330 completed, 58 unknown, 43 recruiting, 27 terminated. 244 Not applicable, 74 Phase 2, 65 Phase 3, 61 Phase 4, 16 Phase 1.
Follow Aberrant Motor Behavior in Dementia: new trials by email Literature Review of Aberrant Motor Behavior in Dementia trials Research Report on Aberrant Motor Behavior in Dementia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation Regulating Together group therapy - Autism, Intellectual Disabilities With Other Behavioral Symptoms | Not applicable | Recruiting | Children's Mercy Hospital Kansas City | 10 | 2027-10-01 | 2026-09-03 |
| A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems | Phase 1 / Phase 2 | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 70 | 2027-03-01 | 2026-05-04 |
| Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation Regulating Together group therapy - Prader-Willi Syndrome | Not applicable | Recruiting | Children's Mercy Hospital Kansas City | 10 | 2027-01-01 | 2026-09-02 |
| Manualized Assessment and Treatment Model of Challenging Behavior Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking - Problem Behavior, Aggression | Not applicable | Recruiting | Rutgers, The State University of New Jersey | 30 | 2026-12-31 | 2026-05-08 |
| Effect of Verbal De-Escalation-Based Simulation on Agitation Management, Perception of Aggression, and Impact of Aggression in Emergency Department Nurses Standard Verbal De-Escalation Training, Verbal De-Escalation-Based Simulation Training - Agitation Management, Aggression | Not applicable | Not yet recruiting | Uskudar University | 78 | 2026-10-01 | 2026-08-25 |
| Intensive Care Unit Conflict Mediation Study SEM DESTINO - Aggression, Critical Care Staff | Not applicable | Not yet recruiting | Hospital Israelita Albert Einstein | 100 | 2026-10-01 | 2026-06-02 |
| Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial Esketamine combined with dexmedetomidine, Dexmedetomidine - Dexmedetomidine, Ketamine | Phase 4 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 356 | 2026-09-28 | 2026-09-03 |
| Just-in-Time Coping Prompts for Reactive Digital Behavior in College Students Momentary coping prompt, Active control message - Emotional Regulation, Alcohol Drinking in College | Not applicable | Recruiting | University of Florida | 80 | 2026-09-21 | 2026-10-21 |
| Momentary Coping Prompts and Hair Steroids in College Students Momentary coping prompt, Active control message - Emotional Regulation, Alcohol Drinking in College | Not applicable | Recruiting | University of Florida | 80 | 2026-09-21 | 2026-10-21 |
| BRAVE Program to Improve Safety and Reduce Violence Risk in Early Psychosis BRAVE (Behavioral Response Against Violence Engagement), Treatment As Usual (TAU) - Violence Risk, Early Psychosis | Not applicable | Recruiting | Howard University | 30 | 2026-07-02 | 2026-07-29 |
| Clinical Trial of Peer Support in the ED (PCORI) Peer-Support Enhanced Agitation Code Team (PACT) - Psychomotor Agitation, Behavioral Disorder | Not applicable | Not yet recruiting | Yale University | 57870 | 2026-07-01 | 2026-05-18 |
| A Virtual Reality Mindfulness Application for Aggression in Schizophrenia Mindfulness-Based Virtual Reality Intervention - Schizophrenia Disorder, Schizoaffecitve Disorder | Not applicable | Recruiting | Manhattan Psychiatric Center | 58 | 2026-06-05 | 2026-06-10 |
| Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients Virtual reality (VR) therapy - Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients | Not applicable | Recruiting | Milton S. Hershey Medical Center | 30 | 2026-06-02 | 2026-06-22 |
| Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji Cool roof - Resting Heart Rate, Blood Glucose Control | Not applicable | Not yet recruiting | Aditi Bunker | 800 | 2026-05-18 | 2026-05-18 |
| Death, Dying, Violence and Aggression as Shown on Medical Television Series. End of Life Care, Violent Aggressive Behavior | Not yet recruiting | King's College Hospital NHS Trust | 500 | 2026-05-10 | 2026-02-18 | |
| To Evaluate the Efficacy, Safety, and Tolerability of Dronabinol Oral Solution for Agitation in Patients With Alzheimer's Disease Dronabinol Oral Solution, Placebo Control - Agitation in Dementia | Phase 2 / Phase 3 | Not yet recruiting | Benuvia Therapeutics Inc. | 140 | 2026-05-01 | 2026-02-25 |
| Effect of Daily Screen Time on Postoperative Emergence Delirium in Children Aged 2-11 Years Daily Screen Exposure Duration - Agitation, Postoperative Agitation | Recruiting | Kanuni Sultan Suleyman Training and Research Hospital | 288 | 2026-05-01 | 2026-08-05 | |
| Activation-Socialization Intervention Program for Seniors Activation and Socialization Intervention Program - Healthy | Not applicable | Enrolling by invitation | Diana Ďuricová | 200 | 2026-04-20 | 2026-04-09 |
| ED-TREAT (Early Detection and Treatment to Reduce Events With Agitation Tool) Compared to Usual Care ED-TREAT - Psychomotor Agitation, Behavioral Disorder | Not applicable | Suspended | Yale University | 26 | 2026-04-01 | 2026-03-12 |
| Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico Cool roof - Resting Heart Rate, Blood Glucose Control | Not applicable | Not yet recruiting | Aditi Bunker | 800 | 2026-04-01 | 2026-03-12 |
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Psychomotor Agitation (280) · Aggression (238) · Dementia (80) · Alzheimer Disease (71) · Depression (32) · Delirium (31) · Anxiety Disorders (29) · Psychotic Disorders (28) · Schizophrenia (28) · Pain (26) · Mental Disorders (20) · Stress Disorders, Post-Traumatic (19) · Behavior (18) · Problem Behavior (18) · Autistic Disorder (16)
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Dexmedetomidine (37) · Haloperidol (20) · Risperidone (15) · Midazolam (12) · Olanzapine (11) · Saline Solution (11) · Sodium Chloride (11) · Loxapine (10) · Standard of Care (8) · Therapeutics (8) · Valproic Acid (8) · Ketamine (7) · Transcranial Direct Current Stimulation (7) · Music Therapy (6) · Quetiapine Fumarate (6)
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PMID 37811711, PMID 40681915, PMID 41533472, PMID 41961243, PMID 39108660, PMID 41591746, PMID 23245705, PMID 23422376, PMID 24035670, PMID 27355533, PMID 29163985, PMID 31708380, PMID 32880104, PMID 34532852, PMID 35040231, PMID 35703367, PMID 36002761, PMID 40847656, PMID 41439450, PMID 41689409, PMID 42052145, PMID 42502037, PMID 10692189, PMID 11001602, PMID 11087767, PMID 11133600, PMID 11442853, PMID 11473855, PMID 11604980, PMID 12040306, PMID 1403624, PMID 15114210, PMID 15840076, PMID 16051730, PMID 16247923, PMID 16635934, PMID 16677266, PMID 16754835, PMID 16879517, PMID 17035647, PMID 17383013, PMID 17416907, PMID 17574755, PMID 17917554, PMID 17954514, PMID 17984395, PMID 17991818, PMID 18519523, PMID 18678595, PMID 18794642
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