101 completed, 45 unknown, 42 recruiting, 10 active not recruiting. 68 Not applicable, 29 Phase 2, 24 Phase 3, 7 Phase 4, 6 Phase 1.
Follow Dementia, Vascular: new trials by email Literature Review of Dementia, Vascular trials Research Report on Dementia, Vascular
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI) Mini-mental State Examination, Addenbrooke's Cognitive Examination, Speech Task - Picture Description - Dementia (Diagnosis), Alzheimer Dementia (AD) | Not yet recruiting | Zealand University Hospital | 440 | 2026-11-01 | 2026-09-02 | |
| Safety and Efficacy of Edaravone Dexborneol Sublingual Tablets for Blood-Brain Barrier Dysfunction in CADASIL Edaravone Dexborneol Sublingual Tablets - CADASIL | Phase 2 | Not yet recruiting | Huashan Hospital | 60 | 2026-07-01 | 2026-07-09 |
| Biological Collection of the Rare Diseases of the Brain and Eye Vessels Cohort - 2 Biocollection, Neurological evaluation and Biocollection - CADASIL, Cavernous Angioma | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 600 | 2026-06-30 | 2026-06-16 |
| Making Connections Thru Music Volunteer Led Making Connections Thru Music, Staff Led Making Connections Thru Music - Dementia, Alzheimer Disease | Not applicable | Recruiting | Hopeful Aging | 196 | 2025-12-01 | 2026-09-15 |
| Neurogenetic And Hemodynamic Of Migraine Aura And Pfo Intervention - Migraine With Aura | Recruiting | Azienda Usl di Bologna | 240 | 2025-11-24 | 2026-02-11 | |
| Music Effects on Dementia Music Therapy - Dementia, Music Therapy | Not applicable | Completed | Instituto Nacional de Geriatria, Mexico | 7 | 2025-11-10 | 2026-04-21 |
| Evaluation of Cerogrin for Auricular Vagus Nerve Stimulation in Vascular Dementia or Vascular Mild Cognitive Impairment Cerogrin, Sham Device - Vascular Dementia, Mild Cognitive Impairment | Not applicable | Active not recruiting | Neurogrin Inc. | 24 | 2025-10-15 | 2026-09-18 |
| The BRAIN App (Phase 2 SBIR) The BRAIN App - Dementia, Alzheimer Disease | Not applicable | Recruiting | Hopeful Aging | 120 | 2025-05-15 | 2026-09-15 |
| Development and Validation of a Functional MRI Biomarker of Cerebral Small Vessel Dysfunction in CADASIL Functional MRI at 3T - CADASIL | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 70 | 2025-04-01 | 2025-03-05 | |
| Pulsed Electromagnetic Field Treatment With Dementia Patients ECHS AD Device - Alzheimer's Disease, Lewy Body Dementia | Not applicable | Recruiting | Herrick Medical LLC | 48 | 2025-04-01 | 2026-09-17 |
| A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster. Herpes Zoster (HZ), Vascular Dementia | Recruiting | Center for Clinical Studies, Texas | 375 | 2025-02-13 | 2025-12-11 | |
| Retinal Vessel Leakage in Cerebral Small Vessel Disease Fundus fluorescein angiography, with ultrawide field retinal imaging - Cerebral Small Vessel Diseases, Lacunar Stroke | Recruiting | University of Edinburgh | 40 | 2025-01-13 | 2026-03-04 | |
| Rifaximin SSD in Dementia Trial Rifaximin SSD 40 mg IR tablet, Placebo - Dementia Alzheimer Type, Dementia Associated With Cerebrovascular Disease | Phase 1 / Phase 2 | Recruiting | Jasmohan Bajaj | 20 | 2024-12-30 | 2026-04-03 |
| Home Tele Rehabilitation Therapy for Vascular Dementia Home telerehabilitation therapy - Dementia, Vascular, Stroke Sequelae | Not applicable | Recruiting | The Methodist Hospital Research Institute | 120 | 2024-12-14 | 2026-03-02 |
| Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults Transcranial Alternating Current Stimulation, Digital Cognitive Training - Cognitive Dysfunction, Alzheimer Disease | Not applicable | Recruiting | Universidade Federal do Rio de Janeiro | 40 | 2024-12-02 | 2024-12-13 |
| Taiwan Post-Stroke Disability Study Stroke, Dementia | Recruiting | National Taiwan University Hospital | 2000 | 2024-10-21 | 2025-05-13 | |
| Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy. Mediterranean Diet with Extra Virgin Olive Oil, Mediterranean Diet with Walnuts, Low-Fat Control Diet - Cerebral Amyloid Angiopathy, CAA - Cerebral Amyloid Angiopathy | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 86 | 2024-10-10 | 2026-09-01 | |
