153 completed, 47 unknown, 23 recruiting, 13 terminated. 92 Not applicable, 42 Phase 3, 42 Phase 4, 29 Phase 2, 14 Phase 1.
Follow Dyspepsia: new trials by email Literature Review of Dyspepsia trials Research Report on Dyspepsia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NLR and PLR in H. Pylori-Associated Gastritis Helicobacter Pylori Infection, Gastritis | Not yet recruiting | Assiut University | 90 | 2026-09-01 | 2026-09-09 | |
| Pylori Duo for Adjunctive Treatment and Prevention of Recurrence of Helicobacter Pylori Infection Omeprazole, Pylera (Bismuth subcitrate potassium, metronidazole, tetracycline) given in combination with omeprazole, Pylori Duo - Helicobacter Pylori Infection, Dyspepsia | Not applicable | Not yet recruiting | Gala Servicios Clinicos S.L. | 140 | 2026-08-31 | 2026-07-27 |
| Virtual Poetry Workshops to Enhance Patient Well Being and Reduce Anxiety Poetry, Poetry Manual - Dyspepsia, Gastroparesis | Not applicable | Recruiting | Ohio State University | 80 | 2026-07-17 | 2026-07-21 |
| A Clinical Trial to Evaluate the Effects of a Fibre Supplement on Microbiome and Gut Health Essential Fibre+ - Gut Health, Microbiome | Not applicable | Active not recruiting | Artah Nutrition Limited | 50 | 2026-06-01 | 2026-08-24 |
| Effect of Digestive Enzymes as Add on Therapy on Patients With Functional Dyspepsia. Digestive enzyme 325mg, PPI 20 mg + Domperidone 10 mg - Dyspepsia, Functioanl Dyspepsia | Phase 4 | Not yet recruiting | Rakibul Mostafa | 120 | 2026-05-15 | 2026-05-11 |
| Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication vonoprazan-based triple therapy (VAL regimen), Esomeprazole-based triple therapy (EAL regimen) - Helicobacter Pylori Infection, Dyspepsia | Phase 4 | Recruiting | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 80 | 2026-04-15 | 2026-04-22 |
| Predicting Peptic Complications Using H. Pylori Serology and Gastric Ultrasound Peptic Ulcer Disease, HELICOBACTER PYLORI INFECTIONS | Not yet recruiting | Assiut University | 230 | 2026-04-01 | 2026-03-09 | |
| Symptoms and Quality of Life in Patients With Heterotopic Gastric Mucosa (HGM) Heterotopic Gastric Mucosa of the Proximal Esophagus, Gastric Inlet Patches | Recruiting | Knappschaft Kliniken GmbH | 721 | 2026-03-24 | 2026-04-14 | |
| Holy Basil in The Treatment of Dyspepsia Holy basil extract - Dyspepsia and Other Specified Disorders of Function of Stomach | Phase 2 / Phase 3 | Recruiting | Mahidol University | 27 | 2026-02-13 | 2026-03-24 |
| Effect of H. Pylori Eradication on The Improvement of Gastrointestinal Symptoms Helicobacter Pylori Infection, Dyspepsia | Not yet recruiting | Amany Usama Ahmed Arafa | 100 | 2025-12-20 | 2025-12-16 | |
| Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment Bismuth, Esomeprazole, Tetracycline - Gastritis, Dyspepsia | Phase 4 | Recruiting | Yongquan Shi | 1248 | 2025-10-28 | 2025-12-02 |
| Exocrine Pancreatic Insufficiency and Functional Dyspepsia fecal elastase, Serum cytokines - Exocrine Pancreatic Insufficiency, Dyspepsia | Not yet recruiting | Maria Marta Piskorz | 65 | 2025-09-01 | 2025-08-08 | |
| A Clinical Study to Assess the Effectiveness of ENO Lime in Participants With Ajeerna Vyadhi (Acidity, Acid Indigestion, Indigestion, and Associated Nausea) ENO Lime - Indigestion Acid, Indigestion | Phase 3 | Completed | HALEON | 40 | 2025-08-20 | 2025-09-17 |
| Visible Abdominal Distension Biofeedback, Placebo - Irritable Bowel Syndrome, Dyspepsia | Not applicable | Recruiting | Hospital Universitari Vall d'Hebron Research Institute | 100 | 2025-07-30 | 2025-10-31 |
| High Resolution Gastric Mapping and Gastroduodenal Manometry Alimetry, tVNS, Gastroduodenal Manometry - Dyspepsia | Not applicable | Recruiting | Mayo Clinic | 100 | 2025-07-11 | 2026-09-11 |
| A Study of Chios Mastic Water in Dyspepsia Chios mastic beverage, Placebo beverage - Dyspepsia | Not applicable | Recruiting | Harokopio University | 60 | 2025-07-10 | 2025-09-15 |
