669 completed, 183 unknown, 96 recruiting, 75 terminated. 579 Not applicable, 101 Phase 3, 88 Phase 2, 72 Phase 4, 47 Phase 1.
Follow Body Temperature Changes: new trials by email Literature Review of Body Temperature Changes trials Research Report on Body Temperature Changes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Work Design Interventions for Older Workers During Consecutive Days in the Heat Standard work pace, Additional rest breaks - Hyperthermia, Fatigue; Heat | Not applicable | Not yet recruiting | State University of New York at Buffalo | 32 | 2028-09-01 | 2026-06-30 |
| Work Design Interventions for Heat Resilience Standard work pace, Reduced-pace work, Increased-pace work - Hyperthermia, Fatigue; Heat | Not applicable | Not yet recruiting | State University of New York at Buffalo | 32 | 2027-09-01 | 2026-06-30 |
| A Prospective Study of Concurrent Hyperthermia, Chemotherapy and Radiotherapy in Borderline and Locally Advanced Pancreatic Cancer (PANHEAT) Hyperthermia plus neoadjuvant chemotherapy/radiotherapy Arm Description: Hyperthermia plus neoadjuvant chemotherapy (mFOLFIRINOX/nab Paclitaxel) followed by a) surgically resectable: Hyp - Borderline and Locally Advanced Pancreatic Cancer | Not applicable | Not yet recruiting | Fernando Pessoa Canarias University | 60 | 2027-03-31 | 2026-09-24 |
| Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain serial whole body hyperthermia - Hyperthermia, Chronic Primary Pain | Not applicable | Not yet recruiting | Bern University of Applied Sciences | 60 | 2026-12-01 | 2026-09-30 |
| Mild-Intensity Whole Body Hyperthermia (WBH) for Major Depressive Disorder Tocilizumab, Placebo, Whole-Body Hyperthermia - Major Depressive Disorder | Phase 2 | Suspended | Massachusetts General Hospital | 35 | 2026-12-01 | 2025-11-13 |
| Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study Cognitive Behavioral Therapy (CBT), Whole-Body Hyperthermia - Major Depressive Disorder | Not applicable | Not yet recruiting | University of California, San Francisco | 60 | 2026-12-01 | 2026-10-13 |
| Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic Surgeries Paracetamol 2 g, Paracetamol 1 g, Normal Saline Placebo - Shivering, Postoperative Shivering | Phase 4 | Not yet recruiting | Assiut University | 150 | 2026-11-01 | 2026-10-02 |
| Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal Anesthesia Dexmedetomidine, Meperidine, Normal Saline 0.9% - Shivering, Hypothermia | Phase 4 | Not yet recruiting | Assiut University | 99 | 2026-11-01 | 2026-10-02 |
| Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section Midazolam and Ketamine, 0.9% Sodium Chloride - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 120 | 2026-11-01 | 2026-10-02 |
| TECAR Therapy in Chronic Back Pain TECAR Therapy plus Hi-EMS, Tecar therapy alone - Chronic Low-back Pain (cLBP), Non Specific Chronic Low Back Pain | Not applicable | Not yet recruiting | University of Hartford | 37 | 2026-10-19 | 2026-09-15 |
| Progressive Heat Exposure and Physiological Strain Constant Heat Exposure, Progressively Increasing Heat Exposure - Body Temperature Changes, Heat Stress | Not applicable | Not yet recruiting | University of Ottawa | 14 | 2026-10-01 | 2026-09-29 |
| Intratumoral Targeted Hyperthermia Therapy (THT) for Cutaneous Metastatic Melanoma Targeted Hyperthermia Therapy - Cutaneous Metastatic Melanoma | Not applicable | Not yet recruiting | Sona Nanotech Inc | 10 | 2026-10-01 | 2026-04-24 |
| A Study Comparing Whole-Body Heat Treatment Plus Systemic Therapy to Systemic Therapy Alone, for Advanced Pancreatic Cancer Whole-body hyperthermia, Standard-of-Care Systemic therapy - Pancreatic Ductal Adenocarcinoma (mPDAC), Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) | Phase 2 / Phase 3 | Not yet recruiting | ElmediX | 95 | 2026-10-01 | 2026-07-17 |
| Rapid Cool: Heat Stroke Treatment Recirculated water, Phoenix protocol - Hyperthermia | Not applicable | Not yet recruiting | State University of New York at Buffalo | 20 | 2026-09-21 | 2026-08-04 |
| Effect of an Intervention Combining the Use of Standardized Information and Sending an SMS Advice Message to Parents Calling the SAMU Center 15 for Uncomplicated Fever in Children Standardized recommendations during emergency calls and sending advisory text message - Emergency Call, Fever; Pediatric Fever Management; Parental Anxiety | Not applicable | Not yet recruiting | Centre Hospitalier Annecy Genevois | 1792 | 2026-09-07 | 2025-12-02 |
| Thermotherapy for Head and Neck Cancer Patients Thermotherapy, Radiotherapy, Concurrent chemoradiation - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Recruiting | Erasmus Medical Center | 30 | 2026-09-01 | 2026-09-02 |
| Hyperthermia Safety Study Uses Temperature Management System to Gently Raise Participant's Body Temperature to a Fever-range Level in a Controlled Setting. Hyperthermia - Safety Study | Not applicable | Enrolling by invitation | Marc Abreu | 20 | 2026-09-01 | 2026-09-21 |
| Continuous Monitoring of Body Temperature in Neonates During Therapeutic Hypothermia continous temperature measurement - Therapeutic Hypothermia, Neonatal Hypoxic-Ischemic Encephalopathy | Recruiting | Medical University of Graz | 10 | 2026-08-05 | 2026-10-06 | |
| Efficacy and Safety of Daily Home-based Hyperthermic Baths for Reducing Epileptic Seizures in CDKL5 Deficiency Disorder: A PROBE Clinical Trial Home-based hyperthermic Baths - CDKL5 Deficiency Disorder | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 34 | 2026-08-01 | 2026-05-22 |
| Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department Ministry of Health three-level color-coded triage - Fever, Triage | Recruiting | TC Erciyes University | 3000 | 2026-07-28 | 2026-08-05 |
Showing 20 of 1144. Sign in to see all of them.
