29 terminated. 29 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 29 | Terminated 29 |
| Phase 2 | 7 | Terminated 7 |
Follow Behavioral Symptoms: new trials by email Literature Review of Behavioral Symptoms trials Research Report on Behavioral Symptoms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alexithymia Intervention for Suicide Affective Awareness - Suicide, Schizophrenia | Phase 1 | Terminated | VA Office of Research and Development | 11 | 2023-10-01 | 2026-03-27 |
| [11C]-(R)-Rolipram to Measure cAMP Signaling Before and After Ketamine 11(R)-rolipram - Depression | Phase 1 | Terminated | National Institute of Mental Health (NIMH) | 1 | 2023-02-08 | 2024-03-05 |
| Ketamine Infusion for Rapid Reduction of Suicidality in Pediatrics Ketamine Injectable Solution, Midazolam Injectable Solution, Normal Saline 0.9% Injectable Solution - Suicidal Ideation | Phase 1 / Phase 2 | Terminated | University of British Columbia | 15 | 2022-06-01 | 2024-12-18 |
| Tofacitinib in Depression (TIDE) Tofacitinib 5 MG [Xeljanz], Placebo - Depression, Inflammation | Phase 1 / Phase 2 | Terminated | University of Oxford | 2 | 2020-02-10 | 2022-08-09 |
| Ketamine Interleaved With Electroconvulsive Therapy for Depression Ketamine, Midazolam - Depression | Phase 1 | Terminated | St Patrick's Hospital, Ireland | 3 | 2020-01-06 | 2021-09-09 |
| Trial of OnabotulinumtoxinA for Depression in Parkinson Disease OnabotulinumtoxinA, Control - Parkinson Disease, Depression | Phase 1 | Terminated | Johns Hopkins University | 3 | 2018-11-01 | 2019-08-06 |
| Allogeneic Human Mesenchymal Stem Cells (hMSCs) Infusion in Patients With Treatment Resistant Depression Allo-hMSCs, Placebo - Treatment Resistant Depression | Phase 1 | Terminated | Joshua M Hare | 1 | 2017-10-31 | 2019-04-01 |
| Brief Stresses Experimental Study Propranolol, Placebo oral capsule, Acute stress task - DNA Damage, Psychological Stress | Phase 1 | Terminated | Dana Bovbjerg | 239 | 2017-10-05 | 2023-07-18 |
| Ketamine for Relapse Prevention in Recurrent Depressive Disorder Ketamine, Midazolam - Depression, Relapse | Phase 1 | Terminated | St Patrick's Hospital, Ireland | 9 | 2015-12-01 | 2020-01-13 |
| The Therapeutic Effect of Transcranial Direct Current Stimulation on Depression in Parkinson's Disease active tDCS, Sertraline, sham tDCS - Parkinson Disease, Depression | Phase 1 / Phase 2 | Terminated | National Cheng-Kung University Hospital | 15 | 2015-08-01 | 2021-10-20 |
| The Better Resiliency Among Veterans With Omega-3's (BRAVO) Study Study Juice, Placebo Juice - Suicide | Phase 1 | Terminated | Medical University of South Carolina | 125 | 2014-03-01 | 2018-06-12 |
| Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression? Diazoxide, Placebo - Depression | Phase 1 / Phase 2 | Terminated | National Institute of Mental Health (NIMH) | 10 | 2014-01-03 | 2017-10-13 |
| Dyadic Therapy for Mothers and Children Child Parent Psychotherapy (CPP), Control (usual treatment) - Depression, Behavioral Problems | Phase 1 | Terminated | New York State Psychiatric Institute | 2 | 2013-11-01 | 2017-08-22 |
| Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G) Glycopyrrolate - Hyperhydrosis, Depression | Phase 1 | Terminated | Thomas Jefferson University | 5 | 2012-04-01 | 2016-08-25 |
| Comparison of a Drug and Placebo in the Prevention of Migraine Headaches ethosuximide, placebo comparator - Headache, Migraine | Phase 1 / Phase 2 | Terminated | US Department of Veterans Affairs | 5 | 2011-12-01 | 2015-08-19 |
