56 completed. 56 Phase 3, 16 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 56 | Completed 56 |
| Phase 2 | 16 | Completed 16 |
Follow Septic Shock: new trials by email Literature Review of Septic Shock trials Research Report on Septic Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adjunctive Methylene Blue in Septic Shock Methylene Blue, Usual Care - Septic Shock | Phase 3 | Completed | Dr. Shannon M. Fernando | 50 | 2025-06-02 | 2026-03-19 |
| A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02) VBI-S - Septic Shock, Sepsis | Phase 3 | Completed | Vivacelle Bio | 39 | 2024-08-06 | 2026-10-26 |
| Methylene Blue for the Treatment of Septic Shock Methylene Blue, Placebo - Septic Shock | Phase 3 | Completed | Northern Jiangsu People's Hospital | 88 | 2024-08-05 | 2026-02-04 |
| The Effect of Early Norepinephrine on Stroke Volume Index, Cardiac Index, Lactate, and Arterial Elastance in Pediatric Septic Shock Norepinephrine, Ringer's Lactate - Septic Shock, Sepsis | Phase 2 / Phase 3 | Completed | Universitas Indonesia | 42 | 2024-03-25 | 2024-06-20 |
| Strong Albumin Solutions in Patients With Septic Shock hyperoncotic human albumin solution, Buffered crystalloid solutions - Sepsis, Septic Shock | Phase 2 / Phase 3 | Completed | Manchester University NHS Foundation Trust | 47 | 2023-11-10 | 2026-02-09 |
| Low Dose Versus High Dose Methylene Blue in Septic Patients Normal saline, Methylene Blue low dose, Methylene Blue high dose - Septic Shock | Phase 2 / Phase 3 | Completed | National Cancer Institute, Egypt | 90 | 2023-08-01 | 2024-07-05 |
| The Effect Of Resuscitation Guided By Two Different Dynamic Parameters On Time To Normalization Of The Capillary Refill Time In Adult Patients With Septic Shock Group VTI, Group IVC - Septic Shock, Resuscitation | Phase 3 | Completed | Kasr El Aini Hospital | 90 | 2023-07-21 | 2025-04-29 |
| Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments Vitamin C, Normal saline - Sepsis, Septic Shock | Phase 3 | Completed | Universitaire Ziekenhuizen KU Leuven | 301 | 2021-06-01 | 2024-01-25 |
| Ivabradine for Heart Rate Control In Septic Shock Ivabradine, Placebo - Septic Shock | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 429 | 2021-02-26 | 2026-09-03 |
| An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19 Standard therapy recommended by the Ministry of Health of the Russian Federation., Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin intramuscular injection, Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin inhalation - Acute Respiratory Tract Infection, Acute Respiratory Insufficiency | Phase 3 | Completed | Burnasyan Federal Medical Biophysical Center | 320 | 2020-04-08 | 2021-10-13 |
| Esomeprazole to Reduce Organ Failure in Sepsis Esomeprazole, Placebo - Sepsis, Septic Shock | Phase 3 | Completed | Università Vita-Salute San Raffaele | 300 | 2020-01-28 | 2024-01-19 |
| Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in Patients With Septic Shock Suffering From Organ Failure Iloprost, Isotonic saline - Septic Shock | Phase 2 / Phase 3 | Completed | Jakob Stensballe, MD, PhD | 279 | 2019-10-30 | 2024-05-07 |
| Utility of Sodium Lactate Infusion During Septic Shock Sodium Lactate light dose, Sodium Lactate high dose, Normal saline - Septic Shock | Phase 2 / Phase 3 | Completed | University Hospital, Lille | 59 | 2019-10-04 | 2025-12-11 |
| Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis Vitamin C, Hydrocortisone, Complex B - Sepsis, Septic Shock | Phase 3 | Completed | IMSS Hospital General de Zona 11, Piedras Negras | 19 | 2019-09-01 | 2020-10-19 |
| Triple Therapy in Septic Shock Patients vitamin c - thiamine- hydrocortisone - Septic Shock, Sepsis | Phase 3 | Completed | Air Force Specialized Hospital, Cairo, Egypt | 94 | 2019-08-01 | 2021-01-26 |
| ALBumin Italian Outcome Septic Shock-BALANCED Trial (ALBIOSS-BALANCED) Albumin, Balanced - Septic Shock | Phase 3 | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 1319 | 2019-05-07 | 2025-03-05 |
| TRANSfusion in Patients With Onco-hematological Malignancies ResusciTated From Septic Shock Liberal Red blood cell transfusion, Restrictive Red blood cell transfusion - Septic Shock, Anemia | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 192 | 2019-03-24 | 2024-06-25 |
| Lidocaine-Ketamine Versus Ketamine for Induction of Anesthesia in Septic Shock Patients ketamine full dose, Midazolam, Normal saline - Septic Shock | Phase 3 | Completed | Cairo University | 43 | 2019-02-20 | 2019-11-26 |
| Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock Vitamin C,thiamine,hydrocortisone, Placebo - Septic Shock | Phase 3 | Completed | Northern Jiangsu People's Hospital | 408 | 2019-02-19 | 2021-09-23 |
| Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock red blood cells transfusion, tranexamic acid (TXA) and fibrinogen concentrate, on crystalloid fluid and Tranexamic acid - Sepsis, Septic Shock | Phase 3 | Completed | Cristina Martinez | 40 | 2018-10-31 | 2023-10-06 |
Showing 20 of 56. Sign in to see all of them.