| Cannabidiol's Role in Dementia Management Cannabidiol Oil - Dementia, Vascular, Dementia, Mixed | Phase 2 / Phase 3 | Unknown | Hospital Pengajar Universiti Putra Malaysia | 486 | 2024-09-01 | 2024-07-23 |
| How Does Pianistic Musical Training Influence the Development of Alzheimer's Disease? Music therapy based on piano learning - Dementia of Alzheimer Type, Dementia | Not applicable | Unknown | David Franco Castellanos | 20 | 2024-06-01 | 2024-04-22 |
| All About Me: An Intervention to Ease the Transition to Long Term Care SAFE at Home - Dementia, Alzheimer Disease | Not applicable | Completed | Hopeful Aging | 51 | 2024-04-18 | 2025-04-29 |
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Alzheimer Disease (117) · Dementia (101) · Cognitive Dysfunction (65) · Lewy Body Disease (55) · Mixed Dementias (41) · CADASIL (33) · Frontotemporal Dementia (26) · Stroke (19) · Cerebral Small Vessel Diseases (17) · Memory Disorders (12) · Disease (10) · Parkinson Disease (10) · Neurocognitive Disorders (9) · Neurodegenerative Diseases (7)
Cardiovascular Diseases (211) · Central Nervous System Diseases (211) · Intracranial Arterial Diseases (211) · Vascular Diseases (211) · Brain Diseases (210) · Nervous System Diseases (209) · Cerebrovascular Disorders (207) · Mental Disorders (184) · Arterial Occlusive Diseases (182) · Arteriosclerosis (181) · Intracranial Arteriosclerosis (181) · Leukoencephalopathies (181) · Neurocognitive Disorders (175) · Neurodegenerative Diseases (119) · Tauopathies (116)
Donepezil (5) · Galantamine (4) · Music Therapy (3) · Risperidone (3) · Transcranial Direct Current Stimulation (3) · Acetaminophen (2) · Amlodipine (2) · Aspirin (2) · Atorvastatin (2) · Blood Specimen Collection (2) · Cilostazol (2) · Hematologic Tests (2) · Indapamide (2) · Methods (2) · Neuropsychological Tests (2)
Hopeful Aging (6) · Dongzhimen Hospital, Beijing (5) · Mayo Clinic (5) · University of Pennsylvania (5) · Assistance Publique - Hôpitaux de Paris (4) · National Taiwan University Hospital (4) · University Health Network, Toronto (4) · University of California, San Francisco (4) · Eisai Inc. (3) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (3) · Skane University Hospital (3) · University College, London (3) · Capital Medical University (2) · Centre Hospitalier Universitaire, Amiens (2) · Children's Hospital of Philadelphia (2)
United States (71) · China (21) · United Kingdom (12) · France (11) · Germany (11) · Italy (11) · Australia (8) · Canada (8) · Netherlands (6) · Spain (6) · Taiwan (6) · Norway (4) · Russia (4) · South Korea (4) · Denmark (3)
Michael Skrajner, MA (4) · Adeline Vanderver, MD (2) · Aimee Spector, PhD, DClinPsych (2) · Erik Stomrud, MD, PhD (2) · Jeffrey Weiss, MD (2) · Katherine L Possin, PhD (2) · Steven E Arnold, MD (2) · Steven Levy, MD (2) · A. M. Barrett, MD (1) · Aimee Spector, PhD, DClinPsy (1) · Albert Puig-Pijoan, MD (1)
PMID 31566651, PMID 33189083, PMID 37652700, PMID 40049590, PMID 10084637, PMID 10356105, PMID 10496251, PMID 11001602, PMID 11965273, PMID 12040306, PMID 12633121, PMID 15364702, PMID 18674411, PMID 19347838, PMID 19500421, PMID 19891819, PMID 19933977, PMID 20204386, PMID 20386637, PMID 20656516, PMID 20880607, PMID 20930266, PMID 21118724, PMID 21908805, PMID 22123780, PMID 22133740, PMID 22228824, PMID 22340708, PMID 22398564, PMID 22503900, PMID 22503901, PMID 22922216, PMID 22930700, PMID 23040716, PMID 23103091, PMID 23172761, PMID 23785466, PMID 23867200, PMID 23871765, PMID 23872925, PMID 23911592, PMID 23957255, PMID 24009169, PMID 24175165, PMID 24418053, PMID 24578207, PMID 24761653, PMID 24969152, PMID 24993764, PMID 25044107
R01AG056715 (2), 1RF1AG074608-01 (1), 2015 (1), 2017 (1), R01AG011378 (1), R01AG023116 (1), R01AG043398 (1), R01AG052583 (1), R01AG055488 (1), R01AG057855 (1), R01AG061116 (1), R01AG065394 (1), R01AG074710 (1), R01AG078169 (1), R01AG085406 (1)