171 completed, 62 unknown, 44 recruiting, 40 terminated. 222 Not applicable, 43 Phase 2, 24 Phase 1, 22 Phase 4, 19 Phase 3.
Follow Varicose Ulcer: new trials by email Literature Review of Varicose Ulcer trials Research Report on Varicose Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Subcutaneous Dexpanthenol Administration and Wound Epithelialization Dexpanthenol, Standard Wound Care - Chronic Wounds, Diabetic Foot Ulcer | Not applicable | Not yet recruiting | Dilara CANBAY OZDEMIR | 40 | 2026-12-02 | 2026-10-22 |
| Vacuum Compression Therapy and Tissue Oxygenation in Chronic Leg Ulcers Vacuum Compression Therapy (VCT), Standard Wound Care - Leg Ulcers, Leg Ulcers Venous | Not applicable | Recruiting | BTL Industries Ltd. | 20 | 2026-10-15 | 2026-10-28 |
| LUT017 Gel for Venous Leg Ulcers and Chronic Non-Healing Skin Wounds in Adults LUT017 gel - Venous Leg Ulcer, Chronic Non-Healing Cutaneous Wounds | Phase 1 | Not yet recruiting | Antoni Ribas | 18 | 2026-10-02 | 2026-05-29 |
| Dose-Response Structured Calf Muscle Pump Activation Strategies Versus Unsupervised Home Walks Dose-Response Structured CMP Activation, Active Control - Venous Ulcer of Leg | Not applicable | Recruiting | MTI University | 80 | 2026-10-01 | 2026-10-27 |
| Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Lower Extremity Ulcers PRFM - Lower Extremity, Chronic Ulcers | Phase 1 / Phase 2 | Not yet recruiting | Tiger Biosciences, LLC. | 30 | 2026-09-01 | 2026-10-07 |
| The GORE® VIABAHN® FORTEGRA Venous Stent Post-Approval Study GORE® VIABAHN® FORTEGRA Venous Stent - Venous Thromboses, Venous Disease | Not applicable | Recruiting | W.L.Gore & Associates | 150 | 2026-08-25 | 2026-10-26 |
| Noninvasive Artificial Venous Stasis for Reperfusion in STEMI STEMI - ST Elevation Myocardial Infarction | Recruiting | Firat University | 500 | 2026-08-15 | 2026-08-18 | |
| Effect of Photobiomodulation on Healing of Venous Leg Ulcers Photobiomodulation Therapy, Sham Photobiomodulation, Compression Therapy - Venous Leg Ulcer (VLU), Venous Hypertension Ulcers | Not applicable | Recruiting | University of Nove de Julho | 102 | 2026-08-03 | 2026-09-09 |
| An Open Label, Single Treatment, Single Arm, Multiple Dose Phase-2 Study to Evaluate the Pharmacokinetics, Safety, and Clinical Performance of EscharEx (EX-03) in Participants With Venous Leg Ulcers EX-03 - Venous Leg Ulcer (VLU) | Phase 2 | Not yet recruiting | MediWound Ltd | 20 | 2026-08-01 | 2026-07-09 |
| OCM™ Treatment With Routine Care in Venous Leg Ulcers Compared to Routine Care Treatment Alone. Omeza OCM™ Wound Matrix, Routine Care - Venous Leg Ulcer (VLU) | Not applicable | Not yet recruiting | Omeza, LLC | 254 | 2026-08-01 | 2026-08-10 |
| Smart Bandage With Telemonitoring vs Standard Care for Venous Leg Ulcer: Randomized Trial Smart Bandage with Telemonitoring, Conventional Bandage - Venous Leg Ulcer (VLU), Chronic Wound | Not applicable | Not yet recruiting | Asmat Burhan | 110 | 2026-07-26 | 2026-06-04 |
| Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-Heal VLUs Standard of Care (SOC), Corplex P, Theracor - Venous Leg Ulcers, Venous Leg Ulcers (VLUs) | Not applicable | Not yet recruiting | StimLabs | 272 | 2026-07-01 | 2026-03-04 |
| Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers Standard of Care, NeoThelium FT - Venous Leg Ulcer | Not applicable | Not yet recruiting | NuScience Medical Biologics, LLC | 132 | 2026-07-01 | 2026-04-13 |
| Nimsai Herbal for Grade 2-3 Hemorrhoids: A Quadruple-Blind Placebo-Controlled Mechanistic Trial Nimsai Herbal, Placebo - Hemorrhoid, Hemorrhoidal Disease | Phase 3 | Not yet recruiting | Nimsai Academia | 50 | 2026-06-22 | 2026-06-25 |
| Early vs. Late Tourniquet Release and Phlebotomy-Induced Hemolysis in the Emergency Department: TOURNI-ED Sphygmomanometer-Applied Venous Stasis with Varied Release Timing During Phlebotomy - Hemolysis, Blood Specimen Collection | Not applicable | Completed | Marmara University Pendik Training and Research Hospital | 792 | 2026-06-01 | 2026-08-27 |
| Evaluation of the Efficacy of Hyalomatrix® in the Healing of Chronic Venous Leg Ulcers Hyalomatrix, Standard of Care - Venous Leg Ulcer, Chronic Wounds | Not applicable | Recruiting | NuScience Medical Biologics, LLC | 122 | 2026-05-14 | 2026-06-30 |
| A Randomized Non-Inferiority Study of Mepi™ Press 2 vs UrgoK2® for Compression Therapy in Venous Leg Ulcers Compression bandage system (Mepi™ Press 2), Compression bandage system (UrgoK2®), Wound Dressing Material - Venous Leg Ulcer (VLU), Compression Bandages | Not applicable | Not yet recruiting | Molnlycke Health Care AB | 386 | 2026-05-01 | 2026-05-20 |
| PAW-Hydrogel for Chronic Wound Healing PAW-Functionalized Carbopol® 940 Hydrogel, Standard Advanced Wound Care - Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU) | Not applicable | Recruiting | Benjamín Gonzalo Rodríguez Méndez | 50 | 2026-04-20 | 2026-04-21 |
| Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds Motion NPWT - Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers | Not applicable | Enrolling by invitation | West Boca Center for Wound Healing | 50 | 2026-04-15 | 2026-06-17 |
| Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing dHPT, AIC - Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU) | Active not recruiting | Cellution Biologics | 300 | 2026-03-12 | 2026-08-27 |
Showing 20 of 367. Sign in to see all of them.
