Attention Deficit Disorder with Hyperactivity: Clinical Trials

1149 completed, 256 unknown, 162 recruiting, 64 terminated. 781 Not applicable, 228 Phase 3, 225 Phase 4, 175 Phase 2, 78 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	781	Completed 454, Unknown 128, Recruiting 96, Not yet recruiting 32, Active not recruiting 26, Terminated 17, Withdrawn 17, Enrolling by invitation 10, Suspended 1
Phase 3	228	Completed 191, Terminated 12, Recruiting 11, Withdrawn 6, Unknown 3, Not yet recruiting 2, Active not recruiting 1, Enrolling by invitation 1, Suspended 1
Phase 4	225	Completed 153, Unknown 27, Terminated 15, Recruiting 14, Withdrawn 10, Not yet recruiting 4, Active not recruiting 2
Phase 2	175	Completed 128, Unknown 18, Recruiting 11, Terminated 11, Not yet recruiting 3, Withdrawn 3, Enrolling by invitation 1
Phase 1	78	Completed 57, Unknown 11, Recruiting 4, Terminated 3, Not yet recruiting 2, Enrolling by invitation 1
Early Phase 1	18	Completed 11, Unknown 3, Enrolling by invitation 1, Not yet recruiting 1, Terminated 1, Withdrawn 1

Follow this condition Literature Review of Attention Deficit Disorder with Hyperactivity trials Research Report on Attention Deficit Disorder with Hyperactivity

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
CBT for Adult Inmates With ADHD PROBECO, Formulation-based cognitive behavioral therapy - Attention Deficit Hyperactivity Disorder	Not applicable	Not yet recruiting	Universidad Europea de Valencia	111	2027-09-01	2026-05-06
A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems	Phase 1 / Phase 2	Not yet recruiting	Hugo W. Moser Research Institute at Kennedy Krieger, Inc.	70	2027-03-01	2026-05-04
Immersive Gamified Virtual Reality-Based Training for Children With Attention Deficit Hyperactivity Disorder Immersive gamified virtual reality-based training (iGameVRT), Traditional social skills training - ADHD, Social Skills	Not applicable	Not yet recruiting	The Hong Kong Polytechnic University	120	2027-01-02	2026-08-25
Novel Approaches to Supporting Students With ADHD in Multi-Tiered Systems of Support Academic Competency Enhancement (ACE) classroom, School as Usual Classroom Supports - Attention Deficit Hyerpactivity Disorder	Phase 2 / Phase 3	Not yet recruiting	Florida International University	544	2027-01-01	2026-09-28
Accelerated and Extended-iTBS Targeting Inhibitory Control in Veterans With ADHD Intermittent Theta-Burst Stimulation, Sham Stimulation - Attention Deficit Disorder With Hyperactivity	Not applicable	Not yet recruiting	VA Office of Research and Development	35	2026-12-01	2026-10-02
Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young Adults With Attention-Deficit/Hyperactivity Disorder and Cannabis Use Disorder Delayed-release, extended-release methylphenidate, Placebo - ADHD, Cannabis Use Disorder	Phase 4	Not yet recruiting	Massachusetts General Hospital	66	2026-11-01	2026-09-28
Developing Virtual Reality Programs to Address Social Skills Deficits in Youth With ADHD VIP Suite - Attention-Deficit/Hyperactivity Disorder (ADHD)	Not applicable	Not yet recruiting	Indiana University	48	2026-11-01	2026-10-20
Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive Psychotherapy Psychotherapy - Irritability, Disruptive Mood Dysregulation Disorder		Recruiting	National Institute of Mental Health (NIMH)	410	2026-10-26	2026-10-21
Augmenting Parent Management Training for Child Temper Outbursts Using a Digital Tool Psychotherapy - Disruptive Behavior Disorders, Conduct Disorder		Recruiting	National Institute of Mental Health (NIMH)	200	2026-10-26	2026-10-21
Development and Effectiveness of a Micro-Psychoeducation Program for Parents of Children With ADHD in Disaster Situations articipants in the intervention group received the micro-psychoeducation program. - Parent Training, Psychoeducation	Not applicable	Not yet recruiting	Kahramanmaras Sutcu Imam University	60	2026-10-15	2026-08-20
Evaluation of Foquest in Adults 65 Years and Older With ADHD Methylphenidate hydrochloride extended-release capsules - Attention Deficit Hyperactivity Disorder	Phase 4	Recruiting	Dar Clinical Research Inc.	36	2026-10-06	2026-10-07
Effectiveness and Security Testing of a Mobile App Mobile app, Treatment as usual - Attention Deficit Disorder With Hyperactivity	Not applicable	Not yet recruiting	Consorci Sanitari del Maresme	80	2026-10-01	2024-09-19
Brief Intervention Addressing Stigma Among Parents of Children With Mental Health Problems Brief video - Depression Disorders, ADHD	Not applicable	Not yet recruiting	New York State Psychiatric Institute	1600	2026-10-01	2026-09-03
ADHD and Mental Effort ADHD		Not yet recruiting	Assistance Publique - Hôpitaux de Paris	80	2026-10-01	2026-09-10
Adult ADHD Symptoms, Depression, Anxiety, and Academic Performance in Medical Students Attention Deficit Hyperactivity Disorder, Depression		Not yet recruiting	Assiut University	52	2026-10-01	2026-09-03
Cardiovascular Safety of Atomoxetine in Children With ADHD Attention Deficit Hyperactivity Disorder		Not yet recruiting	Assiut University	82	2026-09-30	2026-10-05
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) ADHD, Obsessive Compulsive Disorder (OCD)		Recruiting	National Institute of Mental Health (NIMH)	110	2026-09-30	2026-10-05
Decoding Central Defects in Dystrophinopathies From Diagnostic to Remediation Dystrophinopathies		Recruiting	Assistance Publique - Hôpitaux de Paris	110	2026-09-16	2026-09-22
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children 40-Hz non-invasive synchronized audiovisual stimulation - ADHD - Attention Deficit Disorder With Hyperactivity	Phase 1	Not yet recruiting	General Hospital of Ningxia Medical University	80	2026-09-15	2026-07-22
EEG Biomarkers for ADHD Stimulant Treatment methylphenidate HCl, Mixed amphetamine salts extended release - ADHD	Phase 4	Not yet recruiting	Boston Children's Hospital	220	2026-09-15	2026-06-16

Showing 20 of 1788. Sign in to see all of them.

