52 completed, 27 recruiting, 25 unknown, 15 not yet recruiting. 67 Not applicable, 25 Phase 2, 15 Phase 4, 11 Phase 3, 4 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Manualized Assessment and Treatment Model of Challenging Behavior Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking - Problem Behavior, Aggression | Not applicable | Recruiting | Rutgers, The State University of New Jersey | 30 | 2026-12-31 | 2026-05-08 |
| Biology Guided Therapy Recommendations for Treatment Determination of Hormone Receptor-Positive Advanced, Unresectable or Metastatic Breast Cancer, ENDORSE Trial Biopsy Procedure, Biospecimen Collection, Bone Scan - Advanced Hormone Receptor-Positive Breast Carcinoma, Anatomic Stage III Breast Cancer AJCC v8 | Phase 1 | Not yet recruiting | City of Hope Medical Center | 20 | 2026-12-19 | 2026-05-15 |
| Titanium Particle Release Across Non-Surgical Peri-implantitis Therapies Mechanical Debridement with Titanium Curettes, Mechanical Debridement with Plastic Curettes, 940 nm Diode Laser Decontamination - Peri-implantitis | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi | 70 | 2026-10-15 | 2026-09-10 |
| A 6-Month MDR-END Plus Regimen for Rifampicin-Resistant Tuberculosis MDR-END Plus regimen, Standard-of-care (SoC) treatment - Rifampicin-Resistant Tuberculosis | Phase 3 | Not yet recruiting | Seoul National University Hospital | 294 | 2026-10-01 | 2026-06-30 |
| Eco-guided Neuromodulation of the Femoral Nerve on the Performance of Amateur Athletes. Theta Burst Protocol, 10-10-10 Protocol, 5-55 Protocol - Healthy Volunteers, Neuromuscular Function | Not applicable | Recruiting | Universitat Internacional de Catalunya | 23 | 2026-09-01 | 2026-07-22 |
| Optimizing H. Pylori Eradication Regimen Under Intensified Acid Suppression Keverprazan Hydrochloride 20 mg TID, Minocycline 100 mg (10-Day Regimen), Keverprazan Hydrochloride 20 mg BID - HELICOBACTER PYLORI INFECTIONS | Phase 4 | Not yet recruiting | Qilu Hospital of Shandong University | 316 | 2026-08-01 | 2026-08-06 |
| Preoperative Ivabradine Doses for Hemodynamic Stability in FESS Ivabradine 5 mg/5 mg regimen, Ivabradine 5 mg/7.5 mg regimen, Placebo - Hemodynamic Instability | Not applicable | Not yet recruiting | Minia University | 60 | 2026-08-01 | 2026-09-01 |
| Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol - Otitis Media, Otitis Media Effusion | Not applicable | Not yet recruiting | Sarah Vidal | 200 | 2026-08-01 | 2026-06-10 |
| Key Diagnostic & Therapeutic Technologies for Severe Acute High Altitude Disease (SAHAD): Integration and Application Multicenter study of HAPE：CPAP or BiPAP Group, Multicenter study of HAPE group：NO Group, Protocol for Proteomics and Peptidomics Study of HAPE：Case Group - Severe High Altitude Pulmonary Edema, Severe High Altitude Cerebral Edema | Not applicable | Not yet recruiting | Tibet Autonomous Region People's Hospital | 3035 | 2026-07-01 | 2026-06-10 |
| Investigation of Pain Modulation Phenotypes in Female Patients With Fibromyalgia Quantitative Sensory Tests(QST) protocol, Clinical Scales - Fibromyalgia (FM), Quantitative Sensory Testing | Not yet recruiting | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 82 | 2026-07-01 | 2026-07-07 | |
| Effects of Conditioning Activities in Female Athletes post-activation performance enhancement (PAPE) protocol - Placebo Effect, Physical Performance | Not applicable | Not yet recruiting | Universidade Federal do Triangulo Mineiro | 20 | 2026-05-10 | 2026-04-23 |
| The ACURE Trial: Acupuncture for Colorectal Recovery Electroacupuncture (EA), Sham Electroacupuncture (SA), Enhanced Recovery After Surgery (ERAS) Protocol - Colorectal Neoplasms, Ileus Postoperative | Not applicable | Not yet recruiting | Chang Gung Memorial Hospital | 240 | 2026-04-01 | 2026-04-06 |
| Reducing Chronic Pain After Lung Surgery: A Trial of Limiting NSAIDs During Recovery no NSAID, protocol for administering NSAIDs already used in routine care - Chronic Post-operative Pain | Phase 3 | Not yet recruiting | University Hospital, Strasbourg, France | 270 | 2026-04-01 | 2025-08-07 |
| The Efficacy and Safety of Pola-ZR-Glo in Older Treatment-naive Patients With LBCL Pola-ZR-Glo (Polatuzumab Vedotin, Zanubrutinib, Lenalidomide and Glofitamab) regimen - Large B-Cell Lymphoma (LBCL) | Phase 2 | Recruiting | Ruijin Hospital | 30 | 2026-03-31 | 2026-05-08 |
