413 completed, 107 unknown, 88 recruiting, 25 not yet recruiting. 479 Not applicable, 85 Phase 1, 18 Phase 2, 13 Phase 4, 7 Early Phase 1.
Follow Fasting: new trials by email Literature Review of Fasting trials Research Report on Fasting
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intermittent Fasting for Pancreatitis Intermittent Fasting, No intermittent fasting - Pancreatitis, Pancreatitis, Acute | Not applicable | Not yet recruiting | H. Lee Moffitt Cancer Center and Research Institute | 64 | 2027-09-01 | 2026-09-17 |
| Exercise and Prolonged Fasting to Improve Brown Adipose Tissue Function in Postmenopausal Women Aerobic exercise, Prolonged fasting - Cardiometabolic Diseases, Postmenopause | Not applicable | Not yet recruiting | Universidad de Almeria | 60 | 2027-09-01 | 2026-09-23 |
| Mitophagy and Mitochondrial DNA Dynamics During Ramadan Dry Fasting vs 16:8 Time-Restricted Feeding Ramadan Intermittent Dry Fasting (Sawm), 16:8 Time-Restricted Feeding (TRF) - Mitochondrial Degradation, Autophagy | Not yet recruiting | Bahcesehir Cyprus University | 120 | 2027-01-15 | 2026-06-11 | |
| Time-Restricted Eating as a Dietary Intervention for Polyendocrine Metabolic Ovarian Syndrome (PMOS): Protocol for a Randomized Controlled Trial Time-restricted eating - Polycystic Ovary Syndrome | Not applicable | Not yet recruiting | Joanna Bajerska | 84 | 2027-01-09 | 2026-10-16 |
| Chrono-Fasting in Overweight and Obese Adolescents Early TRF, late TRF, Control - Obesity | Not applicable | Not yet recruiting | University of Thessaly | 120 | 2027-01-01 | 2026-08-12 |
| 24-hour Clear Liquid Diet vs. Standard Fasting for Upper Gastrointestinal Endoscopy in Patients Taking Agonists of the GLP-1 Receptor 24-Hour Clear Liquid Diet, Standard Fasting - Retained Gastric Content, Delayed Gastric Emptying | Not applicable | Not yet recruiting | Portuguese Oncology Institute, Coimbra | 250 | 2027-01-01 | 2026-11-10 |
| Early Time-Restricted Eating for Cardiovascular Health Early Time-Restricted Eating (eTRE) - Hypertension, Breakfast Skipper | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 36 | 2026-11-30 | 2026-09-28 |
| Time-Restricted Eating and Personalized Energy-Restricted Diet in Obese Postmenopausal Women Time-Restricted Eating, Personalized Energy-Restricted Diet - Obesity (BMI Equal to or >30), Postmenopausal Symptoms | Not applicable | Not yet recruiting | Gazi University | 40 | 2026-11-01 | 2026-10-19 |
| Time-restricted Eating and High-intensity Interval Training After Gestational Diabetes Time-restricted eating and exercise - Gestational Diabetes Mellitus With Baby Delivered | Not applicable | Not yet recruiting | Norwegian University of Science and Technology | 56 | 2026-11-01 | 2026-10-15 |
| Targeting HealthY Eating to Maintain Energy While Living With Cancer Nutrition counseling, Time-restricted eating - Fatigue in Cancer Survivors | Phase 2 | Recruiting | University of Maryland, Baltimore | 132 | 2026-11-01 | 2026-11-03 |
| 16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer 16-Hour Fasting, Serplulimab + chemotherapy - pMMR/MSS, Locally Advanced Rectal Carcinoma | Phase 2 | Not yet recruiting | Zhejiang University | 51 | 2026-10-01 | 2026-09-08 |
| Time Restricted Eating (TRE) in Bipolar Disorder Time Restricted Eating - Bipolar Disorder (BD), Bipolar Disorder Depression | Not applicable | Recruiting | Massachusetts General Hospital | 40 | 2026-09-01 | 2026-11-10 |
| Ketosis, Immune Function and Metabolic Adaptation in Response to Short-term Fasting in Critical Illness Delayed nutrition, Standard nutrition, Fasting - Critical Illness, Fasting State | Not applicable | Not yet recruiting | Karolinska University Hospital | 200 | 2026-08-31 | 2026-09-01 |
| Combining Fasting and Fibre Interventions to Optimise Their Gut Microbiome-mediated Health Benefits Fibre Arm, Control Arm - Fasting, Dietary Fibre | Not applicable | Recruiting | Buchinger Wilhelmi Development & Holding GmbH | 75 | 2026-08-31 | 2026-09-30 |
