17 completed, 4 unknown, 2 terminated, 1 active not recruiting. 24 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 24 | Completed 17, Unknown 4, Terminated 2, Active not recruiting 1 |
| Phase 2 | 4 | Unknown 4 |
Follow Dementia, Vascular: new trials by email Literature Review of Dementia, Vascular trials Research Report on Dementia, Vascular
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cannabidiol's Role in Dementia Management Cannabidiol Oil - Dementia, Vascular, Dementia, Mixed | Phase 2 / Phase 3 | Unknown | Hospital Pengajar Universiti Putra Malaysia | 486 | 2024-09-01 | 2024-07-23 |
| Prospekta in the Treatment of Cognitive, Behavioral and Psychiatric Disorders in Patients With Vascular Dementia. Prospekta, Placebo - Vascular Dementia | Phase 3 | Completed | Materia Medica Holding | 406 | 2020-12-03 | 2024-10-28 |
| Dapagliflozin Effect in Cognitive Impairment in Stroke Trial Dapagliflozin 10mg Tab, Statins (Cardiovascular Agents), Platelet Antiaggregant - Stroke, Ischemic, Mild Cognitive Impairment | Phase 2 / Phase 3 | Unknown | Jaime Daniel Mondragon | 270 | 2020-08-01 | 2022-10-04 |
| Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study telmisartan 20mg + amlodipine 2.5mg +indapamide 1.25mg, Placebo oral capsule - Cognitive Decline, Intracerebral Hemorrhage | Phase 3 | Terminated | The George Institute | 1 | 2020-02-27 | 2021-04-01 |
| Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular Dementia Butylphthalide soft capsule, Placebo soft capsule - Vascular Dementia | Phase 3 | Active not recruiting | Capital Medical University | 707 | 2019-10-29 | 2026-03-23 |
| The Clinical Trial of Chinese Herbal Medicine (SaiLuoTong) Capsule SaiLuoTong capsule, placebo - Vascular Dementia | Phase 3 | Completed | Shineway Pharmaceutical Co.,Ltd | 493 | 2019-04-10 | 2026-02-17 |
| Local Study of Akatinol Memantine in VaD in Russia Akatinol Memantine 20 mg, Akatinol Memantine 10 mg - Vascular Dementia | Phase 3 | Completed | Merz Pharmaceuticals GmbH | 130 | 2018-01-23 | 2022-07-22 |
| Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis Placebo, Pimavanserin 34 mg, Pimavanserin 20 mg - Dementia-related Psychosis | Phase 3 | Completed | ACADIA Pharmaceuticals Inc. | 392 | 2017-09-27 | 2021-06-21 |
| The Healthy Patterns Sleep Study Attention-Control Condition, Timed Activity Intervention - Dementia, Alzheimer Disease | Phase 3 | Completed | University of Pennsylvania | 421 | 2016-05-01 | 2024-07-26 |
| Symptomatic Treatment of Vascular Cognitive Impairment Galantamine, Methylphenidate, Placebo - Mild Cognitive Impairment (Vascular), Mild Cognitive Disorder (Vascular) | Phase 2 / Phase 3 | Unknown | Amsterdam UMC, location VUmc | 30 | 2014-02-01 | 2016-05-02 |
| Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia Tianzhi granule and placebo identified to donepezil, Donepezil and placebo identified to Tianzhi granule, Placebo - Vascular Dementia | Phase 3 | Completed | Dongzhimen Hospital, Beijing | 543 | 2013-10-01 | 2020-01-07 |
| Evaluating the Effects of Music Interventions on Hospitalised People With Dementia Music Therapy - Dementia, Alzheimer's Disease | Phase 2 / Phase 3 | Unknown | National Ageing Research Institute, Australia | 180 | 2007-03-01 | 2007-03-16 |
| Vaspect Study - An Open-Label Trial Of Donepezil in Vascular and Mixed Dementia Donepezil - Dementia, Vascular, Dementia, Mixed | Phase 3 | Terminated | Pfizer | 149 | 2005-06-01 | 2015-03-24 |
| Dopamine Transporter Scintigraphy Imaging (DAT-Imaging) in Patients With Lewy Body Dementia DatSCAN - Lewy Body Dementia, Non-DLB Dementia | Phase 3 | Completed | GE Healthcare | 326 | 2003-11-01 | 2007-05-16 |
| Donepezil Hydrochloride (E2020) in Dementia Associated With Cerebrovascular Disease Donepezil Hydrochloride - Dementia, Vascular | Phase 3 | Completed | Eisai Inc. | 974 | 2003-03-01 | 2011-04-01 |
| Seroquel- Agitation Associated With Dementia Quetiapine Fumarate, Placebo - Alzheimer's Disease, Vascular Dementia | Phase 3 | Completed | AstraZeneca | 333 | 2002-09-01 | 2009-03-25 |
| Rivastigmine Capsules in Patients With Probable Vascular Dementia Rivastigmine - Vascular Dementia | Phase 3 | Completed | Novartis | 521 | 2002-02-01 | 2017-03-28 |
| A Placebo-controlled Trial to Evaluate the Safety and Efficacy of Galantamine in the Treatment of Vascular Dementia galantamine - Dementia, Vascular | Phase 3 | Completed | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 254 | 2001-10-01 | 2011-06-08 |
| Efficacy and Safety of Rivastigmine Capsules in Patients With Probable Vascular Dementia Rivastigmine - Vascular Dementia | Phase 3 | Completed | Novartis Pharmaceuticals | 708 | 2001-08-01 | 2011-11-17 |
| A Study of the Safety and Effectiveness of Galantamine Versus Placebo in the Treatment of Patients With Vascular Dementia or Mixed Dementia galantamine hydrobromide - Alzheimer Disease, Vascular Dementia | Phase 3 | Completed | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 593 | 1998-12-01 | 2011-05-18 |
Showing 20 of 24. Sign in to see all of them.
