25 completed, 21 recruiting, 6 active not recruiting, 5 unknown. 17 Not applicable, 6 Phase 2, 4 Phase 1, 1 Early Phase 1, 1 Phase 3.
Follow Corticobasal Degeneration: new trials by email Literature Review of Corticobasal Degeneration trials Research Report on Corticobasal Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Wearable Sensor Platform for Remote Monitoring of Individuals on the Frontotemporal Dementia Spectrum Frontotemporal Lobar Degeneration (FTLD), Frontotemporal Dementia (FTD) | Not yet recruiting | BioSensics | 60 | 2026-11-01 | 2026-10-13 | |
| A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of NIO752 in Primary Tauopathies NIO752, Placebo - Progressive Supranuclear Palsy, Corticobasal Degeneration | Phase 2 | Not yet recruiting | Novartis Pharmaceuticals | 48 | 2026-10-23 | 2026-10-09 |
| Digital Measurements of Motor and Voice Functions in FTD Frontotemporal Lobar Degeneration (FTLD), Frontotemporal Dementia (FTD) | Not yet recruiting | BioSensics | 20 | 2026-08-01 | 2026-04-28 | |
| Wellness in PSP and CBD Exercise and Peer Support - Progressive Supranuclear Palsy, Corticobasal Degeneration | Not applicable | Recruiting | Silke Cresswell | 30 | 2026-04-10 | 2026-09-28 |
| Research Study for Patients With Neurological Diseases Which Evaluates the Patient Experience of the MemorEM Device MemorEM - Alzheimer Disease, Parkinson Disease | Not applicable | Enrolling by invitation | eQ8Health Corporation d/b/a CareONE Concierge | 1000 | 2025-12-01 | 2026-02-05 |
| Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH) We did not apply any interventions; only observational research was conducted. - Multiple System Atrophy, Dementia With Lewy Bodies (DLB) | Recruiting | Second Affiliated Hospital of Soochow University | 500 | 2025-11-12 | 2026-09-08 | |
| tDCS as Treatment for Motor Function Transcranial direct current stimulation (TDCS), Stimulation Arm - Progressive Supranuclear Palsy, Cortical Basal Ganglionic Degeneration | Not applicable | Recruiting | Baycrest | 20 | 2025-10-30 | 2025-12-18 |
| Pilot Trial Evaluating Patient Experience With the MemorEM for Patients With Neurological Diseases MemorEM - Alzheimer's Disease, Fronto-temporal Dementia | Not applicable | Enrolling by invitation | NeuroEM Therapeutics, Inc. | 100 | 2025-07-31 | 2025-08-05 |
| Imaging Studies in Corticobasal Syndrome C-11 ER176 Radiotracer, C-11 PiB, AV1451 Tau - Cortico Basal Degeneration, Corticobasal Syndrome | Recruiting | Jennifer Whitwell | 80 | 2025-06-25 | 2026-07-14 | |
| STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners STELLA-FTD Control, STELLA-FTD Test - Frontotemporal Dementia, Caregiver Burden | Not applicable | Recruiting | Oregon Health and Science University | 640 | 2025-06-23 | 2025-10-27 |
| Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A 18F-JSS20-183A PET, Brain MRI, Amyloid PET - Tauopathies | Early Phase 1 | Recruiting | University of Pennsylvania | 90 | 2025-05-09 | 2025-12-23 |
| The CurePSP Genetics Program Whole genome sequencing will be performed at the NIH - PSP, PSP - Progressive Supranuclear Palsy | Recruiting | Massachusetts General Hospital | 1000 | 2024-10-08 | 2026-01-14 | |
| Neurodegenerative Diseases Progression Markers (MARKERS-NDD) Observation - Neurodegenerative Diseases, Parkinson Disease | Recruiting | Casa di Cura San Raffaele Cassino | 600 | 2024-09-09 | 2026-09-02 | |
| AI-Enhanced Optimization of Acute Levodopa Challenge Test video recording - Vascular Parkinsonism, Drug-induced Parkinsonism | Recruiting | Beijing Tiantan Hospital | 2000 | 2024-05-28 | 2025-04-29 | |
| Scrambler Therapy for Corticobasal Syndrome-Associated Pain Scrambler therapy, TENS treatment - Corticobasal Degeneration, Corticobasal Syndrome | Not applicable | Recruiting | Johns Hopkins University | 25 | 2024-04-05 | 2026-01-13 |
| The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders CUE1 non-invasive device, CUE1+ device active vs sham CUE1+ device - Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy | Not applicable | Recruiting | Queen Mary University of London | 70 | 2024-03-25 | 2024-11-21 |
| The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism Nicotinamide Riboside, Placebo - Progressive Supranuclear Palsy, Multiple System Atrophy | Phase 2 | Recruiting | Haukeland University Hospital | 330 | 2024-03-05 | 2025-01-10 |
| PROFIL Study to Investigate the Effect of GPB on NfL Levels in Patients With Corticobasal Syndrome (CBS) RAVICTI 1.1 g/ml, Placebo - Corticobasal Syndrome (CBS) | Phase 2 | Completed | Technical University of Munich | 32 | 2023-12-12 | 2026-09-11 |
| Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling Dementia, Alzheimer Disease | Recruiting | University Health Network, Toronto | 500 | 2023-11-11 | 2025-11-20 | |
| A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes PAMSys, LEGSys - PSP, CBD | Active not recruiting | Massachusetts General Hospital | 60 | 2023-07-28 | 2026-01-21 |
Showing 20 of 63. Sign in to see all of them.
