482 completed, 90 terminated, 85 recruiting, 57 withdrawn. 392 Not applicable, 114 Phase 2, 85 Phase 1, 35 Phase 3, 35 Phase 4.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Improved Vagal Function on Periaqueductal Gray Connectivity breathing exercise training - Postural Tachycardia Syndrome | Not applicable | Not yet recruiting | Virginia Commonwealth University | 12 | 2028-01-01 | 2026-09-16 |
| Using Apollo Neuro in Autistic Children With Self-Injurious Behavior Apollo Neuro device - Self-Injurious Behavior, Autism Spectrum Disorder | Not applicable | Not yet recruiting | Virginia Commonwealth University | 18 | 2026-12-01 | 2026-08-17 |
| EMBRACE (EMPA in BReast Cancer for Activity and Cardiac ProtEction) Empagliflozin - Breast Cancer, Supportive Care in Cancer | Phase 2 | Not yet recruiting | Virginia Commonwealth University | 10 | 2026-12-01 | 2026-10-20 |
| TENS of Auricular Vagal Nerve for Radiation Necrosis Transcutaneous auricular vagal nerve stimulation (taVNS), Sham - Radiation Necrosis, Cerebral Edema | Not applicable | Not yet recruiting | Virginia Commonwealth University | 40 | 2026-11-30 | 2026-09-04 |
| Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain Injury Acute Brain Injury, Traumatic Brain Injury | Not yet recruiting | Virginia Commonwealth University | 220 | 2026-11-30 | 2026-08-19 | |
| Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening Changes in CRC screening awareness and intentions - Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening | Not applicable | Not yet recruiting | Virginia Commonwealth University | 30 | 2026-11-30 | 2026-10-21 |
| Enhancing an Existing Prevention Strategy to Reduce Intentional Firearm Injuries Among High-risk Youth (Phase 1) Establish an advisory board of high-risk youth, Feedback and advice sessions, Youth advisory board training - Prevention | Not applicable | Not yet recruiting | Virginia Commonwealth University | 45 | 2026-10-30 | 2026-09-03 |
| FIQS Dissemination and Implementation Text-Only Enrollment Strategy, Text Plus In-Person Enrollment Strategy, Anonymous Safety Reporting with Impact Website - Inpatient Experience Survey Administration, Inpatient Experience Survey Response | Not applicable | Not yet recruiting | University of California, San Francisco | 21800 | 2026-10-19 | 2026-10-13 |
| Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1) Extension DM1, Myotonic Dystrophy | Recruiting | Virginia Commonwealth University | 1000 | 2026-10-15 | 2026-10-16 | |
| Cemiplimab +/- Fianlimab Post Y90 Radioembolization in Patients With Hepatocellular Carcinoma Arm 1 cemiplimab, Arm 2 cemiplimab and fianlimab - Hepatocellular Carcinoma | Phase 1 | Withdrawn | Virginia Commonwealth University | 2026-10-01 | 2026-09-14 | |
| Open-label Feasibility Trial of HD-tDCS During Cognitive Behavioral Therapy for Cocaine Use Disorder High Definition Transcranial Direct Current Stimulation - Cocaine Use Disorder | Not applicable | Recruiting | Virginia Commonwealth University | 36 | 2026-10-01 | 2026-09-28 |
| Metronomic Decitabine-Cedazuridine and Venetoclax in R/R AML, HR-MDS, HR/AP MPN Decitabine-cedazuridine plus venetoclax (DEC-C+VEN), Azacitidine plus venetoclax (AZA+VEN) - Relapsed / Refractory AML, High Risk Myelodysplastic Syndrome | Phase 2 | Recruiting | Virginia Commonwealth University | 40 | 2026-09-16 | 2026-09-21 |