Shock, Septic (56) · Sepsis (33) · Acute Kidney Injury (2) · Critical Illness (2) · Infections (2) · Adrenal Insufficiency (1) · Anemia (1) · Bacteremia (1) · Diabetes Insipidus (1) · Fibrosis (1) · Hemostatic Disorders (1) · Hyperglycemia (1) · Hypoalbuminemia (1) · Hypovolemia (1) · Hypoxia (1)
Inflammation (56) · Pathologic Processes (56) · Pathological Conditions, Signs and Symptoms (56) · Systemic Inflammatory Response Syndrome (56) · Shock (55) · Infections (54) · Sepsis (23) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Kidney Diseases (3) · Lung Diseases (3) · Male Urogenital Diseases (3) · Respiratory Tract Diseases (3)
Saline Solution (7) · Hydrocortisone (6) · Ascorbic Acid (5) · Norepinephrine (5) · Methylene Blue (4) · Ringer's Lactate (4) · Sodium Chloride (4) · Albumins (3) · Fludrocortisone (2) · Hydroxyethyl Starch Derivatives (2) · Ketamine (2) · Meropenem (2) · Thiamine (2) · sterofundin (2) · Arginine Vasopressin (1)
University of Versailles (3) · Assistance Publique - Hôpitaux de Paris (2) · Beth Israel Deaconess Medical Center (2) · Cairo University (2) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (2) · Frisius Medisch Centrum (2) · Kompetenznetz Sepsis (2) · Northern Jiangsu People's Hospital (2) · University of Roma La Sapienza (2) · Air Force Specialized Hospital, Cairo, Egypt (1) · Anders Perner (1) · Burnasyan Federal Medical Biophysical Center (1) · Centre Hospitalier Universitaire de Besancon (1) · Chulalongkorn University (1) · Cristina Martinez (1)
France (10) · Italy (6) · United States (6) · Egypt (5) · Canada (4) · Denmark (3) · Germany (3) · Netherlands (3) · Brazil (2) · China (2) · Finland (2) · Mexico (2) · Norway (2) · Russia (2) · Spain (2)
Anders Perner, MD, PhD (2) · Andrea Morelli, MD (2) · Konrad Reinhart, MD (2) · Luciano Gattinoni, MD (2) · Michael W Donnino, MD (2) · Pietro Caironi, MD (2) · Qingquan Lyu, Master (2) · Thomas Deufel, MD (2) · Abdelrhman Hussein (1) · Ahmed Mukhtar, Professor (1) · Alain Cariou, MD (1) · Anthony Gordon, MD FRCA (1) · Antonio Pesenti, MD (1) · Apostolos Armaganidis, MD (1)
PMID 23984731, PMID 24635772, PMID 16978417, PMID 17720019, PMID 18184958, PMID 19114908, PMID 19730258, PMID 19851126, PMID 20103758, PMID 20594297, PMID 20924555, PMID 21129208, PMID 21516036, PMID 21615299, PMID 21827677, PMID 21929764, PMID 22692171, PMID 22738085, PMID 23352693, PMID 23353941, PMID 23525934, PMID 24037226, PMID 24207137, PMID 24794878, PMID 24807084, PMID 25099709, PMID 25270275, PMID 25407570, PMID 25855898, PMID 25862039, PMID 25907781, PMID 26847922, PMID 27428731, PMID 27876084, PMID 28274246, PMID 28367008, PMID 28411114, PMID 28729329, PMID 29379043, PMID 29490185, PMID 29499723, PMID 29753517, PMID 29766091, PMID 29768150, PMID 29787743, PMID 30261898, PMID 31102938, PMID 31609774, PMID 31783881, PMID 31852712
2018 (2), 2005 (1), 2014 (1), 2017 (1), 2019 (1)