Hyperglycemia: Clinical Trials

976 completed, 196 unknown, 117 recruiting, 75 terminated. 854 Not applicable, 138 Phase 4, 126 Phase 2, 91 Phase 3, 69 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	854	Completed 551, Unknown 112, Recruiting 70, Terminated 33, Active not recruiting 32, Not yet recruiting 30, Withdrawn 21, Enrolling by invitation 4, Suspended 1
Phase 4	138	Completed 93, Unknown 20, Terminated 12, Recruiting 6, Active not recruiting 2, Not yet recruiting 2, Withdrawn 2, Enrolling by invitation 1
Phase 2	126	Completed 84, Unknown 14, Terminated 9, Recruiting 7, Withdrawn 6, Active not recruiting 4, Enrolling by invitation 1, Suspended 1
Phase 3	91	Completed 72, Unknown 8, Terminated 7, Active not recruiting 2, Withdrawn 2
Phase 1	69	Completed 44, Terminated 10, Recruiting 5, Unknown 4, Withdrawn 4, Suspended 2
Early Phase 1	18	Completed 13, Recruiting 3, Not yet recruiting 1, Terminated 1

Follow Hyperglycemia: new trials by email Literature Review of Hyperglycemia trials Research Report on Hyperglycemia

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance Vigabatrin Pill, Placebo oral tablet - Hyperinsulinism, Insulin Resistance	Phase 2	Withdrawn	University of Arizona		2030-04-15	2025-07-30
Efficacy of the pA1c®HI Postbiotic in Metabolic Regulation in Healthy Individuals With Hyperglycemia Postbiotic - Hyperglycemias, Prediabetes	Early Phase 1	Not yet recruiting	Genbioma Aplicaciones SL	100	2027-01-07	2026-10-29
The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity Continuous Glucose Monitoring (CGM) - Pre Diabetic, Obesity & Overweight	Not applicable	Recruiting	University of Primorska	34	2026-12-15	2026-10-22
The BRIGHT Study (Device Name: HALO System) The HALO System - Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2	Not applicable	Not yet recruiting	Indigo Diabetes NV	12	2026-12-01	2026-08-04
Unmasking Diabetes in Dialysis With Continuous Glucose Monitoring Continuous Glucose Monitoring (CGM) - End Stage Kidney Disease (ESKD), Hyperglycaemia		Not yet recruiting	Emory University	180	2026-12-01	2026-10-27
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults Obesity, Diabetes		Not yet recruiting	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	1000	2026-11-04	2026-10-30
Whole-Food Magnesium for Mental and Cardiometabolic Health Low-Dose Whole-Food-Based Magnesium Supplement, Moderate-Dose Whole-Food-Based Magnesium Supplement, Placebo - Elevated Blood Glucose	Not applicable	Not yet recruiting	George Mason University	45	2026-11-01	2026-10-08
Effects of Mango on Insulin Sensitivity in Prediabetes Mango juice, Control Beverage - Pre Diabetes	Not applicable	Not yet recruiting	Clinical Nutrition Research Center, Illinois Institute of Technology	64	2026-10-28	2026-10-29
Stress Hyperglycemia Ratio and Glucose Variability in Critically Ill Patients Critical Illness, Hyperglycemia		Not yet recruiting	Assiut University	75	2026-10-20	2026-10-23
Multimodal Risk Factor Graph Mapping, Metabolic Subtyping, and Digital Intelligent Chronic Disease Management for Prediabetes: An Integrated Cohort and Case-Control Clinical Study Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)		Not yet recruiting	Nanjing Medical University	30000	2026-10-08	2026-10-02
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults Fish Oil, Corn oil control - Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)	Phase 2	Recruiting	May Faraj, PDt, PhD	84	2026-10-05	2026-10-08
Diabetes Prevention AI: Enhancing Prevention Strategies Using Personalized Nutrition and Fitness Coaching for the Next Generation AI-Powered Diabetes Prevention Chatbot - Pre Diabetes, Type2 Diabetes	Not applicable	Not yet recruiting	Emory University	30	2026-10-01	2026-09-17
Hypothalamic GLP-1 Response in Healthy Weight and Obesity Gastric glucose, GLP-1(7-36)NH2, Exendin(9-39)NH2 - Obesity, Normal Weight	Not applicable	Not yet recruiting	University of Copenhagen	60	2026-10-01	2026-10-02
Studies of Blood Glucose and the Microbiome in Tumors and Cysts of the Pancreas Pancreatic Neoplasms, Pancreatic Cysts		Not yet recruiting	Umeå University	100	2026-10-01	2026-09-25
Prognostic Value of Stress Hyperglycemia Ratio in Critically Ill Patients Critical Illness, Hyperglycemia		Not yet recruiting	Assiut University	230	2026-10-01	2026-10-02
Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery Maltodextrin carbohydrate drink, Sugar water - Respiratory Aspiration, Hyperglycemia	Not applicable	Recruiting	Udayana University	62	2026-09-27	2026-10-14
Real-time Engagement for Learning to Effectively Control Type 2 Diabetes Focused App Prompt, No App Prompt - Diabetes Mellitus, Type 2, Lifestyle	Not applicable	Recruiting	University of Pittsburgh	100	2026-09-20	2026-10-07
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health Quercetin (dietary supplement), Coenzyme Q10, Rice Flour - Healthy Aging, Inflammaging	Not applicable	Recruiting	Applied Science & Performance Institute	60	2026-09-18	2026-09-17
CGM Experience, Preferences & Blood Glucose Parameters CGM - Diabete Mellitus, Type2diabetes		Not yet recruiting	Getz Pharma	75	2026-09-10	2026-05-26
The Effect of Nutrient Sequencing in Healthy Adults Finger Prick- Blood Glucose, Whole Blood Draw, Diet History Questionnaire - Pre Diabetes	Not applicable	Active not recruiting	Cornell University	40	2026-09-01	2026-10-14

Showing 20 of 1519. Sign in to see all of them.

