2306 completed, 345 unknown, 336 recruiting, 194 terminated. 1469 Not applicable, 518 Phase 2, 420 Phase 1, 316 Phase 3, 191 Phase 4.
Follow Diabetes Mellitus, Type 1: new trials by email Literature Review of Diabetes Mellitus, Type 1 trials Research Report on Diabetes Mellitus, Type 1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Insul-In This Together: Leveraging Family Support and Diabetes Technology for Adolescents Living With Type 1 Diabetes Insul-In This Together - Diabetes Type 1 | Not applicable | Not yet recruiting | Stanford University | 200 | 2028-01-01 | 2026-10-05 |
| GLP-1 RA for Stage 1 Type 1 Diabetes Semaglutide, Placebo - Stage 1 Diabetes Mellitus, Type 1 | Phase 2 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 15 | 2027-09-01 | 2026-02-24 |
| Oral Galactose as a Substrate for Post-Exercise Skeletal Muscle Glycogen Repletion in Individuals With Type 1 Diabetes galactose - Type 1 Diabetes | Not applicable | Not yet recruiting | University of Aarhus | 16 | 2027-02-01 | 2026-08-19 |
| Technology Knowledge Optimization for Type 1 Diabetes in Schools TeKnO T1D curriculum - Type 1 Diabetes (T1D) | Not applicable | Not yet recruiting | University of Pittsburgh | 86 | 2027-02-01 | 2026-03-19 |
| ENCRT-103-hPI: Evaluation of an Immune-protected ENCRT-103-hPI Containing Primary Human Islets in Adults With Type 1 Diabetes, With and Without Standard-of-care Portal Vein Islet Infusion. ENCRT-103-hPI encompasses the ENC-103 device, which will be implanted once loaded with primary islet cargo. - Type 1 Diabetes | Phase 1 | Not yet recruiting | Encellin | 10 | 2027-01-06 | 2026-08-20 |
| SHIELD-T1D: Shingrix and GLP-1 Agonist for Beta-Cell Preservation in Recent-Onset Type 1 Diabetes. Recombinant Zoster Vaccine (Shingrix; RZV), Semaglutide (Ozempic®), Placebo (saline injection) - Type 1 Diabetes Mellitus | Phase 2 | Not yet recruiting | Ministry of Health, Saudi Arabia | 240 | 2027-01-01 | 2026-05-29 |
| Sequential Immune Modulation and Antigen-Specific Tolerance Induction for Disease Modification in Recent-Onset Type 1 Diabetes Teplizumab, Intralymphatic Insulin Immunotherapy (ILIT) - Type 1 Diabetes Mellitus (T1DM), Type 1 Diabetes Mellitus | Phase 1 | Not yet recruiting | Abdullah Kars | 60 | 2027-01-01 | 2026-05-27 |
| Inspiratory Muscle Strength Training in Adults With Type 1 Diabetes High-Resistance Inspiratory Muscle Strength Training, Sham Inspiratory Muscle Strength Training - Type 1 Diabetes | Not applicable | Not yet recruiting | Florida State University | 30 | 2027-01-01 | 2026-10-08 |
| Verapamil In Preclinical Type 1 Diabetes Verapamil 120 Mg/24 Hours Oral Capsule, Extended Release, Placebo, blood sampling - Type 1 Diabetes | Phase 2 / Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2027-01-01 | 2026-10-22 |
| dApagliflozin SC0062 and Prevention of Renal Injury; a Randomized Evaluation Dapagliflozin (Forxiga®), SC0062 strength 10mg, SC0062 and dapagliflozin - Type 1 Diabetes Mellitus With Diabetic Nephropathy | Phase 2 | Not yet recruiting | University Medical Center Groningen | 36 | 2027-01-01 | 2026-10-20 |
| Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring. Sotagliflozin initiation - Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM) | Phase 2 | Not yet recruiting | HealthPartners Institute | 80 | 2027-01-01 | 2026-10-23 |
| Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes Resistance exercise - Type 1 Diabetes (T1D), Menopause | Not applicable | Not yet recruiting | Institut de Recherches Cliniques de Montreal | 63 | 2026-12-01 | 2026-10-01 |
| Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus Psychological Interventions for children and adolescents - Type 1 Diabetes | Not applicable | Not yet recruiting | University of Pittsburgh | 50 | 2026-12-01 | 2026-07-07 |
| Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity Tirzepatide - Type 1 Diabetes Mellitus, Overweight and Obesity | Phase 2 | Not yet recruiting | Royal North Shore Hospital | 40 | 2026-12-01 | 2025-07-29 |
| The BRIGHT Study (Device Name: HALO System) The HALO System - Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2 | Not applicable | Not yet recruiting | Indigo Diabetes NV | 12 | 2026-12-01 | 2026-08-04 |
| A Phase 2 Two-Part Study of Oral PS1 in Healthy Volunteers and Adults With Newly Diagnosed Type 1 Diabetes PS1, Placebo - Type 1 Diabetes Mellitus | Phase 2 | Not yet recruiting | Pharmasaga Co. Ltd. | 36 | 2026-11-21 | 2026-10-22 |
| Precision T1D Platform - New Therapies for Cardio-Renal Complications Finerenone, Sotagliflozin - Type 1 Diabetes, T1D Heart Failure | Phase 2 | Not yet recruiting | Oregon Health and Science University | 57 | 2026-11-01 | 2026-08-10 |
| Autologous CD6-CAR Treg Cells for Patients With Stage 3 Type 1 Diabetes AutoCD6-CAR Treg cells - Stage 3 Type 1 Diabetes | Early Phase 1 | Not yet recruiting | City of Hope Medical Center | 6 | 2026-11-01 | 2026-10-01 |
| Can Mindfulness and Virtual Reality Reduce Stress in Young Adults With Type 1 Diabetes? Mindfulness-Based Stress Reduction - Virtual Reality, Stress tip sheet - Type 1 Diabetes | Not applicable | Not yet recruiting | Wayne State University | 48 | 2026-10-31 | 2026-10-16 |
| MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT) Antiphospholipid (aPL)-Positive, Rheumatic Arthritis | Not yet recruiting | Axiom Bioregistry | 5000 | 2026-10-18 | 2026-10-23 |
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