24 completed, 12 unknown, 4 recruiting, 2 not yet recruiting. 10 Phase 4, 9 Phase 3, 7 Phase 2, 5 Not applicable, 3 Phase 1.
Follow Hypoglycemic Agents: new trials by email Literature Review of Hypoglycemic Agents trials Research Report on Hypoglycemic Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GLP1 Analogues and the Risk of Osteoarthritis GLP-1 analog, SGLT2 inhibitor, Antidiabetic - Osteoarthritis | Not yet recruiting | Beni-Suef University | 390 | 2026-02-01 | 2026-01-22 | |
| Active Anti-diabetic Treatment Plus Chemotherapy for Pancreatic Cancer Related Diabetes Nab-paclitaxel, Gemcitabine (1000 mg/m2), Anti-Diabetics - Pancreatic Cancer | Phase 3 | Not yet recruiting | Fudan University | 210 | 2026-01-01 | 2025-12-15 |
| Lactoferrin Supplementation in Diabetic Nephropathy Lactoferrin, Antidiabetic, Placebo - Diabetic Nephropathy | Phase 2 | Recruiting | Ain Shams University | 60 | 2025-08-01 | 2026-08-14 |
| Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause Hyperbaric oxygen therapy, Hypoglycemic Drug - Insulin Resistance Syndrome | Phase 1 / Phase 2 | Recruiting | Cairo University | 40 | 2025-01-28 | 2025-02-04 |
| Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction Dapagliflozin 10 mg once daily, Loop diuretics, Treatments of associated co-morbidities (e.g Anti-hypertensive, oral hypoglycemic) - Heart Failure with Preserved Ejection Fraction | Not applicable | Unknown | Aswan University | 70 | 2024-08-01 | 2024-07-19 |
| Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls Fresh normal pancreatic tissues or adjacent tissues of pancreatic cancer were collected from controls and T2DM patients without hypoglycemic drugs, Fresh blood samples were collected from healthy subjects and T2DM patients without hypoglycemic drugs - Type 2 Diabetes Mellitus, Gene Polymorphisms | Not applicable | Recruiting | The Affiliated Hospital of Xuzhou Medical University | 300 | 2024-01-01 | 2024-02-28 |
| Effect of DM on Outcomes and Response Rate in Patients With Advanced NSCLC on ICI Pembrolizumab - Non Small Cell Lung Cancer Metastatic, Diabetes Mellitus | Unknown | Assiut University | 60 | 2023-10-01 | 2023-10-25 | |
| "How Awareness and Subjectivity Modulate the Placebo Effect" Neutral ginger-flavored drink described as energizing, hypoglycemic, caffeine-based drink, Neutral ginger-flavored drink - 3 Placebo Groups in a Cycle Ergometer Session With Healthy Participants | Not applicable | Recruiting | Fondazione Don Carlo Gnocchi ETS | 84 | 2022-11-28 | 2024-11-12 |
| THE Effect of Tight Glycemic Control on Microvascular Complications in Type 2 Diabetes Mellitus Insulin Therapy, Antidiabetic therapy, lifestyle modification - Diabetes Mellitus | Not applicable | Completed | Ain Shams University | 80 | 2022-05-11 | 2025-07-03 |
| TEsting METformin Against Cognitive Decline in HD Metformin, Placebo - Huntington Disease | Phase 3 | Completed | Instituto de Investigacion Sanitaria La Fe | 60 | 2022-04-11 | 2025-09-25 |
| A Clinical Study on the Effect of Hypoglycemic Drugs on the Prognosis of Spinal Surgery in Diabetic Patients Hypoglycemic Drugs - Diabetes Mellitus, Spinal Diseases | Unknown | Xijing Hospital | 124 | 2022-02-07 | 2022-06-16 | |
| A Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes Dulaglutide, Oral antihyperglycemics - Diabetes Mellitus, Diabetes Mellitus, Type 2 | Phase 3 | Completed | Eli Lilly and Company | 591 | 2021-04-13 | 2024-05-22 |
| The Impact of Glucotoxicity on Gastric Emptying in Chinese Patients With Newly Diagnosed Type 2 Diabetes Anti-Diabetics - Type 2 Diabetes | Completed | University of Adelaide | 78 | 2021-01-24 | 2024-05-09 | |
