14 completed, 10 recruiting, 7 unknown, 2 active not recruiting. 39 Phase 3, 8 Phase 2.
Follow Pain Management: new trials by email Literature Review of Pain Management trials Research Report on Pain Management
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Analgesic Efficacy of the Biased μ-Opioid Receptor Agonist Tegileridine for Post-Operative Analgesia in Patients Undergoing Bariatric Surgery Tegileridine (tegileridine fumarate injection, IV), Sufentanil - Pain Management, Overweight , Obesity | Phase 3 | Recruiting | The First Hospital of Jilin University | 148 | 2026-10-28 | 2026-11-03 |
| Suzetrigine in TKA Placebo, Suzetrigine - Total Knee Arthroplasty (TKA), Total Knee Arthroplasty \(TKA\) | Phase 3 | Recruiting | Hospital for Special Surgery, New York | 148 | 2026-10-15 | 2026-10-13 |
| Methoxyflurane Versus Usual Care for Non-Traumatic Pain in Emergency Departments Analgesic management with Methoxyflurane as first-line treatment, Pain treatment according to the usual analgesic management protocol of the emergency department of the participating center. - Pain Management | Phase 3 | Not yet recruiting | University Hospital, Tours | 164 | 2026-09-16 | 2026-08-03 |
| Influence of Superficial Parasternal Intercostal Plane Block on Internal Thoracic Artery Caliber to Facilitate Surgical Harvesting in CABG Bupivacaine - Pain Management, Parasternal Block | Phase 3 | Recruiting | Ain Shams University | 50 | 2026-07-01 | 2026-10-28 |
| Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients oral ketamine, oxycodone - Pain Management | Phase 2 / Phase 3 | Not yet recruiting | Albany Medical College | 60 | 2026-06-24 | 2026-06-26 |
| Safinamide vs Placebo for Pain in Patients With Parkinson's Disease and Motor Fluctuations Safinamide, Placebo - PARKINSON DISEASE (Disorder), Pain | Phase 3 | Recruiting | Universita di Verona | 60 | 2026-04-28 | 2026-08-13 |
| Opioid-Sparing Joint Replacement Placebo, Oxycodone 5 mg, Multimodal Non-Opioid Analgesia - Pain Management, Opioid Consumption | Phase 3 | Recruiting | Emory University | 120 | 2026-03-19 | 2026-04-17 |
| Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip Surgeries Bupivacaine - Pain Management | Phase 3 | Recruiting | Benha University | 90 | 2026-03-15 | 2026-10-16 |
| R.E.C.K vs Exparel in Robotic Nephrectomy Ropivacaine HCL, Exparel, Epinephrine - Renal Carcinoma, Nephrectomy / Methods | Phase 3 | Recruiting | Wake Forest University Health Sciences | 170 | 2025-11-14 | 2026-07-13 |
| Suzetrigine in Total Hip Arthroplasty Suzetrigine, Placebo - Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\) | Phase 3 | Recruiting | Hospital for Special Surgery, New York | 210 | 2025-11-03 | 2026-07-30 |
| Virtual Reality for Pain and Anxiety Relief During Peripheral Angioplasty Virtual Reality, dexketoprofen + midazolam - Peripheral Angioplasty, Pain Management | Phase 2 / Phase 3 | Completed | Kastamonu University | 52 | 2025-08-01 | 2025-11-19 |
| Ketorolac at Lower Doses for Analgesic Pain Control in ICU: A Pilot Feasibility Study Ketorolac, Placebo - Pain Management | Phase 3 | Recruiting | University of Alberta | 30 | 2025-06-23 | 2026-09-28 |
| Management of Moderate to Severe Monotraumatic Pain With Sublingual Sufentanil in an Emergency Situation. sufentanil sublingual 30 mcg tablet, Standard of Care (SOC) - Pain Management | Phase 3 | Recruiting | University Hospital, Clermont-Ferrand | 300 | 2025-04-22 | 2026-04-28 |
| The Effect of High-thoracic Erector Spinae Plane Block on Postoperative Pain and Diaphragmatic Function in Posterior Cervical Spine Surgery Erector spina plane block (ESP), Bupivacain (preoperative) - Cervical Spine Surgery, Pain Management | Phase 3 | Completed | Benha University | 50 | 2025-01-01 | 2026-09-01 |
