Bacteremia: Clinical Trials

210 completed, 44 unknown, 32 terminated, 28 recruiting. 110 Not applicable, 41 Phase 4, 31 Phase 2, 28 Phase 3, 13 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	110	Completed 75, Unknown 14, Recruiting 10, Terminated 6, Active not recruiting 4, Not yet recruiting 1
Phase 4	41	Completed 20, Terminated 7, Unknown 6, Recruiting 5, Withdrawn 2, Active not recruiting 1
Phase 2	31	Completed 15, Terminated 6, Unknown 4, Withdrawn 4, Not yet recruiting 1, Recruiting 1
Phase 3	28	Completed 17, Terminated 6, Unknown 3, Recruiting 1, Withdrawn 1
Phase 1	13	Completed 12, Withdrawn 1
Early Phase 1	1	Completed 1

Follow Bacteremia: new trials by email Literature Review of Bacteremia trials Research Report on Bacteremia

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
THiamine for Recovery In Vulnerable Early-life Infections thiamine hydrochloride 100 mg, Placebo - Meningitis, Bacteremia	Phase 2	Not yet recruiting	Milton S. Hershey Medical Center	240	2026-12-01	2026-10-09
Cefepime/Enmetazobactam for Bacteremic Complicated Urinary Tract Infections Complicated Urinary Tract Infections, Antibiotic Resistance		Not yet recruiting	IRCCS Azienda Ospedaliero-Universitaria di Bologna	200	2026-10-15	2026-07-24
Microbiology Operations & Time Optimization in Sepsis laboratory infrastructure - Sepsis, Bloodstream Infection		Not yet recruiting	University Medicine Greifswald	1000	2026-10-01	2026-09-14
The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial Beta-lactam antibiotic with spectrum for Enterococcus faecalis, Cephalosporin - Aortic Valve Stenosis	Not applicable	Recruiting	Copenhagen University Hospital, Rigshospitalet	1986	2026-10-01	2026-10-05
Evaluation of Diagnostic Accuracy and Clinical Performance of the UllCORE Bloodstream Infection (BSI) Test UllCORE BSI Test - Blood Stream Infection, Blood Stream Infections		Recruiting	Deepull Diagnostics S.L.	1500	2026-09-21	2026-10-08
Oral Switch in Pediatric Bloodstream Infections Oral antibiotic therapy, Standard IV antibiotic therapy - Bloodstream Infection, Bacteremia Sepsis	Phase 4	Recruiting	Ulrikka Nygaard	150	2026-09-01	2026-10-19
Blood Culture Collection Strategies for Suspected Bloodstream Infection Standardized sequential blood culture collection - Bacteremia and Sepsis, Bloodstream Infection	Not applicable	Active not recruiting	Izola General Hospital	3000	2026-08-01	2026-08-07
Machine Learning Assisted Electrochemical Profiling to Provide Early Identification of Bloodstream Infections Pathogens Blood culture sampling - Bacteremia Sepsis	Not applicable	Recruiting	University Hospital, Grenoble	200	2026-07-13	2026-07-22
Antimicrobial Resistant Organism Decolonization After Microbiome Perturbation MET-2, Placebo - Gram-negative Bacteremia, Microbial Colonization	Phase 2	Withdrawn	University Health Network, Toronto		2026-07-01	2026-03-12
Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety Evaluation Efferon LPS, Toramyxin PMX 20R, Jafron HA 330 - Septic Shock	Not applicable	Not yet recruiting	Moscow Multidisciplinary Clinical Center "Kommunarka"	76	2026-06-25	2026-07-02
From Commensalism to Pathogenicity: Exploring the Pathophysiology of Bacteremia to Better Understand Enterococcus Faecalis Infective Endocarditis Microbiological sampling (swab collection) - Infective Endocarditis (IE)	Not applicable	Recruiting	University Hospital, Clermont-Ferrand	90	2026-04-17	2026-10-13
OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study AN69-polyethylenimine hemofilter (Oxiris®) used for continuous veno-venous hemofiltration (CVVH) - Sepsis, Septic Shock		Recruiting	Pauls Stradins Clinical University Hospital	29	2026-03-01	2026-02-19
Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia Beta-lactam monotherapy, Beta-lactam plus levofloxacin combination therapy - Bacteremia, Streptococcus Infection	Phase 4	Recruiting	Mahidol University	165	2026-01-08	2026-08-21
Clinical Efectiveness of a Multiplex PCR-Based Rapid Diagnostic Method in Bloodstream Infections Multiplex PCR-Based Rapid Diagnostic Test, Standard Microbiological Diagnostic Methods - Bloodstream Infections, Bacteremia and Sepsis		Recruiting	Istanbul Medipol University Hospital	300	2026-01-01	2026-02-13
Impact of Blood Cultures Drawn From Arterial Lines on the Incidence of Contamination, Detection of Bacteremia, and Blood Culture Volume Blood culture taken from an arterial catheter - Bacteremia		Recruiting	Meir Medical Center	1500	2026-01-01	2026-10-09
Febrile Infants Swedish Study Febrile Illness Acute, Meningitis, Bacterial		Recruiting	Region Skane	2000	2025-12-01	2026-04-02
Epidemiology of Antimicrobial-use and Antimicrobial-resistant Infections in Four Hospitals in Thailand Drug Resistance, Bacterial		Active not recruiting	University of Oxford	108000	2025-12-01	2026-08-14
Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function Short-Chain Fatty Acid Colon-Delivery Capsules, Placebo capsules, Lipopolysaccharide (LPS) - Endotoxemia, Inflammation	Not applicable	Recruiting	Universitaire Ziekenhuizen KU Leuven	56	2025-10-24	2026-07-20
Linezolid Plus Standard of Care Linezolid 600 mg, Placebo - Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)	Not applicable	Recruiting	University Hospital, Basel, Switzerland	606	2025-10-06	2026-07-13
Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols Scaling and Root Planing, antibiotic prophylaxis, 810nm Diode Laser - Periodontitis	Not applicable	Recruiting	National and Kapodistrian University of Athens	75	2025-08-25	2025-09-04

Showing 20 of 338. Sign in to see all of them.

