3 completed, 1 recruiting, 1 terminated, 1 unknown. 6 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 3, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Ketamine: new trials by email Literature Review of Ketamine trials Research Report on Ketamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulized Ketamine for the Treatment of Major Depressive Disorder nebulized ketamine, nebulized midazolam - Severe Depression, Moderate Depression | Phase 3 | Recruiting | Theresa Jacob, PhD, MPH | 40 | 2024-10-16 | 2026-04-24 |
| Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery Acetaminophen, Gabapentin, Lidocaine 1% Injectable Solution, Dexmedetomidine, Ketamine, Dexamethasone, Ondansetron - Anesthesia, General Anesthesia | Phase 3 | Unknown | University of Saskatchewan | 60 | 2021-05-15 | 2023-12-20 |
| Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED Intranasal ketamine - Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease | Phase 3 | Terminated | Abigail Nixon | 5 | 2019-12-19 | 2024-11-18 |
| Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy Acetaminophen, gabapentin, Acetaminophen, Ketamine , Lidocaine , Dexmedetomidine - Anesthesia, General Anesthesia | Phase 3 | Completed | University of Saskatchewan | 50 | 2017-10-15 | 2021-08-10 |
| ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD) electroconvulsive therapy (ECT), Ketamine - Treatment Resistant Depression, Electroconvulsive Therapy | Phase 2 / Phase 3 | Completed | Bo Hu | 403 | 2017-04-07 | 2023-09-28 |
| KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain Ketamine (or placebo : isotonic saline solution) - Ketamine, Chronic Post Thoracotomy Pain | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 80 | 2003-01-01 | 2006-04-13 |
Agnosia (2) · Depression (2) · Anemia, Sickle Cell (1) · Depressive Disorder (1) · Depressive Disorder, Major (1) · Depressive Disorder, Treatment-Resistant (1) · Mental Disorders (1) · Neuralgia (1) · Pain (1) · Pathologic Processes (1) · Postoperative Complications (1) · Respiratory Insufficiency (1) · Sleep Apnea Syndromes (1) · Vaso-Occlusive Crises (1)
Nervous System Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Behavior (2) · Behavioral Symptoms (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Anemia (1) · Anemia, Hemolytic (1) · Anemia, Hemolytic, Congenital (1) · Apnea (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Dyssomnias (1) · Genetic Diseases, Inborn (1)
Ketamine (5) · Acetaminophen (2) · Dexamethasone (2) · Dexmedetomidine (2) · Gabapentin (2) · Lidocaine (2) · Ondansetron (2) · Sevoflurane (2) · Electroconvulsive Therapy (1) · Fentanyl (1) · Magnesium Sulfate (1) · Midazolam (1) · Sufentanil (1)
University of Saskatchewan (2) · Abigail Nixon (1) · Assistance Publique - Hôpitaux de Paris (1) · Bo Hu (1) · Theresa Jacob, PhD, MPH (1)
United States (3) · Canada (2) · France (1)
Amit Anand, MD (1) · Jon Gamble, MD (1) · Theresa Jacob, PhD, MPH (1)
PMID 30572160, PMID 37224232, PMID 40900112
2019 (1)