92 completed, 31 unknown, 16 terminated, 14 withdrawn. 171 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 171 | Completed 92, Unknown 31, Terminated 16, Withdrawn 14, Recruiting 10, Not yet recruiting 7, Active not recruiting 1 |
Follow Leg Injuries: new trials by email Literature Review of Leg Injuries trials Research Report on Leg Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture Suzetrigine (Journavx) - Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia | Phase 4 | Not yet recruiting | Beth Israel Deaconess Medical Center | 79 | 2027-01-05 | 2026-10-29 |
| IRONCARE: Iron Treatment in Older Patients With Hip Fractures Ferric Derisomaltose, Oral Iron (Ferrous sulphate), Placebo IV - Hip Fracture, Anemia | Phase 4 | Not yet recruiting | University of Aarhus | 528 | 2026-10-01 | 2026-06-24 |
| Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction Losartan, Placebo - ACL Injury, ACL Reconstruction | Phase 4 | Not yet recruiting | Rush University Medical Center | 144 | 2026-08-01 | 2025-12-15 |
| Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction Tranexamic Acid (TXA), Placebo - ACL Injury, ACL Tears | Phase 4 | Withdrawn | Campbell Clinic | 2026-04-01 | 2026-03-03 | |
| Haemodynamic Effects and Complications of Continuous Versus Single-shot Spinal Anaesthesia for HIP Fracture Surgery Bupivacaine Spinal 0,5% Heavy - bolus, Bupivacaine Spinal 0,5% Heavy - titration - Anesthesia, Spinal, Hip Fractures | Phase 4 | Not yet recruiting | Centre of Postgraduate Medical Education | 216 | 2026-01-15 | 2026-01-23 |
| Single Shot Exparel vs Catheters in Lower Extremity Trauma Bupivacaine, Exparel + Bupivacaine - Fracture Dislocation of Ankle Joint, Fracture Leg | Phase 4 | Withdrawn | George Washington University | 2025-09-12 | 2026-09-24 | |
| Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia - Fractures, Hip, Femoral Neck Fractures | Phase 4 | Not yet recruiting | University Hospital of Split | 256 | 2025-08-30 | 2025-08-19 |
| Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC) Amnion-Intermediate-Chorion, Standard of Care (SOC) - Diabetic Foot Ulcer | Phase 4 | Completed | Cellution Biologics | 84 | 2025-07-03 | 2026-08-20 |
| The Effects of Intravenous Iron on Mobility in Elderly Patients Following Hip Fracture Surgery Ferric Derisomaltose, Saline (NaCl 0,9 %) (placebo) - Hip Fracture, Anemia | Phase 4 | Recruiting | Soren Overgaard | 210 | 2025-06-09 | 2026-06-01 |
| Preoperative Supra-inguinal Fascia Iliaca Block for Positioning Analgesia in Hip Fracture Patients Undergoing Spinal Anesthesia Isobaric bupivacaine 0.5% - Hip Fractures, Supra-inguinal Fascia Iliaca Block | Phase 4 | Completed | Ghurki Trust and Teaching Hospital | 132 | 2025-06-01 | 2026-04-29 |
| Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery Buprenorphine Transdermal System, Placebo Patch - Pain, Postoperative, Ankle Fracture Surgery | Phase 4 | Recruiting | Jenna-Leigh Wilson | 100 | 2025-04-21 | 2026-04-06 |
| Nalbuphine With Remimazolam Versus Nalbuphine With Propofol for Knee Arthroscopy Nalbuphine, Remimazolam, Propofol - Knee Injuries | Phase 4 | Completed | Wuhan Fourth Hospital | 100 | 2025-04-10 | 2026-09-24 |
| Compression Therapy for Swelling Management Following Ankle Injury Compression sleeve - Ankle Fracture, Ankle Arthrodesis | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 50 | 2025-04-01 | 2025-01-24 |
| IMPLICATION OF FAST-TRACK PROTOCOL FOR HIP FRACTURE FIXATION IN ALEXANDRIA UNIVERSITY HOSPITALS Fast-track protocol for hip fracture fixation - Fast-track Protocol, Hip Fracture | Phase 4 | Completed | Alexandria University | 150 | 2025-04-01 | 2025-12-15 |
| Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG) Liposomal bupivacaine plus bupivacaine, Ropivacaine - Femoral Neck Fractures, Femur Head Necrosis | Phase 4 | Recruiting | Huazhong University of Science and Technology | 60 | 2024-12-04 | 2026-03-13 |
| What Laxative Should be Used After Hip Fracture Surgery? Bisacodyl, Macrogol 3350 and electrolytes, A combination of macrogol 3350 and electrolytes and bisacodyl - Hip Fractures | Phase 4 | Completed | Odense University Hospital | 375 | 2024-10-07 | 2026-10-23 |
| Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture PENG block and cryoablation, fascia iliaca compartment block - Hip Fractures | Phase 4 | Withdrawn | University of Minnesota | 2024-10-01 | 2026-10-16 | |
| Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction Intraosseous Morphine - Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries | Phase 4 | Recruiting | The Methodist Hospital Research Institute | 84 | 2024-08-19 | 2026-04-09 |
| Local Anesthetic for Plateau Fractures Bupivacaine injection, Saline - Tibial Plateau Fractures | Phase 4 | Not yet recruiting | University of Washington | 100 | 2024-08-01 | 2024-06-26 |
| Comparative Assessment of Effectiveness and Safety of L-ESPB Versus Absence of Locoregional Block in Hip Surgery Lumbar Erector Spinae Plane Block. L bupivacaína 0.25% - Hip Fractures, Lumbar Erector Spinae Plane Block | Phase 4 | Unknown | Hospital Álvaro Cunqueiro | 180 | 2024-06-08 | 2024-08-22 |
Showing 20 of 171. Sign in to see all of them.
