335 completed, 208 unknown, 161 recruiting, 49 not yet recruiting. 310 Not applicable, 76 Phase 2, 63 Phase 3, 46 Phase 4, 28 Phase 1.
Follow Intracranial Arterial Diseases: new trials by email Literature Review of Intracranial Arterial Diseases trials Research Report on Intracranial Arterial Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EDAS Revascularization for Symptomatic Intracranial Atherosclerotic Steno-occlusive Disease Encephaloduroarteriosynangiosis (EDAS), Intensive medical management - Intracranial Atherosclerosis, Intracranial Arterial Stenosis | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 170 | 2027-05-01 | 2026-10-22 |
| RESCUE: PCSK9 Inhibitors for Carotid Vulnerable Plaque Remodeling Intervention 1, Intervention 3, Intervention 2 - Atherosclerosis Cerebral, Carotid Plaque | Phase 4 | Not yet recruiting | Keqiang Zhao | 120 | 2027-01-01 | 2026-09-15 |
| Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage Normal Saline, Nicardipine - Subarachnoid Hemorrhage | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 214 | 2027-01-01 | 2026-10-01 |
| Interest of a Simulated Procedure Performed on a Printed Model in the Endovascular Treatment of Carotid-sylvian Aneurysms Operational Pre-Planning - Aneurysm Cerebral | Not applicable | Not yet recruiting | University Hospital, Brest | 40 | 2026-12-01 | 2026-06-09 |
| Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy Observation - Aneurysm Cerebral | Not yet recruiting | Mayo Clinic | 100 | 2026-12-01 | 2026-01-07 | |
| Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI) Mini-mental State Examination, Addenbrooke's Cognitive Examination, Speech Task - Picture Description - Dementia (Diagnosis), Alzheimer Dementia (AD) | Not yet recruiting | Zealand University Hospital | 440 | 2026-11-01 | 2026-09-02 | |
| Surveillance Versus Treatment of Unruptured Intracranial Aneurysms of Fortuitous Discovery Clinical and imaging surveillance, Endovascular or neurosurgical aneurysm treatment - Unruptured Intracranial Aneurysm, Intracranial Aneurysm | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 600 | 2026-11-01 | 2026-09-14 |
| A Multicenter, Prospective, Double-blind, Randomized Controlled Study on the Efficacy and Safety of Ischemic Preconditioning Therapy Versus Optimal Medical Therapy in Reducing the Recurrence of Ischemic Events in Symptomatic Moyamoya Disease remote ischemic conditioning (RIC), Control - Moya Moya Disease, Moyamoya Syndrome | Not applicable | Recruiting | Beijing Tiantan Hospital | 256 | 2026-10-10 | 2026-10-22 |
| Multimodal Approach Feasability Study for Untreated and Unruptured Intracranial Aneurysms 3D CEUS - Aneurysm Cerebral (Unruptured) | Not applicable | Recruiting | Resolve Stroke | 15 | 2026-10-05 | 2026-10-13 |
| Hyperoxemia and Oxygen Reserve Index During Neurointerventional Anesthesia Oxygen Reserve Index Monitoring (Observational) - Hyperoxia, Hyperoxemia | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 100 | 2026-10-01 | 2026-10-06 | |
| Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project) AI, healthy dialogue - Stroke, Moyamoya Disease | Not applicable | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 20 | 2026-10-01 | 2026-08-28 |
| Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS) Rivaroxaban, ASA - Ischemic Stroke, Intracranial Atherosclerosis | Phase 3 | Not yet recruiting | Population Health Research Institute | 1172 | 2026-09-30 | 2026-09-01 |
| Efficacy and Safety Study of Digital Cognitive Training and PCSK9 Inhibitor-Enhanced Lipid-lowering Strategy in Patients With Intracranial Atherosclerotic Stenosis: A 2x2 Factorial, Randomized, Parallel-Group, Multicenter Trial Rosuvastatin, Ezetimibe, Recaticimab - Intracranial Arteriosclerosis, Cognitive Impairment | Phase 4 | Not yet recruiting | Peking Union Medical College Hospital | 440 | 2026-09-17 | 2026-09-15 |
| Multimodal Physiologic State Intelligence Study OMNIPHYS Multimodal Ultrasound Imaging System - Heart Failure, Cardiomyopathies | Enrolling by invitation | Truway Health, Inc. | 25000 | 2026-09-02 | 2026-09-10 | |
| PCSK9 Inhibitor for Intracranial Atherosclerosis Related Acute Ischemic Stroke Recaticimab plus standard therapy, Recaticimab's placebo in combination with standard therapy - Acute Ischemic Stroke AIS, Intracranial Atherosclerosis ICAS | Phase 4 | Not yet recruiting | Peking Union Medical College Hospital | 1212 | 2026-09-01 | 2026-07-15 |
| Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD) Transcranial Doppler (TCD) examination - Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke | Not yet recruiting | Virginia Commonwealth University | 100 | 2026-09-01 | 2026-09-14 | |
| Post-Market Active Surveillance and Health Economic Evaluation of Cerebrovascular Diagnostic and Therapeutic Devices Endovascular Treatment for Acute Ischemic Stroke - Acute Ischemic Stroke, Intracranial Arterial Stenosis | Not yet recruiting | Changhai Hospital | 2000 | 2026-09-01 | 2026-09-18 | |
| Intelligent Microcatheter Shaping for Intracranial Aneurysm Coil Embolization Physician-Experience Microcatheter Shaping, AI-Assisted Microcatheter Shaping Simulation Technology - Intracranial Aneurysm | Not yet recruiting | Xuanwu Hospital, Beijing | 1438 | 2026-08-01 | 2026-08-06 | |
| The TERUMO FRED X EARLY FEASIBILITY STUDY (FAST) STUDY. Fred X Medical Device Intervention for Aneurysm Treatment with DAPT Therapy. - Aneurysm Cerebral | Not applicable | Not yet recruiting | Jacobs institute | 15 | 2026-08-01 | 2026-08-12 |
| A Phase II Trial of Fetal Embolization for Vein of Galen Malformation Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils - Vein of Galen Malformations | Not applicable | Recruiting | Darren Orbach | 20 | 2026-07-20 | 2026-07-23 |
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Intracranial Aneurysm (390) · Dementia, Vascular (181) · Alzheimer Disease (123) · Stroke (110) · Dementia (103) · Intracranial Arteriosclerosis (98) · Cognitive Dysfunction (73) · Ischemic Stroke (71) · Aneurysm (68) · Moyamoya Disease (59) · Lewy Body Disease (55) · Subarachnoid Hemorrhage (53) · Intracranial Arteriovenous Malformations (43) · Mixed Dementias (41) · Infarction, Middle Cerebral Artery (38)
Central Nervous System Diseases (878) · Nervous System Diseases (874) · Brain Diseases (870) · Cardiovascular Diseases (870) · Vascular Diseases (869) · Cerebrovascular Disorders (859) · Arterial Occlusive Diseases (341) · Aneurysm (326) · Arteriosclerosis (284) · Pathological Conditions, Signs and Symptoms (258) · Mental Disorders (206) · Pathologic Processes (199) · Neurocognitive Disorders (192) · Leukoencephalopathies (182)
Aspirin (18) · Clopidogrel (14) · Atorvastatin (9) · Saline Solution (9) · Conservative Treatment (6) · Stents (6) · Donepezil (5) · Magnetic Resonance Imaging (5) · Rosuvastatin Calcium (5) · Ticagrelor (5) · Cilostazol (4) · Galantamine (4) · 3-n-butylphthalide (3) · Acetaminophen (3) · Angioplasty (3)
Beijing Tiantan Hospital (39) · Microvention-Terumo, Inc. (22) · Medtronic Neurovascular Clinical Affairs (17) · Stryker Neurovascular (16) · Xuanwu Hospital, Beijing (14) · Centre hospitalier de l'Université de Montréal (CHUM) (11) · Assistance Publique - Hôpitaux de Paris (10) · Capital Medical University (9) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (9) · MicroPort NeuroTech Co., Ltd. (9) · National Taiwan University Hospital (9) · Seoul National University Hospital (9) · Mayo Clinic (8) · Phenox GmbH (8) · Ton-Bridge Medical Tech. Co., Ltd (8)
United States (230) · China (207) · France (101) · Germany (64) · Canada (52) · Italy (42) · United Kingdom (38) · Spain (35) · South Korea (30) · Switzerland (27) · Netherlands (23) · Austria (20) · Australia (19) · Belgium (19) · Taiwan (19)
Jianmin Liu (12) · Jean Raymond, MD (5) · Shuo Wang, MD (5) · Michael Skrajner, MA (4) · Chuanzhi Duan, MD (3) · David Altschul, MD (3) · David Fiorella, MD (3) · Demetrius Lopes, MD (3) · Harsh Sancheti (3) · Hongqi Zhang (3) · Laurent Pierot, Prof. (3) · Michel Piotin, M.D. (3)
PMID 33447904, PMID 22163120, PMID 24849854, PMID 26089327, PMID 35292570, PMID 19556531, PMID 25502806, PMID 26391016, PMID 28304224, PMID 29335333, PMID 29948299, PMID 30095339, PMID 30297539, PMID 30735342, PMID 31308197, PMID 31359190, PMID 31379715, PMID 31566651, PMID 32878566, PMID 33055274, PMID 33189083, PMID 33199917, PMID 33224273, PMID 33236783, PMID 33272133, PMID 35143758, PMID 36375835, PMID 37652700, PMID 40049590, PMID 10084637, PMID 10356105, PMID 10496251, PMID 10634801, PMID 11001602, PMID 11462287, PMID 11498461, PMID 11965273, PMID 12040306, PMID 12414200, PMID 12568169, PMID 12633121, PMID 12651674, PMID 15255260, PMID 15364702, PMID 15526491, PMID 15718113, PMID 1580013, PMID 16282547, PMID 16336965, PMID 16418351
2023 (6), 2015 (3), R01AG056715 (2), 1RF1AG074608-01 (1), 2014 (1), 2017 (1), 2019 (1), P01HL023619 (1), R01AG011378 (1), R01AG023116 (1), R01AG043398 (1), R01AG052583 (1), R01AG055488 (1), R01AG057855 (1), R01AG061116 (1)