34 recruiting, 30 completed, 21 unknown, 10 not yet recruiting. 36 Not applicable, 21 Phase 2, 7 Phase 3, 6 Phase 4, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Laparoscopic Hepatectomy Combined With Splenectomy on Hepatic Functional Reserve and Immune Function Liver Cirrhosis, HCC - Hepatocellular Carcinoma | Recruiting | Northern Jiangsu People's Hospital | 30 | 2026-08-02 | 2026-09-10 | |
| Ipsilateral Versus Bilateral Systematic Biopsy Combined With MRI/Ultrasound Cognitive Fusion Targeted Biopsy for Prostate Cancer Diagnosis MRI/US Cognitive Fusion Targeted Biopsy Plus Ipsilateral Systematic Biopsy, MRI/US Cognitive Fusion Targeted Biopsy Plus Bilateral Systematic Biopsy - Prostate Cancer | Not applicable | Recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 454 | 2026-07-20 | 2026-08-31 |
| Long-term Efficacy and Safety of LSD Versus TIPS for Cirrhotic Portal Hypertension Bleeding and Hypersplenism LSD, TIPS - Liver Cirrhosis | Not yet recruiting | Northern Jiangsu People's Hospital | 140 | 2026-06-01 | 2026-05-18 | |
| Effect of Laparoscopic Splenectomy on Lipid Profiles in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up) Cirrhosis, Splenectomy; Status | Not yet recruiting | Northern Jiangsu People's Hospital | 30 | 2026-05-01 | 2026-05-14 | |
| Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up) Cirrhosis, Liver, Splenectomy; Status | Not yet recruiting | Northern Jiangsu People's Hospital | 30 | 2026-05-01 | 2026-05-18 | |
| Effect of LSD on Lipid Profiles in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up) Cirrhosis, Liver, Splenectomy; Status | Not yet recruiting | Northern Jiangsu People's Hospital | 30 | 2026-05-01 | 2026-05-14 | |
| Effect of Laparoscopic Splenectomy on Renal Function in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up) Cirrhosis, Splenectomy; Status | Not yet recruiting | Northern Jiangsu People's Hospital | 30 | 2026-05-01 | 2026-05-18 | |
| Efficacy of Apixaban in the Treatment of Portal Vein Thrombosis Occurring More Than One Year After LS Apixaban 2.5 MG - Cirrhosis, Splenectomy | Not applicable | Recruiting | Northern Jiangsu People's Hospital | 20 | 2026-04-01 | 2026-03-31 |
| FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer Standard First-Line Therapy, FMT Combined with Standard First-Line Therapy - Unresectable Colorectal Cancer, Colorectal Cancer (Locally Advanced or Metastatic) | Phase 2 / Phase 3 | Not yet recruiting | Shanghai 10th People's Hospital | 220 | 2026-04-01 | 2026-04-03 |
| Efficacy of Apixaban in Treating Portal Vein Thrombosis Occurring More Than One Year After LSD Apixaban 2.5 MG - Cirrhosis, Splenectomy | Not applicable | Recruiting | Northern Jiangsu People's Hospital | 20 | 2026-04-01 | 2026-03-31 |
| Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection Vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection - Cirrhosis, Hypersplenism | Not applicable | Recruiting | Northern Jiangsu People's Hospital | 15 | 2026-03-25 | 2026-04-01 |
| Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock Hydrocortisone plus Fludrocortisone, Standard care - Septic Shock | Phase 4 | Recruiting | Northern Jiangsu People's Hospital | 336 | 2026-03-02 | 2026-03-04 |
| The Efficacy of Personalized Local Anesthetic Dosing Based on Ultrasound-Measured Nerve Cross-Sectional Area in Brachial Plexus Block: a Non-Inferiority Randomized Controlled Trial. CSA-based dosing of Ropivacaine, Experience-based dosing of Ropivacaine, Weight-based dosing of Ropivacaine - Upper Limb Surgery | Not applicable | Not yet recruiting | Northern Jiangsu People's Hospital | 300 | 2026-02-01 | 2026-01-20 |
