized Controlled Trial Mayo Clinic Anxiety Coach, Treatment as Usual - Anxiety | Not applicable | Completed | Stephen Whiteside | 145 | 2019-01-01 | 2021-03-29 |
| Improving Access to Child Anxiety Treatment Exposure Therapy - Obsessive-Compulsive Disorder, Anxiety Disorders | Not applicable | Unknown | Bradley Hospital | 379 | 2018-07-01 | 2022-08-03 |
| Comparison of Virtual Reality to Tablet-based Distraction in Children Separation Anxiety - Anxiety, Separation | Not applicable | Completed | Loma Linda University | 94 | 2018-04-30 | 2021-03-15 |
| Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD Virtual Reality - Anxiety, Obsessive Compulsive Disorder | Not applicable | Completed | Mayo Clinic | 40 | 2017-08-01 | 2018-11-13 |
| Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety Cognitive Behavioral Therapy, Relaxation Therapy - Anxiety Disorders, Social Anxiety Disorder | Not applicable | Completed | University of Michigan | 207 | 2016-12-01 | 2021-12-20 |
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Generalized Anxiety Disorder (48) · Phobia, Social (40) · Anxiety Disorders (37) · Obsessive-Compulsive Disorder (19) · Phobia, Specific (14) · Panic Disorder (13) · Phobic Disorders (11) · Agoraphobia (9) · Asperger Syndrome (5) · Autistic Disorder (5) · Autism Spectrum Disorder (3) · Mutism (3) · Attention Deficit Disorder with Hyperactivity (1) · Bipolar Disorder (1)
Mental Disorders (59) · Neurodevelopmental Disorders (59) · Phobic Disorders (31) · Anxiety Disorders (22) · Child Development Disorders, Pervasive (7) · Neurologic Manifestations (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Autism Spectrum Disorder (4) · Nervous System Diseases (4) · Neurobehavioral Manifestations (4) · Communication Disorders (3) · Language Disorders (3) · Speech Disorders (3) · Aberrant Motor Behavior in Dementia (1)
Cognitive Behavioral Therapy (12) · Therapeutics (8) · Sertraline (3) · Bibliotherapy (2) · Fluvoxamine (2) · Midazolam (2) · Psychotherapy (2) · Behavior Therapy (1) · Combined Modality Therapy (1) · Counseling (1) · Dexetimide (1) · Dexmedetomidine (1) · Esketamine (1) · Exercise (1) · Fentanyl (1)
University of South Florida (7) · Baylor College of Medicine (4) · National Institute of Mental Health (NIMH) (3) · Bradley Hospital (2) · Mayo Clinic (2) · New York State Psychiatric Institute (2) · Stephen Whiteside (2) · University of California, Los Angeles (2) · University of California, San Diego (2) · University of Michigan (2) · University of Pittsburgh (2) · Weill Medical College of Cornell University (2) · Alexandria University (1) · Amsterdam UMC, location VUmc (1) · Andrew Wiese (1)
United States (42) · Sweden (3) · Israel (2) · Norway (2) · Australia (1) · Brazil (1) · Canada (1) · China (1) · Egypt (1) · Hong Kong (1) · South Korea (1) · Switzerland (1) · Turkey (Türkiye) (1)
Eric A Storch, Ph.D. (4) · John Walkup, MD (2) · Neal D Ryan, MD (2) · Stephen Whiteside, Ph.D., L.P. (2) · Ahmed S. Shehab (1) · Amir Levine (1) · Bridget Biggs, PhD (1) · Daniel S Pine, M.D. (1) · Denise A Chavira, PhD (1) · Denise A. Chavira, PhD (1) · Ecder Ozenc (1) · Einar Heiervang, MD (1) · Elizabeth Ghazal, MD (1) · Eva Serlachius, MD, PhD (1) · Franklin Schneier, MD (1)
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P50MH080215 (2), R34MH100468 (2), K01MH072952 (1), K23MH103555 (1), R01MH086517 (1), R01MH107419 (1), R34MH090149 (1), R61MH121552 (1), U01MH064089 (1)