| Developing a First-void Urine-based Infection Model to Study HPV-specific Antibody-virion Interaction Before and After HPV Vaccination Gardasil 9 (2 dose regimen) - Human Papilloma Virus Infection Type 16 | Phase 2 | Recruiting | Universiteit Antwerpen | 50 | 2026-03-25 | 2026-03-27 |
| Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ Adapted Surviving Sepsis Campaign (SSC) Protocol, Standard Clinical Care - Sepsis, Septic Shock | Not applicable | Completed | Al-Azhar University | 120 | 2026-03-03 | 2026-10-16 |
| MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity MOTS-c (MDP), Placebo, Route Subcutaneous injection - Prediabetes, Insulin Resistance | Phase 2 | Recruiting | Hudson Biotech | 120 | 2026-02-02 | 2026-04-01 |
| The Correlation and Mechanistic Study of GGCX Gene With Prognosis in Acute Ischemic Stroke Usually, all enrolled patients with acute ischemic stroke will receive routine medication and/or surgical treatment according to clinical diagnosis and treatment protocols. - Acute Ischemic Stroke | Not yet recruiting | Peking University Aerospace Center Hospital | 1500 | 2026-01-25 | 2025-12-08 | |
| End-of-life Care in Mechanically Ventilated Patients: Impact of a Comprehensive Palliative Care Protocol in the Intensive Care Setting Protocol for palliative care and life-support withdrawal - Palliative Care, Withdrawal of Life Support | Not applicable | Not yet recruiting | Nantes University Hospital | 720 | 2026-01-10 | 2026-01-26 |
| Office Hysteroscopy in Postmenopausal Women: A Randomized Trial of Cervical Preparation Strategies No Cervical Preparation, Misoprostol ( Cytotec) 200 microgram a tablet, Vaginal Estrogen (7-Day Regimen) - Postmenopausal Women, Intrauterine Diseases | Not applicable | Recruiting | Faculty of Medicine of Tunis | 120 | 2026-01-02 | 2026-10-16 |
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Pain, Postoperative (5) · Stroke (5) · Leukemia, Myeloid, Acute (4) · Breast Neoplasms (3) · Intermittent Fasting (3) · Tuberculosis, Multidrug-Resistant (3) · Agnosia (2) · Anxiety Disorders (2) · Colorectal Neoplasms (2) · Depression (2) · Fibrosis (2) · Heart Arrest (2) · Immunoglobulin Light-chain Amyloidosis (2) · Obesity (2) · Papillomavirus Infections (2)
Alexion Pharmaceuticals, Inc. (2) · Boston Medical Center (2) · Emory University (2) · Hospital de Clinicas de Porto Alegre (2) · Huashan Hospital (2) · Kanuni Sultan Suleyman Training and Research Hospital (2) · Karolinska Institutet (2) · Medical University of Vienna (2) · NYU Langone Health (2) · The First Affiliated Hospital with Nanjing Medical University (2) · The University of Texas Health Science Center, Houston (2) · University of Washington (2) · Afyonkarahisar Health Sciences University (1) · Al-Azhar University (1) · American Regent, Inc. (1)
United States (35) · China (22) · Turkey (Türkiye) (9) · Brazil (8) · Spain (7) · United Kingdom (7) · Italy (6) · France (5) · Netherlands (5) · Germany (4) · South Korea (4) · Sweden (4) · Australia (3) · Austria (3) · Belgium (3)
Giovannino Ciccone, MD (2) · Scott Swenson, MD (2) · Alexandre J Zampieri, Graduate (1) · Anastasia Trikoupi (1) · Andreia C O Silva, MSc (1) · April Maa, MD (1) · Arabella Fischer, Dr. (1) · Arvin Garg, MD, MPH (1) · Ashok Jain, MD (1)
PMID 42212672, PMID 12115716, PMID 16703526, PMID 21235799, PMID 21486866, PMID 22102090, PMID 22122001, PMID 23254550, PMID 23667204, PMID 23840211, PMID 23965945, PMID 24187115, PMID 24419308, PMID 24626074, PMID 25165974, PMID 25560448, PMID 25654175, PMID 26282654, PMID 27206047, PMID 27565186, PMID 27783688, PMID 29274643, PMID 29289383, PMID 29364196, PMID 31011303, PMID 31592079, PMID 31736781, PMID 31892668, PMID 31964380, PMID 32016528, PMID 32282706, PMID 32617767, PMID 32820135, PMID 33538338, PMID 33663942, PMID 33689063, PMID 33902087, PMID 33993135, PMID 34057734, PMID 34083345, PMID 34753208, PMID 34789277, PMID 35289396, PMID 35377708, PMID 35428342, PMID 35622826, PMID 35790108, PMID 36945475, PMID 37072637, PMID 37158965
2004 (1), 2025 (1), KL2TR003168 (1), P30CA022453 (1), P30CA033572 (1), R00HD056160 (1), R01HL102387 (1), R01HL112815 (1), R01HL147811 (1), R01NR009093 (1), U01HL159882 (1)