Hip Fractures (73) · Anterior Cruciate Ligament Injuries (23) · Femoral Neck Fractures (21) · Ankle Injuries (14) · Pain, Postoperative (13) · Ankle Fractures (12) · Femoral Fractures (12) · Pain (11) · Agnosia (10) · Knee Injuries (9) · Tibial Fractures (8) · Anemia (5) · Foot Injuries (5) · Delirium (4) · Hemorrhage (4)
Wounds and Injuries (171) · Fractures, Bone (119) · Hip Injuries (90) · Femoral Fractures (89) · Pathological Conditions, Signs and Symptoms (52) · Signs and Symptoms (37) · Neurologic Manifestations (36) · Pathologic Processes (31) · Knee Injuries (25) · Hip Fractures (18) · Nervous System Diseases (17) · Neurobehavioral Manifestations (15) · Pain (15) · Postoperative Complications (15)
Sodium Chloride (22) · Ropivacaine (18) · Bupivacaine (16) · Tranexamic Acid (12) · Saline Solution (9) · Acetaminophen (8) · Dexamethasone (8) · Morphine (8) · Levobupivacaine (5) · Dexmedetomidine (4) · Oxycodone (4) · Standard of Care (4) · Calcium Dobesilate (3) · Fentanyl (3) · Ibuprofen (3)
University of Aarhus (6) · Hospital for Special Surgery, New York (4) · Hvidovre University Hospital (4) · Poznan University of Medical Sciences (4) · AO Clinical Investigation and Publishing Documentation (3) · Loyola University (3) · Mahidol University (3) · Northwestern University (3) · Odense University Hospital (3) · Akdeniz University (2) · Alexandria University (2) · Centre Hospitalier Universitaire Vaudois (2) · Cork University Hospital (2) · Emory University (2) · Hospital Clinic of Barcelona (2)
United States (51) · Denmark (16) · Spain (13) · Canada (8) · China (8) · Norway (8) · Switzerland (8) · Germany (6) · Poland (6) · South Korea (6) · Turkey (Türkiye) (6) · France (5) · United Kingdom (5) · Belgium (3) · Egypt (3)
Nicolai B Foss, MD (3) · Beate P. Hanson, MD (2) · Eric Swart, MD (2) · John Xerogeanes, MD (2) · Jung Ho Noh, M.D., Ph.D. (2) · Mustafa Serinken, MD (2) · Rune Dueholm Bech, MD (2) · Thomas F. Bendtsen, MD, Ph.d. (2) · Aasis Unnanuntana, MD (1) · Ahmed Shehab, MD (1) · Ahmet B. Erdem (1) · Alan Johnstone, Professor (1)
PMID 33238043, PMID 12548273, PMID 17413915, PMID 18762870, PMID 1015603, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11429362, PMID 11472277, PMID 11890313, PMID 12411815, PMID 12477942, PMID 12560416, PMID 12900694, PMID 14622770, PMID 15029544, PMID 15227616, PMID 15755432, PMID 16056035, PMID 16436852, PMID 17052565, PMID 17138203, PMID 17377133, PMID 17414553, PMID 17414554, PMID 17443116, PMID 17456710, PMID 17543812, PMID 17543813, PMID 17638186, PMID 17720111, PMID 17916782, PMID 17999004, PMID 18042869, PMID 18042893, PMID 18056740, PMID 18073577, PMID 18686750, PMID 19051059, PMID 19157368, PMID 19174373, PMID 19389209, PMID 19690943, PMID 19926634, PMID 19996801, PMID 20124051, PMID 20178889, PMID 20182243, PMID 20578215
2015 (2), 2017 (2), 2004 (1), 2016 (1), K23AR047631 (1)