239 completed, 50 unknown, 38 recruiting, 27 terminated. 166 Not applicable, 54 Phase 3, 54 Phase 4, 52 Phase 2, 11 Phase 1.
Follow Psychomotor Disorders: new trials by email Literature Review of Psychomotor Disorders trials Research Report on Psychomotor Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems | Phase 1 / Phase 2 | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 70 | 2027-03-01 | 2026-05-04 |
| Deep Brain Stimulation + Therapy for Stroke Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol - Stroke, Dysarthria | Not applicable | Not yet recruiting | Pirondini, Elvira, PhD | 15 | 2027-01-01 | 2026-09-30 |
| Virtual Reality to Advance Dementia Care and Quality of Life Supervised Virtual Reality Sessions - Dementia, Agitation | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 10 | 2026-12-01 | 2026-10-26 |
| Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome SRX246, Placebo - Aggressive Behavior in Fragile X Syndome | Phase 2 | Not yet recruiting | Azevan Pharmaceuticals | 80 | 2026-12-01 | 2026-10-30 |
| Role of Omega-DEK in Childhood Apraxia of Speech Omega-DEK, L-carnitine, Placebo - Childhood Apraxia of Speech, Verbal Apraxia | Phase 2 | Not yet recruiting | Claudia R. Morris | 34 | 2026-11-01 | 2026-07-29 |
| Ideomotor Apraxia and Robotic Gait Rehabilitation Outcomes After Stroke Stroke, Ideomotor Apraxia | Recruiting | Izmir City Hospital | 60 | 2026-10-30 | 2026-11-03 | |
| Post-Stroke Apraxia, Motor Function, Balance, and Gait Standardized clinical assessment - Stroke, Ideomotor Apraxia | Recruiting | Izmir City Hospital | 54 | 2026-10-15 | 2026-11-03 | |
| Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial Esketamine combined with dexmedetomidine, Dexmedetomidine - Dexmedetomidine, Ketamine | Phase 4 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 356 | 2026-09-28 | 2026-09-03 |
| Motor-based Intervention for Childhood Apraxia of Speech: DTTC-Connect Dynamic Temporal and Tactile Cueing - Connect (DTTC-Connect) - Childhood Apraxia of Speech | Not applicable | Recruiting | New York University | 68 | 2026-09-15 | 2026-09-18 |
| Wearable Sensor Toolkit for Infant Motor Development Motor Delay, Infant Development | Not yet recruiting | Shirley Ryan AbilityLab | 90 | 2026-09-01 | 2026-10-08 | |
| Clinical Trial of Peer Support in the ED (PCORI) Peer-Support Enhanced Agitation Code Team (PACT) - Psychomotor Agitation, Behavioral Disorder | Not applicable | Not yet recruiting | Yale University | 57870 | 2026-07-01 | 2026-05-18 |
| Speech Therapy for Children With Rare Genetic Conditions and Childhood Apraxia of Speech Rapid Syllable Transition Treatment, Dynamic Temporal and Tactile Cueing - Childhood Apraxia of Speech, Genetic Condition | Not applicable | Recruiting | Murdoch Childrens Research Institute | 20 | 2026-07-01 | 2026-09-11 |
| Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients Virtual reality (VR) therapy - Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients | Not applicable | Completed | Milton S. Hershey Medical Center | 20 | 2026-06-02 | 2026-10-23 |
| Synchronous vs. Asynchronous Telerehabilitation for High-Risk Infants Synchronous Telerehabilitation Group, Asynchronous Telerehabilitation Group - Risky Baby, Premature Birth of Newborn | Not applicable | Not yet recruiting | Biruni University | 48 | 2026-05-04 | 2026-03-30 |
| Effect of Daily Screen Time on Postoperative Emergence Delirium in Children Aged 2-11 Years Daily Screen Exposure Duration - Agitation, Postoperative Agitation | Recruiting | Kanuni Sultan Suleyman Training and Research Hospital | 288 | 2026-05-01 | 2026-08-05 | |
| Activation-Socialization Intervention Program for Seniors Activation and Socialization Intervention Program - Healthy | Not applicable | Enrolling by invitation | Diana Ďuricová | 200 | 2026-04-20 | 2026-04-09 |
| ED-TREAT (Early Detection and Treatment to Reduce Events With Agitation Tool) Compared to Usual Care ED-TREAT - Psychomotor Agitation, Behavioral Disorder | Not applicable | Suspended | Yale University | 26 | 2026-04-01 | 2026-03-12 |
| Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in Children Rapid Syllable Transition Treatment (ReST) - Childhood Apraxia of Speech | Not applicable | Active not recruiting | Aline Mara de Oliveira | 20 | 2026-04-01 | 2026-06-09 |
| Feasibility and Preliminary Effects of a Therapeutic Approach Using Ultrasound Visual Biofeedback in Children With AFI: a Pilot Randomized Clinical Trial. Ultrasound Visual Feedback, Waitlist - Childhood Apraxia of Speech, Speech Sound Disorders | Not applicable | Recruiting | Aline Mara de Oliveira | 20 | 2026-04-01 | 2026-10-27 |
| Complex Rehabilitation Technology Enabled Physical Activity for Children With Motor Delays Via Telehealth in Natural Environments Stander Use - Cerebral Palsy (CP), Motor Disability | Not applicable | Recruiting | Ohio State University | 20 | 2026-02-19 | 2026-05-07 |
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Psychomotor Agitation (281) · Alzheimer Disease (76) · Dementia (75) · Apraxias (65) · Delirium (30) · Schizophrenia (25) · Pain (23) · Stroke (22) · Anxiety Disorders (21) · Psychotic Disorders (21) · Aggression (20) · Aphasia (18) · Depression (15) · Emergence Delirium (14)
Neurobehavioral Manifestations (405) · Neurologic Manifestations (405) · Pathological Conditions, Signs and Symptoms (405) · Signs and Symptoms (405) · Nervous System Diseases (402) · Behavior (291) · Dyskinesias (283) · Behavioral Symptoms (279) · Aberrant Motor Behavior in Dementia (278) · Mental Disorders (251) · Central Nervous System Diseases (160) · Brain Diseases (159) · Neurocognitive Disorders (159) · Neurodegenerative Diseases (85)
Dexmedetomidine (37) · Haloperidol (17) · Loxapine (10) · Midazolam (10) · Olanzapine (10) · Saline Solution (10) · Sodium Chloride (10) · Risperidone (9) · Standard of Care (8) · Quetiapine Fumarate (7) · Ketamine (6) · ziprasidone (6) · Dronabinol (5) · Lorazepam (5) · Music Therapy (5)
BioXcel Therapeutics Inc (12) · Otsuka Pharmaceutical Development & Commercialization, Inc. (10) · Assistance Publique - Hôpitaux de Paris (6) · VA Office of Research and Development (6) · Axsome Therapeutics, Inc. (5) · Centre for Addiction and Mental Health (5) · Hennepin Healthcare Research Institute (5) · Mayo Clinic (5) · Alexza Pharmaceuticals, Inc. (4) · Johns Hopkins University (4) · Ohio State University (4) · University Hospital, Angers (4) · University Hospital, Clermont-Ferrand (4) · Ain Shams University (3) · Emory University (3)
United States (184) · France (36) · Canada (30) · Turkey (Türkiye) (21) · China (18) · Spain (16) · United Kingdom (15) · Egypt (13) · Germany (12) · Italy (10) · South Korea (9) · Brazil (8) · Norway (8) · Poland (8) · Australia (7)
BioXcel MM, MD (8) · BioXcel MM (3) · Julie L Wambaugh, PhD (3) · Arun Jayaraman, PT, PhD (2) · Aylin Dikici, MD (2) · Constantine Lyketsos, MD, MHS (2) · Daphne Sze Ki Cheung, PhD (2) · Jacobo Mintzer, MD (2) · Jennifer Felger, PhD (2) · Lauren Klein, MD (2) · Lon Schneider, MD (2) · Nathan Herrmann, MD (2)
PMID 40681915, PMID 41533472, PMID 41961243, PMID 39108660, PMID 41591746, PMID 23245705, PMID 23422376, PMID 24035670, PMID 29163985, PMID 31708380, PMID 34532852, PMID 35703367, PMID 36002761, PMID 40847656, PMID 41439450, PMID 41689409, PMID 42052145, PMID 42502037, PMID 10692189, PMID 11001602, PMID 11087767, PMID 11133600, PMID 11442853, PMID 11473855, PMID 11604980, PMID 12040306, PMID 15114210, PMID 15840076, PMID 16247923, PMID 16677266, PMID 16879517, PMID 17035647, PMID 17326118, PMID 17416907, PMID 17984395, PMID 18519523, PMID 18676556, PMID 19369318, PMID 19454032, PMID 19700947, PMID 19709377, PMID 19901244, PMID 20006719, PMID 20214847, PMID 20418301, PMID 20492042, PMID 20492047, PMID 20497353, PMID 20528148, PMID 20621273
2023 (3), 2016 (2), 2017 (2), 1RC2AG036535 (1), 1RF1AG050967-01A1 (1), 2005 (1), 2008 (1), 2009 (1), 2018 (1), 2025 (1), K23MH126366 (1), N01MH090001 (1), N01MH90001 (1), P30AG073105 (1), P50AG005136 (1)