Skin Ulcer: Clinical Trials

977 completed, 337 unknown, 188 recruiting, 176 terminated. 1074 Not applicable, 232 Phase 2, 133 Phase 1, 124 Phase 3, 106 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	1074	Completed 542, Unknown 180, Recruiting 113, Terminated 89, Not yet recruiting 70, Withdrawn 35, Active not recruiting 28, Enrolling by invitation 13, Suspended 4
Phase 2	232	Completed 125, Unknown 38, Terminated 26, Recruiting 15, Not yet recruiting 12, Withdrawn 9, Active not recruiting 6, Suspended 1
Phase 1	133	Completed 66, Unknown 31, Terminated 12, Not yet recruiting 8, Recruiting 6, Active not recruiting 5, Withdrawn 3, Enrolling by invitation 1, Suspended 1
Phase 3	124	Completed 61, Terminated 29, Unknown 13, Recruiting 10, Withdrawn 5, Active not recruiting 3, Not yet recruiting 3
Phase 4	106	Completed 46, Recruiting 16, Terminated 16, Unknown 16, Withdrawn 8, Not yet recruiting 2, Active not recruiting 1, Enrolling by invitation 1
Early Phase 1	20	Completed 7, Unknown 7, Not yet recruiting 2, Withdrawn 2, Recruiting 1, Terminated 1

Follow Skin Ulcer: new trials by email Literature Review of Skin Ulcer trials Research Report on Skin Ulcer