Dementia (11) · Alzheimer Disease (9) · Mixed Dementias (6) · Cognitive Dysfunction (4) · Lewy Body Disease (3) · Memory Disorders (3) · Neurocognitive Disorders (2) · Psychomotor Agitation (2) · Cerebral Hemorrhage (1) · Cerebral Small Vessel Diseases (1) · Chronobiology Disorders (1) · Corticobasal Degeneration (1) · Delusions (1) · Disorders of Excessive Somnolence (1)
Arterial Occlusive Diseases (24) · Arteriosclerosis (24) · Brain Diseases (24) · Cardiovascular Diseases (24) · Central Nervous System Diseases (24) · Cerebrovascular Disorders (24) · Intracranial Arterial Diseases (24) · Intracranial Arteriosclerosis (24) · Leukoencephalopathies (24) · Mental Disorders (24) · Nervous System Diseases (24) · Vascular Diseases (24) · Neurocognitive Disorders (22) · Dementia (13) · Neurodegenerative Diseases (10)
Donepezil (3) · Galantamine (3) · Risperidone (3) · Rivastigmine (2) · Amlodipine (1) · Aspirin (1) · Atorvastatin (1) · Biguanides (1) · Bromocriptine (1) · Cannabidiol (1) · Cardiovascular Agents (1) · Citalopram (1) · Clopidogrel (1) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (1) · Hypoglycemic Agents (1)
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (2) · ACADIA Pharmaceuticals Inc. (1) · Amsterdam UMC, location VUmc (1) · AstraZeneca (1) · Bruce Pollock (1) · Capital Medical University (1) · Dongzhimen Hospital, Beijing (1) · Eisai Inc. (1) · GE Healthcare (1) · Hospital Pengajar Universiti Putra Malaysia (1) · Jaime Daniel Mondragon (1) · Janssen Pharmaceutica N.V., Belgium (1) · Janssen, LP (1) · Janssen-Cilag Pty Ltd (1) · Materia Medica Holding (1)
United States (5) · China (3) · Germany (3) · Russia (3) · Australia (2) · Canada (2) · France (2) · Italy (2) · Netherlands (2) · Spain (2) · United Kingdom (2) · Austria (1) · Bulgaria (1) · Chile (1) · Czechia (1)
Bruce G. Pollock, M.D., Ph.D. (1) · Holly Posner (1) · Jianping Jia, MD,PhD (1) · Jianping Jia, Professor (1) · Jinzhou Tian, MD,PhD (1) · Jonathan B Barber, PhD (1) · Marc Pignot, PhD (1)
PMID 10084637, PMID 10496251, PMID 11965273, PMID 12633121, PMID 18674411, PMID 20204386, PMID 23040716, PMID 24993764, PMID 28095900, PMID 28950419, PMID 29016744, PMID 29371333, PMID 29446769, PMID 29559423, PMID 29573529, PMID 31236801, PMID 31248555, PMID 31535829, PMID 31910895, PMID 32054507, PMID 32115470, PMID 32144994, PMID 32178931, PMID 32317958, PMID 32352644, PMID 32559474, PMID 32854852, PMID 33030307, PMID 33282811, PMID 33853394, PMID 33894597, PMID 34289275, PMID 34344312, PMID 34813630, PMID 34934801, PMID 36791792, PMID 39498781, PMID 40049590, PMID 41286676
2017 (1), R01MH059666 (1), R01NR015226 (1)