2524 completed, 335 terminated, 258 recruiting, 256 unknown. 3650 Phase 3, 651 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD) GV1001 Placebo, GV1001 1.12mg - Moderate to Severe Alzheimer's Disease | Phase 3 | Not yet recruiting | Samsung Pharmaceutical Co., Ltd. | 750 | 2027-07-01 | 2026-06-10 |
| Efficacy and Safety of NTI164 in Children and Young Adults With Rett Syndrome NTI164, Placebo - RETT Syndrome With Proven MECP2 Mutation, Rett Syndrome | Phase 2 / Phase 3 | Not yet recruiting | Fenix Innovation Group | 40 | 2027-07-01 | 2026-09-09 |
| Tricaprilin Phase 3 ALTER-AD (Alternative-Alzheimer Disease) Study Tricaprilin, Placebo - Alzheimer Disease | Phase 3 | Not yet recruiting | Cerecin | 535 | 2027-07-01 | 2026-10-30 |
| Novel Approaches to Supporting Students With ADHD in Multi-Tiered Systems of Support Academic Competency Enhancement (ACE) classroom, School as Usual Classroom Supports - Attention Deficit Hyerpactivity Disorder | Phase 2 / Phase 3 | Not yet recruiting | Florida International University | 544 | 2027-01-01 | 2026-09-28 |
| Dexmedetomidine for Invasive Ventilation In the NEOnate Dexmedetomidine Injectable Solution, Glucose 5% Injectable Solution - Invasive Ventilation, Infant Pain | Phase 2 / Phase 3 | Not yet recruiting | Centre Hospitalier Intercommunal Creteil | 246 | 2027-01-01 | 2026-08-26 |
| Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin pediatric, prolonged released melatonin, Placebo - Post-traumatic Stress Disorder (PTSD), Current Significant Sleep Disturbances | Phase 3 | Not yet recruiting | University Hospital, Strasbourg, France | 120 | 2027-01-01 | 2026-02-18 |
| Stratification and Treatment in Early Psychosis Study -ASSIST CBD 100 mg/mL Oral Solution, Placeb - Treatment Resistant Psychosis, Psychosis | Phase 3 | Not yet recruiting | University of Oxford | 250 | 2027-01-01 | 2026-10-08 |
| A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With Schizophrenia Xanomeline/trospium - Schizophrenia; Psychosis, Cognitive Impairment | Phase 3 | Withdrawn | European Group for Research In Schizophrenia | 2027-01-01 | 2026-10-30 | |
| Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic Syndrome Semaglutide + TAU, Placebo + TAU - Schizophrenia Disorder, Metabolic Syndrome | Phase 3 | Not yet recruiting | All India Institute of Medical Sciences, Bhubaneswar | 600 | 2026-12-01 | 2026-08-18 |
| A Study to Investigate the Effects and Safety of Codabakalner for the Treatment of FXS in Male Participants and Adult Participants With ADS Codabakalner, Placebo - Fragile X Syndrome (FXS), Autism Spectrum Disorder (ASD) | Phase 2 / Phase 3 | Not yet recruiting | Spinogenix | 120 | 2026-12-01 | 2026-10-09 |
| International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial Guideline-directed medical therapy (GDMT), Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI). - Coronary Artery Disease, Cognitive Impairment | Phase 3 | Suspended | NYU Langone Health | 1200 | 2026-12-01 | 2026-06-05 |
| Stratification and Treatment in Early Psychosis Study - PROMOTE Cannabidiol (CBD), Placebo - Clinical High Risk for Psychosis (CHR), Clinical High Risk for Psychosis | Phase 3 | Not yet recruiting | University of Oxford | 586 | 2026-12-01 | 2026-10-08 |
| Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder Kenetik, magnetic resonance imaging scan, Alcohol bar lab - Alcohol Use Disorder, Ketosis | Phase 2 / Phase 3 | Recruiting | University of Pennsylvania | 60 | 2026-12-01 | 2026-10-21 |
| A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial Neuronavigated robotic-enabled TMS, NRX-101, Sham TMS - Treatment Resistant Depression, Treatment Resistant Depression (TRD) | Phase 2 / Phase 3 | Recruiting | NeuroRx, Inc. | 240 | 2026-12-01 | 2026-10-21 |