Narrower conditions

Glucose Intolerance (786)  ·  Diabetes Mellitus (327)  ·  Diabetes Mellitus, Type 2 (304)  ·  Insulin Resistance (252)  ·  Obesity (227)  ·  Prediabetic State (136)  ·  Hypoglycemia (112)  ·  Metabolic Syndrome (100)  ·  Hypertension (87)  ·  Overweight (85)  ·  Diabetes Mellitus, Type 1 (76)  ·  Motor Activity (59)  ·  Cardiovascular Diseases (42)  ·  Dyslipidemias (42)

Broader conditions

Nutritional and Metabolic Diseases (1518)  ·  Metabolic Diseases (1498)  ·  Glucose Metabolism Disorders (1482)  ·  Endocrine System Diseases (740)  ·  Pathological Conditions, Signs and Symptoms (444)  ·  Diabetes Mellitus (406)  ·  Hyperinsulinism (320)  ·  Signs and Symptoms (314)  ·  Body Weight (272)  ·  Nutrition Disorders (271)  ·  Overnutrition (263)  ·  Overweight (180)  ·  Pathologic Processes (154)  ·  Cardiovascular Diseases (146)

Interventions

Metformin (57)  ·  Insulin (52)  ·  Exercise (37)  ·  Insulin Glargine (33)  ·  Continuous Glucose Monitoring (23)  ·  Insulin Aspart (22)  ·  Pioglitazone (22)  ·  Diet (19)  ·  Sitagliptin Phosphate (19)  ·  Exenatide (18)  ·  Glucose (18)  ·  Glucose Tolerance Test (16)  ·  Standard of Care (15)  ·  dapagliflozin (14)  ·  Insulin Lispro (13)

Sponsors

Emory University (21)  ·  Maastricht University Medical Center (21)  ·  Johns Hopkins University (15)  ·  Yale University (15)  ·  Ohio State University (13)  ·  Mayo Clinic (11)  ·  Sanofi (11)  ·  Stanford University (10)  ·  Washington University School of Medicine (10)  ·  Clinical Nutrition Research Center, Illinois Institute of Technology (9)  ·  National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (9)  ·  Singapore Institute of Food and Biotechnology Innovation (9)  ·  University of Guadalajara (9)  ·  Duke University (8)  ·  Indiana University (8)

Countries

United States (646)  ·  Canada (81)  ·  United Kingdom (66)  ·  China (51)  ·  Italy (45)  ·  Netherlands (44)  ·  Germany (43)  ·  Denmark (40)  ·  Mexico (39)  ·  France (35)  ·  Spain (33)  ·  Sweden (29)  ·  South Korea (27)  ·  Taiwan (26)  ·  Singapore (24)

Top investigators

Guillermo Umpierrez, MD (10)  ·  Rubina Heptulla, MD (5)  ·  Gary Williamson (4)  ·  Eyal Dassau, PhD (3)  ·  Hassan S Dashti, Ph.D., R.D. (3)  ·  Hilda Nyambe (3)  ·  Jose A. Luchsinger, MD (3)  ·  Kathleen M Dungan, MD (3)  ·  Pam Taub, MD (3)  ·  PierMarco Piatti, MD (3)  ·  Richard Bruno, PhD, RD (3)  ·  Robert R Henry, MD (3)

Results publications

PMID 37526194, PMID 32803882, PMID 33210751, PMID 29021286, PMID 39963952, PMID 11889147, PMID 15793249, PMID 17513708, PMID 19318384, PMID 23435159, PMID 23451166, PMID 23703580, PMID 26590418, PMID 27267268, PMID 27319011, PMID 31231311, PMID 31334795, PMID 31465427, PMID 31956422, PMID 32475838, PMID 33829034, PMID 34923911, PMID 35130909, PMID 36469736, PMID 38770818, PMID 10371488, PMID 10546015, PMID 10598830, PMID 10711923, PMID 10889804, PMID 11162047, PMID 11219223, PMID 11333990, PMID 11512567, PMID 11527163, PMID 11576521, PMID 11743518, PMID 11794168, PMID 11816692, PMID 11832527, PMID 12065146, PMID 12145174, PMID 12485966, PMID 12630816, PMID 12829659, PMID 12867348, PMID 12876091, PMID 12933380, PMID 12948306, PMID 14514637

NIH funding

2019 (5), OT2HL158287 (4), 2009 (3), 2015 (3), 2018 (3), 2008 (2), 2014 (2), 2016 (2), 2017 (2), R01AG050440 (2), R01AT008310 (2), R01DK111038 (2), R01DK137803 (2), 2005 (1), 2025 (1)