214 completed, 61 unknown, 31 terminated, 17 recruiting. 91 Phase 4, 76 Phase 2, 72 Phase 3, 57 Not applicable, 52 Phase 1.
Follow Losartan: new trials by email Literature Review of Losartan trials Research Report on Losartan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Losartan and Paclitaxel in Platinum Resistant Ovarian Cancer losartan, Paclitaxel - Platinum Resistant Ovarian Cancer | Phase 2 | Not yet recruiting | Massachusetts General Hospital | 27 | 2027-02-01 | 2026-09-22 |
| A Phase 1 Clinical Trial to Evaluate the Safety and the Pharmacokinetic Drug-Drug Interaction Between HUC2A-752-A and HUC2A-752-B in Healthy Adults Losartan (COZZAR®), Pitavastatin plus Ezetemibe - Hypertension | Phase 1 | Not yet recruiting | Huons Co., Ltd. | 30 | 2026-10-01 | 2026-09-10 |
| The GranStone Trial empagliflozin (Jardiance) 25 mg, Losartan 100 mg - Paraffinoma, Granuloma, Foreign-Body | Phase 2 / Phase 3 | Not yet recruiting | Martin Blomberg Jensen | 100 | 2026-09-01 | 2026-09-18 |
| Combination Immunotherapy Treatment for Glioblastoma Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy BreakVax, Ipilimumab 2.5 mg, Pembrolizumab - Glioblastoma (GBM) | Phase 1 / Phase 2 | Not yet recruiting | BreakBio Corp | 10 | 2026-09-01 | 2026-08-19 |
| Combination Immunotherapy Treatment for Locally Advanced Unresectable or Metastatic, PD-L1 Negative (CPS<10), gBRCA Negative, Triple Negative Breast Cancer Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy BreakVax, Ipilimumab 2.5 mg, Pembrolizumab - Triple-Negative Breast Cancer (TNBC) | Phase 1 / Phase 2 | Not yet recruiting | BreakBio Corp | 10 | 2026-09-01 | 2026-08-19 |
| Rosuvastatin and Losartan Pharmacokinetics After Bariatric Surgery Rosuvastatin, Losartan (Control) - Obesity & Overweight, Bariatric Surgery | Not applicable | Not yet recruiting | Hospital das Clínicas de Ribeirão Preto | 60 | 2026-08-02 | 2026-08-05 |
| Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction Losartan, Placebo - ACL Injury, ACL Reconstruction | Phase 4 | Not yet recruiting | Rush University Medical Center | 144 | 2026-08-01 | 2025-12-15 |
| Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD) Finerenone, Semaglutide, Lotensin - Chronic Kidney Disease, Type 2 Diabetes | Phase 4 | Enrolling by invitation | Baylor Research Institute | 64 | 2026-04-08 | 2026-10-13 |
| Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate - Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes | Not applicable | Enrolling by invitation | Enhanced Emirates Limited | 60 | 2026-03-12 | 2026-05-06 |
| The Effect of Losartan on Cephalexin losartan, cephalexin - Possible Interaction Between Losartan and Cephalexin, Healthy | Phase 1 | Completed | Aleksi Tornio | 13 | 2026-03-04 | 2026-10-01 |
| Losartan for Corneal Fibrosis Topical losartan, Placebo Control - Corneal Scarring Fibrosis | Not applicable | Recruiting | Universidad Autonoma de Nuevo Leon | 46 | 2026-02-12 | 2026-05-08 |
| Investigation of the Effectiveness of Exercise and Anti-Fibrotic Approaches in Frozen Shoulder Patient Education, Shoulder Exercise Therapy, Losartan - Adhesive Capsulitis of Shoulder | Not applicable | Recruiting | Istanbul University | 33 | 2026-01-07 | 2026-04-07 |
| Exploration of Postoperative Adjuvant Therapy for HCC Patients With Positive TB Lenvatinib + losartan - Carcinoma, Hepatocellular | Phase 4 | Not yet recruiting | Second Affiliated Hospital of Xi'an Jiaotong University | 56 | 2025-10-01 | 2025-09-16 |
| Losartan to Improve Outcomes After Multi-ligament Knee Injury losartan 25 mg, Placebo capsule - Multi-ligament Knee Injury | Phase 2 | Recruiting | Brigham and Women's Hospital | 90 | 2025-10-01 | 2026-01-20 |
