48 completed, 16 unknown, 8 terminated, 5 withdrawn. 85 Phase 1, 43 Phase 2.
Follow Myocardial Infarction: new trials by email Literature Review of Myocardial Infarction trials Research Report on Myocardial Infarction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of STX-1150 in Participants With Elevated Low-Density Lipoprotein Cholesterol (LDL-C) STX-1150 - Elevated LDL-C and High Cholesterol | Phase 1 | Recruiting | Monash University | 64 | 2026-06-30 | 2026-09-21 |
| Safety and Efficacy of FAP iCDC in Acute Myocardial Infarction With Cardiogenic Shock FAP allogeneic immunosuppressive CAR-DC - Cardiogenic Shock, Cardiogenic Shock Post Myocardial Infarction | Phase 1 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 18 | 2026-01-20 | 2026-02-02 |
| Safety and Efficacy of Epicardial Implantation of Collagen Membranes With Allogeneic Adipose Derived Stem Cells VB-C01 cellularised patch - CABG-patients, Heart Failure | Phase 1 | Not yet recruiting | Viscofan | 10 | 2025-09-01 | 2025-05-04 |
| A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care. AK1967 (Invobenitug also known as Procizumab), Placebo - Shock, Cardiogenic | Phase 1 / Phase 2 | Recruiting | 4TEEN4 Pharmaceuticals GmbH | 90 | 2025-07-13 | 2026-09-14 |
| The Transendocardial Autologous Cells (hMSC) or (hMSC) and (hCSC) in Ischemic Heart Failure Trial. Autologous hMSCs, Autologous Human C-Kit CSCs II, Placebo - Chronic Ischemic Left Ventricular Dysfunction, Myocardial Infarction | Phase 1 / Phase 2 | Withdrawn | Joshua M Hare | 2025-03-01 | 2020-10-22 | |
| Pilot Study of IC14 (Atibuclimab), an Anti-CD14 Monoclonal Antibody, to Treat STEMI Atibuclimab (IC14), 20 mg/kg intravenously, once, Placebo, 150 mL intravenously, once - STEMI, STEMI (ST Elevation MI) | Phase 1 / Phase 2 | Active not recruiting | Implicit Bioscience | 10 | 2025-02-06 | 2026-03-27 |
| A Research Study to Evaluate the Safety and Preliminary Efficacy of SGC001 in Patients With Myocardial Infarction SGC001, Placebo - Anterior Myocardial Infarction | Phase 1 | Completed | Beijing Sungen Biomedical Technology Co., Ltd | 38 | 2025-01-20 | 2026-01-12 |
| A Research Study to Evaluate the Safety and Tolerability of SGC001 in Healthy Subjects SGC001, Placebo - Anterior Myocardial Infarction | Phase 1 | Completed | Beijing Sungen Biomedical Technology Co., Ltd | 49 | 2024-08-20 | 2025-11-25 |
| A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage C Istaroxime, Placebo - Cardiogenic Shock | Phase 1 / Phase 2 | Active not recruiting | Windtree Therapeutics | 20 | 2024-06-01 | 2025-08-20 |
| Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO Packed Red Blood Cells (PRBCs) - Cardiogenic Shock, Extracorporeal Membrane Oxygenation | Phase 1 | Recruiting | University Hospital, Lille | 236 | 2023-09-18 | 2026-09-17 |
| Study to Compare the Pharmacokinetics and Pharmacodynamics of ASA Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Adult Subjects With Obstructive or Restrictive Pulmonary Function single dose (100 mg) of ASA, single dose (162 mg) of non-enteric-coated chewable aspirin tablets - Obstructive Pulmonary Function, Restrictive Pulmonary Function | Phase 1 | Terminated | Vectura, Inc. | 4 | 2023-03-11 | 2024-03-22 |
| Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults. ASA, non-enteric-coated chewable aspirin - Healthy Volunteers | Phase 1 | Completed | Vectura, Inc. | 86 | 2022-10-14 | 2024-03-22 |
| A Study of NP-011 in Healthy Volunteers NP-011 (Single Ascending Dose Phase), NP-011 (Multiple Ascending Dose Phase), NP-011 (Placebo) - Myocardial Infarction | Phase 1 | Completed | Nexel Co., Ltd. | 64 | 2022-06-10 | 2023-08-03 |
| Co-transplantation of Mesenchymal Stem Cell Derived Exosomes and Autologous Mitochondria for Patients Candidate for CABG Surgery mitochondria and MSC-derived exosomes - Myocardial Infarction, Myocardial Ischemia | Phase 1 / Phase 2 | Unknown | Tehran University of Medical Sciences | 20 | 2022-04-20 | 2022-12-30 |
| The Protective Effect of Prostaglandin on Coronary Microcirculation and Ventricular Remodeling After Reperfusion Therapy in Acute ST-segment Elevation Myocardial Infarction beprostaglandin sodium - STEMI | Phase 1 / Phase 2 | Unknown | Shenzhen People's Hospital | 220 | 2022-01-01 | 2021-09-14 |
