29 completed. 29 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 29 | Completed 29 |
Follow Hypoxia: new trials by email Literature Review of Hypoxia trials Research Report on Hypoxia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men Acetazolamide, Placebo - Sleep-Disordered Breathing | Phase 4 | Completed | University of Zurich | 303 | 2024-07-15 | 2026-06-05 |
| HighCycle Study: Effect of Acetazolamide on Acute Mountain Sickness in Women Compared to Men Acetazolamide, Placebo - Acute Mountain Sickness | Phase 4 | Completed | University of Zurich | 303 | 2024-07-15 | 2026-01-23 |
| HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men Acetazolamide, Placebo - High Altitude | Phase 4 | Completed | University of Zurich | 303 | 2024-07-15 | 2026-06-05 |
| Efficacy of 20% Human Albumin in Reducing Pleural Effusion After Cardiopulmonary Bypass Adding 100ml of 20% human albumin to cardiopulmonary bypass priming solution - Pleural Effusions Post Coronary Artery Bypass Graft, Hypoxia | Phase 4 | Completed | Pauls Stradins Clinical University Hospital | 70 | 2022-09-01 | 2024-11-08 |
| Sargramostim in Patients With Acute Hypoxic Respiratory Failure Due to COVID-19 (SARPAC) Sargramostim, Control - COVID-19 | Phase 4 | Completed | University Hospital, Ghent | 87 | 2020-03-24 | 2022-11-16 |
| Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome Dexmedetomidine, Normal saline - Brain Tumor, Metabolic Disturbance | Phase 4 | Completed | Georgia Tsaousi | 56 | 2020-03-12 | 2026-03-25 |
| Acute Effects of SGLT2 Inhibition on Renal Oxygenation and Autonomic Function in Type 1 Diabetes Forxiga - Nephropathy, Hypoxia | Phase 4 | Completed | Steno Diabetes Center Copenhagen | 30 | 2020-02-01 | 2021-02-03 |
| AT1R Blockade and Periodic Breathing During Sleep in Hypoxia Hyperoxic Hypercapnic Ventilatory Response Test, Hypoxic Hypercapnic Ventilatory Response Test, Repeated Hypoxic Apneas - Sleep Disordered Breathing, Hypoxia | Phase 4 | Completed | University of British Columbia | 14 | 2018-01-01 | 2020-09-04 |
| Neuroimaging During Pure Oxygen Breathing Oxygen - Hyperoxia, Hypoxia, Brain | Phase 4 | Completed | Case Western Reserve University | 33 | 2017-10-02 | 2019-11-13 |
| Muscle Fatigue and Carbonic Anhydrase Inhibitors Acetazolamide, Methazolamide, Placebo - Hypoxia | Phase 4 | Completed | University of British Columbia | 13 | 2016-11-01 | 2018-09-25 |
| Doxapram as an Additive to Propofol Sedation in Sedation for ERCP Doxapram, Placebo - Sedation, Hypoxia | Phase 4 | Completed | Helsinki University Central Hospital | 50 | 2016-10-01 | 2016-12-05 |
| Optimal Oxygenation in the Intensive Care Unit Oxygen - Systemic Inflammatory Response Syndrome | Phase 4 | Completed | Amsterdam UMC, location VUmc | 400 | 2015-02-01 | 2021-04-19 |
| Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study Ketamine, placebo - Pain, Obesity | Phase 4 | Completed | Northwestern University | 80 | 2013-11-01 | 2019-10-07 |
| Acute Ventilatory Response to Hypoxia During Sedation With Dexmedetomidine Compared to Propofol in Healthy Male Volunteers Hypoxic ventilatory response, Hypercapnic ventilatory response - Hypoxia, Anesthetics | Phase 4 | Completed | Karolinska University Hospital | 11 | 2013-05-01 | 2016-02-26 |
| The Effect of Nasal Cannula During the First 2 Hours Postoperative in Patient Undergoing Thoracotomy oxygen cannular - Lung Surgery, Hypoxia | Phase 4 | Completed | Mahidol University | 34 | 2012-11-01 | 2013-08-19 |
| Effect of Systemic Hypoxia and Hyperoxia on Retinal Oxygen Saturation 100% oxygen breathing, 15% oxygen in N2 breathing, 12% oxygen in N2 breathing - Retinal Oxygenation, Retinal Blood Flow | Phase 4 | Completed | Medical University of Vienna | 30 | 2012-06-01 | 2013-01-30 |
| Early Non-invasive Ventilation Outside the Intensive Care Unit Non-invasive ventilation, Standard care - Early Acute Respiratory Failure | Phase 4 | Completed | Università Vita-Salute San Raffaele | 520 | 2012-04-01 | 2025-08-07 |
| Influence of Cardiopulmonary Bypass, and Sevoflurane or Propofol Anesthesia, on Tissue Oxygen Saturation. NIRS during VOT, General anaesthesia with propofol use, General anaesthesia with sevoflurane use - NIR Spectroscopy | Phase 4 | Completed | Medical University of Gdansk | 64 | 2012-03-01 | 2015-11-02 |
| Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea Indacaterol maleate, Placebo - COPD, Lung Diseases | Phase 4 | Completed | University of Milan | 60 | 2011-05-01 | 2014-10-29 |
| Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy Alfentanil, Normal saline, Targeted controlled infusion - Hypoxemia | Phase 4 | Completed | Chang Gung Memorial Hospital | 173 | 2010-10-01 | 2015-08-13 |
Showing 20 of 29. Sign in to see all of them.
