42 completed, 10 recruiting, 9 unknown, 2 withdrawn. 16 Not applicable, 8 Phase 4, 4 Phase 3, 1 Phase 1, 1 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness and Safety of Uptitration of Guideline Directed MEdical Therapy in Heart Failure With Reduced Ejection Fraction With Limited Kidney Function Assessments Blinded kidney function assessments - Heart Failure, Heart Failure and Reduced Ejection Fraction | Not applicable | Not yet recruiting | University Medical Center Groningen | 344 | 2026-04-01 | 2025-12-18 |
| Effectiveness of a Combined e-Learning and Virtual Reality Training Program for Healthcare Providers in Rheumatology Expectancy-based communication training for healthcare providers - Rheumatic Diseases | Not applicable | Recruiting | Leiden University | 936 | 2025-03-27 | 2026-09-22 |
| Can we 'Hear' Femoral Neck Fractures? Ultrasound Guided Diagnosis of Femoral Neck Fractures POCUS of the hip - Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures) | Not applicable | Completed | Frisius Medisch Centrum | 146 | 2025-01-11 | 2026-07-23 |
| Feasibility of TEE During Cardiac Arrest in Dutch Emergency Departments Transoesophageal echocardiography (TEE) - Cardiac Arrest | Not applicable | Unknown | Frisius Medisch Centrum | 30 | 2024-06-25 | 2024-06-27 |
| Identifying Diabetes and Impaired Glucose Tolerance in ICU Patients Diabetes (DM), Critical Illness | Completed | University Medical Center Groningen | 4198 | 2024-05-01 | 2026-05-04 | |
| Potassium Correction for RAAS Optimization in Chronic Kidney Disease Patiromer 8400 MG [Veltassa], Placebo - Chronic Kidney Diseases, Hyperkalemia | Phase 4 | Recruiting | University Medical Center Groningen | 44 | 2024-04-01 | 2025-12-19 |
| Hand and Arm Rehabilitation Using VR VR training for arm and hand rehabilitation - Post-Intensive Care Syndrome, ICU Acquired Weakness | Not applicable | Recruiting | Frisius Medisch Centrum | 108 | 2024-01-15 | 2024-04-18 |
| Ultrasound Guided Hematoma Block in Distal Radius Fractures Ultrasound guided hematoma block., Blind hematoma block - Distal Radius Fractures, Fracture Dislocation | Not applicable | Unknown | Frisius Medisch Centrum | 40 | 2024-01-05 | 2024-03-19 |
| ED Airway Management in the Netherlands. Endotracheal intubation - Endotracheal Intubation | Recruiting | Frisius Medisch Centrum | 1000 | 2024-01-01 | 2024-08-23 | |
| Focus on Experienced Anxiety Related to an Emergency Department Visit Questionnaire - Fear | Completed | Frisius Medisch Centrum | 139 | 2023-11-08 | 2024-03-13 | |
| Evaluation of Different Methods to Measure Muscle Mass and Strength in a Population With Class II/III Obesity Ultrasonography, Dual-energy X-ray Absorptiometry - Obesity, Morbid | Completed | Frisius Medisch Centrum | 35 | 2023-06-27 | 2025-05-09 | |
| Micronutrient Levels and Nutritional Status in Critical Illness No intervention - Post Intensive Care Unit Syndrome, Malnutrition | Completed | Frisius Medisch Centrum | 79 | 2023-05-08 | 2024-11-21 | |
| Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection Clindamycin, Rifampicin and levofloxacin - Prosthetic-joint Infection, Infection Hip | Phase 4 | Recruiting | Leiden University Medical Center | 316 | 2023-04-01 | 2023-12-15 |
| Bifurcation PCI With a Hybrid Strategy With Drug Eluting Balloons Versus a Stepwise Provisional Two-stent Strategy Hybrid DEB approach with drug-eluting balloon, Two-stent strategy - Coronary Artery Disease, Coronary Bifurcation Lesion | Not applicable | Recruiting | Cathreine BV | 500 | 2023-03-21 | 2023-12-15 |
| Clinical Relevance of Small Airways Disease in Severe Asthma Patients Treated With Anti-InterLeukin-5 Therapy Asthma | Unknown | Frisius Medisch Centrum | 110 | 2022-12-02 | 2023-01-31 | |
| Thoracoscopic Laser Speckle Contrast Imaging for Segment Resections Laser Speckle Contrast Imaging using the PerfusiX-Imaging Device - Pulmonary Cancer | Unknown | Frisius Medisch Centrum | 10 | 2022-11-01 | 2023-01-09 | |
| Laser Speckle Contrast Imaging, Surgical Eye & ICG Fluorescence Imaging for Perfusion Assessment of the Gastric Conduit Laser Speckle Contrast Imaging using the PerfusiX-Imaging device - Oesophageal Cancer | Unknown | Frisius Medisch Centrum | 30 | 2022-09-26 | 2023-01-17 | |
| Craving to Biologics Used in Severe Asthma Asthma | Completed | Frisius Medisch Centrum | 150 | 2021-12-10 | 2022-08-24 | |
| Improving Recovery After Critical Illness Group physical therapy and dietary improvements - Post Intensive Care Unit Syndrome, Critical Illness | Not applicable | Unknown | Frisius Medisch Centrum | 40 | 2021-09-01 | 2024-01-18 |
| Ultrasound Guided Axillary Nerve Block Compared to Hematoma Block in Patients With Closed Reposition of Distal Forearm Fractures Axillary plexus nerve block, Fracture hematoma block - Distal Radius Fracture, Forearm Fracture | Not applicable | Completed | Frisius Medisch Centrum | 117 | 2021-07-01 | 2023-11-29 |
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Critical Illness (6) · Emergencies (5) · Sepsis (5) · Malnutrition (3) · Shock, Septic (3) · Asthma (2) · Esophageal Neoplasms (2) · Heart Arrest (2) · Hypernatremia (2) · Ventricular Dysfunction, Right (2) · Wrist Fractures (2) · postintensive care syndrome (2) · Adrenal incidentaloma (1) · Adrenocortical Carcinoma (1) · Angina, Unstable (1)
Intubation, Intratracheal (2) · Ketanserin (2) · Absorptiometry, Photon (1) · Adalimumab (1) · Beds (1) · Blood Specimen Collection (1) · Carboplatin (1) · Cetuximab (1) · Clindamycin (1) · Clopidogrel (1) · Echocardiography, Transesophageal (1) · Etanercept (1) · Furosemide (1) · GLPG0634 (1) · Health Personnel (1)
Netherlands (59) · Germany (1) · Italy (1) · Lithuania (1) · Turkey (Türkiye) (1)
Matty Koopmans, MSc (6) · Christiaan Boerma, MD (5) · E.C. Boerma, MD-PhD (2) · Ewoud ter Avest, MD, PhD (2) · A Pranskunas, MD (1) · A.F. Muller, MD, PhD (1) · Aaltje Adema, dr. (1) · Adriaan Kooy, Dr. (1) · B. Havekes, MD, PhD (1) · Can Ince, Prof (1) · Carla M van Herpen, MD, PhD (1) · Christiaan Boerma (1) · Christiaan Boerma, Dr (1) · Christiaan Boerma, MD PhD (1)
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