124 completed, 46 unknown, 15 terminated, 14 recruiting. 215 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 215 | Completed 124, Unknown 46, Terminated 15, Recruiting 14, Not yet recruiting 10, Withdrawn 5, Active not recruiting 1 |
Follow Anesthesia: new trials by email Literature Review of Anesthesia trials Research Report on Anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Use of Remimazolam for TEE Remimazolam, Propofol - Cardiac Disease, Anesthesia | Phase 4 | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 210 | 2026-09-01 | 2026-09-21 |
| Influence of Lidocaine Infusion on Motor Evoked Potential Thresholds Lidocaine in Saline, Normal saline - Spinal Disease, Anesthesia | Phase 4 | Not yet recruiting | Dartmouth-Hitchcock Medical Center | 44 | 2026-08-01 | 2025-11-24 |
| Ciprofol and Remimazolam for Intraoperative Neurophysiological Monitoring During Spine Surgery Ciprofol, Remimazolam - Intraoperative Neurophysiological Monitoring, Spine Surgery | Phase 4 | Not yet recruiting | Affiliated 2 Hospital of Nantong University | 60 | 2026-08-01 | 2026-07-21 |
| Oliceridine vs Sufentanil for Cough During Anesthesia Induction Oliceridine, Sufentanil - Cough, Anesthesia | Phase 4 | Recruiting | Shiyou Wei | 62 | 2026-06-27 | 2026-07-21 |
| The Effects of Different Anesthetics on the Brain's Neural Networks propofol, Dexmeditomidine, Esketamine - Electroencephalogram (EEG), Anesthesia | Phase 4 | Not yet recruiting | Fudan University | 120 | 2026-06-09 | 2026-06-12 |
| Comparing Spinal Anesthesia With 1% Chloroprocaine Versus 1% Mepivacaine in Patients Undergoing Outpatient Primary Total Knee Arthroplasty Mepivacaine Injection, Chloroprocaine Injection - Recovery Period, Anesthesia | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 170 | 2026-03-31 | 2026-02-06 |
| A Randomized, Controlled Clinical Trial Comparing Remimazolam Besylate Combined With Alfentanil Versus Propofol Combined With Alfentanil for Anesthesia in Thoracic Surgery Remimazolam Besylate for Injection, Propofol, Alfentanil Hydrochloride Injection - Thoracic Surgery, Anesthesia | Phase 4 | Not yet recruiting | The First Affiliated Hospital of Xinxiang Medical College | 50 | 2026-03-01 | 2026-01-16 |
| Spinal Morphine and Atropine Added to General Anaesthesia for Nausea and Pain After Abdominal Laparoscopy Intrathecal bupivacaine, morphine and atropine, General anaesthesia, Multimodal analgesia and antiemetic prophylaxis - Postoperative Nausea and Vomiting, Postoperative Pain | Phase 4 | Completed | Universitas Indonesia | 63 | 2026-02-02 | 2026-10-01 |
| Oral Methadone in Cardiac Surgery Methadone, oral, Methadone, intravenously - Pain, Postoperative, Anesthesia | Phase 4 | Completed | Mayo Clinic | 100 | 2026-01-13 | 2026-10-28 |
| Effect of Itopride on Semaglutide Gastroparesis Itopride HCI 50 mg, Placebo - Semaglutide-Induced Gastric Motility, Anesthesia | Phase 4 | Completed | Ain Shams University | 60 | 2026-01-01 | 2026-09-25 |
| MR-Evaluation of Renal Function in Anesthetized Pediatric Patients Anesthesia Maintenance Agent - Renal Blood Flow, Anesthesia | Phase 4 | Not yet recruiting | Uppsala University | 50 | 2025-10-01 | 2025-03-25 |
| Veterans Enhanced Recovery Using Integrative Treatments Around Surgery Nonpharmacologic Treatment, Standard Care - Anesthesia, Surgery | Phase 4 | Not yet recruiting | Durham VA Medical Center | 400 | 2025-09-01 | 2025-05-01 |
| Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4 Randomization of Propofol or Dexmedetomidine - Anesthesia; Reaction, Anesthesia | Phase 4 | Not yet recruiting | Children's Hospital Los Angeles | 130 | 2025-09-01 | 2025-08-05 |
| CORA-Q15: Continuous vs. Single-injection Interscalene Block on QoR-15 in Outpatient Rotator Cuff Surgery Continuous perineural infusion, Single injection - Arthropathy Shoulder, Pain, Acute | Phase 4 | Recruiting | Pontificia Universidad Catolica de Chile | 150 | 2025-05-26 | 2025-05-30 |
| Pharmacokinetic Study of Intravenous Lidocaine in Young and Elderly Patients Pre-inclusion, Inclusion, Lidocaine - Anesthesia | Phase 4 | Completed | Rennes University Hospital | 67 | 2025-04-28 | 2026-06-12 |
| Oral and Intravenous Methadone for Analgesia in Cardiac Surgery Oral methadone, immediately prior to transport, Intravenous methadone - Anesthesia, Cardiac Surgery | Phase 4 | Completed | Mayo Clinic | 41 | 2025-04-14 | 2026-08-06 |
| The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery Norepinephrine, Phenylephrine - Anesthesia, Surgery With General Anesthesia | Phase 4 | Recruiting | University of California, San Francisco | 18000 | 2025-04-01 | 2026-05-26 |
| A Study to Evaluate the Accuracy of aTCI Model of Cipepofol in Patients With General Anesthesia During Elective Surgery Cipepofol - Anesthesia | Phase 4 | Recruiting | Haisco Pharmaceutical Group Co., Ltd. | 40 | 2025-01-06 | 2025-01-27 |
| Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures Dexmedetomidine and propofol, Midazolam and propofol, ketamine and propofol - Upper Gastrointestinal Endoscopy, Anesthesia | Phase 4 | Completed | Ain Shams University | 75 | 2024-12-12 | 2026-06-22 |
| Reduction of Remifentanil-related Complications Remifentanil (Limited) - Target Controlled Infusion system, Remifentanil (Control) - Target Controlled Infusion system - Anesthesia | Phase 4 | Not yet recruiting | Seoul National University Hospital | 160 | 2024-11-01 | 2023-12-01 |
Showing 20 of 215. Sign in to see all of them.
