Gastrointestinal Hemorrhage: Clinical Trials

202 completed, 76 unknown, 38 recruiting, 28 not yet recruiting. 132 Not applicable, 55 Phase 4, 46 Phase 3, 30 Phase 2, 4 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	132	Completed 64, Unknown 28, Recruiting 15, Terminated 10, Withdrawn 7, Not yet recruiting 4, Active not recruiting 2, Enrolling by invitation 1, Suspended 1
Phase 4	55	Completed 32, Unknown 10, Not yet recruiting 5, Recruiting 3, Withdrawn 3, Terminated 2
Phase 3	46	Completed 26, Unknown 7, Terminated 5, Recruiting 4, Not yet recruiting 3, Withdrawn 1
Phase 2	30	Completed 15, Recruiting 4, Unknown 4, Terminated 3, Not yet recruiting 2, Withdrawn 2
Phase 1	4	Completed 2, Terminated 2
Early Phase 1	3	Completed 1, Not yet recruiting 1, Unknown 1

Follow Gastrointestinal Hemorrhage: new trials by email Literature Review of Gastrointestinal Hemorrhage trials Research Report on Gastrointestinal Hemorrhage

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
FENOX Trial (Comparative Effectiveness of Fexuprazan Co-therapy in Patients Receiving Non-Vitamin K Antagonist Oral Anticoagulants) Fexuprazan, NOAC therapy - Atrial Fibrillation (AF), Upper Gastrointestinal Bleeding (UGIB)	Not applicable	Not yet recruiting	Ewha Womans University Mokdong Hospital	1000	2026-12-01	2026-03-27
Detection of Blood in the GI Lumen With HemoPill Acute HemoPill acute - Upper GI Bleeding	Not applicable	Recruiting	Stony Brook University	50	2026-10-01	2026-10-09
HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding Embolization therapy - Hemorrhage, Gastrointestinal Hemorrhage		Not yet recruiting	Aesculap AG	176	2026-09-30	2026-08-07
A Study of Chlorophyllin or Placebo With Standard Treatment for Late Radiation Induced Luminal Gastrointestinal Tract Bleeding Chlorophyllin, Sodium Copper Complex, Placebo - Radiation Proctitis, Gastrointestinal Hemorrhage	Phase 3	Not yet recruiting	Tata Memorial Centre	200	2026-09-15	2026-09-23
Gastrointestinal Bleeding in Critically Ill Patients Gastrointestinal Hemorrhage, Critical Illness		Not yet recruiting	Assiut University	310	2026-09-05	2026-09-16
Trimebutine Maleate for Enhancing Gastric Visualization in Acute Upper Gastrointestinal Bleeding Trimebutine Maleate, Placebo - Acute Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding	Phase 2 / Phase 3	Not yet recruiting	Assiut University	100	2026-09-01	2026-08-06
Potassium-competitive Acid Blocker Versus Double Dose Proton Pump Inhibitors in High High-risk Peptic Ulcer Bleeding Vonoprazon, Esomeprazole - Bleeding	Not applicable	Not yet recruiting	National Cheng-Kung University Hospital	108	2026-09-01	2026-08-20
Tegoprazan Versus Lansoprazole for Endoscopic Ulcer Healing in Bleeding Peptic Ulcers Tegoprazan tablet, Lansoprazole capsules - Peptic Ulcer Bleeding	Phase 2	Recruiting	Universitas Indonesia	162	2026-08-06	2026-08-21
A Disposable Endoscopic Closing Device Used for the Closure of Gastrointestinal Tissue disposable endoscopic closing device, metal clips, or metal clips in combination with nylon loops - Gastrointestinal Bleeding, Gastrointestinal Neoplasms	Not applicable	Not yet recruiting	Jiangsu Vedkang Medical Science and Technology Co., Ltd	60	2026-07-31	2026-07-27
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils Concerto Versa™ Detachable Coils - Arteriovenous Malformation, Gastrointestinal Bleed		Enrolling by invitation	Medtronic Endovascular	30	2026-07-24	2026-10-15
Routine Use of Potassium Competitive Acid Blocker vs. Guideline-Directed Gastrointestinal Protection Strategy in Acute Myocardial Infarction Zastaprazan, Proton Pump Inhibitors (PPI) - Acute Myocardial Infarction (AMI), Gastrointestinal Bleeding	Phase 3	Recruiting	Samsung Medical Center	5000	2026-06-23	2026-06-26
A Study of a Urine Test to Detect Colorectal Cancer 3-metabolite biosensor - Colorectal Cancer, Precancerous Polyp		Recruiting	Memorial Sloan Kettering Cancer Center	210	2026-06-11	2026-06-15
Acute Kidney Injury in Upper GI Bleeding Patients Observational assessment - Upper Gastrointestinal Bleeding, Acute Kidney Injury		Not yet recruiting	Sohag University	200	2026-05-15	2026-06-09
Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing Esomeprazole (Intravenous), Esomeprazole (Oral), Sucralfate Suspension - Early Gastric Cancer, Gastric Dysplasia	Phase 4	Not yet recruiting	LanZhou University	120	2026-04-20	2026-03-23
Capsule Endoscopy in GI Bleeding: A Retrospective Study capsule endoscopy - Gastrointestinal Bleeding		Not yet recruiting	Changhai Hospital	350	2026-03-15	2026-03-19
Algorithm-based Management to Reduce the Recurrence of GI Bleeding and Severe Epistaxis in Von Willebrand Disease Optimized management, Standard of care management - Von Willebrand Disease (VWD)	Not applicable	Recruiting	University Hospital, Lille	66	2026-03-10	2026-05-18
The Auxiliary Effect of Artificial Intelligence in the Detection of Precancerous Lesions in Proximal Colon Cancer AI group, Serial group, Standard colonoscopy group - Abdominal Pain, Black Stools		Not yet recruiting	Limian Er	1200	2026-02-26	2026-01-14
Effect of Ondansetron on Patient Tolerance, Efficacy and Endoscopist Workload in Unsedated Endoscopy for Upper Gastrointestinal Bleeding intravenous ondansetron, Placebo - Esophagogastroduodenoscopy, Upper Gastrointestinal Bleeding (UGIB)	Phase 4	Completed	Peking Union Medical College Hospital	80	2026-02-16	2026-09-16
How Often Does the Fecal Test for Occult Blood Turn Positive After Using Blood Thinners? Fecal Immunochemical Test (FIT) - Gastrointestinal Bleeding, Antiplatelet Agents		Not yet recruiting	Jordan Collaborating Cardiology Group	200	2026-02-01	2026-01-08
Comparison of Risk Scores in Upper Gastrointestinal Bleeding UGI Bleed		Completed	Kathmandu Medical College and Teaching Hospital	100	2026-02-01	2026-09-15