| Correlation Between Advanced Glycation End Products and Gastric Motility Disorder in Diabetes Gastroparesis Diabetic Gastroparesis | Recruiting | Northern Jiangsu People's Hospital | 50 | 2026-01-07 | 2026-02-17 | |
| Efficacy and Safety of Icaritin Combined With mFOLFOX in Postoperative HCC With High-risk Recurrence Factors Icaritin Soft Capsules and mFOLFOX :Oxaliplatin,leucovorin calcium,5-fluorouracil - Hepatocellular Carcinoma (HCC) | Phase 2 | Recruiting | Northern Jiangsu People's Hospital | 30 | 2025-11-01 | 2026-01-13 |
| SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak SIS-reinforced anastomosis - Rectal Cancer | Phase 4 | Recruiting | Beijing Chao Yang Hospital | 966 | 2025-10-21 | 2026-06-17 |
| Laparoscopic Partial Splenectomy for Hypersplenism in Liver Cirrhosis Patients Laparoscopic Partial Splenectomy - Cirrhoses, Liver, Splenectomy; Status | Not applicable | Recruiting | Northern Jiangsu People's Hospital | 30 | 2025-09-24 | 2025-10-03 |
| Efcacy and Safety of Postoperative Adjuvant Hepatic Arterial Infusion Chemotherapy With mFOLFOX in Hepatocellular Carcinoma With High-risk Recurrence Factors mFOLFOX :Oxaliplatin,leucovorin calcium,5-fluorouracil - Hepatocellular Carcinoma (HCC) | Phase 2 | Recruiting | Northern Jiangsu People's Hospital | 30 | 2025-09-01 | 2026-01-13 |
| Effects of Positive End-Expiratory Pressure Levels on Lung Recruitment Duration and Hemodynamics After Alveolar Recruitment Maneuver: A Randomized Clinical Trial lung recruitment maneuvre; PEEP - Dynamic Lung Compliance, Alveolar Recruitment Maneuver | Not applicable | Completed | Northern Jiangsu People's Hospital | 101 | 2025-08-30 | 2026-03-24 |
| Tislelizumab Combined With Thoracic Radiotherapy as Neoadjuvant Therapy for Resectable NSCLC Tislelizumab, 3D-CRT/IMRT - Resectable NSCLC | Phase 2 | Recruiting | Northern Jiangsu People's Hospital | 20 | 2025-08-01 | 2026-01-09 |
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Fibrosis (19) · Hypertension, Portal (12) · Liver Cirrhosis (11) · Hypersplenism (7) · Carcinoma, Hepatocellular (6) · Stomach Neoplasms (5) · Colorectal Neoplasms (4) · Prostatic Neoplasms (4) · Rectal Neoplasms (4) · Shock, Septic (4) · Disease (3) · Recurrence (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Hypertension (2)
venetoclax (5) · Saline Solution (4) · apixaban (4) · dalpiciclib (4) · Azacitidine (3) · Hydrocortisone (3) · fluzoparib (3) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (2) · Cisplatin (2) · Dipyridamole (2) · Esketamine (2) · N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide (2) · Rituximab (2) · Sodium Chloride (2) · apatinib (2)
China (91)
Guo-Qing Jiang, MD (13) · Guo-Qing Jiang (3) · Qingquan Lyu, Master (3) · Daorong Wang, M.D., Professor (2) · Dou-Sheng Bai (2) · Dou-Sheng Bai, MD (2) · Dou-sheng Bai (2) · Ping Chen, MD (2) · Bao-Huan Zhou, MS (1) · Bimin Shi, PHD (1) · Bin Sun, PhD (1) · Dou-Sheng Bai Bai, MD (1) · Gu Yuxiang, PhD (1) · Haibo Qiu, MD (1) · Hong Liu (1)
PMID 25647058, PMID 25902890, PMID 26235391, PMID 28615145, PMID 31194613, PMID 31587835, PMID 32068572, PMID 33084588, PMID 33190629, PMID 34964875, PMID 35676457, PMID 35974310, PMID 36171582, PMID 36478144, PMID 36570501, PMID 36823150, PMID 38578352, PMID 39580964, PMID 39604913, PMID 40181528, PMID 40367062, PMID 40676300, PMID 40731293, PMID 41199560, PMID 41671463, PMID 42265606, PMID 42319125, PMID 42469432, PMID 42566007