Pain, Postoperative (11) · Pain (9) · Agnosia (8) · Acute Pain (6) · Hypotension (6) · Obesity (4) · Acute Kidney Injury (3) · Obesity, Morbid (3) · Carcinoma, Non-Small-Cell Lung (2) · Depression (2) · Hemorrhage (2) · Hip Fractures (2) · Hyperalgesia (2) · Lung Neoplasms (2) · Neurocognitive Disorders (2)
Pathological Conditions, Signs and Symptoms (58) · Signs and Symptoms (49) · Neurologic Manifestations (38) · Pathologic Processes (22) · Nervous System Diseases (17) · Pain (16) · Postoperative Complications (15) · Neurobehavioral Manifestations (12) · Respiratory Tract Diseases (9) · Cardiovascular Diseases (8) · Perceptual Disorders (8) · Body Weight (7) · Nutrition Disorders (7) · Nutritional and Metabolic Diseases (7) · Overnutrition (7)
Propofol (48) · Dexmedetomidine (23) · Sevoflurane (22) · Remifentanil (14) · Ketamine (12) · Lidocaine (12) · Bupivacaine (11) · Sodium Chloride (11) · Midazolam (10) · Ropivacaine (9) · Fentanyl (8) · Rocuronium (7) · Saline Solution (7) · Norepinephrine (6) · Phenylephrine (6)
Ain Shams University (23) · Hopital Foch (11) · Guangzhou General Hospital of Guangzhou Military Command (6) · Inonu University (4) · Northwestern University (4) · University Hospital of Split (4) · Austin Health (3) · Seoul National University Hospital (3) · The University of Texas Health Science Center, Houston (3) · Universitas Indonesia (3) · University of California, San Diego (3) · Ajou University School of Medicine (2) · Brasilia University Hospital (2) · Ciusss de L'Est de l'Île de Montréal (2) · Mayo Clinic (2)
United States (48) · Egypt (27) · China (17) · France (14) · Turkey (Türkiye) (7) · Canada (6) · South Korea (6) · Croatia (5) · Belgium (4) · Brazil (4) · Italy (4) · Australia (3) · Finland (3) · Germany (3) · India (3)
Marc Fischler, MD (6) · Bozidar Duplancic (3) · Ruben Kovac (3) · Benjamin Benzon (2) · Goverdhan D Puri, MD, PhD (2) · Hrvoje Vucemilovic (2) · Ivan Velat (2) · Ivan Vukovic (2) · Ivo Juginovic (2) · Keira Mason, MD (2) · Matthew Borzage, PhD (2) · Morgan Le Guen, MD (2) · Philip J Peyton, MD FANZCA (2) · Svjetlana Dosenovic (2)
PMID 15905753, PMID 10320158, PMID 11812697, PMID 12505215, PMID 15155349, PMID 15321413, PMID 16443140, PMID 16480471, PMID 16774830, PMID 17377114, PMID 17667565, PMID 18173431, PMID 18813051, PMID 18931242, PMID 19447599, PMID 19672175, PMID 19815610, PMID 20011857, PMID 20418301, PMID 20455872, PMID 20650379, PMID 20835569, PMID 20975475, PMID 21156977, PMID 21307769, PMID 21334503, PMID 21334504, PMID 21785898, PMID 21889262, PMID 22108086, PMID 22255311, PMID 22297435, PMID 22326199, PMID 22417026, PMID 22813360, PMID 22822998, PMID 23092743, PMID 23126320, PMID 23135692, PMID 23135976, PMID 23262963, PMID 23399487, PMID 23460761, PMID 23530786, PMID 23969793, PMID 23997449, PMID 24034832, PMID 24486835, PMID 24920942, PMID 24946047
R01GM116119 (2), 2009 (1), 2015 (1), 2019 (1), 2025 (1), K25HL153954 (1), R01DK139484 (1)