15 completed, 5 terminated, 2 recruiting, 2 withdrawn. 10 Not applicable, 6 Phase 4, 5 Phase 2, 4 Phase 3, 2 Early Phase 1.
Follow Narcotic Use: new trials by email Literature Review of Narcotic Use trials Research Report on Narcotic Use
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion Exparel, Bupivacain - Back Pain, Surgery-Complications | Phase 2 / Phase 3 | Enrolling by invitation | Foundation for Orthopaedic Research and Education | 76 | 2024-04-30 | 2026-09-09 |
| Duloxetine Impact on Postoperative Pain Control and Outcomes Duloxetine 60 MG, Placebo - Acute Post-operative Pain, Chronic Post Operative Pain | Phase 2 | Terminated | Scripps Health | 17 | 2023-05-30 | 2025-05-04 |
| Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years NIPE monitor, Control - Post Operative Pain, Analgesia | Not applicable | Completed | Khon Kaen University | 70 | 2023-03-10 | 2024-04-23 |
| Efficacy of External Oblique Intercostal Block in Laparoscopic Bariatric Surgery External oblique intercostal block, Oblique subcostal TAP block, Posterior Rectus sheath block - Bariatric Surgery Candidate, Pain, Postoperative | Not applicable | Completed | Al Mashfa Medical Center | 73 | 2022-10-26 | 2023-02-28 |
| Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery Melatonin 10 MG, Lactose pill - Pain, Postoperative, Narcotic Use | Phase 2 | Completed | Montefiore Medical Center | 60 | 2021-11-16 | 2026-01-30 |
| Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery Opioid-sparing multimodal pain management, Usual care - Postoperative Pain, Narcotic Use | Not applicable | Completed | Ohio State University | 54 | 2021-04-19 | 2023-05-12 |
| Use of Pedometer Following Radical Cystectomy Use of a pedometer following surgery, Standard of care - Bladder Cancer, Ileus | Not applicable | Unknown | Benaroya Research Institute | 35 | 2021-03-01 | 2021-02-16 |
| Sprix for Postoperative Pain Control Following Gynecologic Surgery Sprix - Post Operative Pain Control, Narcotic Use | Phase 4 | Withdrawn | University of Louisville | 2021-01-01 | 2022-07-29 | |
| Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet, Naproxen 500 Mg, Opioids - Opioid Use, Opioid Dependence | Phase 2 | Active not recruiting | Northwestern University | 60 | 2021-01-01 | 2024-11-27 |
| An Analysis of the Efficacy of a Pre-Emptive Multimodal Pain Regimen in Reducing Acute Post-Operative Pain and Narcotic Pain Medication Requirements in Spine Surgery Pre-op Multimodal analgesia (MMA) regimen + standard post-op oxycodone - Pain, Postoperative, Spine Injuries and Disorders | Phase 4 | Completed | NYU Langone Health | 44 | 2020-08-20 | 2022-07-11 |
| Bupivacaine for Post-operative Pain in Mohs Bupivacaine, Placebo Saline - Pain, Postoperative, Narcotic Use | Phase 4 | Completed | University of Missouri-Columbia | 174 | 2020-07-30 | 2026-10-14 |
| Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy regional nerve block with local anesthesia of bupivacaine with steroid, Placebo regional nerveblock with normal saline - Breast Cancer, Mastectomy | Early Phase 1 | Completed | University of Alabama at Birmingham | 21 | 2020-07-06 | 2022-08-03 |
| Postoperative Opt-In Narcotic Treatment Study POINT - Postoperative Pain, Narcotic Use | Not applicable | Completed | University of California, Los Angeles | 102 | 2020-06-26 | 2021-03-04 |
| A Mobile Application for Post-op Analgesic Consumption Mobile app - Tooth Extraction Status Nos, Post Operative Pain | Not applicable | Withdrawn | Boston University | 2019-10-01 | 2019-10-08 | |
