15 completed, 4 terminated, 3 withdrawn, 2 unknown. 8 Phase 4, 6 Phase 2, 5 Phase 1, 4 Phase 3, 3 Not applicable.
Follow Collagenases: new trials by email Literature Review of Collagenases trials Research Report on Collagenases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Negative Pressure Wound Therapy With Instillation of Saline Solution Versus Collagenase Ointment in Full-thickness Wounds Negative Pressure Therapy w/ instillation and dwell (NPWTi-d), Collagenase Ointment - Wounds and Injuries, Wound Healing | Not applicable | Terminated | KCI USA, Inc | 44 | 2018-12-12 | 2024-10-16 |
| Unripe Banana Peel Powder and Lemongrass Oil in Chronic Ulcer gel combined with lemongrass (Cymbopogon citratus) oil at 0.1% concentration, Collagenase ointment, Gel with 10% peel powder of unripe banana - Chronic Ulcer, Healing Ulcer | Phase 1 | Completed | Universidade do Vale do Sapucai | 25 | 2018-02-02 | 2021-07-15 |
| Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's collagenase injection, limited palmar fasciectomy - Dupuytren's Disease | Phase 3 | Completed | McMaster University | 22 | 2017-07-08 | 2023-07-18 |
| Study of SANTYL® vs Hydrogel (SoloSite®) for Pressure Ulcers Santyl, SoloSite® - Pressure Ulcer | Phase 4 | Terminated | Smith & Nephew, Inc. | 3 | 2016-08-01 | 2020-03-10 |
| Use of Santyl Within an Accountable Care Organization Santyl, Standard Care - Pressure Ulcer, Foot Ulcer, Diabetic | Phase 4 | Withdrawn | Smith & Nephew, Inc. | 2016-08-01 | 2017-03-15 | |
| Use of Santyl in Diabetic Foot Ulcers Santyl, Product containing silver - Diabetic Foot, Foot Ulcer, Diabetic | Phase 4 | Completed | Smith & Nephew, Inc. | 102 | 2015-10-01 | 2018-08-01 |
| MEDIHONEY® Gel Versus Collagenase for Wound Debridement Active Leptospermum Honey (Medihoney), Collagenase - Ulcer, Wounds | Not applicable | Terminated | Integra LifeSciences Corporation | 10 | 2015-06-01 | 2017-12-02 |
| Evaluate the Noninferiority of Medicines Treating Uninfected Pressure Ulcers. Collagenase, Kollagenase - Pressure Ulcer | Phase 3 | Withdrawn | Cristália Produtos Químicos Farmacêuticos Ltda. | 2015-01-01 | 2015-07-16 | |
| EZCast-DFU Study With Portal for Application of Topical Medications Collagenase ointment, Modified Contact Cast System - Foot Ulcer, Diabetic Foot | Phase 1 | Completed | University of Miami | 4 | 2014-10-01 | 2015-06-10 |
| Total Occlusion Study in Coronary Arteries - 5 collagenase, saline - Chronic Coronary Total Occlusions | Phase 2 | Completed | Matrizyme Pharma Corporation | 76 | 2014-04-01 | 2016-07-11 |
| Collagenase in the Treatment of Cellulite Collagenase, Biological - Cellulite | Phase 2 | Unknown | Stony Brook University | 20 | 2013-02-01 | 2012-12-12 |
| Long Term Follow Up to Determine the Effects of Collagenase SANTYL Ointment on Scar Formation Santyl - Follow up to Acute Wound Scar Study | Completed | Healthpoint | 12 | 2012-09-01 | 2013-04-15 | |
| The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem Cells collagenase - Alkaline Chemical Burn Of Cornea And Conjunctival Sac, Acid Chemical Burn Of Cornea And Conjunctival Sac | Phase 1 | Unknown | National Taiwan University Hospital | 10 | 2012-01-01 | 2014-07-29 |
| Using Santyl on Diabetic Foot Ulcers Santyl, Control - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 55 | 2011-08-01 | 2014-07-24 |
| MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex XIAFLEX - Dupuytren's Disease | Phase 4 | Completed | Hospital for Special Surgery, New York | 5 | 2011-03-01 | 2017-04-17 |
| Enzymatic Versus (vs) Autolytic Debridement of Diabetic Foot Ulcers Santyl, Tegaderm Hydrogel - Diabetic Foot Ulcers | Phase 4 | Completed | Healthpoint | 20 | 2010-07-01 | 2013-05-31 |
| Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers Negative Pressure Wound Therapy, Collagenase Ointment - Pressure Ulcer, Soft Tissue Necrosis Lower Limb | Not applicable | Terminated | Louisiana State University Health Sciences Center Shreveport | 2 | 2010-06-01 | 2014-07-17 |
| A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers Santyl, White Petrolatum - Diabetic Foot Ulcers | Phase 4 | Completed | Healthpoint | 57 | 2010-06-01 | 2013-05-06 |
| Santyl vs. Sharp Debridement of Diabetic Foot Wounds Santyl, Control - Diabetic Foot Ulcers, Foot Wounds | Phase 4 | Completed | Healthpoint | 48 | 2010-02-01 | 2012-11-21 |
| Collagenase Total Occlusion-1 Trial collagenase - Chronic Total Occlusions | Phase 1 | Completed | Sunnybrook Health Sciences Centre | 28 | 2009-11-01 | 2012-03-23 |
Showing 20 of 25. Sign in to see all of them.
Diabetic Foot (7) · Dupuytren Contracture (4) · Pressure Ulcer (4) · Arthritis (2) · Connective Tissue Diseases (2) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 1 (2) · Diabetes Mellitus, Type 2 (2) · Rare Diseases (2) · Ulcer (2) · Wounds and Injuries (2) · Bursitis (1) · Cellulite (1) · Cicatrix (1) · Foot Injuries (1)
Healthpoint (5) · Smith & Nephew, Inc. (3) · Stony Brook University (3) · State University of New York (2) · Azidus Brasil (1) · Cristália Produtos Químicos Farmacêuticos Ltda. (1) · Hospital for Special Surgery, New York (1) · Integra LifeSciences Corporation (1) · KCI USA, Inc (1) · Louisiana State University Health Sciences Center Shreveport (1) · Matrizyme Pharma Corporation (1) · McMaster University (1) · National Taiwan University Hospital (1) · Sunnybrook Health Sciences Centre (1) · Universidade do Vale do Sapucai (1)
United States (17) · Canada (4) · Brazil (3) · Israel (1) · Netherlands (1) · Taiwan (1)
Herbert B Slade, MD (6) · Marie A Badalamente, PhD (3) · Jaime E Dickerson, PhD (2) · Lawrence C. Hurst (2) · Achilleas Thoma, MD MSc FRCSC (1) · Alexander B Dagum, MD (1) · Bradley Strauss, MD, PhD, FRCP(C) (1) · Christopher Buller, Dr. (1) · Edward Wang, MD (1) · Martha Kelso, RN (1) · Norton Marcos S. Castro, Medic (1) · Ravi Patel, MD (1) · Robert Eichelkraut (1) · Robert S Kirsner, MD, PhD (1)