17 completed, 9 unknown, 2 terminated, 2 withdrawn. 32 Phase 1, 15 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 32 | Completed 17, Unknown 9, Terminated 2, Withdrawn 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 15 | Completed 9, Unknown 3, Withdrawn 2, Terminated 1 |
Follow Leg Injuries: new trials by email Literature Review of Leg Injuries trials Research Report on Leg Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging. Nitroglycerin Ointment 2% - Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia | Phase 1 | Not yet recruiting | Johns Hopkins University | 15 | 2026-11-01 | 2026-03-31 |
| Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau Bupivacain - Tibial Plateau Fractures | Phase 1 | Recruiting | University of Chicago | 38 | 2024-11-01 | 2026-02-05 |
| Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block Pericapsular Nerve Group (PENG) Block - Hip Fractures, Post Operative Pain | Phase 1 | Unknown | Ain Shams University | 60 | 2024-03-01 | 2024-03-05 |
| Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis Ibuprofen and PRP, Acetaminophen and PRP, Placebo and PRP - Osteoarthritis of the Knee, Degenerative Osteoarthritis | Phase 1 / Phase 2 | Withdrawn | QC Kinetix LLC | 2023-11-01 | 2024-10-09 | |
| Exparel vs. ACB With Bupivacaine for ACL Reconstruction Exparel - ACL Tear, Opioid Misuse | Phase 1 | Unknown | Children's Hospital of Orange County | 96 | 2023-10-12 | 2024-02-23 |
| Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury Zoledronic Acid Injection, Placebo - Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture | Phase 1 | Terminated | University of Calgary | 4 | 2023-05-16 | 2025-12-02 |
| Synovial Tissue and Fat Pad Stromal Vascular Fraction Bioengineering in Patients With Knee Articular Cartilage Injury Synovial Tissue and Fat Pad Stromal Vascular Fraction - Cell- and Tissue-Based Therapy, Cartilage Injury | Phase 1 / Phase 2 | Unknown | University of Sao Paulo General Hospital | 10 | 2022-04-01 | 2021-11-15 |
| The Therapeutic Effect of Dau-Di-Wu-Gong in Patient With Ankle Fracture Helminthostachys zeylanica(L.)Hook, Starch - Ankle Fractures | Phase 1 / Phase 2 | Completed | Changhua Christian Hospital | 45 | 2020-12-12 | 2021-08-09 |
| BioACL Reconstruction With Amnion Collagen Matrix Wrap and Stem Cells Case Series Bio-ACL, amnion wrap and BMAC - ACL - Anterior Cruciate Ligament Rupture | Phase 1 | Completed | Andrews Research & Education Foundation | 10 | 2018-01-08 | 2023-02-01 |
| Clinical Study of Platelet-rich Plasma Promoting Tendon-bone Healing in Anterior Cruciate Ligament Reconstruction Platelet-Rich Plasma - Sports Injury | Phase 1 | Unknown | Beijing Tsinghua Chang Gung Hospital | 60 | 2016-07-01 | 2020-12-09 |
| Allogeneic Mesenchymal Stromal Cells in Elderly Patients With Hip Fracture XCEL-MT-OSTEO-BETA, Surgical treatment - Femoral Neck Fracture | Phase 1 / Phase 2 | Withdrawn | Banc de Sang i Teixits | 2015-12-01 | 2017-03-17 | |
| Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block Lidocaine-epinephrine added gadoterate meglumine - Hip Fractures, Anesthesia Local | Phase 1 | Completed | Thomas F. Bendtsen | 26 | 2015-10-01 | 2016-02-12 |
| Vitamin D Supplement for Patients With Tibial Fracture Placebo orally everyday, Vitamin D3 cholecalciferol - Tibial Fracture | Phase 1 | Unknown | Northern Orthopaedic Division, Denmark | 130 | 2015-04-01 | 2015-04-10 |
| EZCast-DFU Study With Portal for Application of Topical Medications Collagenase ointment, Modified Contact Cast System - Foot Ulcer, Diabetic Foot | Phase 1 | Completed | University of Miami | 4 | 2014-10-01 | 2015-06-10 |
| Assessing Foot Injuries in Infantry Recruits Wearing Different Boots Experimental infantry boot - DEFINITE-REGULATOR, Control infantry boot - Blister, Abrasion | Phase 1 / Phase 2 | Completed | Medical Corps, Israel Defense Force | 98 | 2014-08-01 | 2016-06-22 |