| Effect of Triple Versus Quadruple Therapy for Treating Helicobacter Pylori Infection Triple drug regimen, Quadruple therapy - Dyspepsia | Not applicable | Enrolling by invitation | Akil Al Islam | 66 | 2025-07-01 | 2026-05-07 |
| Effect of Amitriptyline and Trifluoperazine on Patients With Functional Dyspepsia Tablet Amitriptyline 10 milligrams, Tablet Trifluoperazine 1 milligrams twice daily, Standard First-Line Therapy - Functional Dyspepsia | Phase 2 / Phase 3 | Recruiting | Md. Moktadirul Hoque Shuvo | 120 | 2025-07-01 | 2026-05-07 |
| The Difference in Carbon Footprint Between Diagnostic Upper GI Endoscopy in Dyspeptic Patients Versus Therapeutic Upper GI Bleeding Carbon Footprint in Upper GI Endoscopy, Dyspepsia | Recruiting | King Chulalongkorn Memorial Hospital | 75 | 2025-06-01 | 2025-12-03 | |
| A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms Danning Tablet - Indigestion, Dyspepsia | Recruiting | Shanghai Hutchison Pharmaceuticals Limited | 4500 | 2025-04-30 | 2025-05-14 |
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Gastroesophageal Reflux (37) · Gastrointestinal Diseases (21) · Heartburn (19) · Peptic Ulcer (19) · Abdominal Pain (18) · Gastritis (14) · Gastroparesis (14) · Irritable Bowel Syndrome (13) · Constipation (11) · Nausea (11) · Depression (7) · Vomiting (7) · Diarrhea (6) · Anxiety Disorders (5)
Pathological Conditions, Signs and Symptoms (256) · Signs and Symptoms (256) · Signs and Symptoms, Digestive (252) · Digestive System Diseases (104) · Gastrointestinal Diseases (83) · Stomach Diseases (43) · Esophageal Diseases (39) · Esophageal Motility Disorders (37) · Neurologic Manifestations (37) · Deglutition Disorders (36) · Intestinal Diseases (35) · Duodenal Diseases (20) · Gastroenteritis (19) · Pain (19) · Pathologic Processes (15)
Esomeprazole (22) · Amoxicillin (13) · Clarithromycin (11) · Omeprazole (11) · Bismuth (9) · tegaserod (7) · Domperidone (5) · Pantoprazole (5) · itopride (5) · Biofeedback, Psychology (4) · Endoscopy (4) · Ranitidine (4) · Tetracycline (4) · Z 338 (4) · Berberine (3)
Mayo Clinic (9) · Chinese University of Hong Kong (7) · Hospital Universitari Vall d'Hebron Research Institute (7) · Novartis (7) · Universitaire Ziekenhuizen KU Leuven (7) · Xijing Hospital of Digestive Diseases (7) · Children's Mercy Hospital Kansas City (5) · Forest Laboratories (5) · Radboud University Medical Center (5) · Air Force Military Medical University, China (4) · AstraZeneca (3) · Maastricht University Medical Center (3) · RenJi Hospital (3) · Sheffield Teaching Hospitals NHS Foundation Trust (3) · Asan Medical Center (2)
United States (63) · China (35) · Spain (12) · Belgium (11) · Canada (10) · Netherlands (9) · United Kingdom (9) · Brazil (8) · South Korea (8) · Sweden (8) · France (7) · Germany (6) · Italy (6) · Thailand (6) · Turkey (Türkiye) (6)
Yongquan Shi, Ph. D (4) · Fernando Azpiroz, MD (3) · Jan Tack, MD (3) · Craig A. Friesen, MD (2) · Gisela Chelimsky, MD (2) · Justin C.Y. Wu, MBChB(CUHK) (2) · Labros Sidossis, PhD (2) · Nicholas Talley, MD (2) · Ying An, Ph.D (2) · Adil Bharucha, MBBS, MD (1) · Adil E Bharucha, MBBS, M.D. (1) · Adil E Bharucha, MD (1)
PMID 28705783, PMID 34862940, PMID 39989849, PMID 10562588, PMID 12135027, PMID 14531531, PMID 15234753, PMID 15529838, PMID 16678560, PMID 16688361, PMID 17697200, PMID 17697201, PMID 17998836, PMID 18070232, PMID 18267026, PMID 18561877, PMID 18616658, PMID 19014552, PMID 19140233, PMID 19150702, PMID 19337637, PMID 19432972, PMID 19577008, PMID 19857610, PMID 20216101, PMID 20541625, PMID 20925534, PMID 21848799, PMID 22228948, PMID 22343090, PMID 22463973, PMID 22619884, PMID 23052498, PMID 23171089, PMID 23379680, PMID 23912367, PMID 23957383, PMID 24314790, PMID 24381643, PMID 24440931, PMID 24647139, PMID 24674944, PMID 24886078, PMID 24950724, PMID 24955450, PMID 25587615, PMID 25721705, PMID 25761431, PMID 25879863, PMID 25914475
P01DK068055 (3), R01DK122280 (2), 2015 (1), K23DK131334 (1), R01DK115950 (1), U01DK065713 (1), UL1RR024150 (1), UL1TR002377 (1)