| Analgesic Effects of Intranasal Diclofenac Sodium, Ibuprofen, and Paracetamol in Pediatric Tonsillectomy Cases Intravenous paracetamol, Intranasal Paracetamol, Intranasal Diclofenac Sodium - Tonsil Disease, Pain Management | Phase 3 | Completed | Bezmialem Vakif University | 60 | 2024-12-15 | 2025-02-28 |
| Dexmedetomidine in Sonographic Guided Erector Spinae Plane Block Dexmedetomidine - Pain Management | Phase 2 / Phase 3 | Completed | Assiut University | 90 | 2024-10-01 | 2026-10-30 |
| Efficacy and Safety of Etoricoxib+Diacerein in Osteoarthritis. Etoricoxib 90 mg + diacerein 50 mg, Meloxicam 15 mg + diacerein 50 mg - Pain Management, Osteoarthritis | Phase 3 | Completed | Laboratorios Liomont | 123 | 2024-05-24 | 2026-04-29 |
| Efficacy of Liposomal Bupivacaine Post Septorhinoplasty Liposomal Bupivacaine, 0.25% bupivacaine with 1:200,000 epinephrine, Placebo - Saline solution - Rhinoplasty, Pain Management | Phase 3 | Enrolling by invitation | Jessyka Lighthall | 72 | 2024-02-05 | 2026-04-03 |
| Dexmedetomidine in Postoperative Analgesia Dexmedetomidine - Pain Management | Phase 2 / Phase 3 | Enrolling by invitation | New Valley University | 100 | 2023-08-01 | 2026-05-07 |
| Pain Management in Pediatric Adenotonsillectomy Tramadol 5%, Lidocaine 2% - Pain Management | Phase 3 | Unknown | Al-Azhar University | 80 | 2023-08-01 | 2023-07-11 |
Showing 20 of 39. Sign in to see all of them.
Agnosia (39) · Pain (8) · Osteoarthritis (2) · Acute Pain (1) · Anemia, Sickle Cell (1) · Carcinoma, Renal Cell (1) · Emergencies (1) · Liver Neoplasms (1) · Obesity (1) · Osteoarthritis, Knee (1) · Overweight (1) · Pain, Postoperative (1) · Parkinson Disease (1) · Prostatic Neoplasms (1) · Respiratory Aspiration (1)
Nervous System Diseases (39) · Neurobehavioral Manifestations (39) · Neurologic Manifestations (39) · Pathological Conditions, Signs and Symptoms (39) · Perceptual Disorders (39) · Signs and Symptoms (39) · Arthritis (3) · Joint Diseases (3) · Musculoskeletal Diseases (3) · Neoplasms (3) · Neoplasms by Site (3) · Pathologic Processes (3) · Rheumatic Diseases (3) · Male Urogenital Diseases (2) · Pain (2)
Bupivacaine (5) · Dexmedetomidine (4) · Ketamine (4) · Ketorolac (4) · Tramadol (4) · Epinephrine (3) · Morphine (3) · Oxycodone (3) · Acetaminophen (2) · Clonidine (2) · Ibuprofen (2) · Ropivacaine (2) · Standard of Care (2) · Analgesia, Patient-Controlled (1) · Etoricoxib (1)
Assiut University (3) · Avenue Therapeutics, Inc. (3) · Benha University (2) · Hospital for Special Surgery, New York (2) · University of Toronto (2) · Wake Forest University Health Sciences (2) · Ain Shams University (1) · Al-Azhar University (1) · Albany Medical College (1) · Bezmialem Vakif University (1) · Emory University (1) · Jessyka Lighthall (1) · Joseph M. Still Research Foundation, Inc. (1) · Kastamonu University (1) · Laboratorios Liomont (1)
United States (15) · Egypt (6) · Canada (4) · France (3) · Turkey (Türkiye) (2) · Belgium (1) · Chile (1) · China (1) · Italy (1) · Mexico (1) · Pakistan (1) · Saudi Arabia (1)
Anna Taddio, PhD (2) · Abdelwahab Saleh (1) · Abeer A Alshami, PhD (1) · Ahmad M Abd El-Rahman, M.D. (1) · Ajay Premkumar, MD (1) · Alexandra Sideris, PhD (1) · Ashok Hemal, MD (1) · Gary Nevins (1) · Gwenyth R Wallen, Ph.D. (1) · Hinzpeter R Jaime, MD (1) · Jessyka Lighthall, MD (1) · Meghan Kirskey, MD (1)
PMID 17464603, PMID 21561303, PMID 22402535, PMID 22535806, PMID 23516031, PMID 24634424, PMID 24719708, PMID 24939863, PMID 25520557, PMID 26810604, PMID 27106963, PMID 27317871, PMID 27501304, PMID 27527817, PMID 29716637, PMID 32683644, PMID 38285446, PMID 40049186, PMID 40701284, PMID 41365300, PMID 41416686
2025 (2), P30CA012197 (1)