| Functional Outcome Comparison of Implant-Free Bone-Patellar Tendon Autograft in Arthroscopic ACL Reconstruction Patella tendon & bone block autograft + press-fit femoral technique, Arthroscopic ACL reconstruction, Hamstring tendon autograft + implant fixation - Anterior Cruciate Ligament Injuries, Ligament; Rupture, Knee, Spontaneous | Phase 1 / Phase 2 | Completed | Universitas Indonesia | 32 | 2013-03-01 | 2019-10-11 |
| Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial eRehab, Formal Physical Therapy - Knee Injuries, Shoulder Injuries | Phase 1 | Completed | Charlotte Sports Medicine Institute, PA | 24 | 2012-07-01 | 2014-01-01 |
| Dexmedetomidine Addition to Fascia Iliaca Compartment Block Fascia iliaca compartment block, Fascia iliaca block - Children With Fracture Femur | Phase 1 | Completed | Mansoura University | 28 | 2012-01-01 | 2015-03-17 |
| Adult Stem Cell Therapy for Repairing Articular Cartilage in Gonarthrosis Autologous MSC knee implantation - Osteoarthritis, Knee, Knee Injuries | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 15 | 2010-10-01 | 2015-12-11 |
| Prospective Randomized Comparison of Bipolar Hemiarthroplasty and Total Hip Arthroplasty With Large Femoral Heads for the Treatment of Displaced Intracapsular Femoral Neck Fractures in the Elderly Total hip arthroplasty, Hemiarthroplasty - Femoral Neck Fractures | Phase 1 | Unknown | Wolfson Medical Center | 80 | 2010-04-01 | 2011-06-17 |
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Anterior Cruciate Ligament Injuries (8) · Knee Injuries (7) · Hip Fractures (4) · Ankle Injuries (3) · Femoral Fractures (3) · Osteoarthritis (3) · Ankle Fractures (2) · Femoral Neck Fractures (2) · Joint Diseases (2) · Osteoarthritis, Knee (2) · Pain (2) · Pain, Postoperative (2) · Patellofemoral Pain Syndrome (2) · Tibial Fractures (2) · Tibial Plateau Fractures (2)
Wounds and Injuries (32) · Fractures, Bone (15) · Knee Injuries (8) · Femoral Fractures (7) · Hip Injuries (6) · Pathological Conditions, Signs and Symptoms (6) · Musculoskeletal Diseases (5) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Arthritis (3) · Joint Diseases (3) · Pain (3) · Pathologic Processes (3) · Postoperative Complications (3)
Bupivacaine (2) · Acetaminophen (1) · Anterior Cruciate Ligament Reconstruction (1) · Arthroplasty, Replacement, Hip (1) · Cholecalciferol (1) · Collagenases (1) · Dental Occlusion (1) · Hemiarthroplasty (1) · Hyaluronic Acid (1) · Ibuprofen (1) · Interleukin 1 Receptor Antagonist Protein (1) · Range of Motion, Articular (1) · Sodium Chloride (1) · Starch (1) · Surgical Procedures, Operative (1)
Hadassah Medical Organization (3) · Banc de Sang i Teixits (2) · University of British Columbia (2) · Ain Shams University (1) · Andrews Research & Education Foundation (1) · Arcadia University (1) · Beijing Tsinghua Chang Gung Hospital (1) · Changhua Christian Hospital (1) · Charlotte Sports Medicine Institute, PA (1) · Children's Hospital of Orange County (1) · Duke University (1) · Johns Hopkins University (1) · Mansoura University (1) · Medical Corps, Israel Defense Force (1) · Mesoblast, Ltd. (1)
United States (10) · Israel (5) · Canada (3) · Denmark (2) · Egypt (2) · Australia (1) · Germany (1) · Norway (1) · Spain (1) · Taiwan (1)
Adam Anz, MD (1) · Adi Fridman, Dr. (1) · Amal Khoury, M.D (1) · Andri MT Lubis, MD, PhD (1) · Anthony Christiano, MD (1) · Babar Shafi, MD, MSPT (1) · Beth E Fisher, PhD, PT (1) · Ching Liang Hsieh, MD, PhD (1) · Christopher Reilly, MD (1) · Dan Gazit, Prof. (1) · Donna Skerrett, MD (1) · Dror Lakstein, MD (1) · Gabi Agar, Dr. (1) · Gideon Man, Dr. (1)
PMID 10037543, PMID 15123925, PMID 15527668, PMID 16002493, PMID 16305269, PMID 16885475, PMID 17767899, PMID 18586222, PMID 18835532, PMID 19460169, PMID 19515102, PMID 21194441, PMID 21248209, PMID 21252603, PMID 22004181, PMID 22273632, PMID 22776554, PMID 22813920, PMID 23209265, PMID 24196464, PMID 25769789, PMID 27266885, PMID 28265448, PMID 28396863, PMID 28768528, PMID 35103026, PMID 8773720, PMID 9362595, PMID 9699158
R03HD041944 (1)