| Combined Blood Pressure Medication and Activity Scheduling for Low Mood Losartan with BA, Placebo with BA - Emotional Processing, Mood | Early Phase 1 | Recruiting | University of Oxford | 76 | 2025-07-08 | 2025-07-24 |
| Effect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgitation Undergoing Valve Surgery. Losartan 50 mg, Placebo - Heart Valve Diseases, Left Ventricle Remodeling | Phase 4 | Recruiting | Vitor Emer Egypto Rosa | 60 | 2025-07-01 | 2025-08-01 |
| Losartan and Social Processing Losartan potassium 50mg, Placebo - Social Cognition | Early Phase 1 | Completed | University of Oxford | 68 | 2024-08-19 | 2026-09-24 |
| Losartan and Emotional Learning Losartan potassium 50mg, Placebo - Emotional Processing | Early Phase 1 | Unknown | University of Oxford | 60 | 2024-08-14 | 2024-10-04 |
| Comparison of the Role of Losartan Alone vs Hydrochlorothiazide Plus Losartan Losartan, Losartan + Hydrochlorothiazide - Proteinuria | Not applicable | Unknown | RESnTEC, Institute of Research | 234 | 2024-08-01 | 2024-07-09 |
| Clinical Study Evaluating the Effect of Losartan Losartan 50mg Tab - Pancreatic Cancer | Not applicable | Completed | Tanta University | 90 | 2024-07-20 | 2026-10-05 |
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Hypertension (111) · Proteinuria (19) · Essential Hypertension (18) · Diabetic Nephropathies (17) · Diabetes Mellitus, Type 2 (16) · Kidney Diseases (14) · COVID-19 (13) · Diabetes Mellitus (11) · Cardiovascular Diseases (10) · Renal Insufficiency, Chronic (10) · Insulin Resistance (8) · Marfan Syndrome (8) · Coronavirus Infections (7) · Pancreatic Neoplasms (7) · Glomerulonephritis, IGA (6)
Organon and Co (21) · Hanmi Pharmaceutical Company Limited (12) · Merck Sharp & Dohme LLC (7) · University of Electronic Science and Technology of China (7) · University of Oxford (7) · Boehringer Ingelheim (6) · Massachusetts General Hospital (6) · Brigham and Women's Hospital (4) · Children's Hospital Medical Center, Cincinnati (4) · Daiichi Sankyo (4) · Torrent Pharmaceuticals Limited (4) · University of Minnesota (4) · Fifth Affiliated Hospital, Sun Yat-Sen University (3) · Mayo Clinic (3) · NYU Langone Health (3)
United States (115) · China (23) · South Korea (23) · Italy (15) · Brazil (14) · Canada (14) · Germany (11) · Mexico (10) · United Kingdom (10) · Spain (9) · Taiwan (9) · Denmark (8) · Netherlands (8) · India (6) · Poland (6)
Andrea Reinecke, PhD (5) · Benjamin Becker, PhD (5) · Seung-Yun Cho, M.D., Ph.D. (3) · Anna Stanhewicz, PhD (2) · Benjamin Becker, Dr (2) · Christopher Tignanelli, MD (2) · Dennis N. Morrison, D.O. (2) · Fan Fan Hou, M.D.,Ph.D. (2) · Hee Gyung Kang, Ph.D (2) · Hui M Jin, MD (2) · Italo Biaggioni, MD (2)
PMID 38682786, PMID 38299639, PMID 39082471, PMID 32658300, PMID 32905623, PMID 33586138, PMID 34473343, PMID 36398903, PMID 38770818, PMID 41486497, PMID 10851208, PMID 11593107, PMID 11927799, PMID 12119802, PMID 12923400, PMID 12937228, PMID 15738343, PMID 15851648, PMID 16281062, PMID 16391172, PMID 16533484, PMID 16601194, PMID 16988754, PMID 17130190, PMID 17188619, PMID 17324745, PMID 17533019, PMID 17911499, PMID 17978307, PMID 18335252, PMID 18426998, PMID 18475165, PMID 18496508, PMID 18653268, PMID 18670416, PMID 18930568, PMID 19047577, PMID 19073787, PMID 19430350, PMID 19571282, PMID 19571790, PMID 19571791, PMID 19628656, PMID 19738158, PMID 19922995, PMID 19932542, PMID 19949604, PMID 20142543, PMID 20147971, PMID 20619242
2023 (2), 1UG3AR077748-01 (1), 2008 (1), 2009 (1), 2015 (1), 2018 (1), 2019 (1), 2025 (1), K23HL127100 (1), P30AG021334 (1), P30CA093373 (1), P50HL084945 (1), R01AG076660 (1), R01DK060706 (1), R01HL133240 (1)