| Intraperitoneal Infusion of Analgesic for Postoperative Pain Management Ropivacaine Infusion from ON-Q Pump, Ropivacaine + Ketorolac Infusion from ON-Q Pump, Normal Saline Infusion from ON-Q Pump - Hysterectomy, Gynecologic Surgical Procedures | Phase 4 | Recruiting | Ying Liu | 120 | 2019-09-30 | 2026-04-09 |
| Diagnosis of Sleep-Related Respiratory Disorders in Patients With Narcotic Medications WatchPAT 200 - Narcotic Use, Central Sleep Apnea | Not applicable | Completed | Kaiser Permanente | 24 | 2019-08-08 | 2026-07-20 |
| Serratus Plane Plus Pectoral I Block Versus Serratus Plane Block for Perioperative Analgesia in Breast Cancer Surgery Serratus Plane Block, Serratus Plane Block plus Pectoral I Block - Postoperative Pain, Postoperative Nausea | Not applicable | Completed | Bezmialem Vakif University | 60 | 2019-04-06 | 2020-02-25 |
| Pain Control Following Sinus Surgery OxyCODONE 5 Mg (milligram) Oral Tablet, Ibuprofen 600 Mg (milligram) Oral Tablet, Acetaminophen 650 MG (milligram) Oral Tablet - Sinusitis, Opioid Use | Phase 4 | Completed | Stanford University | 118 | 2019-04-04 | 2021-09-01 |
| Nonopioid Analgesia After Arthroscopic Meniscus Surgery Celecoxib, Hydrocodon/Acetaminophen, Ketorolac - Meniscus Disorder, Narcotic Use | Early Phase 1 | Completed | Henry Ford Health System | 61 | 2019-01-22 | 2023-12-05 |
| Nonopioid Analgesia After Labral Surgery Celecoxib, Hydrocodone-Acetaminophen, Ketorolac - Narcotic Use | Phase 2 / Phase 3 | Recruiting | Henry Ford Health System | 100 | 2019-01-22 | 2019-01-31 |
Showing 20 of 27. Sign in to see all of them.
Pain, Postoperative (15) · Opioid-Related Disorders (5) · Agnosia (4) · Pain (4) · Back Pain (2) · Chronic Pain (2) · Patient Satisfaction (2) · Acute Pain (1) · Back Injuries (1) · Breast Neoplasms (1) · Constipation (1) · Disease (1) · Head and Neck Neoplasms (1) · Ileus (1) · Medication Adherence (1)
Pathological Conditions, Signs and Symptoms (18) · Signs and Symptoms (18) · Neurologic Manifestations (17) · Pathologic Processes (15) · Postoperative Complications (15) · Pain (13) · Chemically-Induced Disorders (5) · Mental Disorders (5) · Nervous System Diseases (5) · Substance-Related Disorders (5) · Narcotic-Related Disorders (4) · Neurobehavioral Manifestations (4) · Perceptual Disorders (4) · Neoplasms by Site (3) · Behavior (2)
Acetaminophen (4) · Gabapentin (4) · oxycodone-acetaminophen (4) · Celecoxib (3) · Ketorolac (3) · Ketorolac Tromethamine (3) · Oxycodone (3) · Bupivacaine (2) · Diazepam (2) · Ibuprofen (2) · Saline Solution (2) · Analgesics, Opioid (1) · Clinical Protocols (1) · Codeine (1) · Cryotherapy (1)
Henry Ford Health System (2) · Al Mashfa Medical Center (1) · Benaroya Research Institute (1) · Bezmialem Vakif University (1) · Boston University (1) · Brest, Norman A., M.D. (1) · Foundation for Orthopaedic Research and Education (1) · Hartford Hospital (1) · Indiana University (1) · Kaiser Permanente (1) · Khon Kaen University (1) · Mayo Clinic (1) · Montefiore Medical Center (1) · NYU Langone Health (1) · Northwestern University (1)
United States (23) · Canada (1) · Saudi Arabia (1) · Thailand (1) · Turkey (Türkiye) (1)
Toufic R Jildeh, MD (2) · Apkar V Apkarian, PhD (1) · Arnaud Bewley, MD (1) · Dennis Hwang, MD (1) · Frank Darras, MD (1) · Gregory M Mundis, MD (1) · Insiyyah Y Patanwala (1) · James Wu, MD (1) · Jason Baker, DMD (1) · Jennifer Keller, MD (1) · John Corman, MD (1) · John M Capelle, MD (1) · John Small, MD (1) · Krista Reagan, MD (1) · Michael W Yeh, MD (1)
PMID 27869630, PMID 30793426, PMID 31185928, PMID 32622918, PMID 33329766, PMID 33590418, PMID 34351376, PMID 34495283, PMID 35221650