| Colon Health Champion Program Intervention Arm: Colon Health Champions (CHC) Program - Colorectal Cancer, CRC | Not applicable | Not yet recruiting | Virginia Commonwealth University | 29 | 2026-09-10 | 2026-09-01 |
| Southeastern ATTR Amyloidosis Consortium: SEATTRAC Family Registry Registry - Amyloidosis, Hereditary | Not yet recruiting | Virginia Commonwealth University | 1000 | 2026-09-01 | 2026-08-12 | |
| Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD) Transcranial Doppler (TCD) examination - Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke | Not yet recruiting | Virginia Commonwealth University | 100 | 2026-09-01 | 2026-09-14 | |
| Quit and Screen Project Quit and Screen Project training, G02 (Global Knowledge Center for Lung Cancer) Lung Cancer Screening training - Knowledge, Attitudes | Not applicable | Not yet recruiting | University of Arkansas | 300 | 2026-09-01 | 2026-04-13 |
| Single FrAction Interstitial BreaSt BracHytherApy Partial Breast Irradiation - Breast Cancer | Phase 2 | Not yet recruiting | Virginia Commonwealth University | 134 | 2026-09-01 | 2026-06-18 |
| Sacituzumab Tirumotecan in Pts w/ NEPC After Progression on Prior Chemotherapy Sacituzumab Tirumotecan - Prostate Cancer, Neuroendocrine Prostate Cancer (NEPC) | Phase 2 | Not yet recruiting | Virginia Commonwealth University | 20 | 2026-08-31 | 2026-08-24 |
| Biomarker-Guided Mycophenolate Mofetil Elimination in Low-Risk Older Adult Kidney Transplant Recipients Tacrolimus (Kidney transplant maintenance immunosuppression), Mycophenoate Mofetil, Prednisone (SOC arm) - Kidney Transplant Recipient | Early Phase 1 | Not yet recruiting | Virginia Commonwealth University | 20 | 2026-08-31 | 2026-09-08 |
| Safety and Tolerability Study of VVZ-2471 in Healthy Volunteers Placebo pills for 14-day intervention, VVZ-2471 for 14-day intervention - Healthy Controls | Phase 1 | Recruiting | Virginia Commonwealth University | 60 | 2026-08-28 | 2026-09-01 |
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Antonio Abbate, MD, PhD (12) · Alison Breland, PhD (10) · Frederick G Moeller, MD (8) · Nicholas Johnson, MD (6) · Ryan Garten, PhD (6) · Steven Grant, MD (6) · Andrew Poklepovic, MD (5) · Ashlee Loughan, PhD (5) · Benjamin Van Tassell, PharmD (5) · Bryant Tran, MD (5) · Jeffrey S Kreutzer, PhD (5) · Jessica G LaRose, PhD (5) · Melanie K Bean, PhD (5) · Nicholas Thomson (5) · Andrew S. Poklepovic, MD (4)
PMID 39531530, PMID 22541178, PMID 24212451, PMID 25482680, PMID 27154907, PMID 38016623, PMID 38404649, PMID 10559801, PMID 11460821, PMID 1163358, PMID 11981209, PMID 12063573, PMID 12075174, PMID 12559191, PMID 12796570, PMID 14691697, PMID 14736587, PMID 15082974, PMID 1519574, PMID 15273547, PMID 15481300, PMID 15756392, PMID 15920681, PMID 16018857, PMID 16353506, PMID 16633006, PMID 16785215, PMID 16787132, PMID 16818482, PMID 16925280, PMID 16925335, PMID 16925336, PMID 17020988, PMID 17116551, PMID 1733136, PMID 17386394, PMID 17562118, PMID 17567540, PMID 17903772, PMID 17905334, PMID 17921033, PMID 18065289, PMID 18195316, PMID 18471729, PMID 18492267, PMID 18512045, PMID 18929981, PMID 18929990, PMID 18996764, PMID 18997679
P30CA016059 (25), U54DA036105 (10), U54DA038999 (4), P30NR011403 (3), P50DA009262 (3), U54HD034449 (3), K23AA000222 (2), P20DA024157 (2), P50MD017319 (2), R01DA026091 (2), R01DK132373 (2), R01HD035629 (2), R21AA026681 (2), U01DK061713 (2), U01DK061718 (2)