Showing 20 of 392. Sign in to see all of them.

Narrower conditions

Peptic Ulcer Hemorrhage (55)  ·  Hemorrhage (30)  ·  Peptic Ulcer (22)  ·  Fibrosis (16)  ·  Melena (15)  ·  Esophageal and Gastric Varices (13)  ·  Hematemesis (12)  ·  Liver Cirrhosis (12)  ·  Hypertension, Portal (11)  ·  Atrial Fibrillation (10)  ·  Emergencies (10)  ·  Acute Coronary Syndrome (9)  ·  Ulcer (9)  ·  Anemia (8)

Broader conditions

Pathologic Processes (392)  ·  Pathological Conditions, Signs and Symptoms (392)  ·  Digestive System Diseases (389)  ·  Gastrointestinal Diseases (384)  ·  Hemorrhage (362)  ·  Cardiovascular Diseases (52)  ·  Intestinal Diseases (52)  ·  Vascular Diseases (45)  ·  Liver Diseases (32)  ·  Signs and Symptoms (32)  ·  Stomach Diseases (30)  ·  Duodenal Diseases (28)  ·  Heart Diseases (28)  ·  Hemic and Lymphatic Diseases (27)

Interventions

Esomeprazole (16)  ·  Omeprazole (14)  ·  Pantoprazole (13)  ·  Endoscopy (12)  ·  Standard of Care (7)  ·  Argon Plasma Coagulation (6)  ·  Gastroscopy (6)  ·  Capsule Endoscopy (5)  ·  Colonoscopy (5)  ·  Endoscopy, Digestive System (5)  ·  Injections (5)  ·  Lansoprazole (5)  ·  Metoclopramide (5)  ·  Proton Pump Inhibitors (5)  ·  Rabeprazole (5)

Sponsors

Chinese University of Hong Kong (25)  ·  Assiut University (13)  ·  AstraZeneca (8)  ·  National Cheng-Kung University Hospital (6)  ·  Odense University Hospital (6)  ·  Changhai Hospital (5)  ·  Bayer (4)  ·  Mahidol University (4)  ·  McMaster University (4)  ·  Medtronic - MITG (4)  ·  University of Southern California (4)  ·  Washington University School of Medicine (4)  ·  AdventHealth (3)  ·  Assistance Publique - Hôpitaux de Paris (3)  ·  Beijing 302 Hospital (3)

Countries

United States (74)  ·  China (52)  ·  France (21)  ·  Taiwan (19)  ·  Canada (18)  ·  South Korea (18)  ·  Spain (16)  ·  Germany (15)  ·  United Kingdom (14)  ·  Turkey (Türkiye) (13)  ·  Italy (12)  ·  Denmark (11)  ·  Hong Kong (11)  ·  Egypt (10)  ·  Thailand (10)

Top investigators

Loren Laine, M.D. (4)  ·  Bor-Shyang Sheu, MD (3)  ·  Francis KL Chan, MD (3)  ·  Arnulf Ferlitsch, MD (2)  ·  Deborah Cook, MD (2)  ·  Francisco M Tercero, MD (2)  ·  Hwai-jeng Lin, M.D. (2)  ·  Kelvin D Higa, MD (2)  ·  Loren Laine, MD (2)  ·  Rapat Pittayanon, MD (2)  ·  Robin Hofmann, MD, PhD (2)  ·  Saeed S Hamid, FRCP, FACG (2)

Results publications

PMID 21490373, PMID 26417980, PMID 29803838, PMID 31634917, PMID 24658598, PMID 29526139, PMID 29802172, PMID 31222633, PMID 32563378, PMID 32828873, PMID 37644556, PMID 42674788, PMID 10406244, PMID 10452677, PMID 10811322, PMID 11281437, PMID 11604980, PMID 12378346, PMID 14623622, PMID 14745388, PMID 15128344, PMID 15492601, PMID 1556428, PMID 15840076, PMID 16240216, PMID 16494583, PMID 16925605, PMID 17101296, PMID 17382282, PMID 17435073, PMID 17608775, PMID 17899453, PMID 18205663, PMID 18205666, PMID 18300349, PMID 18423628, PMID 18684171, PMID 18753649, PMID 19086953, PMID 19104934, PMID 19205735, PMID 19221370, PMID 20029415, PMID 20138043, PMID 20151726, PMID 20336314, PMID 20427808, PMID 20492042, PMID 20492047, PMID 20562722

NIH funding

K23DK118179 (2), 2009 (1), 2015 (1), 2016 (1), K23DK125718 (1), U10CA180888 (1)