| Cognitive Behavioral Therapy for Insomnia as an Adjunct to Time-restricted Eating on Weight Loss in Adults With Overweight or Obesity and Chronic Insomnia Flexible Time-restricted eating group (FTRE), Flexible Time-restricted eating plus cognitive behavioural therapy for insomnia group (CBTI+FTRE) - Chronic Insomnia, Overweight/Obesity | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 50 | 2026-08-25 | 2026-08-18 |
| Effect of Meal Timing During Adjuvant Treatment for Cancer Time-restricted eating, Questionnaire Administration, Biospecimen Collection - Cancer | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 50 | 2026-08-12 | 2026-08-25 |
| Effect of macaúba Oil Combined With Green Exercises Macauba oil, Placebo, Daytime Green Exercise - Stress Mental, Dyslipidemia | Not applicable | Not yet recruiting | Federal University of Minas Gerais | 60 | 2026-08-01 | 2026-07-20 |
| Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes Phenotype-Matched Dietary Protocol, Structured Progressive Exercise Protocol, Targeted Nutritional Supplementation - Type 2 Diabetes Mellitus (T2DM), Insulin Resistance | Not applicable | Enrolling by invitation | Salah Snouda | 150 | 2026-08-01 | 2026-08-18 |
| Clinical Study on High-fiber Diet and Short-term Fasting in Melanoma Under Immunotherapy With Checkpoint Inhibition High-Fiber Diet, High-Fiber Diet and Short-Term Fasting - Melanoma (Skin Cancer) | Not applicable | Recruiting | Charite University, Berlin, Germany | 60 | 2026-07-28 | 2026-07-29 |
| Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial Time-restricted eating, Questionnaire Administration, Biospecimen Collection - Rectal Cancer Stage II, Rectal Cancer Stage III | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 100 | 2026-07-23 | 2026-07-29 |
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Intermittent Fasting (333) · Obesity (131) · Overweight (64) · Weight Loss (40) · Insulin Resistance (36) · Diabetes Mellitus, Type 2 (35) · Metabolic Syndrome (34) · Diabetes Mellitus (24) · Motor Activity (21) · Non-alcoholic Fatty Liver Disease (19) · Inflammation (18) · Prediabetic State (17) · Lecithin Cholesterol Acyltransferase Deficiency (16) · Hypertension (15)
Behavior (681) · Feeding Behavior (671) · Nutritional and Metabolic Diseases (257) · Pathological Conditions, Signs and Symptoms (235) · Signs and Symptoms (192) · Metabolic Diseases (158) · Body Weight (155) · Nutrition Disorders (149) · Overnutrition (146) · Glucose Metabolism Disorders (128) · Endocrine System Diseases (88) · Overweight (83) · Pathologic Processes (64) · Hyperinsulinism (63)
Angptl4 protein, mouse (46) · Caloric Restriction (17) · Diet (13) · Diet, Mediterranean (12) · Exercise (10) · Standard of Care (9) · Diet, Ketogenic (8) · Control Groups (7) · High-Intensity Interval Training (6) · Metformin (6) · Diet Therapy (5) · Trehalase (5) · Carbohydrates (4) · Meals (4) · Ultrasonography (4)
Par Pharmaceutical, Inc. (19) · Charite University, Berlin, Germany (17) · Dr. Reddy's Laboratories Limited (12) · IPCA Laboratories Ltd. (12) · University of California, San Diego (12) · Massachusetts General Hospital (7) · Beth Israel Deaconess Medical Center (6) · University of Aarhus (6) · University of Toronto (6) · Nanfang Hospital, Southern Medical University (5) · University of Illinois at Chicago (5) · University of Monastir (5) · Assistance Publique - Hôpitaux de Paris (4) · King's College Hospital NHS Trust (4) · Leiden University Medical Center (4)
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Andreas Michalsen, Prof. Dr. (10) · Pam Taub, MD (7) · Dr. Hardik Dave, M.B.B.S (4) · Eric Masson, Pharm.D. (3) · Huijie Zhang, MD,PhD (3) · Michael N Sack, M.D. (3) · Semir Nouira, Professor (3) · Alaina Vidmar, MD (2) · Alberto Montesanto (2) · Alessio Nencioni, MD (2) · Anthony R Godfrey, Pharm.D. (2) · Antonio Paoli, MD (2) · Benjamin D Horne, PhD, MPH (2) · Christian Aumais (2)
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P50CA285275 (2), 2015 (1), 2016 (1), 2017 (1), 2019 (1), 2023 (1), K23DK134801 (1), K23HD108345 (1), K23MH118418 (1), K99HL163474 (1), KL2TR000450 (1), M01RR001032 (1), P30AG028740 (1), P30DK020541 (1), P30DK116074 (1)