4135 completed, 1082 unknown, 858 recruiting, 452 not yet recruiting. 4203 Not applicable, 518 Phase 2, 443 Phase 3, 400 Phase 4, 222 Phase 1.
Follow Sleep Wake Disorders: new trials by email Literature Review of Sleep Wake Disorders trials Research Report on Sleep Wake Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buddhist Awareness Training Program and Qigong Psychosocial Interventions for People With Insomnia Psychosocial intervention - Insomnia, Randomised Controlled Trial | Not applicable | Suspended | College of Professional and Continuing Education Limited | 86 | 2030-01-01 | 2026-03-19 |
| PAP Systems External Clinical Studies (ECS) PAP System A (with Amalfi) then PAP System B (with CLA11), PAP System B (with CLA11) then PAP System A (with Amalfi) - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | ResMed | 30 | 2028-08-01 | 2026-04-24 |
| Dietary Oil to Improve Sleep Quality High Linoleic Acid Healthy Cookies - Insomnia Type; Sleep Disorder | Not applicable | Not yet recruiting | Ohio State University | 16 | 2027-12-01 | 2025-12-09 |
| Effect of Music Therapy on Postoperative Health Outcomes Music therapy - Music Therapy | Not applicable | Not yet recruiting | Cairo University | 60 | 2027-12-01 | 2025-08-14 |
| Neuromodulation to Overcome Severe Restless Legs Syndrome Spinal Cord Stimulation - Restless Leg Syndrome (RLS), Spinal Cord Stimulation (SCS) | Not applicable | Not yet recruiting | Marshall Holland | 15 | 2027-10-01 | 2026-10-09 |
| Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients Opioid-free Analgesics, Opioid group - Opioid-Free Anesthesia, POCD | Not applicable | Not yet recruiting | Beijing Friendship Hospital | 88 | 2027-10-01 | 2026-10-20 |
| Grain Moxibustion Treatment on Insomnia: a Randomized Controlled Trial Grain moxibustion, Sham grain moxibustion, Standard care - Sleep Initiation and Maintenance Disorders | Not applicable | Not yet recruiting | Shanghai Institute of Acupuncture, Moxibustion and Meridian | 102 | 2027-07-01 | 2025-05-14 |
| KPAP vs EPR for Efficacy APAP + KPAP, APAP + EPR - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | SleepRes Inc. | 24 | 2027-03-01 | 2026-08-04 |
| A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems | Phase 1 / Phase 2 | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 70 | 2027-03-01 | 2026-05-04 |
| Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. Mouth Tape - Mild Obstructive Sleep Apnea, Snoring | Phase 2 | Recruiting | Johns Hopkins University | 100 | 2027-03-01 | 2026-06-23 |
| Automated vs Manual Polysomnography Scoring in Adults With Obstructive Sleep Apnea Polysomnographic Scoring (Automated vs. Manual) - Obstructive Sleep Apnea | Not yet recruiting | Ain Shams University | 50 | 2027-02-01 | 2026-09-23 | |
| Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns Bedroom Environment Tailoring, Sleep Health Education - Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) | Not applicable | Not yet recruiting | Johns Hopkins University | 40 | 2027-02-01 | 2026-10-09 |
| Efficacy of Sleep Hygiene Intervention in Elderly With Insomnia Sleep hygiene - Eelderly With Sleep Disturbances | Not applicable | Not yet recruiting | University of Pittsburgh | 100 | 2027-02-01 | 2026-03-27 |
| Randomized Trial of a Sleep Disorders Program on Firefighter Safety and Disability ... Sleep Health Education Program (SHEP) - Sleep Disorder | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 2400 | 2027-01-01 | 2026-10-13 |