| Subanesthetic IV Bolus Ketamine in the Treatment of Acute Depression Ketamine, Placebo - Acute Depression | Phase 1 | Terminated | United States Naval Medical Center, San Diego | 20 | 2011-12-01 | 2015-03-04 |
| Teens Coping With Parental Military Deployment Cognitive Behavioral Group Therapy, Nondirective supportive group therapy - Emotional Distress, Behavior Problems | Phase 1 | Terminated | Brown University | 6 | 2011-01-01 | 2013-07-04 |
| Does an Integrative Neuro-psychotherapy Program Foster the Adjustment in Depressed Stroke Patients? A Randomized Controlled Study. Neuropsychological Therapy, cognitive behavioral therapy, solution focused therapy, Integrative Neuro-Psychotherapy - Adjustment Disorders, Non-progressive Brain Injury | Phase 1 | Terminated | University of Bern | 25 | 2010-01-01 | 2015-07-10 |
| A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography) PF-04455242 - Bipolar Disorder, Depression | Phase 1 | Terminated | Pfizer | 12 | 2009-09-01 | 2010-02-08 |
| A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol Escitalopram Pill, Venlafaxine Pill, Placebo Oral Tablet - Alzheimer Disease | Phase 1 | Terminated | NYU Langone Health | 5 | 2009-06-18 | 2020-06-02 |
Showing 20 of 29. Sign in to see all of them.
Depression (23) · Depressive Disorder, Major (3) · Inflammation (3) · Anxiety Disorders (2) · Bipolar Disorder (2) · Depressive Disorder (2) · Depressive Disorder, Treatment-Resistant (2) · Parkinson Disease (2) · Stress, Psychological (2) · Suicidal Ideation (2) · Suicide (2) · Acute Coronary Syndrome (1) · Adjustment Disorders (1) · Alzheimer Disease (1) · Burns (1)
Behavior (29) · Mental Disorders (10) · Pathological Conditions, Signs and Symptoms (9) · Nervous System Diseases (6) · Brain Diseases (5) · Central Nervous System Diseases (5) · Mood Disorders (5) · Pathologic Processes (5) · Signs and Symptoms (4) · Neurodegenerative Diseases (3) · Self-Injurious Behavior (3) · Basal Ganglia Diseases (2) · Bipolar and Related Disorders (2) · Cardiovascular Diseases (2)
Ketamine (3) · Cognitive Behavioral Therapy (2) · Midazolam (2) · Saline Solution (2) · Sertraline (2) · 2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (1) · Botulinum Toxins, Type A (1) · Diazoxide (1) · Escitalopram (1) · Ethosuximide (1) · Glycopyrrolate (1) · Melatonin (1) · Propranolol (1) · Simvastatin (1) · Transcranial Magnetic Stimulation (1)
National Institute of Mental Health (NIMH) (2) · New York State Psychiatric Institute (2) · St Patrick's Hospital, Ireland (2) · Brown University (1) · Dana Bovbjerg (1) · Institute for Neurodegenerative Disorders (1) · Johns Hopkins University (1) · Joshua M Hare (1) · Medical University of South Carolina (1) · MetroHealth Medical Center (1) · NYU Langone Health (1) · National Cheng-Kung University Hospital (1) · Northstar Neuroscience (1) · Norwegian University of Science and Technology (1) · Pfizer (1)
United States (21) · Ireland (2) · Australia (1) · Canada (1) · Norway (1) · Switzerland (1) · United Kingdom (1)
Alexander Pantelyat, MD (1) · Andrew Gerber, MD (1) · Anthony Spirito, PhD (1) · Archana Basu, PhD (1) · Are Holen, PhD MD (1) · Barry Reisberg (1) · Bernadette Marriott, PhD (1) · Carlos A Zarate, M.D. (1) · Catherine Monk, PhD (1) · Charles J Yowler, MD, FACS (1) · Colleen Loo, FRANZCP; MD (1) · Dana Bovbjerg, PhD (1) · Daniel F Kripke, MD (1) · Danna L. Jennings, MD (1) · Declan McLoughlin (1)
PMID 16630205, PMID 33884617, PMID 42234079
2015 (1), R01CA211371 (1), R34MH077503 (1), R34MH082164 (1)