| Dapagliflozin Effect in Cognitive Impairment in Stroke Trial Dapagliflozin 10mg Tab, Statins (Cardiovascular Agents), Platelet Antiaggregant - Stroke, Ischemic, Mild Cognitive Impairment | Phase 2 / Phase 3 | Unknown | Jaime Daniel Mondragon | 270 | 2020-08-01 | 2022-10-04 |
| Effect of Glucocorticoid on Exogenous Insulin Antibody Syndrome Prednisone - Diabetes Mellitus, Type 2 | Early Phase 1 | Unknown | chenfengling | 20 | 2020-05-20 | 2020-04-24 |
| Magnesium Supplementation in Diabetic Nephropathy Magnesium citrate, Antidiabetic - Diabetic Nephropathies | Phase 2 | Completed | Ain Shams University | 60 | 2019-06-01 | 2021-01-12 |
| Efficacy of Black Seed Oil in Patients With Type 2 Diabetes Mellitus Black Seed Oil, Anti-Diabetics - Diabetes Mellitus, Type 2 | Phase 2 | Unknown | Ain Shams University | 50 | 2019-04-24 | 2019-05-22 |
| Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial Diabetes Medicines, Dapagliflozin - Type 2 Diabetes Mellitus | Phase 4 | Completed | Mackay Memorial Hospital | 76 | 2019-04-01 | 2023-03-22 |
| Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients Niacinamide Oral Tablet, Antidiabetic - Non Alcoholic Fatty Liver Disease | Phase 2 | Completed | Ain Shams University | 61 | 2019-01-15 | 2020-01-22 |
| Effect of Empagliflozin on Body Composition and Ketones Empagliflozin 10 MG, Hypoglycemics Oral - Diabetes Mellitus, Fat; Intolerance, Pancreas | Phase 4 | Unknown | Seoul National University Bundang Hospital | 200 | 2018-08-01 | 2023-08-14 |
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Diabetes Mellitus, Type 2 (18) · Diabetes Mellitus (8) · Metabolic Syndrome (4) · Insulin Resistance (3) · Atherosclerosis (2) · Cardiovascular Diseases (2) · Coronary Artery Disease (2) · Coronary Disease (2) · Diabetic Nephropathies (2) · Heart Failure (2) · Hypercholesterolemia (2) · Pancreatic Neoplasms (2) · Angina Pectoris (1) · Astrocytoma (1) · Brain Neoplasms (1)
Ain Shams University (5) · Canadian Network for Observational Drug Effect Studies, CNODES (3) · Sanofi (3) · All India Institute of Medical Sciences, Bhubaneswar (2) · AdventHealth Translational Research Institute (1) · Assiut University (1) · Aswan University (1) · Beni-Suef University (1) · Boehringer Ingelheim (1) · Cairo University (1) · Eli Lilly and Company (1) · Federico II University (1) · Fondazione Don Carlo Gnocchi ETS (1) · Fudan University (1) · IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy (1)
Egypt (7) · Canada (6) · Italy (6) · China (5) · United States (5) · Germany (3) · Australia (2) · India (2) · Israel (2) · Japan (2) · South Korea (2) · Spain (2) · Switzerland (2) · United Kingdom (2) · Austria (1)
Pierre Ernst, MD, MSc (3) · Alper Celik, MD (1) · Ann V. Schwartz, PhD (1) · Anthony P Sunjaya (1) · Asmaa Elsayed (1) · Christian Meyer, MD (1) · Debapriya Bandyopadhyay, M.D. (1) · Doaa Ali Gamal (1) · Emily Y. Chew, MD (1)
PMID 31706300, PMID 33078867, PMID 11868855, PMID 16374671, PMID 17313713, PMID 20068583, PMID 20204386, PMID 20212201, PMID 20587587, PMID 21654091, PMID 22709833, PMID 22723583, PMID 23040716, PMID 24305963, PMID 24438170, PMID 25172198, PMID 26305617, PMID 26888382, PMID 27007958, PMID 27289122, PMID 27479930, PMID 28095900, PMID 28545518, PMID 28905478, PMID 28950419, PMID 29016744, PMID 29371333, PMID 29436756, PMID 29446769, PMID 29573529, PMID 30246799, PMID 31002414, PMID 31236801, PMID 31248555, PMID 31535829, PMID 32035487, PMID 32115470, PMID 32144994, PMID 32178931, PMID 32317958, PMID 32352644, PMID 32559474, PMID 32574226, PMID 32854852, PMID 33030307, PMID 33282811, PMID 33894597, PMID 34813630, PMID 35222903, PMID 36975019
2015 (2), N01HC095178 (1)