Diabetic Foot (74) · Leg Ulcer (51) · Pressure Ulcer (47) · Ulcer (40) · Wounds and Injuries (35) · Venous Insufficiency (24) · Varicose Veins (15) · Venous Thrombosis (13) · Surgical Wound (12) · Foot Ulcer (11) · Skin Ulcer (11) · Burns (9) · Diabetes Mellitus (5) · Postthrombotic Syndrome (5)
Skin and Connective Tissue Diseases (367) · Skin Diseases (365) · Cardiovascular Diseases (364) · Vascular Diseases (364) · Skin Ulcer (356) · Varicose Veins (352) · Leg Ulcer (316) · Endocrine System Diseases (76) · Diabetes Complications (73) · Diabetic Neuropathies (73) · Diabetes Mellitus (72) · Diabetic Angiopathies (72) · Foot Ulcer (66) · Pathological Conditions, Signs and Symptoms (65) · Pathologic Processes (56)
Standard of Care (25) · Gels (6) · Compression Bandages (5) · Bandages (4) · Low-Level Light Therapy (4) · Debridement (3) · Polidocanol (3) · Radiofrequency Ablation (3) · Apligraf (2) · Aspirin (2) · Blood Specimen Collection (2) · Cell Count (2) · Conservative Treatment (2) · Sodium Chloride (2) · Sodium Tetradecyl Sulfate (2)
Healthpoint (9) · Molnlycke Health Care AB (9) · ConvaTec Inc. (8) · Laboratoires URGO (7) · Organogenesis (7) · Smith & Nephew, Inc. (7) · Firstkind Ltd (6) · Imperial College London (5) · Kerecis Ltd. (5) · BioLab Holdings (4) · MediWound Ltd (4) · Medical University of South Carolina (4) · RHEACELL GmbH & Co. KG (4) · U.S. Wound Registry (4) · B. Braun Ltd. Centre of Excellence Infection Control (3)
United States (154) · United Kingdom (38) · France (27) · Germany (24) · Canada (21) · Italy (16) · Poland (15) · Spain (12) · Czechia (11) · Ireland (11) · Sweden (8) · Switzerland (8) · Austria (7) · Brazil (7) · Hungary (7)
William Marston, MD (8) · Herbert B Slade, MD (6) · Robert Kirsner, MD (4) · Tommy Lee, MSHS (4) · Alisha Oropallo, MD (2) · Alun H Davies (2) · Andreas Kerstan, Dr. (2) · Andrew Jull, RN PhD (2) · Angelina Ferguson, DNP (2) · Hadar Lev-Tov, MD, MAS (2) · Ian D Graham, PhD (2) · Kathleen Gibson, MD (2) · Keith Harding, MD (2) · Koen Lim (2)
PMID 29037354, PMID 26025146, PMID 30001202, PMID 3893385, PMID 10194512, PMID 10355863, PMID 10396491, PMID 11510598, PMID 1338829, PMID 15455308, PMID 15941430, PMID 16835515, PMID 16871217, PMID 17156107, PMID 19036149, PMID 19163817, PMID 20510634, PMID 20559172, PMID 21270623, PMID 21283981, PMID 21337794, PMID 21638277, PMID 21944912, PMID 21979844, PMID 21995267, PMID 22863328, PMID 22990161, PMID 23031428, PMID 23388350, PMID 2396195, PMID 24135621, PMID 24281606, PMID 24424141, PMID 24558028, PMID 25650040, PMID 25703058, PMID 25868409, PMID 26554558, PMID 26719678, PMID 26888961, PMID 26933467, PMID 26992340, PMID 26992578, PMID 26992985, PMID 27013016, PMID 27707417, PMID 27752238, PMID 27822727, PMID 28053158, PMID 28544150
2023 (1), N01AR092238 (1), R01AR046557 (1), R01AR073614 (1), R01NR012237 (1), R21AG080424 (1), R21NR012803 (1), R43HL092673 (1), R44HL145860 (1)