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
On the Move: Center and Home-Based Exercise to Enhance Mobility in Diabetic Foot Ulcer Recovery 12-week exercise regimen, 12-week standard of care - Diabetic Foot Ulcer	Not applicable	Not yet recruiting	University of Maryland, Baltimore	60	2027-06-01	2026-10-07
Simplified Acute Physiology Score 2 and Pressure Ulcer Prediction in ICU. Pressure ulcer - Pressure Ulcers		Not yet recruiting	University Hospital, Bordeaux	500	2027-02-01	2026-09-09
Clinical Performance of ComBatic™ Antimicrobial Wound Care Products in Hard-to-Heal Wounds Irrigation Solution for wounds, Hydrogel for wound care - Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer), Chronic Wound Care	Phase 2	Not yet recruiting	University of Calgary	96	2027-01-01	2026-10-14
Subcutaneous Dexpanthenol Administration and Wound Epithelialization Dexpanthenol, Standard Wound Care - Chronic Wounds, Diabetic Foot Ulcer	Not applicable	Not yet recruiting	Dilara CANBAY OZDEMIR	40	2026-12-02	2026-10-22
Clinical Efficacy of Modified Simiao Yongan Decoction and Endovascular Therapy for Diabetic Foot Ulcers Modified Simiao Yongan Decoction, Endovascular Therapy and Standard Care - Diabetic Foot Ulcer, Damp-Heat Toxins Accumulation Syndrome	Not applicable	Not yet recruiting	Chengdu University of Traditional Chinese Medicine	120	2026-12-01	2026-09-08
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Skin Ulcer cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells - Skin Ulcer	Phase 1	Not yet recruiting	The Foundation for Orthopaedics and Regenerative Medicine	20	2026-12-01	2026-10-20
18F-FDG PET/CT for Diagnosis of Diabetic Foot Osteomyelitis 18F-FDG PET/CT - Diabetic Foot Infections		Not yet recruiting	Jewish General Hospital	150	2026-11-01	2026-09-18
Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis	Phase 4	Not yet recruiting	Jay C. Buckey Jr.	100	2026-11-01	2026-09-09
Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units ALLEVYN◊ COMPLETE CARE Sacrum - Pressure Ulcers (Hospital-acquired Pressure Injuries)	Not applicable	Not yet recruiting	Smith & Nephew, Inc.	330	2026-10-30	2026-09-30
The Effect Of Low-Fidelity Simulation Education Pressure Injuries Simulation-Based Training, Traditional Training - Nursing Education Research, Simulation Based Learning	Not applicable	Not yet recruiting	Hilal Türkben Polat	88	2026-10-26	2026-10-22
Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle Surgery Diabetic Foot Ulcer, Wound Healing		Recruiting	Universidade Sao Francisco	40	2026-10-21	2026-10-22
Seltoplasmid Plus Revascularization for Diabetic Infrapopliteal Chronic Limb-Threatening Ischemia Lower-Extremity Revascularization, Donaperminogene Seltoplasmid - Chronic Limb-Threatening Ischemia, Diabetic Foot Ulcer	Phase 4	Not yet recruiting	First Affiliated Hospital of Wenzhou Medical University	180	2026-10-20	2026-09-18
a Prospective, Multicenter, Randomized Controlled Trial, With a Non-randomized Sentinel Cohort, Evaluating the Efficacy of Bioxheal, a Single-layer Placental-derived Biologic in Nonhealing Diabetic Foot Ulcers Standard of Care, BIOxHEAL (human amniotic membrane allograft) - Diabetic Foot Ulcer, Amniotic Membrane Placental Allograft	Phase 3	Recruiting	Applied Biologics, LLC	253	2026-10-08	2026-10-16
The GORE® VIABAHN® FORTEGRA Venous Stent Post-Approval Study GORE® VIABAHN® FORTEGRA Venous Stent - Venous Thromboses, Venous Disease	Not applicable	Not yet recruiting	W.L.Gore & Associates	150	2026-10-07	2026-08-12
The Effect of Pressure Ulcer Prevention Training Delivered to Nursing Students Using the Pecha Kucha Technique Pecha Kucha Presentation, PowerPoint Presentation - Students, Nursing	Not applicable	Not yet recruiting	Zonguldak Bulent Ecevit University	90	2026-10-05	2026-09-01
LUT017 Gel for Venous Leg Ulcers and Chronic Non-Healing Skin Wounds in Adults LUT017 gel - Venous Leg Ulcer, Chronic Non-Healing Cutaneous Wounds	Phase 1	Not yet recruiting	Antoni Ribas	18	2026-10-02	2026-05-29
Activity Reduction vs Advice for Plantar Hotspots in Diabetes Individualized Objectively Monitored Activity Reduction, Standard Activity-Reduction Advice - Diabetic Foot, Diabetic Peripheral Neuropathy	Not applicable	Not yet recruiting	Shifa International Hospital	100	2026-10-01	2026-09-25
Placental Cells for Diabetic Foot Ulcers Placenta Stem Cells - Diabetic Foot Ulcer	Phase 1	Not yet recruiting	Wake Forest University Health Sciences	12	2026-10-01	2026-07-07
Dose-Response Structured Calf Muscle Pump Activation Strategies Versus Unsupervised Home Walks Dose-Response Structured CMP Activation, Active Control - Venous Ulcer of Leg	Not applicable	Not yet recruiting	MTI University	80	2026-10-01	2026-08-13
Evaluation of the Effectiveness of Vision Care in Preventing Falls in Hospitalized Patients Vision Care - Falls, Ulcer, Pressure	Not applicable	Not yet recruiting	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	530	2026-10-01	2026-10-22

Showing 20 of 1953. Sign in to see all of them.

Narrower conditions

Diabetic Foot (1030)  ·  Pressure Ulcer (522)  ·  Varicose Ulcer (366)  ·  Diabetes Mellitus (247)  ·  Foot Ulcer (171)  ·  Leg Ulcer (141)  ·  Wounds and Injuries (111)  ·  Ulcer (110)  ·  Diabetic Neuropathies (50)  ·  Diabetes Complications (49)  ·  Diabetes Mellitus, Type 2 (49)  ·  Pyoderma Gangrenosum (36)  ·  Peripheral Arterial Disease (34)  ·  Spinal Cord Injuries (32)

