25 completed, 5 terminated, 5 withdrawn, 1 unknown. 11 Phase 4, 8 Phase 2, 6 Phase 1, 3 Phase 3, 2 Early Phase 1.
Follow Healthpoint: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2 Exploratory Pharmacodynamic Study of HP802-247 in Venous Leg Ulcers HP802-247 - Venous Leg Ulcers | Phase 2 | Terminated | Healthpoint | 1 | 2014-07-01 | 2016-10-03 |
| Observational Study Providing 12 Months of Safety Follow-Up From First Exposure to HP802-247 No treatment specified, No treatment - Venous Leg Ulcer (VLU) | Completed | Healthpoint | 221 | 2014-05-01 | 2017-06-22 | |
| Santyl Applications to Diabetic Foot Ulcers Collagenase SANTYL® Ointment, Hydrogel (if needed) and foam dressing - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 215 | 2014-04-01 | 2016-02-17 |
| Safety and Efficacy Trial of HP802-247 in the Treatment of Chronic Venous Leg Ulcers HP802-247, HP802-247 Vehicle - Venous Ulcer, Venous Stasis Ulcer | Phase 3 | Terminated | Healthpoint | 252 | 2013-11-01 | 2016-10-03 |
| Study of Oasis Ultra in Diabetic Foot Ulcers Oasis, Standard - Diabetic Foot Ulcer | Phase 4 | Completed | Healthpoint | 82 | 2013-05-01 | 2015-01-22 |
| Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2 HP802-247, Vehicle - Venous Leg Ulcers | Phase 3 | Completed | Healthpoint | 155 | 2012-11-01 | 2017-07-26 |
| Long Term Follow Up to Determine the Effects of Collagenase SANTYL Ointment on Scar Formation Santyl - Follow up to Acute Wound Scar Study | Completed | Healthpoint | 12 | 2012-09-01 | 2013-04-15 | |
| Safety Study Providing 12 Months Follow-up From First Exposure to HP802-247 in Subjects With Venous Leg Ulcer HP802-247 - Venous Leg Ulcer | Unknown | Healthpoint | 440 | 2012-09-01 | 2014-02-03 | |
| Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers HP-802-247, Vehicle - Venous Leg Ulcers | Phase 3 | Completed | Healthpoint | 447 | 2012-08-01 | 2016-03-14 |
| Using Santyl or Bacitracin on Second Degree Burns Collagenase Santyl, Bacitracin - Burn, Partial Thickness | Phase 4 | Withdrawn | Healthpoint | 2012-03-01 | 2012-05-16 | |
| A Pilot Study of HP802-247 in Dystrophic Epidermolysis Bullosa HP802-247, Placebo - Dystrophic Epidermolysis Bullosa | Phase 2 | Withdrawn | Healthpoint | 2012-03-01 | 2012-05-16 | |
| Comparison of Wound Bed Establishment in Facial Burns Enzymatic agent, Bacitracin - Burns | Phase 4 | Completed | University of Louisville | 10 | 2012-02-01 | 2017-08-28 |
| Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury HP011-101 (Xenaderm Ointment), Standard Care - Pressure Ulcers, Spinal Cord Injury | Phase 2 | Terminated | Healthpoint | 19 | 2011-09-01 | 2014-02-10 |
| Using Santyl on Diabetic Foot Ulcers Santyl, Control - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 55 | 2011-08-01 | 2014-07-24 |
| Healing Effects of HP802-247 Versus Antibiotic Ointment in Mohs Micrographic Surgery Patients HP802-247, Bacitracin Ointment - Non-melanoma Skin Cancer | Phase 2 | Completed | Healthpoint | 8 | 2011-05-01 | 2017-06-29 |
| Study to Determine if Fibrin Affects the Ability of a Wound to Heal Fibrin, White Petrolatum - Effect of Test Articles on the Healing of a Wound Artificially Induced by Liquid Nitrogen Spray | Phase 1 | Completed | Healthpoint | 40 | 2011-01-01 | 2015-12-21 |
| Wound Edge Changes Following Treatment With Santyl Collagenase Santyl Ointment, Placebo Comparator - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 10 | 2010-12-01 | 2013-05-30 |
| Study of Survival Duration for Donor Skin Cells in Skin Biopsy Wounds HP802-247 - Normal Female Volunteers | Phase 1 | Completed | Healthpoint | 28 | 2010-09-01 | 2017-07-02 |
| Enzymatic Versus (vs) Autolytic Debridement of Diabetic Foot Ulcers Santyl, Tegaderm Hydrogel - Diabetic Foot Ulcers | Phase 4 | Completed | Healthpoint | 20 | 2010-07-01 | 2013-05-31 |
| Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers Negative Pressure Wound Therapy, Collagenase Ointment - Pressure Ulcer, Soft Tissue Necrosis Lower Limb | Not applicable | Terminated | Louisiana State University Health Sciences Center Shreveport | 2 | 2010-06-01 | 2014-07-17 |
Showing 20 of 36. Sign in to see all of them.
Diabetic Foot (9) · Varicose Ulcer (9) · Ulcer (6) · Wounds and Injuries (6) · Pressure Ulcer (4) · Cicatrix (3) · Burns (2) · Leg Ulcer (2) · Varicose Veins (2) · Venous Insufficiency (2) · Venous Thrombosis (2) · Dermatitis, Phototoxic (1) · Diabetes Mellitus (1) · Diabetic Neuropathies (1) · Epidermolysis Bullosa (1)
Collagenases (6) · Standard of Care (4) · Granulex (3) · Petrolatum (3) · Bacitracin (2) · Bandages, Hydrocolloid (1) · Fibrin (1) · Hydrogels (1) · Negative-Pressure Wound Therapy (1) · Ointments (1)
United States (29) · Canada (6) · Belgium (2) · Czechia (2) · Germany (2) · Hungary (2) · Poland (2) · Puerto Rico (1)
Herbert B Slade, MD (24) · Innes Cargill, PhD (5) · Robert Kirsner, MD (4) · Tommy Lee, MSHS (4) · William Marston, MD (4) · Art J Tallis, DPM (1) · Barry Reece, MS (1) · Carl Van Gils, DPM, CWS (1) · Carlee R. Lehna, PhD, APRN-BC (1) · D. Innes Cargill, PhD (1) · Davin Haraway, DO (1) · Dhaval Bhavsar, MD (1) · Hebert B Slade, MD (1) · Hebert B Slade, MD, FAAAAI (1) · Herbert B. Slade, MD (1)
PMID 29037354, PMID 22863328, PMID 24145042, PMID 25767565, PMID 26151791