Narrower conditions

Autism Spectrum Disorder (85)  ·  Anxiety Disorders (52)  ·  Spasm (46)  ·  Autistic Disorder (43)  ·  Oppositional Defiant Disorder (43)  ·  Neurodevelopmental Disorders (41)  ·  Depression (38)  ·  Conduct Disorder (34)  ·  Substance-Related Disorders (33)  ·  Bipolar Disorder (29)  ·  Impulsive Behavior (28)  ·  Attention Deficit and Disruptive Behavior Disorders (24)  ·  Mental Disorders (24)  ·  Motor Activity (21)

Broader conditions

Attention Deficit and Disruptive Behavior Disorders (1764)  ·  Mental Disorders (1764)  ·  Neurodevelopmental Disorders (1747)  ·  Nervous System Diseases (214)  ·  Behavior (178)  ·  Pathological Conditions, Signs and Symptoms (167)  ·  Signs and Symptoms (149)  ·  Neurologic Manifestations (133)  ·  Child Development Disorders, Pervasive (110)  ·  Behavioral Symptoms (69)  ·  Central Nervous System Diseases (65)  ·  Neurobehavioral Manifestations (64)  ·  Brain Diseases (61)  ·  Chemically-Induced Disorders (60)  ·  Neuromuscular Manifestations (46)

Interventions

Methylphenidate (216)  ·  Atomoxetine Hydrochloride (118)  ·  Lisdexamfetamine Dimesylate (66)  ·  Therapeutics (35)  ·  Guanfacine (29)  ·  Amphetamine (20)  ·  Dextroamphetamine (18)  ·  SLI381 (18)  ·  Transcranial Direct Current Stimulation (18)  ·  5,10-dihydro-5-methylphenazine (17)  ·  Cognitive Behavioral Therapy (16)  ·  1-(naphthalen-2-yl)-3-azabicyclo(3.1.0)hexane (14)  ·  Sugars (14)  ·  Control Groups (13)  ·  Dexmethylphenidate Hydrochloride (13)

Sponsors

Massachusetts General Hospital (64)  ·  Eli Lilly and Company (53)  ·  Shire (47)  ·  National Taiwan University Hospital (37)  ·  Children's Hospital Medical Center, Cincinnati (36)  ·  Karolinska Institutet (21)  ·  Otsuka Pharmaceutical Development & Commercialization, Inc. (21)  ·  Supernus Pharmaceuticals, Inc. (21)  ·  Florida International University (20)  ·  Duke University (19)  ·  New York State Psychiatric Institute (18)  ·  National Institute of Mental Health (NIMH) (17)  ·  Hospital de Clinicas de Porto Alegre (14)  ·  NYU Langone Health (14)  ·  Assiut University (13)

Countries

United States (795)  ·  Canada (84)  ·  Israel (83)  ·  France (79)  ·  Taiwan (70)  ·  Germany (61)  ·  Sweden (60)  ·  United Kingdom (55)  ·  China (53)  ·  Turkey (Türkiye) (45)  ·  Netherlands (44)  ·  Spain (42)  ·  Italy (34)  ·  Hong Kong (31)  ·  Brazil (29)

Top investigators

Susan Shur-Fen Gau, MD, PhD (21)  ·  Joseph Biederman, MD (16)  ·  Ann Childress, MD (13)  ·  Jeffrey Newcorn, MD (8)  ·  Craig Surman, MD (7)  ·  Thomas Spencer, MD (6)  ·  Timothy Wilens, MD (6)  ·  Chi-Yung Shang, MD (5)  ·  Jonathan Rubin, MD (5)

Results publications

PMID 25019647, PMID 37058600, PMID 35201607, PMID 36971690, PMID 37811711, PMID 41342306, PMID 33600233, PMID 33971070, PMID 34523063, PMID 36847750, PMID 38824626, PMID 21569378, PMID 35690720, PMID 37120522, PMID 38685016, PMID 39128918, PMID 10385840, PMID 11394191, PMID 14595084, PMID 16671928, PMID 18777484, PMID 19318991, PMID 20215923, PMID 20861587, PMID 21156272, PMID 21367347, PMID 21432592, PMID 21824454, PMID 23137723, PMID 23356790, PMID 24290461, PMID 24636025, PMID 25266438, PMID 25877989, PMID 26745211, PMID 27082828, PMID 27118284, PMID 28576350, PMID 28980198, PMID 34057707, PMID 34468332, PMID 34637343, PMID 34714112, PMID 37093628, PMID 40527386, PMID 40975435, PMID 41697570, PMID 42779129, PMID 10433412, PMID 10560028

NIH funding

2023 (5), 2009 (3), R34MH101282 (3), 2008 (2), 2014 (2), 2015 (2), 2025 (2), K24DA016264 (2), R21MH124066 (2), R61MH113663 (2), R61MH131632 (2), U10DA013732 (2), 2017 (1), 2018 (1), 2019 (1)