14 completed, 10 unknown, 5 not yet recruiting, 3 recruiting. 15 Phase 4, 12 Not applicable, 2 Phase 2, 2 Phase 3.
Follow Shivering: new trials by email Literature Review of Shivering trials Research Report on Shivering
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Paracetamol Versus Magnesium Sulfate for Control of Shivering Following Spinal Anesthesia in Cesarean Section Paracetamol, Magnesium Sulfate - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 90 | 2026-11-01 | 2026-10-02 |
| Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic Surgeries Paracetamol 2 g, Paracetamol 1 g, Normal Saline Placebo - Shivering, Postoperative Shivering | Phase 4 | Not yet recruiting | Assiut University | 150 | 2026-11-01 | 2026-10-02 |
| Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal Anesthesia Dexmedetomidine, Meperidine, Normal Saline 0.9% - Shivering, Hypothermia | Phase 4 | Not yet recruiting | Assiut University | 99 | 2026-11-01 | 2026-10-02 |
| Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section Midazolam and Ketamine, 0.9% Sodium Chloride - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 120 | 2026-11-01 | 2026-10-02 |
| Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Cesarean Section Ondansetron lozenge, Ondansetron intravenous - Ondansetron, Lozenge | Not applicable | Recruiting | Tanta University | 90 | 2026-04-11 | 2026-06-23 |
| Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy Ondansetron lozenge, Ondansetron intravenous - Ondansetron, Lozenge | Not applicable | Recruiting | Tanta University | 210 | 2026-03-25 | 2026-03-27 |
| The Effect of Warmed Socks Developed as Wearable Technology on Hypothermia, Thermal Comfort Perception and Shivering Heated socks to be developed with wearable technology - Wearable Technology, Hypothermia | Not applicable | Not yet recruiting | Tarsus University | 70 | 2025-12-15 | 2025-09-09 |
| Effect Of Acupressure On Hypothermıa And Shıverıng After Cesarean Sectıon Acupressure - Hypothermia, Shivering | Not applicable | Recruiting | Ondokuz Mayıs University | 57 | 2025-10-14 | 2026-10-07 |
| Efficacy of IV Fluid Warmer for the Prevention of Hypothermia Hypothermia, Hotline - Hypothermia, Shivering | Not applicable | Completed | Shaukat Khanum Memorial Cancer Hospital & Research Centre | 84 | 2025-03-01 | 2025-09-25 |
| Effect of Preemptive Education on the Incidence of Maternal Intraoperative Shivering in Elective Cesarean Delivery preemptive education provided by anesthesiologists - Shivering, Spinal Anesthesia | Not applicable | Unknown | Seoul National University Hospital | 130 | 2024-12-09 | 2025-05-15 |
| Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of Postoperative Shivering After General Anaesthesia for Abdominal Surgeries Hydrocortisone, Dexmedetomidine - Shivering | Phase 4 | Unknown | Ain Shams University | 70 | 2024-11-11 | 2025-09-04 |
| Role of Intravenous Dexmedetomidine in Reducing Shivering After Shivering Cesarean Section Due to Spinal Anesthesia Dexmedetomidine, Normal Saline (Placebo) - Shivering | Phase 2 | Completed | Liaquat National Hospital & Medical College | 60 | 2023-12-21 | 2024-12-02 |
| Tramadol and Tramadol Plus Ketamine for Shivering Prevention After Spinal Anesthesia in Lower Segment Caeserian Section Tramadol with Ketamine, Tramadol - Shivering | Phase 4 | Unknown | Ziauddin University | 190 | 2023-08-16 | 2023-11-18 |
| Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs Pethidine, Acetaminophen, Dexamethasone - Shivering | Phase 4 | Completed | Ain Shams University | 130 | 2022-07-01 | 2025-01-29 |
| Comparison of Prophylactic Use of Tramadol Versus Ketamine for Prevention of Post Spinal Anesthesia Shivering Tramadol, Ketamine - Shivering | Phase 3 | Completed | Syed Muhammad Abbas | 92 | 2022-06-29 | 2025-06-29 |
| Safe Brain Initiative, Operationalizing Precision Anaesthesia Patient reported ourcomes - Neurocognitive Disorders, Post Operative Delirium | Unknown | University of Southern Denmark | 15000 | 2021-12-01 | 2024-06-07 | |
| Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery Dexmedetomidine - Shivering, Dose Finding Study | Phase 4 | Withdrawn | Mayo Clinic | 2021-09-21 | 2026-09-18 | |
| Shivering_Basel_Baden Gloves filled with warm tap water - Shivering | Not applicable | Unknown | University Hospital, Basel, Switzerland | 200 | 2021-06-24 | 2024-04-22 |
| Comparison of MgSO4 Versus Meperidine for Prevention of Shivering During Spinal Anesthesia Magnesium sulfate, Meperidine - Shivering | Phase 4 | Completed | AnestesiaR | 100 | 2021-02-01 | 2021-11-08 |
| Nefopam Versus Ondansteron for Prevention of Post Spinal Shivering. Ondansetron 8mg, Nefopam Injectable Solution - Shivering, Adverse Effects in the Therapeutic Use of Anaesthetic | Phase 4 | Unknown | Saint-Joseph University | 150 | 2020-12-01 | 2021-05-03 |
Showing 20 of 34. Sign in to see all of them.
Hypothermia (6) · Anxiety Disorders (2) · Nausea (2) · Vomiting (2) · Body Temperature Changes (1) · Deaf-Blind Disorders (1) · Emergence Delirium (1) · Fasting (1) · Hypotension (1) · Neurocognitive Disorders (1) · Pain (1) · Patient Satisfaction (1) · Pharyngitis (1) · Postoperative Nausea and Vomiting (1) · Psychomotor Agitation (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Body Temperature Changes (6) · Signs and Symptoms, Digestive (3) · Mental Disorders (2) · Pathologic Processes (2) · Postoperative Complications (2) · Aberrant Motor Behavior in Dementia (1) · Abnormalities, Multiple (1) · Behavior (1) · Behavioral Symptoms (1) · Blindness (1) · Cardiovascular Diseases (1) · Confusion (1) · Congenital Abnormalities (1)
Dexmedetomidine (7) · Acetaminophen (4) · Ketamine (4) · Meperidine (3) · Ondansetron (3) · Saline Solution (3) · Dexamethasone (2) · Magnesium Sulfate (2) · Mirtazapine (2) · Sodium Chloride (2) · Tramadol (2) · dexamethasone 21-phosphate (2) · Acupressure (1) · Clonidine (1) · Hydrocortisone (1)
Assiut University (6) · Ain Shams University (5) · Seoul National University Hospital (2) · Tanta University (2) · American University of Beirut Medical Center (1) · AnestesiaR (1) · Bartłomiej Wódarski (1) · Beni-Suef University (1) · Beth Israel Deaconess Medical Center (1) · Icahn School of Medicine at Mount Sinai (1) · Liaquat National Hospital & Medical College (1) · Mahidol University (1) · Mayo Clinic (1) · Ondokuz Mayıs University (1) · Saint-Joseph University (1)
Egypt (9) · Pakistan (4) · United States (3) · Lebanon (2) · South Korea (2) · Canada (1) · Chile (1) · Denmark (1) · Indonesia (1) · Poland (1) · Switzerland (1) · Thailand (1) · Turkey (Türkiye) (1)
Alvaro Silva, MD (1) · Bigna Buddeberg, MD (1) · Felipe Martinez, M.D; M.Sc. (1) · Finn M. Radtke, Professor (1) · Galal A Al Kadi, MD (1) · Gamze Bozkul (1) · Hans Sviggum, MD (1) · Jeffery Zahn, MD (1) · Marie Aouad, MD (1) · Muhammad Arif (1) · Muhammad Q Abbas, MCPS, FCPS (1) · Nathalie Lopez, MD (1)