Broader conditions

Skin and Connective Tissue Diseases (1952)  ·  Skin Diseases (1942)  ·  Cardiovascular Diseases (1337)  ·  Vascular Diseases (1334)  ·  Leg Ulcer (1296)  ·  Endocrine System Diseases (1065)  ·  Diabetic Angiopathies (1019)  ·  Diabetes Complications (982)  ·  Diabetic Neuropathies (981)  ·  Foot Ulcer (920)  ·  Diabetes Mellitus (822)  ·  Varicose Veins (351)  ·  Nutritional and Metabolic Diseases (304)  ·  Metabolic Diseases (288)

Interventions

Standard of Care (124)  ·  Bandages (25)  ·  Control Groups (19)  ·  Negative-Pressure Wound Therapy (15)  ·  Sodium Chloride (15)  ·  Educational Status (14)  ·  Low-Level Light Therapy (11)  ·  Collagenases (10)  ·  Debridement (10)  ·  Therapeutics (9)  ·  Saline Solution (8)  ·  Gels (7)  ·  Hydrogels (7)  ·  Hyperbaric Oxygenation (7)  ·  Becaplermin (6)

Sponsors

Healthpoint (19)  ·  Integra LifeSciences Corporation (19)  ·  ConvaTec Inc. (18)  ·  University of Texas Southwestern Medical Center (17)  ·  Molnlycke Health Care AB (16)  ·  Organogenesis (15)  ·  Cairo University (14)  ·  Centre Hospitalier Universitaire de Nīmes (14)  ·  Smith & Nephew, Inc. (14)  ·  US Department of Veterans Affairs (14)  ·  Universidad Complutense de Madrid (14)  ·  MiMedx Group, Inc. (13)  ·  Laboratoires URGO (12)  ·  Anterogen Co., Ltd. (10)  ·  University Ghent (10)

Countries

United States (642)  ·  France (134)  ·  Turkey (Türkiye) (130)  ·  United Kingdom (115)  ·  Canada (76)  ·  Germany (74)  ·  Spain (71)  ·  China (67)  ·  Italy (67)  ·  Egypt (46)  ·  Sweden (43)  ·  Taiwan (43)  ·  Poland (39)  ·  Denmark (38)  ·  Israel (31)

Top investigators

Herbert B Slade, MD (15)  ·  William Marston, MD (8)  ·  David Armstrong, DPM, MD, PhD (7)  ·  Angelina Ferguson, DNP (6)  ·  Thomas Serena, MD (6)  ·  Lawrence Lavery, DPM MPH (5)  ·  Prema Dhanraj, MS, MCh (5)  ·  Chandan K Sen, PhD (4)  ·  Lawrence Lavery, DPM (4)  ·  Robert Galiano, MD (4)  ·  Robert Kirsner, MD (4)  ·  Thomas E Serena, MD (4)  ·  Tommy Lee, MSHS (4)  ·  Windy Cole, DPM (4)

Results publications

PMID 28614678, PMID 16291066, PMID 23958264, PMID 24767584, PMID 26738255, PMID 27269974, PMID 29037354, PMID 34187716, PMID 35534614, PMID 10693087, PMID 10720604, PMID 11319655, PMID 11926784, PMID 12589096, PMID 15353531, PMID 15793206, PMID 16291063, PMID 16389125, PMID 16758177, PMID 17277315, PMID 18612117, PMID 18990064, PMID 19383872, PMID 20032779, PMID 20332511, PMID 20336198, PMID 20655123, PMID 20818193, PMID 20876709, PMID 21540423, PMID 21636159, PMID 22417277, PMID 22883509, PMID 23159553, PMID 23222938, PMID 23613782, PMID 24657294, PMID 24822048, PMID 24843743, PMID 25329391, PMID 25493265, PMID 25538310, PMID 25580754, PMID 25705296, PMID 25765355, PMID 25787803, PMID 25860638, PMID 25897193, PMID 26025146, PMID 26340966

NIH funding

2015 (4), 2023 (4), U24DK122927 (3), 2014 (2), 2018 (2), 2019 (2), K23DK131261 (2), R01HD041490 (2), 2008 (1), 2016 (1), 2017 (1), I01HX003704 (1), K23DK081021 (1), K23HL143178 (1), N01AR092238 (1)