| AMI-DC in Patients With Anterior Wall Myocardial Infarction Autologous peripheral blood-derived tolerogenic dendritic cells - Myocardial Infarction | Phase 1 / Phase 2 | Unknown | The Catholic University of Korea | 30 | 2021-06-07 | 2022-09-26 |
| Intravenous MSC Therapy on Ischemia-Reperfusion Injury in Patients With Myocardial Infarction WJ-MSC cells implantation, CTSTMD PBS without WJ-MSC, Conventional drug therapy - Myocardial Infarction | Phase 1 / Phase 2 | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 90 | 2021-03-01 | 2021-02-21 |
| MiSaver® Stem Cell Treatment for Heart Attack (Acute Myocardial Infarction) MiSaver® - Myocardial Infarction | Phase 1 / Phase 2 | Completed | Honya Medical Inc | 11 | 2021-01-26 | 2024-03-29 |
| Role of Alprazolam in the Management of Acute Coronary Syndrome Alprazolam, Placebo - Acute Coronary Syndrome, Myocardial Infarction | Phase 1 / Phase 2 | Unknown | Sohaib Ashraf | 48 | 2020-12-25 | 2021-01-20 |
| SP16 Inflammatory Response Inhibition Trial SP16 - Myocardial Infarction, Inflammation | Phase 1 / Phase 2 | Completed | Serpin Pharma, LLC | 10 | 2020-02-24 | 2023-01-30 |
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ST Elevation Myocardial Infarction (13) · Coronary Artery Disease (12) · Heart Failure (12) · Cardiovascular Diseases (7) · Heart Diseases (7) · Acute Coronary Syndrome (6) · Myocardial Ischemia (6) · Inflammation (5) · Infarction (4) · Shock, Cardiogenic (4) · Stroke (4) · Coronary Disease (3) · Respiratory Aspiration (3) · Thrombosis (3)
Ischemia (85) · Necrosis (85) · Pathologic Processes (85) · Pathological Conditions, Signs and Symptoms (85) · Vascular Diseases (84) · Infarction (81) · Myocardial Ischemia (79) · Cardiovascular Diseases (78) · Heart Diseases (78) · Arterial Occlusive Diseases (14) · Arteriosclerosis (14) · Coronary Disease (10) · Brain Diseases (5) · Central Nervous System Diseases (5)
Fish Oils (2) · Omacor (2) · Saline Solution (2) · 3-(2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol (1) · Alprazolam (1) · Aspirin (1) · Atorvastatin (1) · Celecoxib (1) · Congresses as Topic (1) · Corn Oil (1) · Docosahexaenoic Acids (1) · EVP 1001-1 (1) · Everolimus (1) · Gadolinium DTPA (1) · Genes, Mitochondrial (1)
Cedars-Sinai Medical Center (3) · Beijing Sungen Biomedical Technology Co., Ltd (2) · Bioheart, Inc. (2) · Emory University (2) · Mayo Clinic (2) · Stanford University (2) · University of Rochester (2) · Vectura, Inc. (2) · 4TEEN4 Pharmaceuticals GmbH (1) · Abbott Medical Devices (1) · Academy Military Medical Science, China (1) · AdvanceCor GmbH (1) · Angioblast Systems (1) · BioCardia, Inc. (1) · Capricor Inc. (1)
United States (39) · China (6) · Germany (6) · Netherlands (6) · Spain (4) · Canada (3) · Denmark (3) · France (3) · Poland (3) · Argentina (2) · Australia (2) · Israel (2) · Switzerland (2) · United Kingdom (2) · Armenia (1)
Antonio Abbate, MD, PhD (2) · Eduardo Marban, MD, PhD (2) · Warren Sherman, MD (2) · Adelino Leite-Moreira, PhD (1) · Alexandre Mebazaa, Professor (1) · Andreas M Zeiher, MD (1) · Andreas Wielgosz, MD, FRCP(C) (1) · Andrew Pipe, MD (1) · Chris Blanchard, PhD (1) · Christina Vassileva, M.D. (1) · David A. Morrow, MD, MPH (1) · David Holmes, MD (1)
PMID 15246726, PMID 19679246, PMID 19958962, PMID 20236457, PMID 21325598, PMID 21330601, PMID 21422390, PMID 21454794, PMID 21492763, PMID 21502572, PMID 21658561, PMID 21717276, PMID 22052917, PMID 22088800, PMID 22336189, PMID 22951358, PMID 22965994, PMID 22971949, PMID 23594433, PMID 23633132, PMID 23778184, PMID 23979567, PMID 24036024, PMID 24300013, PMID 24691607, PMID 24815497, PMID 25484310, PMID 25805204, PMID 25872588, PMID 26443879, PMID 26836806, PMID 27322478, PMID 28131429, PMID 30181084, PMID 30444173, PMID 30602360, PMID 30860564, PMID 31723612, PMID 32749459, PMID 33475735, PMID 33783498, PMID 34233913, PMID 35092722, PMID 35750637, PMID 35881895, PMID 36049557, PMID 38172601, PMID 39921502, PMID 42165327, PMID 42797369
2014 (1), 2018 (1), R01HL103927 (1), RC3HL103356-01 (1), U54HL081028 (1)