6 recruiting, 5 completed, 5 unknown, 1 enrolling by invitation. 18 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 18 | Recruiting 6, Completed 5, Unknown 5, Enrolling by invitation 1, Withdrawn 1 |
Follow Ulcer: new trials by email Literature Review of Ulcer trials Research Report on Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Title: A Multicenter, Prospective, Modified Platform Trial Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers. Activate™ Matrix + SOC, AmnioDefend™ FT Matrix + SOC, Palisade™ DM Matrix + SOC - Skin Ulcer, Pressure Ulcer (PU) | Phase 4 | Recruiting | Sequence LifeScience, Inc. | 2000 | 2026-01-28 | 2026-06-24 |
| Use of PRP for the Healing of Grade III Ulcers PRP group, Classic treatment - PRP Injection, Ulcer | Phase 4 | Enrolling by invitation | Hospital Mutua de Terrassa | 50 | 2025-12-01 | 2025-12-12 |
| Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU - Diabetic Foot, DFU | Phase 4 | Recruiting | BioLab Holdings | 650 | 2025-07-15 | 2025-07-28 |
| Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy Activate™ Matrix, AmnioDefend™ FT Matrix, Palisade™ DM Matrix - Diabetic Foot Ulcer, DFU | Phase 4 | Recruiting | Sequence LifeScience, Inc. | 350 | 2025-07-11 | 2026-05-19 |
| Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers ACApatch™, caregraFT™, Standard of Care - Pressure Ulcer, Ulcer | Phase 4 | Recruiting | Tiger Biosciences, LLC. | 500 | 2025-05-20 | 2026-09-23 |
| Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg Ulcers Topical Wound Oxygen Therapy, Sham Control Topical Wound Oxygen - Venous Leg Ulcer (VLU) | Phase 4 | Recruiting | AOTI Ltd. | 212 | 2025-01-15 | 2025-11-19 |
| Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers. ACApatch™, caregraFT™, Standard of Care - Venous Leg Ulcer, Venous Leg | Phase 4 | Recruiting | Tiger Biosciences, LLC. | 340 | 2024-12-06 | 2026-09-22 |
| Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers Amnion-Intermediate-Chorion, Amnion-Chorion-Amnion, Standard of Care - Diabetic Foot Ulcer, Venous Leg Ulcer | Phase 4 | Completed | Cellution Biologics | 292 | 2024-10-14 | 2026-04-13 |
| Metoclopramide in Upper Gastrointestinal Bleed Metoclopramide 10mg, Saline - Upper GI Bleeding, Bleeds Gastric | Phase 4 | Unknown | Mercy Health System | 60 | 2023-05-20 | 2023-07-11 |
| The Association Between Interleukin-7 Receptor Gene Polymorphism and the Risk of Ulcerative Colitis Vedolizumab - Ulcerative Colitis (UC) | Phase 4 | Completed | Second Affiliated Hospital of Wenzhou Medical University | 898 | 2020-01-01 | 2026-02-10 |
| Study on Pressure Ulcers Prevention With Mepilex® Border Sacrum Dressing in Scheduled Cardiovascular Surgery Mepilex® Border dressing, Standard care - Pressure Ulcers, Prevention | Phase 4 | Unknown | University Hospital, Clermont-Ferrand | 478 | 2018-12-10 | 2019-01-31 |
| Wound Edge Changes Following Treatment With Santyl Collagenase Santyl Ointment, Placebo Comparator - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 10 | 2010-12-01 | 2013-05-30 |
| The Effect on an Ionic Silver Dressing in Head and Neck Patients With Malignant Fungating Wound silver-releasing dressings - Head and Neck Neoplasms, Head and Neck Cancer | Phase 4 | Unknown | National Taiwan University Hospital | 70 | 2009-01-01 | 2009-05-19 |
