Colitis: Clinical Trials

872 completed, 269 unknown, 261 recruiting, 188 terminated. 438 Not applicable, 365 Phase 2, 240 Phase 3, 190 Phase 1, 130 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	438	Completed 184, Unknown 83, Recruiting 65, Terminated 39, Not yet recruiting 33, Active not recruiting 14, Withdrawn 11, Enrolling by invitation 6, Suspended 3
Phase 2	365	Completed 158, Terminated 62, Recruiting 56, Unknown 34, Active not recruiting 22, Withdrawn 18, Not yet recruiting 12, Enrolling by invitation 3
Phase 3	240	Completed 133, Terminated 32, Unknown 25, Recruiting 22, Active not recruiting 17, Withdrawn 6, Not yet recruiting 4, Enrolling by invitation 1
Phase 1	190	Completed 100, Terminated 25, Unknown 19, Recruiting 16, Not yet recruiting 14, Active not recruiting 7, Withdrawn 6, Enrolling by invitation 3
Phase 4	130	Completed 57, Unknown 17, Not yet recruiting 15, Recruiting 15, Terminated 15, Withdrawn 6, Active not recruiting 3, Enrolling by invitation 2
Early Phase 1	21	Unknown 8, Not yet recruiting 4, Completed 2, Recruiting 2, Terminated 2, Withdrawn 2, Enrolling by invitation 1

Follow Colitis: new trials by email Literature Review of Colitis trials Research Report on Colitis

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis High dose budesonide rectal foam, Low dose budesonide rectal foam, Matching placebo rectal foam - Ulcerative Colitis	Phase 4	Not yet recruiting	Bausch Health Americas, Inc.	100	2029-06-01	2026-10-06
ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	50	2028-01-01	2026-02-09
A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis)	Not applicable	Not yet recruiting	Nova Scotia Health Authority	70	2027-09-01	2026-09-08
Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease Digital Mind Body Intervention mobile application - Crohn's Disease, Ulcerative Colitis	Not applicable	Not yet recruiting	Montefiore Medical Center	40	2027-07-01	2026-09-14
Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue	Not applicable	Not yet recruiting	University Hospital, Grenoble	120	2027-06-01	2026-09-11
ASAPP Study - Topical 5-ASA as Prophylaxis for Pouchitis in Ulcerative Colitis Patients After Pelvic Pouch Surgery 5-ASA, Placebo - Ulcerative Colitis (UC), Pouchitis	Phase 4	Not yet recruiting	University Hospital, Linkoeping	110	2027-04-01	2026-08-19
LMT503 First-in-human SAD, MAD, and FE Study LMT503, Placebo - Inflammatory Bowel Disease, Colitis, Ulcerative	Phase 1	Not yet recruiting	Lmito Therapeutics Inc.	72	2027-03-01	2026-09-01
Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH). TRA16, Placebo - Enteric Hyperoxaluria	Phase 2	Not yet recruiting	Wuhan Kangfude Urolithiasis Research Institute Co., Ltd.	30	2027-03-01	2026-10-13
Nitazoxanide as Adjunct Therapy in Mild-to-Moderate Ulcerative Colitis Nitazoxanide (NTZ) - Ulcerative Colitis (UC)	Phase 2 / Phase 3	Not yet recruiting	Tanta University	44	2027-01-01	2026-09-15
Safety and Efficacy of a STOPping Strategy Versus Classical Maintenance Dose of JAK Inhibitors in Deep Remission Patients With Ulcerative Colitis treatment withdrawal - Ulcerative Colitis in Remission	Phase 4	Not yet recruiting	Assistance Publique Hopitaux De Marseille	224	2027-01-01	2026-07-22
Oral Aeromonas sp. MTB Phage Therapy for Pouchitis in Patients With Ulcerative Colitis (UC) MTB-targeted phage therapy - Pouchitis, UC - Ulcerative Colitis	Early Phase 1	Not yet recruiting	Jinling Hospital, China	12	2027-01-01	2026-10-22
Safety, Tolerability and PK of ATTO 1091 in Healthy Adult Volunteers and Patients With Ulcerative Colitis ATTO-1091, Placebo - Ulcerative Colitis (UC)	Phase 1	Not yet recruiting	Attovia Therapeutics Inc	96	2026-12-14	2026-09-15
The EDICT Trial - Therapy for Inflammatory Bowel Disease Flares elemental diet (ED) - Inflammatory Bowel Disease	Not applicable	Not yet recruiting	Wake Forest University Health Sciences	42	2026-12-01	2026-09-28
FirST Lines of Biologics in pAtients With ulceRaTivE Colitis: a Randomised Controlled Trial 1: infliximab 2: filgotinib 3: ustekinumab 4: vedolizumab, 1: ustekinumab 2: vedolizumab 3: infliximab 4: filgotinib, 1: vedolizumab 2: infliximab 3: filgotinib 4: ustekinumab - Ulcerative Colitis (UC)	Phase 4	Not yet recruiting	University Hospital, Clermont-Ferrand	240	2026-12-01	2026-10-21
Efficacy of Upadacitinib Re-induction Therapy in Patients With Ulcerative Colitis Who Lost Response to 30 mg Maintenance Dose Upadacitinib - Ulcerative Colitis (UC)	Phase 4	Not yet recruiting	Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives	100	2026-11-15	2026-07-31
Microbiome-targeted Diet Therapy in Ulcerative Colitis High Protein, High Fiber (HPHF) Diet - Ulcerative Colitis	Not applicable	Recruiting	University of Minnesota	40	2026-11-09	2026-10-20
Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease Inflammatory Bowel Disease, Crohn's Disease		Recruiting	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	100	2026-11-02	2026-10-28
Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis	Phase 4	Not yet recruiting	Jay C. Buckey Jr.	100	2026-11-01	2026-09-09
Validation and Clinical Impact of GLIM Criteria in Patients With Inflammatory Bowel Disease Inflammatory Bowel Diseases, Crohn Disease		Not yet recruiting	Assiut University	210	2026-11-01	2026-10-22
Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation Aquamin, Placebo - Ulcerative Colitis, Ileal Pouch	Phase 2	Recruiting	Muhammad N Aslam, MD	52	2026-11-01	2026-10-20

