97 completed, 20 terminated, 8 unknown, 3 withdrawn. 52 Phase 4, 36 Phase 3, 17 Phase 2, 8 Not applicable, 6 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lumateperone for the Improvement of Apathy in Patients With Psychotic Symptoms. Lumateperone 42 mg, Risperidone 2 mg - Apathy, Schizophrenia | Phase 3 | Recruiting | Louisiana State University Health Sciences Center Shreveport | 80 | 2024-06-01 | 2024-07-01 |
| An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine Clozapine, Antipsychotics,Other (non-Clozapine) - Treatment-resistant Schizophrenia | Phase 4 | Terminated | Ohio State University | 5 | 2023-08-16 | 2026-02-25 |
| Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building Risperidone, Aripiprazole, Ziprasidone - Schizophrenia | Phase 4 | Unknown | Shanghai Mental Health Center | 350 | 2021-05-01 | 2020-08-26 |
| Reducing the Abuse of Opioids in Drug Users Oxycodone/Placebo, Oxycodone/Risperidone, Oxycodone/Ziprasidone - Opioid Abuse, Unspecified, Opioid Dependence | Early Phase 1 | Terminated | The University of Texas Health Science Center at San Antonio | 3 | 2019-04-01 | 2022-02-15 |
| Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder Ziprasidone, Placebo - Bipolar Disorder | Phase 3 | Terminated | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 23 | 2018-12-21 | 2021-06-16 |
| A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication ASP4345, placebo, risperidone - Schizophrenia | Phase 2 | Completed | Astellas Pharma Global Development, Inc. | 233 | 2018-07-13 | 2024-11-12 |
| Gene-by-Stress Interactions in Intervention Studies Significance Ziprasidone, Lorcaserin, Placebo Oral Tablet - Cardiovascular Diseases | Phase 1 | Terminated | Duke University | 7 | 2018-05-24 | 2020-02-17 |
| Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia Ziprasidone, Olanzapine, Placebo Comparator - Schizophrenia | Phase 1 | Active not recruiting | University of Arizona | 24 | 2017-11-20 | 2026-07-08 |
| Reducing the Abuse Liability of Prescription Opioids Risperidone, Ziprasidone, Oxycodone - Addiction | Early Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 15 | 2017-06-16 | 2020-10-14 |
| Olanzapine, Haloperidol, Ziprasidone, Midazolam for Acute Undifferentiated Agitation Haloperidol Injection, Ziprasidone Injection, OLANZapine Injection - Agitation,Psychomotor | Completed | Hennepin Healthcare Research Institute | 737 | 2017-06-15 | 2018-03-16 | |
| The Efficacy And Safety Of Intramuscular Ziprasidone For Three Days In Patients With Psychotic Agitation Ziprasidone - Schizophrenia | Phase 4 | Unknown | Yang Fude | 1000 | 2016-10-01 | 2016-10-18 |
| Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies Lithium Carbonate, Lamotrigine, Valproic Acid - Bipolar Disorder | Terminated | University of New Mexico | 1037352 | 2016-09-01 | 2024-03-12 | |
| The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients Atypical Antipsychotic, atypical antipsychotic combined with MECT - Schizophrenia, Micrognathia | Unknown | Dalian Seventh People's Hospital | 30 | 2016-06-01 | 2020-01-30 | |
| Family Intervention in Recent Onset Schizophrenia Treatment (FIRST) Caregiver psycho-education and skills training, Caregiver support available at the study site, Paliperidone palmitate - Schizophrenia | Completed | Janssen Scientific Affairs, LLC | 296 | 2015-07-24 | 2019-01-23 | |
| Outcomes of Antipsychotic Medication Used in the Emergency Department Adasuve, Alternative medications - Agitation,Psychomotor | Completed | Wake Forest University Health Sciences | 93 | 2015-04-01 | 2024-10-04 | |
| Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients Olanzapine, Amisulpride, Risperidone - Schizophrenia, Schizophrenia and Disorders With Psychotic Features | Phase 4 | Completed | Technical University of Munich | 21 | 2015-02-01 | 2018-10-11 |
| Pharmacovigilance in Gerontopsychiatric Patients Phenobarbital, Phenytoin, Carbamazepine - Dementia, Depression | Phase 3 | Terminated | Hannover Medical School | 407 | 2015-01-01 | 2018-02-28 |
| Treatment Study Comparing Aripiprazole Once Monthly With Standard of Care Medication in Outpatients With Schizophrenia Aripiprazole Once-Monthly, Oral Antipsychotic (i.e. aripiprazole, risperidone, lurasidone, quetiapine, olanzapine, ziprasidone, etc) - Schizophrenia | Phase 4 | Unknown | Matt Byerly | 200 | 2014-12-01 | 2015-06-08 |
| Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder placebo oral capsules, ziprasidone oral capsules - Bipolar Disorder | Phase 3 | Terminated | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 171 | 2014-05-23 | 2021-06-16 |
| Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania Lithium, Valproate, Oxcarbazepine - Bipolar Disorder | Phase 4 | Unknown | Guiyun Xu | 120 | 2013-09-01 | 2015-03-17 |
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Schizophrenia (72) · Psychotic Disorders (37) · Bipolar Disorder (35) · Depression (6) · Metabolic Syndrome (6) · Psychomotor Agitation (6) · Depressive Disorder, Major (5) · Diabetes Mellitus (5) · Anxiety Disorders (4) · Mania (4) · Cognition Disorders (3) · Delirium (3) · Diabetes Mellitus, Type 2 (3) · Insulin Resistance (3) · Mental Disorders (3)
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (40) · Massachusetts General Hospital (4) · Duke University (3) · Fundación Marques de Valdecilla (3) · Northwell Health (3) · The University of Texas Health Science Center at San Antonio (3) · Washington University School of Medicine (3) · Dr. Reddy's Laboratories Limited (2) · Medical University of Vienna (2) · Tufts Medical Center (2) · University of Sao Paulo (2) · Astellas Pharma Global Development, Inc. (1) · Baylor College of Medicine (1) · Beijing HuiLongGuan Hospital (1) · Birte Glenthoj (1)
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Benedicto Crespo-Facorro, Professor (3) · Antonio R. Pizarro, MD (2) · George I Papakostas, M.D. (2) · John W Newcomer, MD (2) · Linmarie Sikich, MD (2) · Adel Elsheshai, MD (1) · Ahmad Hatim Sulaiman, MBBS,MPM (1) · Ameet Nagpal, MD (1) · Amelia Gallitano, MD,PhD (1) · Andrew Winokur, M.D. (1) · Anusha Baskaran, BScH (1) · Ashwin Patkar, MD (1) · Birte Glenthoj, MD, DMSc. (1)
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K23MH074540 (1), N01MH090001 (1), N01MH90001 (1), P01HL036587 (1), R01MH059312 (1), R01MH060845 (1), R01MH063985 (1), R01MH080270 (1), R34MH077849 (1), U01MH070007 (1), U01MH070008 (1), U01MH070009 (1), U01MH070010 (1), U01MH070011 (1), U01MH070012 (1)