| H. Pylori Eradication on Healing of Iatrogenic Gastric Ulcer by Endoscopic Mucosal Resection Lansoprazole (proton pump inhibitor), amoxicillin, clarythromycin, Lansoprazole (proton pump inhibitor), placebo - Ulcer | Phase 4 | Unknown | Korean College of Helicobacter and Upper Gastrointestinal Research | 232 | 2008-09-01 | 2009-06-25 |
| A Randomized, Controlled Trial of Autologous Platelet Gel Treatment in Diabetic Foot Ulcers Autologous Platelet Gel - Diabetic Foot Ulcer | Phase 4 | Withdrawn | Unity Health Toronto | 2008-03-01 | 2023-08-28 | |
| Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers Naproxen, Aspirin, Celecoxib - Gastroduodenal Ulcer | Phase 4 | Completed | Research Associates of New York, LLP | 125 | 2007-10-01 | 2008-10-23 |
| Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care Unit esomeprazole 40 mg, famotidine 20 mg - Ulcer | Phase 4 | Completed | Far Eastern Memorial Hospital | 60 | 2007-09-01 | 2013-10-16 |
| Study of Long-Term Use of Proton-Pump-Inhibitors in General Practice esomeprazole - Dyspepsia, Gastroesophageal Refluxdisease | Phase 4 | Unknown | Glostrup University Hospital, Copenhagen | 150 | 2006-08-01 | 2006-08-15 |
Diabetic Foot (6) · Varicose Ulcer (4) · Wounds and Injuries (4) · Foot Ulcer (3) · Pressure Ulcer (3) · Leg Ulcer (2) · Skin Ulcer (2) · Colitis (1) · Colitis, Ulcerative (1) · Dyspepsia (1) · Gastroesophageal Reflux (1) · Gastrointestinal Hemorrhage (1) · Head and Neck Neoplasms (1) · Hemorrhage (1)
Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Skin Diseases (10) · Skin and Connective Tissue Diseases (10) · Skin Ulcer (8) · Cardiovascular Diseases (7) · Vascular Diseases (7) · Diabetes Complications (6) · Diabetes Mellitus (6) · Diabetic Angiopathies (6) · Diabetic Neuropathies (6) · Endocrine System Diseases (6) · Leg Ulcer (5) · Digestive System Diseases (4) · Gastrointestinal Diseases (4)
Standard of Care (4) · Esomeprazole (2) · Amoxicillin (1) · Aspirin (1) · Celecoxib (1) · Clopidogrel (1) · Famotidine (1) · Lansoprazole (1) · Metoclopramide (1) · Naproxen (1) · Proton Pump Inhibitors (1) · Sodium Chloride (1) · Sugars (1) · cancer procoagulant (1) · vedolizumab (1)
Sequence LifeScience, Inc. (2) · Tiger Biosciences, LLC. (2) · AOTI Ltd. (1) · BioLab Holdings (1) · Cellution Biologics (1) · Far Eastern Memorial Hospital (1) · Glostrup University Hospital, Copenhagen (1) · Healthpoint (1) · Hospital Mutua de Terrassa (1) · Korean College of Helicobacter and Upper Gastrointestinal Research (1) · Mercy Health System (1) · National Taiwan University Hospital (1) · Research Associates of New York, LLP (1) · Second Affiliated Hospital of Wenzhou Medical University (1) · Unity Health Toronto (1)
United States (10) · Taiwan (2) · Canada (1) · China (1) · Denmark (1) · France (1) · South Korea (1) · Spain (1)
Thomas Serena, MD (2) · Anil Hingorani, MD (1) · Art J Tallis, DPM (1) · Herbert B Slade, MD (1) · Hyun Chae Jung (1) · James Aisenberg, MD (1) · James L Mahoney, MD, FRCSC (1) · Mike Griffiths, DProf, DMS, CRT, FCMI (1) · Peter Bytzer, ass. professor, ph.d (1) · Timothy R Daniels, MD, FRCSC (1) · Tzong-Hsi Lee, M.D. (1) · Wael Tawfick, MB.BCH, MRCSI. (1) · We-Yu Hu (1)