Showing 20 of 1896. Sign in to see all of them.

Narrower conditions

Colitis, Ulcerative (1792)  ·  Crohn Disease (678)  ·  Inflammatory Bowel Diseases (639)  ·  Arthritis, Rheumatoid (43)  ·  Irritable Bowel Syndrome (38)  ·  Arthritis, Psoriatic (35)  ·  Colorectal Neoplasms (29)  ·  Gastrointestinal Diseases (29)  ·  Spondylitis, Ankylosing (29)  ·  Ulcer (29)  ·  Psoriasis (27)  ·  Colitis, Microscopic (22)  ·  Pouchitis (22)  ·  Depression (21)

Broader conditions

Gastroenteritis (1885)  ·  Colonic Diseases (1882)  ·  Digestive System Diseases (1877)  ·  Intestinal Diseases (1876)  ·  Gastrointestinal Diseases (1867)  ·  Inflammatory Bowel Diseases (1182)  ·  Pathological Conditions, Signs and Symptoms (175)  ·  Pathologic Processes (109)  ·  Immune System Diseases (87)  ·  Neoplasms (77)  ·  Skin and Connective Tissue Diseases (77)  ·  Musculoskeletal Diseases (73)  ·  Neoplasms by Site (68)  ·  Joint Diseases (66)

Interventions

Mesalamine (88)  ·  vedolizumab (67)  ·  Infliximab (64)  ·  Fecal Microbiota Transplantation (58)  ·  Adalimumab (42)  ·  golimumab (26)  ·  Ustekinumab (20)  ·  Blood Specimen Collection (19)  ·  Budesonide (19)  ·  etrasimod (18)  ·  tofacitinib (18)  ·  mirikizumab (17)  ·  Azathioprine (16)  ·  Colonoscopy (16)  ·  Standard of Care (15)

Sponsors

Takeda (48)  ·  AbbVie (40)  ·  Pfizer (37)  ·  Janssen Research & Development, LLC (27)  ·  Bausch Health Americas, Inc. (18)  ·  Ferring Pharmaceuticals (18)  ·  Mayo Clinic (18)  ·  Bristol-Myers Squibb (17)  ·  Assiut University (16)  ·  Shire (16)  ·  Assistance Publique - Hôpitaux de Paris (14)  ·  Eli Lilly and Company (14)  ·  GlaxoSmithKline (14)  ·  Chinese University of Hong Kong (12)  ·  Merck Sharp & Dohme LLC (12)

Countries

United States (635)  ·  Canada (272)  ·  Germany (250)  ·  France (246)  ·  Poland (221)  ·  United Kingdom (214)  ·  Italy (206)  ·  Belgium (187)  ·  Netherlands (169)  ·  China (165)  ·  Hungary (165)  ·  Israel (159)  ·  Spain (155)  ·  Czechia (150)  ·  South Korea (139)

Results publications

PMID 40243391, PMID 40013523, PMID 32445184, PMID 35648151, PMID 36124702, PMID 29850873, PMID 30476584, PMID 31077827, PMID 31599001, PMID 32816215, PMID 33684552, PMID 35792493, PMID 36342120, PMID 36526796, PMID 36931693, PMID 38425446, PMID 39778975, PMID 26893500, PMID 32766762, PMID 32870265, PMID 32964215, PMID 33127596, PMID 33324993, PMID 33513294, PMID 34614208, PMID 35380664, PMID 35380740, PMID 36336750, PMID 37402275, PMID 37560161, PMID 38310565, PMID 38778549, PMID 42248437, PMID 16339095, PMID 19596014, PMID 25173754, PMID 25857665, PMID 26363929, PMID 26563167, PMID 27959607, PMID 28467869, PMID 29028981, PMID 29142515, PMID 29380251, PMID 29409871, PMID 29743836, PMID 29909019, PMID 30721964, PMID 30739254, PMID 31279870

NIH funding

2023 (29), 2017 (24), 2016 (19), 2018 (18), 2025 (17), 2015 (12), 2019 (11), 2014 (9), 2004 (5), 2009 (5), 2008 (4), P30CA060553 (2), U01DK062423 (2), U01DK062431 (2), 1IK2RD000689-01A2 (1)