144 completed, 49 unknown, 31 terminated, 19 recruiting. 275 Phase 2, 49 Phase 3, 43 Phase 1.
Follow Myocardial Infarction: new trials by email Literature Review of Myocardial Infarction trials Research Report on Myocardial Infarction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating SGLT2 Inhibitors for the Reduction of No-Reflow Phenomenon in Patients Undergoing PCI Empagliflozin (SGLT2i), dapagliflozin, Standard medical treatment - No Reflow Phenomenon, Reperfusion Injuries, Myocardial | Phase 2 | Not yet recruiting | Al-Azhar University | 100 | 2027-01-01 | 2026-10-27 |
| CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock Methylprednisone, Standard of Care (SOC) - Cardiogenic Shock, Heart Failure | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 30 | 2026-10-01 | 2026-08-13 |
| A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease VERVE-102, Placebo - Atherosclerosis, Cardiovascular Disease | Phase 2 | Not yet recruiting | Verve Therapeutics, Inc. | 175 | 2026-10-01 | 2026-09-24 |
| Randomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic Shock istaroxime, placebo - Cardiogenic Shock | Phase 2 / Phase 3 | Recruiting | Seismic Pharmaceuticals Operations LLC | 600 | 2026-09-09 | 2026-09-23 |
| Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients empagliflozin, Placebo - ST-elevation Myocardial Infarction (STEMI), Acute Myocardial Infarction (AMI) | Phase 2 | Not yet recruiting | Rehman Medical Institute - RMI | 480 | 2026-09-01 | 2026-08-06 |
| Combined Antioxidant Therapy for Acute Myocardial Infarction Combined antioxidant therapy, Placebo - Acute Myocardial Infarction (AMI), ST Elevation (STEMI) Myocardial Infarction | Phase 2 | Not yet recruiting | University of Chile | 46 | 2026-09-01 | 2026-08-20 |
| Comparative Evaluation of Sustained meChanical AsPiration Thrombectomy and no Thrombus Modification for Pre-stent Thrombus bUrden Reduction in Patients With Acute Myocardial Infarction Study: the CAPTURE AMI Study Sustained thrombectomy, Percutaneous Coronary Intervention - STEMI - ST Elevation Myocardial Infarction | Phase 2 / Phase 3 | Recruiting | Oxford University Hospitals NHS Trust | 60 | 2026-07-08 | 2026-07-10 |
| Prevention of Reperfusion Injury Outcomes Through Effective Cardioprotection Targeting Myocardial Infarction Xolatryp, Placebo - Myocardial Infarction, Reperfusion Injury | Phase 2 | Recruiting | Nyrada Pty Ltd | 300 | 2026-07-02 | 2026-10-06 |
| Effect of Guanxinning Tablet on Coronary Microcirculation After Primary Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction Guanxinning Tablet(GXNT), Placebo - STEMI (ST Elevation MI), STEMI - ST Elevation Myocardial Infarction | Phase 2 | Not yet recruiting | Beijing Anzhen Hospital | 70 | 2026-06-01 | 2026-06-02 |
| Recombinant Human Thymosin Beta 4 for Injection(NL005) for Acute Myocardial Infarction Recombinant Human Thymosin Beta 4 Injection (NL005), Placebo - Acute Myocardial Infarction (AMI), Acute Myocardial Infarction of Anterior Wall | Phase 2 | Not yet recruiting | Beijing Northland Biotech. Co., Ltd. | 189 | 2026-05-18 | 2026-05-14 |
| Safety and Efficacy of MiSaver (CB Cells) for Acute Myocardial Infarction, Phase II Cord Blood Nucleated cells - Acute Myocardial Infarction (AMI) | Phase 2 | Not yet recruiting | HONYA Medical Co Ltd | 102 | 2026-03-30 | 2026-03-11 |
| A Research Study to Evaluate the Efficacy and Safety of SGC001 in Patients With Anterior Wall ST-Segment Elevation Myocardial Infarction SGC001 injection, Placebo - Acute Anterior ST-Segment Elevation Myocardial Infarction | Phase 2 | Recruiting | Beijing Sungen Biomedical Technology Co., Ltd | 210 | 2026-03-09 | 2026-07-13 |
| Inhibition of Late Sodium Current (INa) to Prevent Coronary MICROvascular Dysfunction in Patients Presenting With ST-Elevation Myocardial Infarction and Multivessel Disease: INaMICRON Study Ranolazine - STEMI (ST Elevation MI) | Phase 2 / Phase 3 | Recruiting | Federico II University | 100 | 2026-02-01 | 2026-03-11 |
| Ultralow Dose PET Imaging of 18F-flurpiridaz 18F-flurpiridaz - Healthy Volunteer, Coronary Arterial Disease | Phase 2 | Enrolling by invitation | Akiva Mintz | 200 | 2025-12-16 | 2026-04-13 |
| Effect of Colchicine in Patients With Myocardial Infarction Colchicine, Placebo oral tablet - Myocardium; Injury, Myocardial Infarction | Phase 2 | Withdrawn | Shifa Tameer-e-Millat University | 2025-12-01 | 2023-04-12 | |
| Randomised EValuation of Therapies for microvAscuLar Injury in STEACS Therapeutic sequence, Diagnostic sequence - STEMI (ST Elevation MI) | Phase 2 | Not yet recruiting | CorFlow Therapeutics AG | 250 | 2025-09-01 | 2025-04-20 |
| Dexrazoxane to Protect Against Hemorrhagic STEMI Dexrazoxane, Normal Saline - Acute Myocardial Infarction (AMI) | Phase 2 | Completed | Rohan Dharmakumar | 50 | 2025-08-30 | 2026-05-26 |
| Focused Orticumab Research for Treating Inflammation in Coronary Arteries Orticumab, Placebo - Acute Coronary Syndromes, Coronary Arterial Disease (CAD) | Phase 2 | Recruiting | Abcentra | 240 | 2025-08-11 | 2026-01-27 |
| A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care. AK1967 (Invobenitug also known as Procizumab), Placebo - Shock, Cardiogenic | Phase 1 / Phase 2 | Recruiting | 4TEEN4 Pharmaceuticals GmbH | 90 | 2025-07-13 | 2026-09-14 |
| Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI L-Carnitine, The standard care for the management of myocardial infarction post PCI - Reperfusion Injury, Myocardial, Myocardial Infarction | Phase 2 | Active not recruiting | Ain Shams University | 76 | 2025-06-01 | 2026-09-01 |
Showing 20 of 275. Sign in to see all of them.