Supranuclear Palsy, Progressive (49) · Parkinson Disease (23) · Multiple System Atrophy (22) · Lewy Body Disease (19) · Frontotemporal Dementia (18) · Alzheimer Disease (14) · Parkinsonian Disorders (12) · Frontotemporal Lobar Degeneration (10) · Dementia (9) · Amyotrophic Lateral Sclerosis (8) · Pick Disease of the Brain (7) · Aphasia, Primary Progressive (6) · Dementia, Vascular (5) · Primary Progressive Nonfluent Aphasia (5)
Nervous System Diseases (63) · Neurodegenerative Diseases (60) · Central Nervous System Diseases (59) · Tauopathies (59) · Brain Diseases (58) · Pathological Conditions, Signs and Symptoms (55) · Neurologic Manifestations (54) · Signs and Symptoms (54) · Basal Ganglia Diseases (52) · Eye Diseases (50) · Cranial Nerve Diseases (49) · Movement Disorders (49) · Ocular Motility Disorders (49) · Ophthalmoplegia (49) · Paralysis (49)
Observation (4) · Transcranial Direct Current Stimulation (2) · 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole (1) · Amantadine (1) · Apomorphine (1) · Blood Specimen Collection (1) · Deep Brain Stimulation (1) · Exercise (1) · Lithium (1) · Magnetic Resonance Imaging (1) · Palliative Care (1) · Positron-Emission Tomography (1) · Pramipexole (1) · Speech Therapy (1) · Standard of Care (1)
University of California, San Francisco (6) · BioSensics (2) · Johns Hopkins University (2) · Massachusetts General Hospital (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · Skane University Hospital (2) · University Health Network, Toronto (2) · University of California, Los Angeles (2) · University of Colorado, Denver (2) · University of Pennsylvania (2) · ACADIA Pharmaceuticals Inc. (1) · Amoneta Diagnostics SAS (1) · Avid Radiopharmaceuticals (1) · Bastyr University (1) · Baycrest (1)
United States (37) · Canada (7) · United Kingdom (6) · Italy (4) · France (3) · China (2) · Germany (2) · Sweden (2) · Belgium (1) · Bulgaria (1) · Chile (1) · Czechia (1) · Finland (1) · Ireland (1) · Israel (1)
Adam Boxer, MD, PhD (3) · Adam L Boxer, MD, PhD (2) · Alexander Pantelyat, MD (2) · Maria C Tartaglia, M.D. (2) · Adam L. Boxer, M.D., Ph.D. (1) · Adrian Ivanoiu, MD (1) · Aimee Mooney, MA, CCC-SLP (1) · Alastair Noyce, PhD (1) · Allan Wu, M.D. (1) · Allison Lindauer, PhD, APRN (1) · Andrew Feigin, MD (1) · Audrey Gabelle, MD (1) · Benzi Kluger, MD (1) · Benzi M Kluger, MD, MS (1) · Boyd CP Ghosh, MBBS (1)
PMID 35790423, PMID 31710340, PMID 33827960, PMID 34006157, PMID 34289275, PMID 34489348, PMID 34934801, PMID 34937781, PMID 35492244, PMID 37838080, PMID 37955923, PMID 38578117, PMID 38959435, PMID 39894518, PMID 40288787, PMID 40567948, PMID 40754329, PMID 41286676, PMID 41812391, PMID 41864233, PMID 42399256, PMID 42400090, PMID 42418748, PMID 42875788, PMID 42876454
1RF1AG050967-01A1 (1), 2017 (1), 2023 (1), P01AG066597 (1), R01AG031278 (1), R01AG038791 (1), R01AG054519 (1), R01AG084523 (1), R01AG087140 (1), R01NR016037 (1), U01NS112010 (1), U19AG063911 (1), U54NS092089 (1)