Fever (417) · Hypothermia (395) · Hyperthermia (254) · Heart Arrest (49) · Neutropenia (43) · Heat Stress Disorders (33) · Neoplasms (32) · Pain (32) · Infections (31) · Malaria (24) · Sepsis (24) · Fever of Unknown Origin (21) · Cough (20) · Ischemic Stroke (20)
Pathological Conditions, Signs and Symptoms (1143) · Signs and Symptoms (1136) · Wounds and Injuries (290) · Heat Stress Disorders (229) · Pathologic Processes (226) · Infections (178) · Cardiovascular Diseases (154) · Nervous System Diseases (154) · Neurologic Manifestations (110) · Vascular Diseases (99) · Central Nervous System Diseases (94) · Neoplasms (89) · Respiratory Tract Diseases (82) · Brain Diseases (78)
Diathermy (49) · Acetaminophen (44) · Ibuprofen (23) · Hypothermia, Induced (21) · Radiotherapy (13) · Standard of Care (12) · Hyperthermia, Induced (11) · Exercise (9) · Sodium Chloride (9) · Control Groups (7) · Electrosurgery (7) · Saline Solution (7) · Ciprofloxacin (6) · Cisplatin (5) · Drug Therapy (5)
University of Ottawa (21) · Assistance Publique - Hôpitaux de Paris (13) · University of Texas Southwestern Medical Center (13) · University of Alabama at Birmingham (12) · State University of New York at Buffalo (10) · Assaf-Harofeh Medical Center (9) · Duke University (9) · National Cancer Institute (NCI) (9) · Seoul National University Hospital (8) · The Cleveland Clinic (8) · University of Connecticut (8) · Haukeland University Hospital (7) · Medical University of Vienna (7) · Medtronic Surgical Technologies (7) · Stanford University (7)
United States (282) · Canada (66) · Turkey (Türkiye) (66) · Germany (64) · France (61) · China (57) · United Kingdom (45) · Italy (44) · Israel (37) · Spain (33) · South Korea (32) · Switzerland (32) · Brazil (24) · Belgium (23) · Denmark (23)
Glen P Kenny, PhD (12) · Waldemar A Carlo, MD (10) · Seetha Shankaran, MD (5) · Sven Poli, Dr. med. (5) · Abhik Das, PhD (4) · James Faulkner, PhD (4) · Karen Broder, MD (4) · Barbara J. Stoll, MD (3) · Brenda B. Poindexter, MD MS (3) · Douglas Casa, PhD (3) · Holger Thiele, Associate Professor (3)
PMID 24524452, PMID 35835616, PMID 11812709, PMID 19502035, PMID 20042442, PMID 22520120, PMID 24188226, PMID 35639525, PMID 7879935, PMID 10325708, PMID 10763759, PMID 11234459, PMID 11703564, PMID 11707791, PMID 11856793, PMID 11856794, PMID 12127221, PMID 12165594, PMID 12697600, PMID 12719051, PMID 12768180, PMID 12771566, PMID 12847056, PMID 12937509, PMID 14666667, PMID 14964587, PMID 15271236, PMID 15294399, PMID 15459300, PMID 15721471, PMID 15806544, PMID 15861196, PMID 15885291, PMID 15885292, PMID 15970955, PMID 16060582, PMID 16091763, PMID 1610573, PMID 16199715, PMID 16221780, PMID 1622910, PMID 16324990, PMID 16398377, PMID 16533632, PMID 16558145, PMID 16558418, PMID 16558608, PMID 17079582, PMID 17296783, PMID 17342966
U10HD021364 (4), U10HD021373 (4), U10HD021385 (4), U10HD027851 (4), U10HD027853 (4), U10HD027856 (4), U10HD027880 (4), U10HD027904 (4), U10HD034216 (4), U10HD040492 (4), U10HD040689 (4), 2015 (3), U10HD027871 (3), U10HD036790 (3), U10HD053109 (3)