7 completed, 4 not yet recruiting, 3 unknown, 1 withdrawn. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Completed 7, Not yet recruiting 4, Unknown 3, Withdrawn 1 |
Follow Shivering: new trials by email Literature Review of Shivering trials Research Report on Shivering
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Paracetamol Versus Magnesium Sulfate for Control of Shivering Following Spinal Anesthesia in Cesarean Section Paracetamol, Magnesium Sulfate - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 90 | 2026-11-01 | 2026-10-02 |
| Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic Surgeries Paracetamol 2 g, Paracetamol 1 g, Normal Saline Placebo - Shivering, Postoperative Shivering | Phase 4 | Not yet recruiting | Assiut University | 150 | 2026-11-01 | 2026-10-02 |
| Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal Anesthesia Dexmedetomidine, Meperidine, Normal Saline 0.9% - Shivering, Hypothermia | Phase 4 | Not yet recruiting | Assiut University | 99 | 2026-11-01 | 2026-10-02 |
| Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section Midazolam and Ketamine, 0.9% Sodium Chloride - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 120 | 2026-11-01 | 2026-10-02 |
| Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of Postoperative Shivering After General Anaesthesia for Abdominal Surgeries Hydrocortisone, Dexmedetomidine - Shivering | Phase 4 | Unknown | Ain Shams University | 70 | 2024-11-11 | 2025-09-04 |
| Tramadol and Tramadol Plus Ketamine for Shivering Prevention After Spinal Anesthesia in Lower Segment Caeserian Section Tramadol with Ketamine, Tramadol - Shivering | Phase 4 | Unknown | Ziauddin University | 190 | 2023-08-16 | 2023-11-18 |
| Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs Pethidine, Acetaminophen, Dexamethasone - Shivering | Phase 4 | Completed | Ain Shams University | 130 | 2022-07-01 | 2025-01-29 |
| Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery Dexmedetomidine - Shivering, Dose Finding Study | Phase 4 | Withdrawn | Mayo Clinic | 2021-09-21 | 2026-09-18 | |
| Comparison of MgSO4 Versus Meperidine for Prevention of Shivering During Spinal Anesthesia Magnesium sulfate, Meperidine - Shivering | Phase 4 | Completed | AnestesiaR | 100 | 2021-02-01 | 2021-11-08 |
| Nefopam Versus Ondansteron for Prevention of Post Spinal Shivering. Ondansetron 8mg, Nefopam Injectable Solution - Shivering, Adverse Effects in the Therapeutic Use of Anaesthetic | Phase 4 | Unknown | Saint-Joseph University | 150 | 2020-12-01 | 2021-05-03 |
| Prophylactic Mirtazapine or Clonidine for Post-spinal Anesthesia Shivering Mirtazapine, Clonidine, Placebo - Shivering | Phase 4 | Completed | Ain Shams University | 300 | 2018-03-01 | 2018-09-20 |
| Prophylactic Paracetamol or Dexamethasone for Post-spinal Anesthesia Shivering Paracetamol, Dexamethasone, Placebo - Shivering | Phase 4 | Completed | Ain Shams University | 300 | 2018-03-01 | 2018-09-20 |
| Prophylactic Mirtazapine or Dexamethasone for Post-spinal Anesthesia Shivering Mirtazapine, Dexamethasone phosphate, Placebo - Shivering | Phase 4 | Completed | Ain Shams University | 300 | 2018-03-01 | 2020-12-21 |
| Dexmedetomidine, Ketamine and Dexmetedomidine-Ketamine Combination for Control of Shivering During Regional Anaethesia Dexmedetomidine, ketamine, Dexmetedomidine+Ketamine - Shivering | Phase 4 | Completed | Assiut University | 94 | 2017-10-01 | 2018-07-03 |
| Intravenous Dexmedetomidine For The Quaity Of Emergence From General Anesthesia dexmedetomidine 0.25 µg/kg IV, dexmedetomidine 0.5 µg/kg IV, dexmedetomidine 1 µg/kg IV - Anesthesia Recovery, Anesthesia Emergence | Phase 4 | Completed | American University of Beirut Medical Center | 216 | 2009-09-01 | 2018-06-27 |
Hypothermia (3)
Body Temperature Changes (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3)
Dexmedetomidine (5) · Acetaminophen (4) · Ketamine (3) · Meperidine (3) · Dexamethasone (2) · Magnesium Sulfate (2) · Mirtazapine (2) · dexamethasone 21-phosphate (2) · Clonidine (1) · Hydrocortisone (1) · Midazolam (1) · Ondansetron (1) · Saline Solution (1) · Sodium Chloride (1) · Tramadol (1)
Ain Shams University (5) · Assiut University (5) · American University of Beirut Medical Center (1) · AnestesiaR (1) · Mayo Clinic (1) · Saint-Joseph University (1) · Ziauddin University (1)
Egypt (6) · Lebanon (2) · Indonesia (1) · Pakistan (1) · United States (1)
Galal A Al Kadi, MD (1) · Hans Sviggum, MD (1) · Marie Aouad, MD (1) · Muhammad Arif (1)