| Racism-related Stress and Objective Short-sleep as Moderators of Treatment Effect in Cognitive Behavioral Therapy for Insomnia Cognitive Behavioral Therapy for Insomnia (CBTi) - Insomnia, Stress | Not applicable | Not yet recruiting | Johns Hopkins University | 100 | 2027-01-01 | 2026-09-10 |
| Web-Based Insomnia Treatment for Spousal Dementia Caregivers (SHUTi-DC) SHUTi-DC, PE - Insomnia | Not applicable | Not yet recruiting | University of Missouri-Columbia | 80 | 2027-01-01 | 2026-09-23 |
| C-LIFT Efficacy in Patients With Obstructive Sleep Apnea C-Lift - Obstructive Sleep Apnea (OSA) | Not applicable | Not yet recruiting | Ata Murat Kaynar | 10 | 2027-01-01 | 2026-09-08 |
| PAP-NAP Device Clinical Study APL Device - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | ResMed | 10 | 2027-01-01 | 2026-08-27 |
| Effects of Daily Avocado Consumption on Sleep and Skin Health in Postmenopausal Females Hass Avocado, Safflower Oil - Poor Sleep Quality | Not applicable | Not yet recruiting | San Diego State University | 74 | 2027-01-01 | 2026-10-19 |
| Sleep MAPP in the Polytrauma/TBI System of Care Sleep MAPP Care Pathway - Insomnia Disorder, Mild Traumatic Brain Injury | Not applicable | Not yet recruiting | VA Office of Research and Development | 900 | 2027-01-01 | 2026-10-21 |
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Sleep Initiation and Maintenance Disorders (2656) · Sleep Apnea, Obstructive (2155) · Sleep Apnea Syndromes (1078) · Parasomnias (648) · Depression (410) · Anxiety Disorders (387) · Sleep Deprivation (309) · Fatigue (271) · Restless Legs Syndrome (251) · Obesity (210) · Pain (203) · Disorders of Excessive Somnolence (194) · Motor Activity (173) · Hypertension (157)
Nervous System Diseases (7377) · Dyssomnias (6336) · Sleep Disorders, Intrinsic (5982) · Mental Disorders (4693) · Respiratory Tract Diseases (3062) · Respiration Disorders (2954) · Apnea (2861) · Pathological Conditions, Signs and Symptoms (2536) · Signs and Symptoms (2187) · Sleep Apnea Syndromes (1859) · Neurologic Manifestations (1535) · Behavior (956) · Pathologic Processes (583) · Nutritional and Metabolic Diseases (563)
Continuous Positive Airway Pressure (248) · Cognitive Behavioral Therapy (233) · Melatonin (90) · Polysomnography (82) · Zolpidem (81) · Exercise (70) · Eszopiclone (61) · Surveys and Questionnaires (57) · Modafinil (54) · Therapeutics (54) · ramelteon (53) · Occlusal Splints (50) · Sleep (46) · suvorexant (45) · Control Groups (39)
Brigham and Women's Hospital (98) · VA Office of Research and Development (96) · Chinese University of Hong Kong (80) · ResMed (70) · University Hospital, Grenoble (70) · Fisher and Paykel Healthcare (68) · The University of Hong Kong (66) · University of Pennsylvania (51) · Stanford University (50) · Johns Hopkins University (49) · Assistance Publique - Hôpitaux de Paris (48) · University of Michigan (46) · Massachusetts General Hospital (45) · Mayo Clinic (44) · University of California, San Diego (44)
United States (2584) · France (543) · Turkey (Türkiye) (526) · China (389) · Canada (356) · Taiwan (257) · Spain (245) · Germany (235) · United Kingdom (189) · Brazil (188) · Hong Kong (161) · Switzerland (154) · Belgium (153) · Italy (138) · Sweden (127)
Atul Malhotra, MD (10) · Dennis Hwang, MD (8) · Klaus Schindhelm, PhD (8) · Olivier Vanderveken, MD, PhD (8) · Sairam Parthasarathy, MD (8)
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2025 (17), 2023 (14), 2015 (12), 2019 (11), 2018 (7), 2005 (6), 2009 (6), 2017 (5), R01HL102321 (5), 2004 (3), 2008 (3), 2016 (3), R44HL158286 (3), 4UL1TR000427-10 (2), K23HL151880 (2)