Narrower conditions

Sepsis (94)  ·  Endotoxemia (80)  ·  Staphylococcal Infections (36)  ·  Inflammation (25)  ·  Infections (24)  ·  Shock, Septic (20)  ·  Bacterial Infections (17)  ·  Endocarditis (17)  ·  Pneumonia (13)  ·  Urinary Tract Infections (13)  ·  Fungemia (9)  ·  Gram-Positive Bacterial Infections (9)  ·  Catheter-Related Infections (8)  ·  Disease (7)

Broader conditions

Pathological Conditions, Signs and Symptoms (338)  ·  Pathologic Processes (337)  ·  Systemic Inflammatory Response Syndrome (334)  ·  Infections (314)  ·  Inflammation (313)  ·  Bacterial Infections and Mycoses (259)  ·  Sepsis (244)  ·  Bacterial Infections (242)  ·  Toxemia (80)  ·  Gram-Positive Bacterial Infections (39)  ·  Cardiovascular Diseases (30)  ·  Disease Attributes (27)  ·  Respiratory Tract Diseases (27)  ·  Urogenital Diseases (24)

Interventions

Daptomycin (17)  ·  Vancomycin (15)  ·  Endotoxins (11)  ·  Lipopolysaccharides (10)  ·  Cefazolin (6)  ·  Ethanol (6)  ·  Linezolid (6)  ·  Meropenem (6)  ·  Cloxacillin (5)  ·  Piperacillin, Tazobactam Drug Combination (5)  ·  Ceftaroline (4)  ·  Heparin (4)  ·  Oxacillin (4)  ·  Whey (4)  ·  endotoxin, Escherichia coli (4)

Sponsors

Radboud University Medical Center (21)  ·  Copenhagen University Hospital, Rigshospitalet (7)  ·  Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (7)  ·  Assistance Publique - Hôpitaux de Paris (5)  ·  Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (5)  ·  University of Aarhus (5)  ·  Central Hospital, Nancy, France (4)  ·  Laval University (4)  ·  Ohio State University (4)  ·  Pfizer (4)  ·  Spectral Diagnostics (US) Inc. (4)  ·  University of Pittsburgh (4)  ·  Duke University (3)  ·  Fondation Hôpital Saint-Joseph (3)  ·  Hasselt University (3)

Countries

United States (82)  ·  France (35)  ·  Spain (28)  ·  Netherlands (24)  ·  Canada (19)  ·  Denmark (18)  ·  Italy (15)  ·  Germany (14)  ·  Israel (14)  ·  Austria (11)  ·  Greece (11)  ·  Turkey (Türkiye) (9)  ·  Australia (8)  ·  South Korea (8)  ·  Taiwan (8)

Top investigators

Niels Moeller, Professor (5)  ·  Peter Pickkers, MD, PhD (5)  ·  Anne Sofie Andreasen, MD (3)  ·  Inge C Gyssens, MD, PhD (3)  ·  Nick Daneman, MD (3)  ·  Richard Bruno, PhD, RD (3)  ·  Amanda Wilkins, MBBS (2)  ·  Bernd Jilma, MD (2)  ·  David L Paterson, MD (2)  ·  Karen Fusaro (2)  ·  Mical Paul, MD (2)  ·  Noa Eliakim-Raz, MD (2)

Results publications

PMID 40517600, PMID 11358467, PMID 12435223, PMID 14638511, PMID 14668610, PMID 15004058, PMID 15757584, PMID 15814879, PMID 15966875, PMID 16131307, PMID 16155063, PMID 16216646, PMID 16420547, PMID 16424713, PMID 16641463, PMID 16864730, PMID 16914701, PMID 16965625, PMID 17353249, PMID 17403700, PMID 17538551, PMID 17954801, PMID 18349379, PMID 18418495, PMID 18433844, PMID 19026506, PMID 19191635, PMID 19318651, PMID 19489710, PMID 19686276, PMID 19713086, PMID 19797553, PMID 19845694, PMID 19882553, PMID 20444270, PMID 20462352, PMID 20520776, PMID 20705364, PMID 21211004, PMID 21248153, PMID 21282693, PMID 21516036, PMID 21926570, PMID 21931634, PMID 22005999, PMID 22129171, PMID 22162470, PMID 22169408, PMID 22178010, PMID 22340450

NIH funding

2005 (2), 2014 (2), 2016 (2), 2023 (2), 2015 (1), 2019 (1), 2025 (1), 5UM1AI104681-12 (1), KL2TR000136 (1), R01AI116993 (1), R01DE013559 (1), R01HD122957 (1), R21HD088005 (1), UM1AI104681 (1)