ST Elevation Myocardial Infarction (85) · Coronary Artery Disease (30) · Heart Failure (28) · Myocardial Ischemia (24) · Acute Coronary Syndrome (23) · Shock, Cardiogenic (18) · Cardiovascular Diseases (17) · Heart Diseases (16) · Non-ST Elevated Myocardial Infarction (16) · Inflammation (13) · Angina, Unstable (12) · Angina Pectoris (10) · Coronary Disease (10) · Myocardial Reperfusion Injury (10)
Pathological Conditions, Signs and Symptoms (275) · Ischemia (274) · Necrosis (274) · Pathologic Processes (273) · Vascular Diseases (271) · Infarction (270) · Heart Diseases (259) · Cardiovascular Diseases (258) · Myocardial Ischemia (251) · Arterial Occlusive Diseases (33) · Arteriosclerosis (33) · Signs and Symptoms (33) · Coronary Disease (28) · Neurologic Manifestations (27)
Sodium Chloride (11) · Clopidogrel (9) · Aspirin (8) · Atorvastatin (8) · Percutaneous Coronary Intervention (7) · Saline Solution (7) · Ticagrelor (7) · Standard of Care (5) · Colchicine (3) · Doxycycline (3) · Heparin (3) · Istaroxime (3) · Warfarin (3) · dapagliflozin (3) · empagliflozin (3)
University of Alberta (5) · Amaranth Medical Inc. (4) · Hospices Civils de Lyon (4) · University Medical Center Groningen (4) · AstraZeneca (3) · Brigham and Women's Hospital (3) · Mallinckrodt (3) · Oslo University Hospital (3) · Papworth Hospital NHS Foundation Trust (3) · Stanford University (3) · University Health Network, Toronto (3) · Bayer (2) · Bioheart, Inc. (2) · Catholic University of the Sacred Heart (2) · Copenhagen University Hospital, Rigshospitalet (2)
United States (72) · Canada (33) · Poland (27) · Germany (26) · Netherlands (25) · United Kingdom (24) · China (17) · Italy (17) · Belgium (16) · Denmark (15) · Hungary (15) · France (14) · Spain (14) · South Korea (13) · Czechia (12)
Antonio Colombo, MD (3) · Ali Eskandari, MD (2) · Andreas M Zeiher, MD (2) · Antonio Abbate, MD, PhD (2) · Christopher Chen, BMBCh, MRCP, FAMS, FRCPE (2) · Filippo Crea, MD (2) · Hossein Vakili, M.D. (2) · Hyo-Soo Kim, MD (2) · Joshua M Hare, MD (2) · Jun Li, MD (2) · Maryam Keshtkar-Jahromi, M.D.; M.P.H. (2) · Muhammad Munawar, SpJP(K), MD (2) · Seyed Mostafa Razavi, MD (2) · Sharareh Gholamin, MD (2)
PMID 17090774, PMID 19118718, PMID 21079055, PMID 21709062, PMID 22212857, PMID 22795280, PMID 29386200, PMID 9462531, PMID 10811917, PMID 12460865, PMID 15016484, PMID 15480537, PMID 15498829, PMID 16413875, PMID 16750696, PMID 16990383, PMID 16990385, PMID 17138963, PMID 17172279, PMID 17320744, PMID 17698683, PMID 18032779, PMID 18460663, PMID 18535785, PMID 18559698, PMID 18599344, PMID 18984888, PMID 19064521, PMID 19116389, PMID 19131132, PMID 19232907, PMID 19237716, PMID 19451353, PMID 19491213, PMID 19491386, PMID 19608137, PMID 19608488, PMID 19640572, PMID 19679246, PMID 19858734, PMID 19923168, PMID 19940774, PMID 19958860, PMID 19958867, PMID 20012748, PMID 20102300, PMID 20124733, PMID 20189026, PMID 20194878, PMID 20298926
2016 (3), 2018 (2), 2014 (1), 2015 (1), 2017 (1), 2023 (1), 2025 (1), R01HL046959 (1), R01HL103927 (1), R44HL091699 (1), R44HL117572 (1), RC3HL103356-01 (1)