Altitude Sickness (3) · Apnea (3) · Hyperoxia (3) · Sleep Apnea, Obstructive (3) · Acute Lung Injury (2) · Heart Failure (2) · Hypercapnia (2) · Motor Activity (2) · Sleep Apnea Syndromes (2) · Brain Neoplasms (1) · COVID-19 (1) · Critical Illness (1) · Diabetes Mellitus, Type 1 (1) · Diabetic Neuropathies (1)
Pathological Conditions, Signs and Symptoms (29) · Signs and Symptoms (29) · Signs and Symptoms, Respiratory (29) · Respiratory Tract Diseases (12) · Respiration Disorders (11) · Nervous System Diseases (8) · Dyssomnias (5) · Pathologic Processes (5) · Sleep Disorders, Intrinsic (5) · Cardiovascular Diseases (4) · Lung Diseases (4) · Neurologic Manifestations (4) · Sleep Wake Disorders (4) · Heart Diseases (3) · Sleep Apnea Syndromes (3)
Acetazolamide (7) · Oxygen (4) · Carvedilol (2) · Nebivolol (2) · Noninvasive Ventilation (2) · Saline Solution (2) · Standard of Care (2) · Alfentanil (1) · Anesthesia, General (1) · Bisoprolol (1) · Budesonide (1) · Dexmedetomidine (1) · Doxapram (1) · Ketamine (1) · Losartan (1)
University of Zurich (5) · University of British Columbia (2) · Amsterdam UMC, location VUmc (1) · Assistance Publique - Hôpitaux de Paris (1) · Association pour la Recherche en Physiologie de l'Environnement (1) · Case Western Reserve University (1) · Centro Cardiologico Monzino (1) · Chang Gung Memorial Hospital (1) · Georgia Tsaousi (1) · Helsinki University Central Hospital (1) · Istituto Auxologico Italiano (1) · Karolinska University Hospital (1) · Mahidol University (1) · Medical University of Gdansk (1) · Medical University of Vienna (1)
Italy (4) · United States (4) · Kyrgyzstan (3) · Canada (2) · France (2) · Greece (2) · Switzerland (2) · Austria (1) · Belgium (1) · Denmark (1) · Finland (1) · Kazakhstan (1) · Latvia (1) · Netherlands (1) · Peru (1)
Talant Sooronbaev, Prof. Dr. (3) · Konrad E Bloch, MD (2) · Michael Furian, Prof. Dr. (2) · Alexandra Biedrzycka, M.D., Ph.D. (1) · Bart Lambrecht (1) · Chung Hsing Hsieh, M.D. (1) · Eva Strike, MD, PhD (1) · Fabiola Leon-Velarde, PHD (1) · Georgia Tsaousi, Professor (1) · Giancarlo Marenzi, MD (1) · Glen E Foster, Ph.D. (1) · Glen Foster, PhD (1)
PMID 16627862, PMID 18388356, PMID 18595959, PMID 18719057, PMID 20426859, PMID 21450573, PMID 25015353, PMID 27401083, PMID 29406184, PMID 29792554, PMID 30739002, PMID 31993819, PMID 32410951, PMID 32503663, PMID 32559419, PMID 34386735, PMID 34463696, PMID 36459994, PMID 37700687, PMID 39753402
2014 (1), 2019 (1)