| A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease Trontinemab, Placebo - Alzheimer's Disease | Phase 3 | Recruiting | Hoffmann-La Roche | 1600 | 2026-11-30 | 2026-10-13 |
| Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days Transcranial magnetic stimulation, Sham transcranial magnetic stimulation - PTSD | Phase 3 | Not yet recruiting | VA Office of Research and Development | 90 | 2026-11-16 | 2026-10-05 |
| Impact on Delirium of the Use of DEXmedetomidine as First-line Sedation in PEDIAtric Intensive Care Dexmedetomidine, Midazolam - Delirium in the Intensive Care Unit | Phase 3 | Not yet recruiting | University Hospital, Tours | 266 | 2026-11-15 | 2026-09-28 |
| Lactium Premedication to Prevent Emergence Agitation Lactium - Lactium, Premedication | Phase 3 | Not yet recruiting | Tanta University | 40 | 2026-11-10 | 2026-10-27 |
| Recovery Management Checkup Scalability and Sustainability Hybrid Experiment Recovery Management Checkups (RMC) delivered by community-based agencies (RMC adopters), Recovery Management Checkups (RMC) delivered by staff under the research team (RMC by research staff) - Substance Use Disorder (SUD), Opioid Use Disorders | Phase 3 | Not yet recruiting | Chestnut Health Systems | 600 | 2026-11-02 | 2026-10-14 |
| Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT), Enhanced Treatment as Usual (ETAU) - Opioid Use Disorder, Chronic Pain | Phase 3 | Not yet recruiting | VA Office of Research and Development | 250 | 2026-11-02 | 2026-09-17 |
Showing 20 of 3650. Sign in to see all of them.
Schizophrenia (462) · Depressive Disorder, Major (437) · Alzheimer Disease (346) · Depression (326) · Bipolar Disorder (229) · Attention Deficit Disorder with Hyperactivity (228) · Anxiety Disorders (186) · Sleep Initiation and Maintenance Disorders (169) · Psychotic Disorders (141) · Dementia (138) · Cognitive Dysfunction (131) · Stress Disorders, Post-Traumatic (129) · Opioid-Related Disorders (128) · Alcoholism (124)
Nervous System Diseases (1060) · Mood Disorders (720) · Pathological Conditions, Signs and Symptoms (638) · Neurocognitive Disorders (624) · Behavior (587) · Signs and Symptoms (553) · Central Nervous System Diseases (519) · Schizophrenia Spectrum and Other Psychotic Disorders (513) · Chemically-Induced Disorders (510) · Brain Diseases (502) · Depressive Disorder (454) · Neurologic Manifestations (425) · Behavioral Symptoms (416) · Substance-Related Disorders (413)
Risperidone (99) · Aripiprazole (96) · Quetiapine Fumarate (91) · Olanzapine (69) · Escitalopram (61) · Cognitive Behavioral Therapy (56) · Methylphenidate (53) · Sertraline (46) · Paliperidone Palmitate (45) · Buprenorphine (44) · Duloxetine Hydrochloride (43) · Vortioxetine (42) · Naltrexone (41) · Dexmedetomidine (37) · Sugars (37)
Eli Lilly and Company (105) · Otsuka Pharmaceutical Development & Commercialization, Inc. (103) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (74) · AstraZeneca (70) · H. Lundbeck A/S (62) · Sanofi (45) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (43) · Shire (40) · Sumitomo Pharma America, Inc. (40) · Pfizer (39) · Yale University (39) · GlaxoSmithKline (38) · New York State Psychiatric Institute (37) · Takeda (36) · Alkermes, Inc. (33)
United States (2006) · Canada (465) · Germany (362) · France (343) · Spain (289) · United Kingdom (246) · Poland (235) · Australia (217) · Italy (209) · Russia (196) · Japan (190) · South Korea (178) · China (173) · Bulgaria (156) · Netherlands (154)
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2025 (30), 2008 (24), 2016 (24), 2015 (22), 2018 (17), 2023 (16), 2009 (15), 2017 (14), 2019 (14), 2014 (10), 2004 (9), 2005 (8), U01AG010483 (5), U01AG059798 (5), R01AG046179 (4)